Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer.

abstract：:Increased in vitro tetraploidy occurred in skin cultures derived from all affected patients and some family members at risk studied in families with heritable colon cancer syndromes (15 of 16 Gardner syndrome families, three Oldfield syndrome families, and four families with heritable colon cancer syndrome without pol...

journal_title：Cancer

authors： Danes BS

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:The improved efficacy of imipenem over other beta-lactam antibiotics in the treatment of febrile neutropenic patients has been attributed to its broad spectrum of activity. METHODS:A prospective, randomized, clinical trial was performed comparing vancomycin 1 g every 12 hours plus imipenem/cilassatin 500 mg...

journal_title：Cancer

authors： Raad II,Whimbey EE,Rolston KV,Abi-Said D,Hachem RY,Pandya RG,Ghaddar HM,Karl CL,Bodey GP

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The Fuhrman grading system is an established predictor of survival in patients with renal cell carcinoma (RCC). The predictive accuracy of various Fuhrman grading schemes was tested with the intent of improving the prediction of RCC-specific survival (RCC-SS). METHODS:The analyses targeted 5453 patients fro...

journal_title：Cancer

authors： Rioux-Leclercq N,Karakiewicz PI,Trinh QD,Ficarra V,Cindolo L,de la Taille A,Tostain J,Zigeuner R,Mejean A,Patard JJ

更新日期：2007-03-01 00:00:00

abstract：:A retrospective analysis of 12 patients with primary central nervous system non-Hodgkin's lymphoma seen from 1958 to 1980 was carried out with emphasis on diagnostic evaluation and treatment results. Computerized tomography (CT) scans were found to be the most valuable diagnostic tool both for initial evaluation as we...

journal_title：Cancer

authors： Mendenhall NP,Thar TL,Agee OF,Harty-Golder B,Ballinger WE Jr,Million RR

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Ovarian tumors of borderline malignancy have a less aggressive behavior and tend to occur at a younger age than their invasive counterparts. The role and extent of fertility-sparing conservative treatments is under continuous evaluation. METHODS:The current study was a retrospective review of 82 patients wi...

journal_title：Cancer

authors： Gotlieb WH,Flikker S,Davidson B,Korach Y,Kopolovic J,Ben-Baruch G

更新日期：1998-01-01 00:00:00

abstract：:Gonadal dosimetry and spermatogenic activity was monitored in patients given radiation therapy (RT) after unilateral orchiectomy for seminoma. The RT given was, with minor variations, 3200 rad in 16 fractions in four weeks to the para-aortic and ipsilateral pelvic inguinal lymphatics in order to include the orchiectom...

journal_title：Cancer

authors： Hahn EW,Feingold SM,Simpson L,Batata M

更新日期：1982-07-15 00:00:00

abstract：:Blood was obtained on 414 occasions from 106 children with acute lymphocytic leukemia (ALL) or solid tumors. Resting and stimulated hexose monophosphate shunt (HMPS) activity and unstimulated and stimulated nitroblue tetrazolium (NBT) dye reduction were assessed on each sample. The values obtained were compared to sim...

journal_title：Cancer

authors： Pickering LK,Anderson DC,Choi S,Feigin RD

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Treatment of febrile neutropenia (FN) is costly, because it typically involves hospitalization. As cancer rates continue to increase, the number of patients suffering from FN will also increase, making it important to quantify the costs of treating this condition accurately and comprehensively. METHODS:A co...

journal_title：Cancer

authors： Lathia N,Mittmann N,DeAngelis C,Knowles S,Cheung M,Piliotis E,Shear N,Walker S

更新日期：2010-02-01 00:00:00

abstract：:Two cases of occult seminoma were observed which showed left-sided lymph node metastases without clinically demonstrable testicular tumors. The peculiar histology of the lymph node metastases, namely PAS-positive tumor cells with clear cytoplasm together with a granulomatous stromal reaction, was highly suggestive of ...

journal_title：Cancer

authors： Richter HJ,Leder LD

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Many experienced oncologists have encountered patients with proven non-small cell lung cancer (NCLC) who received modest doses of palliative radiotherapy (RT) and who unexpectedly survived for > 5 years; some were apparently cured. We used a very large prospective database to estimate the frequency of this p...

journal_title：Cancer

authors： Mac Manus MP,Matthews JP,Wada M,Wirth A,Worotniuk V,Ball DL

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:This study examined the influence of prior treatment on the course of cognitive functioning in breast cancer survivors. Changes in cognitive functioning over time were compared in breast cancer survivors treated with chemotherapy plus radiotherapy, breast cancer survivors treated with radiotherapy only, and ...

journal_title：Cancer

authors： Phillips KM,Jim HS,Small BJ,Laronga C,Andrykowski MA,Jacobsen PB

更新日期：2012-04-01 00:00:00

abstract：:Dual tracer scintigraphy (DTS) (technetium 99m [99mTc] sulfur colloid and gallium 67 citrate [67 gallium citrate]) of the liver and computer subtraction studies (SS) were performed in 26 patients subsequently proven to have hepatocellular carcinoma (HCC) and 32 patients with cirrhosis and focal defects on the colloid ...

journal_title：Cancer

authors： Sostre S,Villagra D,Morales NE,Rivera JV

更新日期：1988-02-15 00:00:00

abstract：:High tissue concentrations of human chorionic gonadotropin (hCG) and alpha-fetoprotein (AFP) were revealed by radioimmunoassay in a hepatic tumor which was surgically removed from a two-year, eight-month-old boy manifesting sexual precocity. Histologically the tumor showed an embryonal type hepatoblastoma admixed with...

journal_title：Cancer

authors： Morinaga S,Yamaguchi M,Watanabe I,Kasai M,Ojima M,Sasano N

更新日期：1983-05-01 00:00:00

abstract：:A patient developed widely metastatic adenoid cystic carcinoma of the parotid gland after several local recurrences. A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C. This is the second complete response ...

journal_title：Cancer

authors： Budd GT,Groppe CW

更新日期：1983-02-15 00:00:00

abstract：:Two hundred seventy-nine consecutive patients with Stage II osteogenic sarcoma of the appendicular skeleton treated between 1976 and 1986 were studied to identify predictors of long-term survival. Survival was 77% and 73% at 5 and 10 years, respectively, with continuously disease-free survival being 70% and 69%. On un...

journal_title：Cancer

authors： Glasser DB,Lane JM,Huvos AG,Marcove RC,Rosen G

更新日期：1992-02-01 00:00:00

abstract：:A prospective randomized trial was performed to evaluate the role of adjuvant local immunostimulation with bacillus Calmette-Guérin (BCG) in resected Stage I and Stage II non-small cell bronchogenic carcinoma. The patients were stratified according to extent of resection and surgical stage, and randomized to treatment...

journal_title：Cancer

authors：

更新日期：1986-12-01 00:00:00

abstract：:Forty-six cases of resected lung cancer, including 20 cases at Stages I and II and 26 cases at Stage III (N2), were subdivided into two groups: a good prognosis group with a longer survival period and a poor prognosis group in which the patients died earlier of the cancer. From paraffin-embedded lymph node tissues of ...

journal_title：Cancer

authors： Ogawa J,Iwazaki M,Tsurumi T,Inoue H,Shohtsu A

更新日期：1991-03-01 00:00:00

abstract：:Metastatic tumors to the mucosa of the stomach are unusual occurrences that can cause clinical and pathologic problems in diagnosis. The authors report 67 cases from the files of the Veterans Administration Center at Houston. Ten cases were found on endoscopic biopsy and 57 at necropsy. Each patient endoscopically eva...

journal_title：Cancer

authors： Green LK

更新日期：1990-04-01 00:00:00

abstract：:The prognostic importance of various factors was analyzed for 347 patients registered by the Mycosis Fungoides Cooperative Group (MFCG). Extent of skin involvement at the time of registration and number of sites of clinically enlarged lymph nodes were clearly the most important prognostic variables, and were combined ...

journal_title：Cancer

authors： Green SB,Byar DP,Lamberg SI

更新日期：1981-06-01 00:00:00

abstract：:Mixed cellularity Hodgkin's disease and diffuse non-Hodgkin's lymphoma, mixed cell type, occurred consecutively in a husband and wife. Both patients demonstrated monoclonal IgM gammopathies. The unusual nature and possible significance of these findings are discussed. ...

journal_title：Cancer

authors： Offit K,Macris NT,Hellman G,Rotterdam HZ

更新日期：1986-01-15 00:00:00

abstract：BACKGROUND:The growth of cancer symptom management research has been limited by challenges of slow recruitment and under-enrollment. One potential solution to this problem is the use of screening questions that identify patients who are interested in participating in research. The goal of this study was to evaluate thi...

journal_title：Cancer

authors： Crowley R,Casarett D

更新日期：2003-05-01 00:00:00

abstract：:The role of hyperthermic isolation perfusion in the treatment of advanced melanoma of the limbs is clearly important. However, attention has in the past been focussed mainly on surgical aspects of the procedure. Whereas, equivalent interest in chemotherapy considerations has been lacking. A group of 15 patients have b...

journal_title：Cancer

authors： Klein ES,Ben-Ari GY

更新日期：1987-03-15 00:00:00

abstract：:Extrarenal Wilms' tumor is a very rare disease, occurring mostly in children. Sixteen cases have been reported in the world medical literature. A case of retroperitoneal extrarenal Wilms' tumor is reported in a 36-year old white male and the literature reviewed. Pathologic examination revealed both undifferentiated re...

journal_title：Cancer

authors： Koretz MJ,Wang S,Klein FA,Lawrence W Jr

更新日期：1987-11-15 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) require intensive and extensive therapy, which seems impracticable in elderly patients due to hematologic and extrahematologic toxicity. Consequent dose reduction and therapy attenuation can reduce treatment-related toxicity but also decreases therapeutic e...

journal_title：Cancer

authors： Rigacci L,Carpaneto A,Alterini R,Carrai V,Bernardi F,Bellesi G,Longo G,Bosi A,Rossi Ferrini P

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Ependymomas account for 2% of all intracranial tumors in adults. Supratentorial ependymomas are less common than their infratentorial counterparts. To the authors' knowledge to date, the predictive values of surgery, histology, and patient-related prognostic factors for these tumors remain unresolved. The au...

journal_title：Cancer

authors： Metellus P,Figarella-Branger D,Guyotat J,Barrie M,Giorgi R,Jouvet A,Chinot O,Club de Neuro-Oncologie de la Société Française de Neurochirurgie and the Association des Neuro-Oncologues d'Expression Française.

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Nearly 50% of urothelial carcinoma patients with lymph node-negative invasive cancers recur after radical surgery. In many cases, occult local or lymph node disease may be present but undetectable by current approaches. Reverse-transcriptase polymerase chain reaction (RT-PCR)-detectable mRNA of Uroplakin II ...

journal_title：Cancer

authors： Copp HL,Chin JL,Conaway M,Theodorescu D

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Race is associated with patterns of presentation and survival outcomes of gastric cancer in the United States. However, the impact of race on the receipt of guideline-recommended care is not well characterized. By using current recommendations, the authors examined the association between race and guideline-...

journal_title：Cancer

authors： Al-Refaie WB,Gay G,Virnig BA,Tseng JF,Stewart A,Vickers SM,Tuttle TM,Feig BW

更新日期：2010-01-15 00:00:00

abstract：:A case-referent study on soft tissue sarcomas (STS) was conducted, to see if previous findings regarding an association between exposure to phenoxyacetic acids or chlorophenols and this tumor type could be reproduced. Fifty-five male STS patients were thereby compared with 220 living and 110 dead population-based refe...

journal_title：Cancer

authors： Hardell L,Eriksson M

更新日期：1988-08-01 00:00:00

abstract：:Fluorescence polarization was performed on 82 individuals: 32 patients with malignant diseases, 30 apparently healthy individuals, and 20 patients with nonmalignant diseases. The blood lymphocytes from these cases were isolated and challenged with cancer basic protein (CaBP). Stimulation occurred in the majority of th...

journal_title：Cancer

authors： Schnuda ND

更新日期：1980-09-01 00:00:00

abstract：:This is a statistical analysis of the use of mammography in the symptomatic patient. Eighty-eight percent of women older than 50 years who had a palpable cancer of the breast had a positive mammogram; only 57% of women younger than 51 years of age had a positive mammogram. When the cancer presented as nipple discharge...

journal_title：Cancer

authors： Edeiken S

更新日期：1989-04-01 00:00:00