Prognostic ability of simplified nuclear grading of renal cell carcinoma.

abstract：BACKGROUND:The effects of relaxin (RLX) on the human breast adenocarcinoma cell line MCF-7 have been evaluated. METHODS:The cells were maintained in culture with Dulbecco's modified Eagle's medium with 1% and 10% fetal calf serum. Highly purified porcine RLX was added at concentrations ranging between 10(-11) and 10(-...

journal_title：Cancer

authors： Bigazzi M,Brandi ML,Bani G,Sacchi TB

更新日期：1992-08-01 00:00:00

abstract：:Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells plays an important role in Fas-mediated tumor killing, During tumor progression FasL-expressing tumor cells are involved in counterattacking to kill tumor-infiltrating lymphocytes (TILs). Soluble Fa...

journal_title：Cancer

authors： Kim R,Emi M,Tanabe K,Uchida Y,Toge T

更新日期：2004-06-01 00:00:00

abstract：:The Southwest Oncology Group in a prospective randomized study compared one year of adjuvant combination chemotherapy with continuous CMFVP to two years of intermittent L-PAM in women with operable breast cancer with histologically positive axillary lymph nodes. In fully evaluable patients with a 42-month median and 3...

journal_title：Cancer

authors： Glucksberg H,Rivkin SE,Rasmussen S,Tranum B,Gad-el-Mawla N,Costanzi J,Hoogstraten B,Athens J,Maloney T,McCracken J,Vaughn C

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:There are few reports comparing the clinicopathologic features of sarcomas of the aorta (SA), sarcomas of the inferior vena cava (SIVC), and sarcomas of the pulmonary artery (SPA). METHODS:The authors retrospectively reviewed 11 SA, 16 SIVC, and 16 SPA, and compared clinical, pathologic, and immunohistochem...

journal_title：Cancer

authors： Burke AP,Virmani R

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Programmed death 1 (PD-1) signaling in the tumor microenvironment dampens immune responses to cancer, and blocking this axis induces antitumor effects in several malignancies. Clinical studies of PD-1 blockade are only now being initiated in pediatric patients, and little is known regarding programmed death-...

journal_title：Cancer

authors： Majzner RG,Simon JS,Grosso JF,Martinez D,Pawel BR,Santi M,Merchant MS,Geoerger B,Hezam I,Marty V,Vielh P,Daugaard M,Sorensen PH,Mackall CL,Maris JM

更新日期：2017-10-01 00:00:00

abstract：:The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome. With this in mind, the relationship between nuclear DNA content and both prognosis and histologic grading according to...

journal_title：Cancer

authors： Vogt T,Stolz W,Braun-Falco O,Kaudewitz P,Eckert F,Abmayr W,Dummer R,Burg G

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:The carboplatin-based chemotherapeutic regimen M-CAVI (methotrexate, carboplatin, and vinblastine) is active against bladder carcinoma and can be administered to patients who are ineligible to receive cisplatin or doxorubicin. The authors designed a randomized study to evaluate whether M-CAVI offers a therap...

journal_title：Cancer

authors： Bellmunt J,Ribas A,Eres N,Albanell J,Almanza C,Bermejo B,Solé LA,Baselga J

更新日期：1997-11-15 00:00:00

abstract：:In contrast with the expectations of the authors and with reports suggesting a decline in risk for scrotal cancer, Connecticut Tumor Registry data neither showed detectable decrease in risk over the 45-year-period for all 95 scrotal malignancies nor for the 71 epithelial cancers. The age distribution of scrotal cancer...

journal_title：Cancer

authors： Roush GC,Schymura MJ,Flannery JT

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Patients with testicular cancer can be cured by cisplatin-based chemotherapy in many cases. Thus, concern about possible late toxicities of treatment is warranted. METHODS:In this investigation, the absolute number of natural killer (NK) cells according to their CD56+ phenotype, NK cell activity, and antibo...

journal_title：Cancer

authors： Krainer M,Wolf H,Michl I,Wiltschke C,Budinsky A,Kaider A,Kratzik C,Eibl MM,Zielinski CC

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:The optimal imaging for the staging of oropharyngeal cancer is not well defined. METHODS:The linked Surveillance, Epidemiology, and End Results (SEER)-Medicare database for 2006 through 2011 was used to compare patient characteristics and hospital region by the initial imaging modality used for patients wit...

journal_title：Cancer

authors： Morgan RL,Eguchi MM,Mueller AC,Daugherty SL,Amini A,Karam SD

更新日期：2019-08-15 00:00:00

abstract：:A series of 108 prospectively collected human pancreata were evaluated histologically for the presence of acinar cell and ductal lesions. Foci of dysplastic acinar cells were present in 44% of the series. Some of the focal acinar cell abnormalities were similar to atypical acinar cell nodules which have been described...

journal_title：Cancer

authors： Longnecker DS,Shinozuka H,Dekker A

更新日期：1980-02-01 00:00:00

abstract：:The diagnosis of malignant melanoma is based on clinical grounds and a properly performed biopsy, preferably excision, so that the type of melanoma and the thickness can be assessed by methods described by Clark and Breslow. These facilitate clinical and pathologic staging. Excisions with conservative margins for thin...

journal_title：Cancer

authors： Harris MN,Shapiro RL,Roses DF

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to present planning, feasibility, toxicity, and outcome of helical tomotherapy for spinal cord-sparing reirradiation of spinal metastases and tumors. METHODS:Thirty-six patients with spinal metastases and tumors who had undergone previous radiotherapy were reirradiated with hel...

journal_title：Cancer

authors： Sterzing F,Hauswald H,Uhl M,Herm H,Wiener A,Herfarth K,Debus J,Krempien R

更新日期：2010-08-15 00:00:00

abstract：BACKGROUND:Hypercalcemia has rarely been reported in patients with Richter's syndrome (RS). In this article, the authors report four cases with complementary pathophysiologic examinations. METHODS:Four patients with hypercalcemia that indicated RS were admitted to the study unit between 1980 and 1994 with the followin...

journal_title：Cancer

authors： Beaudreuil J,Lortholary O,Martin A,Feuillard J,Guillevin L,Lortholary P,Raphael M,Casassus P

更新日期：1997-03-15 00:00:00

abstract：BACKGROUND:Chordoma and chondrosarcoma of the skull base are frequently amalgamated because of similar anatomic location, clinical presentation, and radiologic findings. The chondroid chordoma variant has been reported to carry a better prognosis. The objective of the current study was to investigate the distinctions b...

journal_title：Cancer

authors： Almefty K,Pravdenkova S,Colli BO,Al-Mefty O,Gokden M

更新日期：2007-12-01 00:00:00

abstract：:In a former series of 60 resected Stage II nonseminomatous germinal testis tumors the authors succeeded in demonstrating that adjuvant cisplatin, vinblastine, and bleomycin (PVB) was able to significantly improve survival (100% in 11 treated versus 28.5% in 7 historical controls, P less than 0.01) only in patients wit...

journal_title：Cancer

authors： Pizzocaro G,Zanoni F,Milani A,Piva L,Salvioni R,Pasi M,Pilotti S,Monfardini S

更新日期：1984-03-15 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether estramustine (estrogen mustard [EM]) is a promising alternative in the treatment of patients with epithelial ovarian carcinoma (OVCA). EM is a microtubule-associated protein (MAP) specific antimicrotubule agent with low toxicity. METHODS:The authors investigated ...

journal_title：Cancer

authors： Chen Z,Fadiel A,Jia JF,Sakamoto H,Carbone R,Naftolin F

更新日期：1999-06-15 00:00:00

abstract：:Ultrasonographic examinations and measurements of CA 19-9 and elastase 1 were done simultaneously in 14 patients with resectable pancreatic cancer of less than 3.0 cm in longest diameter and 48 patients with pancreatitis. Although a pancreatic mass was detected ultrasonically in only six (42.9%) of the patients with t...

journal_title：Cancer

authors： Iishi H,Yamamura H,Tatsuta M,Okuda S,Kitamura T

更新日期：1986-05-15 00:00:00

abstract：:Thyroglobulin messenger RNA (mRNA) was located and quantified in tissue sections of differentiated human thyroid cancers by in situ hybridization using cloned complementary DNA probes. The cells of the well-differentiated follicular and papillary forms contained similar levels of thyroglobulin mRNA, corresponding to a...

journal_title：Cancer

authors： Bergé-Lefranc JL,Cartouzou G,De Micco C,Fragu P,Lissitzky S

更新日期：1985-07-15 00:00:00

abstract：BACKGROUND:Clear cell tumors of the thyroid gland in general are uncommon. Metastatic renal cell carcinoma (RCC) to the thyroid gland is a rare occurrence but must be considered in the differential diagnosis of a thyroid gland clear cell neoplasm to prevent misclassification, potentially resulting in inappropriate clin...

journal_title：Cancer

authors： Heffess CS,Wenig BM,Thompson LD

更新日期：2002-11-01 00:00:00

abstract：:Nuclear DNA content of paraffin-embedded tissue from 48 adrenocortical neoplasms, 18 histologically normal control adrenal glands, and five hyperplastic adrenal glands was analyzed retrospectively using flow cytometry. Aneuploidy was compared with morphologic criteria as a predictor of recurrence. All 18 controls, fiv...

journal_title：Cancer

authors： Amberson JB,Vaughan ED Jr,Gray GF,Naus GJ

更新日期：1987-06-15 00:00:00

abstract：:A case of fatal acute hepatic vein thrombosis occurred during treatment for Hodgkin's disease. At necropsy no evidence of Hodgkin's disease or obliterative venoocclusive disease of the liver was found. We speculate that Adriamycin, DTIC and/or vinblastine may have been responsible for this unusual disorder. ...

journal_title：Cancer

authors： Houghton AN,Shafi N,Rickles FR

更新日期：1979-12-01 00:00:00

abstract：:Two female patients with desmoid tumors (aggressive fibromatosis) showed tumor regression after endocrine therapy. In one patient, tumor response to tamoxifen has been maintained over several years of treatment. In the second patient, who had inoperable mesenteric fibromatosis, the tumor progressed on tamoxifen but re...

journal_title：Cancer

authors： Wilcken N,Tattersall MH

更新日期：1991-09-15 00:00:00

abstract：BACKGROUND:Well differentiated (WD) and dedifferentiated (DD) retroperitoneal liposarcoma (RPLS) have distinct biologic behaviors. Consequently, the therapeutic approaches for these tumors differ and mandate an accurate preoperative diagnosis. The authors of this report evaluated whether computed tomography (CT) can be...

journal_title：Cancer

authors： Lahat G,Madewell JE,Anaya DA,Qiao W,Tuvin D,Benjamin RS,Lev DC,Pollock RE

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Recently, a 23-gene signature was developed to produce a melanoma diagnostic score capable of differentiating malignant and benign melanocytic lesions. The primary objective of this study was to independently assess the ability of the gene signature to differentiate melanoma from benign nevi in clinically re...

journal_title：Cancer

authors： Clarke LE,Flake DD 2nd,Busam K,Cockerell C,Helm K,McNiff J,Reed J,Tschen J,Kim J,Barnhill R,Elenitsas R,Prieto VG,Nelson J,Kimbrell H,Kolquist KA,Brown KL,Warf MB,Roa BB,Wenstrup RJ

更新日期：2017-02-15 00:00:00

abstract：:The radionuclide, gallium-67, accumulates in a wide variety of neoplastic and inflammatory lesions. Diffuse bilateral lung localization of 67Ga occurred in two cases of interstitial pneumonitis associated with bleomycin therapy. Clinical symptoms and laboratory evaluation of pulmonary status correlated with scintigrap...

journal_title：Cancer

authors： Richman SD,Levenson SM,Bunn PA,Flinn GS,Johnston GS,DeVita VT

更新日期：1975-12-01 00:00:00

abstract：:Research trends on quality of life outcomes for cancer survivors are discussed. Epidemiologic data indicate that female cancer survivors, coming primarily from patient groups with gynecologic, breast, and colorectal cancers, will outnumber male survivors 3 to 1. Male survivors will come from the ranks of patient group...

journal_title：Cancer

authors： Andersen BL

更新日期：1994-08-15 00:00:00

abstract：:The interferon (IFN) assay of the sera from the 40 patients with head and neck cancer was performed by the plaque-reduction assay with vesicular stomatitis virus in FL cells derived from human amniotic membrane. The patients mainly had Stage III or IV lesion without distant metastasis, and previously had not received ...

journal_title：Cancer

authors： Sato M,Yoshida H,Yanagawa T,Yura Y,Urata M,Atsumi M,Furumoto N,Hayashi Y,Takegawa Y

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to analyze the extent of hypoxia in prostate carcinoma tumors using the Eppendorf pO(2) microelectrode and correlate this with pretreatment characteristics and prognostic factors. METHODS:Custom-made Eppendorf pO(2) microelectrodes were used to obtain pO(2) measurements from th...

journal_title：Cancer

authors： Movsas B,Chapman JD,Greenberg RE,Hanlon AL,Horwitz EM,Pinover WH,Stobbe C,Hanks GE

更新日期：2000-11-01 00:00:00

abstract：:An infant who presented with a thigh mass and coagulopathy was found to have a hemangioendothelioma. The tumor rapidly enlarged despite accepted therapeutic modalities, and the child died after a sudden cardiac arrest. Postmortem examination revealed a highly invasive tumor mass that had infiltrated the bowel and invo...

journal_title：Cancer

authors： Weinblatt ME,Kahn E,Kochen JA

更新日期：1984-11-15 00:00:00