An immunohistochemical study of hepatoblastoma producing human chorionic gonadotropin.

Abstract:

:High tissue concentrations of human chorionic gonadotropin (hCG) and alpha-fetoprotein (AFP) were revealed by radioimmunoassay in a hepatic tumor which was surgically removed from a two-year, eight-month-old boy manifesting sexual precocity. Histologically the tumor showed an embryonal type hepatoblastoma admixed with multinucleated tumor giant cells. The localization of native hCG and hCG-beta subunit was immunohistochemically demonstrated in some of the above giant cells, while that of alpha-fetoprotein was diffusely in the tumor cells of hepatoblastoma of embryonal type. Ultrastructural features of the giant cells were also presented.

journal_name

Cancer

journal_title

Cancer

authors

Morinaga S,Yamaguchi M,Watanabe I,Kasai M,Ojima M,Sasano N

doi

10.1002/1097-0142(19830501)51:9<1647::aid-cncr2820

subject

Has Abstract

pub_date

1983-05-01 00:00:00

pages

1647-52

issue

9

eissn

0008-543X

issn

1097-0142

journal_volume

51

pub_type

杂志文章

相关文献

CANCER文献大全
  • Non-Hodgkin's lymphoma in bone. Pathologic and radiologic features with clinical correlates.

    abstract::Thirty-seven lymphomas of bone were studied, including 33 diffuse large cell lymphomas, three undifferentiated (small noncleaved cell) lymphomas, and one well-differentiated (small) lymphocytic lymphoma. The large cell lymphomas were subclassified as large cleaved, large noncleaved, multilobated cell, and immunoblasti...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19871115)60:10<2494::aid-cncr282

    authors: Clayton F,Butler JJ,Ayala AG,Ro JY,Zornoza J

    更新日期:1987-11-15 00:00:00

  • Transbronchial lung biopsy in the diagnosis of lymphangitic carcinomatosis.

    abstract::The clinical diagnosis of lymphangitic carcinomatosis of the lung has generally been confirmed by open lung or transthoracic needle biopsy, precedures with significant morbidity and mortality, particularly in patients with respiratory insufficiency. We present six cases of lymphangitic carcinomatosis diagnosed by tran...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197810)42:4<1995::aid-cncr282042

    authors: Aranda C,Sidhu G,Sasso LA,Adams FV

    更新日期:1978-10-01 00:00:00

  • Prognostic significance of treatment-induced pathologic necrosis in extremity and truncal soft tissue sarcoma after neoadjuvant chemoradiotherapy.

    abstract:BACKGROUND:Histologic response to chemotherapy has been shown to be an independent prognostic factor in patients with osteosarcoma and Ewing sarcoma. However, in patients with soft tissue sarcoma (STS), the prognostic impact of histologic response to chemotherapy is less clear. In the current study, the authors sought ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28945

    authors: Mullen JT,Hornicek FJ,Harmon DC,Raskin KA,Chen YL,Szymonifka J,Yeap BY,Choy E,DeLaney TF,Nielsen GP

    更新日期:2014-12-01 00:00:00

  • Solid tumor models for the assessment of different treatment modalities. XIII. Comparison of response and recovery of host and solid tumor to cyclophosphamide and radiation.

    abstract::A study of the effects of local tumor radiation alone (1500R) and cyclophosphamide alone (150 mg/kg) on the experimental solid tumor rat hepatoma 3924A has been completed. Cyclophosphamide was more effective in controlling tumor growth than either radiation or 5-fluorouracil (5-FU) (150 mg/kg) previously reported. Par...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800601)45:11<2793::aid-cncr282

    authors: Looney WB,Hopkins HA,Grover WH,Macleod MS,Ritenour ER,Hobson AS

    更新日期:1980-06-01 00:00:00

  • Ovarian dysplasia: nuclear texture analysis.

    abstract:BACKGROUND:Ovarian dysplasia has been defined by histologic and morphometric studies focusing on architectural and nuclear profile changes. A new technique is used to enhance the accuracy of this diagnosis by a quantitative evaluation of the nuclear texture that represents the nuclear chromatin pattern on which convent...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931201)72:11<3253::aid-cncr282

    authors: Deligdisch L,Miranda C,Barba J,Gil J

    更新日期:1993-12-01 00:00:00

  • Evaluation of size in prognosis of oral cancer.

    abstract::Greatest surface diameter of a cancer, together with suspicion of regional node metastasis, forms the basis for prognosis through the clinical TNM staging system for many cancers. In oral cancer, however, surface size sometimes fails to correlate, or sometimes inversely correlates, with tumor aggressiveness. To shed l...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860701)58:1<158::aid-cncr28205

    authors: Moore C,Flynn MB,Greenberg RA

    更新日期:1986-07-01 00:00:00

  • Improvement of in vitro mitogen proliferative responses in non-Hodgkin's lymphoma patients exposed to fractionated total body irradiation.

    abstract::Patients with non-Hodgkin's lymphomas who failed to respond to chemotherapy were treated with low dose fractionated total body irradiation (TBI). Prior to during and after scheduled therapy, their clinical status was evaluated and peripheral blood studies were performed to enumerate EAC and E rosetting cells and to me...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197809)42:3<1204::aid-cncr282042

    authors: Yonkosky DM,Feldman MI,Cathcart ES,Kim S

    更新日期:1978-09-01 00:00:00

  • Current trends in patient enrollment for robotic-assisted laparoscopic prostatectomy in Belgium.

    abstract:BACKGROUND:During the last decade, an inverse stage migration has been observed in radical prostatectomy series at tertiary centers. However, it remains unclear whether similar trends can also be observed in solely robotic practices, including nonreferral centers. The aim of this study was to investigate the clinical a...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.30874

    authors: Albisinni S,Joniau S,Quackels T,De Coster G,Dekuyper P,Van Cleynenbreugel B,Van Damme N,Van Eycken E,Ameye F,Roumeguère T,Be-RALP Registry (Belgian Robotic-Assisted Laparoscopic Prostatectomy Registry).

    更新日期:2017-11-01 00:00:00

  • Anaplastic astrocytoma of the adult cerebrum. Prognostic value of histologic features.

    abstract::Initial biopsy and resection specimens from 78 cerebral astrocytomas with anaplastic foci occurring in adults were examined for the presence of five specific histologic features traditionally considered indicative of anaplasia. Anaplastic astrocytomas with foci of tumor necrosis had been classified as glioblastoma mul...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850301)55:5<928::aid-cncr28205

    authors: Fulling KH,Garcia DM

    更新日期:1985-03-01 00:00:00

  • Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trial.

    abstract::To assess the value in Ewing's sarcoma of a new multiagent therapy (vincristine, cyclophosphamide, Adriamycin, (doxorubicin) procarbazine), 30 children with a localized tumor (eight distal, nine proximal, 13 central lesions) treated at the Institut Gustave-Roussy between 1973 and 1976 (E3), were pair-matched by site o...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19830801)52:3<415::aid-cncr28205

    authors: Zucker JM,Henry-Amar M,Sarrazin D,Blache R,Patte C,Schweisguth O

    更新日期:1983-08-01 00:00:00

  • Barriers to effective treatment of pediatric solid tumors in middle-income countries: can we make sense of the spectrum of nonbiologic factors that influence outcomes?

    abstract:BACKGROUND:The delivery of effective treatment for pediatric solid tumors poses a particular challenge to centers in middle-income countries (MICs) that already are vigorously addressing pediatric cancer. The objective of this study was to improve the current understanding of barriers to effective treatment of pediatri...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.28339

    authors: Friedrich P,Ortiz R,Fuentes S,Gamboa Y,Ah Chu-Sanchez MS,Arambú IC,Montero M,Báez F,Rodríguez-Galindo C,Antillón-Klussmann F,Central American Association of Pediatric Hematologists and Oncologists (AHOPCA).

    更新日期:2014-01-01 00:00:00

  • The relation of flow cytometry to clinical and biologic characteristics in women with node negative primary breast cancer.

    abstract::Flow cytometry (FC) analysis including DNA index (ploidy status) and cell kinetics (%S and %S + G2/M) was done on frozen tissue of the primary lesions of 101 women with node negative (N-) breast cancer who were studied prospectively. Currently, 19% (19/101) of the patients have recurred. No significant relations have ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19891101)64:9<1894::aid-cncr2820

    authors: Muss HB,Kute TE,Case LD,Smith LR,Booher C,Long R,Kammire L,Gregory B,Brockschmidt JK

    更新日期:1989-11-01 00:00:00

  • Adenocarcinoma of prostate presenting as brain metastasis.

    abstract::The diagnosis of brain metastasis from prostate carcinoma is rarely made antemortem, and has previously been reported only in patients with known extensive metastatic disease of long duration. A case of adenocarcinoma of the prostate presenting as a brain metastasis is described. Current concepts of metastatic spread ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19841015)54:8<1723::aid-cncr2820

    authors: Baumann MA,Holoye PY,Choi H

    更新日期:1984-10-15 00:00:00

  • Preclinical and clinical studies of interferons and interferon inducers in breast cancer.

    abstract::Preclinical and clinical studies suggest interferons and interferon inducers have antitumor activity for breast carcinoma. Observations include inhibition of growth of freshly derived and continuously passaged breast carcinoma cells in vitro, decreased tumor size and increased survival in spontaneous mouse mammary car...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19840201)53:3+<783::aid-cncr2820

    authors: Borden EC,Balkwill FR

    更新日期:1984-02-01 00:00:00

  • Concurrent vinblastine and radiation therapy in bladder cancer.

    abstract:BACKGROUND:Since mid-1987, 29 patients with invasive transitional cell carcinoma of the urinary bladder (T1-3 N0-X M0) were treated with concurrent radiation therapy (RT) (target dose [TD], 62-66 Gy) 1.8-2.0 Gy/day for 5 days a week with a break in the middle of treatment of 2-3 weeks and vinblastine weekly 2 mg/5-12 h...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19921215)70:12<2885::aid-cncr282

    authors: Kragelj B,Jereb B,Kragelj L,Stanonik M

    更新日期:1992-12-15 00:00:00

  • Imaging hepatic neoplasms.

    abstract::The various radiologic methods used in the detection of hepatic lesions in the oncologic patient are discussed. The advantages and disadvantages of each imaging technique as well as a new diagnostic approach are also discussed. With the rapid technological advances made in cross-sectional imaging, the authors believe ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Bernardino ME,Lewis E

    更新日期:1982-12-01 00:00:00

  • Evaluation of chromosome aneuploidy in tissue sections of preinvasive breast carcinomas using interphase cytogenetics.

    abstract:BACKGROUND:Little is known about cellular level genetic alterations in preinvasive breast lesions, particularly lobular carcinoma in situ. METHODS:We employed fluorescence in situ hybridization (FISH) using pericentromeric (alpha satellite) probes to assess numerical alterations of chromosomes 1, 7, 8, 16, 17, and X i...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960115)77:2<315::AID-CNC

    authors: Visscher DW,Wallis TL,Crissman JD

    更新日期:1996-01-15 00:00:00

  • Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor.

    abstract:BACKGROUND:Hemangiopericytomas and malignant solitary fibrous tumors (HPC/SFT) are rare, closely related sarcomas with unpredictable behavior that respond infrequently to chemotherapy. An optimal systemic treatment strategy for advanced HPC/SFT has not yet been identified. METHODS:We retrospectively analyzed the recor...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26098

    authors: Park MS,Patel SR,Ludwig JA,Trent JC,Conrad CA,Lazar AJ,Wang WL,Boonsirikamchai P,Choi H,Wang X,Benjamin RS,Araujo DM

    更新日期:2011-11-01 00:00:00

  • Changes associated with the development of resistance to imatinib (STI571) in two leukemia cell lines expressing p210 Bcr/Abl protein.

    abstract:BACKGROUND:Although various mechanisms have been recognized as being associated with the development of resistance to imatinib mesylate in vitro and in clinical situations, their relative significance and contributions remain poorly understood, as is the sequence of events leading to the selection of the resistant phen...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20131

    authors: Scappini B,Gatto S,Onida F,Ricci C,Divoky V,Wierda WG,Andreeff M,Dong L,Hayes K,Verstovsek S,Kantarjian HM,Beran M

    更新日期:2004-04-01 00:00:00

  • Mantle-zone lymphoma: a follicular variant of intermediate lymphocytic lymphoma.

    abstract::A clinicopathologic analysis of 12 cases of a morphologically distinctive non-Hodgkin's malignant lymphoma which appeared to arise from the mantle zones of secondary lymphoid follicles is presented. In lymph node and spleen sections, atypical small lymphoid cells with slightly irregular and indented nuclear contours p...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820401)49:7<1429::aid-cncr2820

    authors: Weisenburger DD,Kim H,Rappaport H

    更新日期:1982-04-01 00:00:00

  • DNA ploidy analysis of mucinous cystic tumors of the pancreas. Correlation of aneuploidy with malignancy and poor prognosis.

    abstract:BACKGROUND:Benign and malignant pancreatic mucinous tumors differ in proliferative activity, production of tumor markers, and expression of growth factors. DNA ploidy is a useful index of aggressiveness and poor survival in ductal adenocarcinoma, but has not been studied in pancreatic cystic tumors. METHODS:The DNA pl...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960101)77:1<58::AID-CNCR

    authors: Southern JF,Warshaw AL,Lewandrowski KB

    更新日期:1996-01-01 00:00:00

  • Carcinocythemia (carcinoma cell leukemia) due to metastatic carcinoma of the breast: report of a case.

    abstract::A patient with a 17-year course of metastatic lobular carcinoma of the breast is described who developed large numbers of circulating carcinoma cells which were easily detectable in several routine peripheral blood smears shortly before death. This rare complication of carcinoma has been called "carcinocythemia." Carc...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197712)40:6<3107::aid-cncr282040

    authors: Myerowitz RL,Edwards PA,Sartiano GP

    更新日期:1977-12-01 00:00:00

  • Adenoid cystic carcinoma of the head and neck: Incidence and survival trends based on 1973-2007 Surveillance, Epidemiology, and End Results data.

    abstract:BACKGROUND:Adenoid cystic carcinoma (ACC) of the head and neck (ACCHN) is a rare tumor of minor salivary, parotid, and submandibular glands. The biologic behavior of the disease is poorly understood, and nonsurgical treatment strategies have yet to be standardized. The long-term prognosis continues to be guarded, with ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27408

    authors: Ellington CL,Goodman M,Kono SA,Grist W,Wadsworth T,Chen AY,Owonikoko T,Ramalingam S,Shin DM,Khuri FR,Beitler JJ,Saba NF

    更新日期:2012-09-15 00:00:00

  • New diagnostic, staging, and therapeutic aspects of early breast cancer.

    abstract::Many advances have occurred in breast cancer through research and clinical trials. More confidence in new biological consumptions about invasive breast cancer indicate that: (1) details of the primary breast cancer do not control survival; (2) breast-only failures after local excision do not bias against survival; and...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19900201)65:3+<634::aid-cncr2820

    authors: Cady B

    更新日期:1990-02-01 00:00:00

  • The prognostic impact of cyclin dependent kinase inhibitors p21WAF1, p27Kip1, and p16INK4/MTS1 in adenocarcinomas of the uterine cervix: an immunohistochemical evaluation of expression patterns in population-based material from 142 patients with internati

    abstract:BACKGROUND:The authors assessed the prognostic significance of abnormal cyclin dependent kinase inhibitor (CDKI) expression in adenocarcinomas of the uterine cervix. METHODS:Population-based, archival material from patients with International Federation of Gynecology and Obstetrics (FIGO) Stage I and II cervical adeno...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11727

    authors: Alfsen GC,Reed W,Sandstad B,Kristensen GB,Abeler VM

    更新日期:2003-11-01 00:00:00

  • Fine-needle aspiration of chromophobe renal cell carcinoma. Analysis of six cases.

    abstract:BACKGROUND:The chromophobe variant of renal cell carcinoma is a recently described and frequently unrecognized tumor. Because the prognosis of the chromophobe variant appears to be intermediate between that of oncocytoma and the clear cell variant of renal cell carcinoma, accurate diagnosis may be important for appropr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19970425)81:2<122::aid-cnc

    authors: Granter SR,Renshaw AA

    更新日期:1997-04-25 00:00:00

  • Intensive sequential chemotherapy with hematopoietic growth factor support for non-Hodgkin lymphoma in patients infected with the human immunodeficiency virus.

    abstract:BACKGROUND:Optimal treatment of human immunodeficiency virus (HIV)-associated non-Hodgkin lymphoma (NHL) has yet to be defined, because chemotherapy could exacerbate immunodeficiency, with subsequent adverse effects for patients. METHODS:The authors investigated the feasibility of an intensive chemotherapy regimen for...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/cncr.20019

    authors: Costello RT,Zerazhi H,Charbonnier A,de Colella JM,Alzieu C,Poizot-Martin I,Cohen R,Bardou VJ,Xerri L,Olive D,Nezri M,Lepeu G,Gastaut JA

    更新日期:2004-02-15 00:00:00

  • Ductal carcinoma in situ of the male breast.

    abstract:BACKGROUND:Ductal carcinoma in situ (DCIS) of the male breast is an uncommon disease, accounting for approximately 7% of all male breast carcinomas. Compared with invasive carcinomas of the breast, the prognosis associated with DCIS in men is excellent; however, clinical features, pathology, and treatment of this disea...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19940815)74:4<1289::aid-cncr2820

    authors: Camus MG,Joshi MG,Mackarem G,Lee AK,Rossi RL,Munson JL,Buyske J,Barbarisi LJ,Sanders LE,Hughes KS

    更新日期:1994-08-15 00:00:00

  • Tumor infiltrating Foxp3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients.

    abstract:BACKGROUND:Early stage lung cancer has a variable prognosis, and there are currently no markers that predict which patients will recur. This study examined the relation between tumor-regulatory T (Treg) cells and total tumor-infiltrating T-cell lymphocytes (TIL) to determine whether they correlated with recurrence. ME...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22282

    authors: Petersen RP,Campa MJ,Sperlazza J,Conlon D,Joshi MB,Harpole DH Jr,Patz EF Jr

    更新日期:2006-12-15 00:00:00

  • Facilitating clinical trials. The expanding role of the nurse.

    abstract::Clinical trials are becoming increasingly difficult to carry out in the face of a changing health care delivery system. The reluctance of third party payers to reimburse for experimental therapy and the growing practice of providers to limit resources allocated for the care of cancer patients undergoing such therapies...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.2820671818

    authors: Engelking C

    更新日期:1991-03-15 00:00:00