Abstract:
:High tissue concentrations of human chorionic gonadotropin (hCG) and alpha-fetoprotein (AFP) were revealed by radioimmunoassay in a hepatic tumor which was surgically removed from a two-year, eight-month-old boy manifesting sexual precocity. Histologically the tumor showed an embryonal type hepatoblastoma admixed with multinucleated tumor giant cells. The localization of native hCG and hCG-beta subunit was immunohistochemically demonstrated in some of the above giant cells, while that of alpha-fetoprotein was diffusely in the tumor cells of hepatoblastoma of embryonal type. Ultrastructural features of the giant cells were also presented.
journal_name
Cancerjournal_title
Cancerauthors
Morinaga S,Yamaguchi M,Watanabe I,Kasai M,Ojima M,Sasano Ndoi
10.1002/1097-0142(19830501)51:9<1647::aid-cncr2820subject
Has Abstractpub_date
1983-05-01 00:00:00pages
1647-52issue
9eissn
0008-543Xissn
1097-0142journal_volume
51pub_type
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