Evaluation of size in prognosis of oral cancer.

abstract：BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...

journal_title：Cancer

authors： Wallace SR,Oken MM,Lunetta KL,Panoskaltsis-Mortari A,Masellis AM

更新日期：2001-04-01 00:00:00

abstract：:Forty-nine patients with regionally confined recurrent malignancy were treated with intra-arterial cis-diamminedichloro platinum II in a Phase I-II trial. A safe starting dose of 120 mg/m2 was established. An overall response rate of 45% was noted with significant responses observed among patients with melanoma, sarco...

journal_title：Cancer

authors： Calvo DB 3rd,Patt YZ,Wallace S,Chuang VP,Benjamin RS,Pritchard JD,Hersh EM,Bodey GP Sr,Mavligit GM

更新日期：1980-03-15 00:00:00

abstract：:In 79 cases of histologically verified anaplastic giant-cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy-eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an add...

journal_title：Cancer

authors： Jereb B,Stjernswärd J,Löwhagen T

更新日期：1975-05-01 00:00:00

abstract：:This study examines the interrelationships of depth of penetration, tumor size, and the number of positive nodes in Dukes C colorectal cancer. The results indicated that depth of tumor penetration was related to both tumor size and the number of positive regional lymph nodes. Tumors with positive nodes which failed to...

journal_title：Cancer

authors： Wolmark N,Fisher ER,Wieand HS,Fisher B

更新日期：1984-06-15 00:00:00

abstract：BACKGROUND:Despite the widespread use of Papanicolaou (Pap) smear screening, substantial morbidity and mortality from cervical carcinoma continue in the U.S. Although access to screening is a major barrier to use of the Pap smear, invasive cervical carcinoma (ICC) still is observed in health plan members who have compr...

journal_title：Cancer

authors： Sung HY,Kearney KA,Miller M,Kinney W,Sawaya GF,Hiatt RA

更新日期：2000-05-15 00:00:00

abstract：BACKGROUND:The results of an international, multicenter, randomized, double-blind, controlled study assessing the efficacy and safety of lenalidomide treatment in patients with refractory stage IV metastatic malignant melanoma are reported. METHODS:The study compared treatment with lenalidomide (25 mg/d on Days 1-21 o...

journal_title：Cancer

authors： Eisen T,Trefzer U,Hamilton A,Hersey P,Millward M,Knight RD,Jungnelius JU,Glaspy J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Ultrasonography has a limited value in endometrial assessment for identification of endometrial pathologies in postmenopausal tamoxifen-treated patients. METHODS:We compared the rate of endometrial pathologies and the mean +/- SD of endometrial thickness diagnosed after the first and second transvaginal ult...

journal_title：Cancer

authors： Cohen I,Azaria R,Shapira J,Yigael D,Tepper R

更新日期：2002-06-15 00:00:00

abstract：:Two children with cancer that persisted after multiple exploratory laparotomies, external beam radiation therapy, and multidrug chemotherapy had gold 198 (198Au) seeds implanted into their localized but unresectable tumor. Both children are alive, are receiving no therapy, and are disease-free more than 2 years later....

journal_title：Cancer

authors： Knight PJ,Doornbos JF,Rosen D,Lin JJ,Farha GJ

更新日期：1986-03-01 00:00:00

abstract：:The case of hepatocellular carcinoma (HCC) with foci of hepatoblastoma in a 7-year-old boy, the son of a hepatitis B surface antigen (HBsAg) carrier mother, is described. Twelve other malignant liver tumors in children were tumors in children were also reviewed for HBsAg and hepatitis B core antigen (HBcAg). Both were...

journal_title：Cancer

authors： De Potter CR,Robberecht E,Laureys G,Cuvelier CA

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:This study was performed to develop a sensitive method for the detection of circulating hepatocellular carcinoma (HCC) cells in peripheral blood, in advance of the diagnosis of distant metastasis of HCC by conventional means. METHODS:Peripheral blood (5 ml) samples were obtained from 64 patients with HCC an...

journal_title：Cancer

authors： Komeda T,Fukuda Y,Sando T,Kita R,Furukawa M,Nishida N,Amenomori M,Nakao K

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Although axillary lymph node metastasis is one of the most important prognostic determinants of breast carcinoma prognoses, the reasons why tumors vary in their capability to produce for axillary metastases remain unclear. METHODS:The authors used data from the nationwide Patient Care Evaluation (PCE) surve...

journal_title：Cancer

authors： Gann PH,Colilla SA,Gapstur SM,Winchester DJ,Winchester DP

更新日期：1999-10-15 00:00:00

abstract：BACKGROUND:Nodal status is one of the most important prognostic factors for distal bile duct cancer. The pattern of lymphatic spread of distal bile duct cancer was analyzed by determining the frequency of involvement of various lymph nodes. MATERIALS AND METHODS:From 1973 to 1991, 29 patients with distal bile duct can...

journal_title：Cancer

authors： Kayahara M,Nagakawa T,Ueno K,Ohta T,Takeda T,Miyazaki I

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Intraabdominal desmoplastic small cell tumor is a rare malignancy that has only recently been described. In the adult population, it is usually seen in young males. The tumor appears to arise as a dominant mass or masses in the abdominal cavity, particularly in the pelvic region, without a clear visceral ori...

journal_title：Cancer

authors： Amato RJ,Ellerhorst JA,Ayala AG

更新日期：1996-08-15 00:00:00

abstract：:The clinical features and laboratory results of 63 patients with or at risk for AIDS with lymphoid neoplasias seen from November 1980 through November 1986 are reviewed. Forty-three had systemic non-Hodgkin's lymphoma (NHL), nine had primary large cell lymphomas of the brain, 11 had Hodgkin's disease (HD), and one had...

journal_title：Cancer

authors： Lowenthal DA,Straus DJ,Campbell SW,Gold JW,Clarkson BD,Koziner B

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Cancer survivors face psychosocial issues that increase their risk of suicide. This study examined the risk of suicide across cancer sites, with a focus on survivors of head and neck cancer (HNC). METHODS:The Surveillance, Epidemiology, and End Results 18-registry database (from 2000 to 2014) was queried fo...

journal_title：Cancer

authors： Osazuwa-Peters N,Simpson MC,Zhao L,Boakye EA,Olomukoro SI,Deshields T,Loux TM,Varvares MA,Schootman M

更新日期：2018-10-15 00:00:00

abstract：:Stage IV-S neuroblastoma is a unique disseminated neoplasia characterized by remote disease to the liver, skin, or bone marrow. Stage IV-S patients have frequent spontaneous remissions and a 60% to 90% survival rate. Many investigators have recommended minimal or no therapeutic intervention; however, some patients do ...

journal_title：Cancer

authors： Stephenson SR,Cook BA,Mease AD,Ruymann FB

更新日期：1986-07-15 00:00:00

abstract：:From 1954 through 1982, 57 patients with invasive, distal rectal cancer had a full-thickness local excision with curative intent. Prognostic criteria and need for further treatment were based on the histopathologic results of the operative specimen. The overall 5-year survival rate was 83.4%. The rectal cancer-specifi...

journal_title：Cancer

authors： DeCosse JJ,Wong RJ,Quan SH,Friedman NB,Sternberg SS

更新日期：1989-01-15 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographic locations. In the current study, neoplasms from two separate geographic regions were analyzed for the presence of HPV DNA: METHODS:One hundred and ten esoph...

journal_title：Cancer

authors： Suzuk L,Noffsinger AE,Hui YZ,Fenoglio-Preiser CM

更新日期：1996-08-15 00:00:00

abstract：BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

journal_title：Cancer

authors： Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

更新日期：2002-05-15 00:00:00

abstract：:Adrenal cortical carcinoma is an uncommon neoplasm in children. Only a handful of congenital adrenal cortical carcinoma cases have been described. A newborn who had metastatic adrenal cortical carcinoma (skin metastases and cerebral lesions) is described. This patient underwent surgical resection of the right adrenal ...

journal_title：Cancer

authors： Saracco S,Abramowsky C,Taylor S,Silverman RA,Berman BW

更新日期：1988-08-01 00:00:00

abstract：:A search of the records of 10 pediatric oncology centers revealed 102 children with more than one malignant neoplasm. In this group of 102 patients, all pediatric cancers were seen as initial lesions, but Wilms' tumor and retinoblastoma were over-represented and leukemia and brain tumors underrepresented. Survival var...

journal_title：Cancer

authors： Meadows AT,D'Angio GJ,Miké V,Banfi A,Harris C,Jenkin RD,Schwartz A

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Cell kinetics studies performed with immunohistochemical techniques to estimate the S-phase fraction have elucidated the proliferative potential of individual brain tumors. METHODS:The authors developed a new double-labeling method that enables other cell kinetics variables, including the duration of the S-...

journal_title：Cancer

authors： Shibuya M,Ito S,Davis RL,Wilson CB,Hoshino T

更新日期：1993-05-15 00:00:00

abstract：:Data are presented on mortality from neoplasms as determined from death certificates in a cohort of 8393 college men, according to athletic status in college. Major athletes (lettermen) died significantly more often from neoplasms than nonathletes. Mean age at death from neoplasms (underlying cause) was significantly ...

journal_title：Cancer

authors： Polednak AP

更新日期：1976-07-01 00:00:00

abstract：:Since single drug therapy of chronic lymphocytic leukemia (CLL) has not resulted in prolonged remissions of advanced disease, we initiated a program of combination chemotherapy, COP (cycloposphamide, vincristine sulfate, prednisone) for CLL patients with increasing adenopathy, spenomegaly, and/or signs of marrow failu...

journal_title：Cancer

authors： Liepman M,Votaw ML

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:This study was undertaken to determine whether the use of intermediate dose methotrexate in combination with vinblastine, doxorubicin, and cisplatin as first-line therapy increases the proportion of major responders and overall survival in patients with unresectable or metastatic transitional cell carcinoma ...

journal_title：Cancer

authors： Dodd PM,McCaffrey JA,Mazumdar M,Scher H,Vlamis V,Higgins G,Herr H,Bajorin DF

更新日期：1999-03-01 00:00:00

abstract：:Fourteen patients with advanced salivary gland malignancies were treated with combination chemotherapy. Five of 13 patients responded to cyclophosphamide and adriamycin and two patients in the responding groups underwent further potentially curable treatment, rendering them disease-free. Three patients with mucoepider...

journal_title：Cancer

authors： Posner MR,Ervin TJ,Weichselbaum RR,Fabian RL,Miller D

更新日期：1982-12-01 00:00:00

abstract：:A familial cancer aggregation comprising sarcomas, brain tumors, leukemias, and carcinomas of breast, larynx, lung, adrenal, cortex, and other sites has been studied from a pathologic--genetic standpoint. Based upon sibships segregating for cancer, the genetic segregation parameter is estimated to be 45.6 +/- 11% whi...

journal_title：Cancer

authors： Lynch HT,Mulcahy GM,Harris RE,Guirgis HA,Lynch JF

更新日期：1978-05-01 00:00:00

abstract：:The activity of the alpha interferons against AIDS-related Kaposi's sarcoma (KS) has been demonstrated in numerous clinical trials. Unfortunately, most reports have involved small patient cohorts and a variety of dosages and schedules of administration. We report here a series of Phase II trials with interferon alfa-2...

journal_title：Cancer

authors： Volberding PA,Mitsuyasu RT,Golando JP,Spiegel RJ

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori recently was identified as a risk factor for gastric cancer. Its association with preneoplastic conditions of the stomach, however, is undocumented. METHODS:Gastric biopsy specimens from 245 symptomatic patients were examined for neoplastic and preneoplastic lesions and for gastric H. py...

journal_title：Cancer

authors： Guarner J,Mohar A,Parsonnet J,Halperin D

更新日期：1993-01-15 00:00:00

abstract：BACKGROUND:This study was conducted to investigate the influence of therapeutic parameters on local control (LC) in the sphincter-conserving treatment of T2-T3 anal carcinoma. METHODS:From 1976 to 1993, 137 patients with anal carcinoma classified as T2 (85 patients) or T3 (52 patients) were treated curatively by radio...

journal_title：Cancer

authors： Allal AS,Mermillod B,Roth AD,Marti MC,Kurtz JM

更新日期：1997-06-15 00:00:00