Abstract:
:Stage IV-S neuroblastoma is a unique disseminated neoplasia characterized by remote disease to the liver, skin, or bone marrow. Stage IV-S patients have frequent spontaneous remissions and a 60% to 90% survival rate. Many investigators have recommended minimal or no therapeutic intervention; however, some patients do experience progressive disease and ultimately die of neuroblastoma. Many authors have commented on single prognostic factors such as age and site of metastatic involvement. Five newborns were recently seen at Walter Reed Army Medical Center with Stage IV-S neuroblastoma. Four of these children died of mechanical complications associated with massive hepatomegaly, prompting this review of Stage IV-S neuroblastoma to determine prognostic factors.
journal_name
Cancerjournal_title
Cancerauthors
Stephenson SR,Cook BA,Mease AD,Ruymann FBdoi
10.1002/1097-0142(19860715)58:2<372::aid-cncr28205subject
Has Abstractpub_date
1986-07-15 00:00:00pages
372-5issue
2eissn
0008-543Xissn
1097-0142journal_volume
58pub_type
杂志文章相关文献
CANCER文献大全abstract::Recent follow-up studies of patients with mammary carcinoma treated with breast-conserving primary radiotherapy identified a triad of pathologic features significantly associated with local treatment failure. These unfavorable characteristics of the primary tumor were: poor or undifferentiated nuclear grade; intraduct...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860401)57:7<1415::aid-cncr2820
更新日期:1986-04-01 00:00:00
abstract:BACKGROUND:Increased soluble human epidermal growth factor receptor 2 (sHER2) is an indicator of a poor prognosis in HER2-positive metastatic breast cancer. In this study, the authors evaluated levels of sHER2 during treatment and at the time of disease recurrence in the adjuvant North Central Cancer Treatment Group N9...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.28130
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Cervical carcinoma remains a significant health risk for the older woman. In the current study the yield of screening of mature women in an established, opportunistic screening program was examined. Strategies for improving screening in this age group were identified through examination of recent Pap test hi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10723
更新日期:2002-08-25 00:00:00
abstract::Various dose-time treatment plans have been used to obtain long duration pain relief in patients with metastatic bone disease. Very little has appeared in the literature evaluating the relationship of dose and fractionation to initial, delayed and permanent bone pain relief. At the Swedish Hospital Tumor Institute, 15...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197602)37:2<984::aid-cncr2820370
更新日期:1976-02-01 00:00:00
abstract::Apart from choriocarcinoma, involvement of the central nervous system (CNS) by gynecologic malignancy is rare. A 10-year retrospective review at the University of Washington Medical Center (Seattle, WA) and Swedish Hospital and Medical Center Tumor Registry (Seattle, WA) identified 14 patients with cerebral metastases...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910415)67:8<2194::aid-cncr2820
更新日期:1991-04-15 00:00:00
abstract::Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluor...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<1836::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract:BACKGROUND:Plasma acidic glutathione S-transferase (GST-pi) concentrations in 135 patients with gastrointestinal cancer were measured by an improved radioimmunoassay (RIA). METHODS:Blood was collected into a silicified glass tube containing a specific anticoagulant. The plasma, which was separated rapidly by centrifug...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19951015)76:8<1363::aid-cncr2820
更新日期:1995-10-15 00:00:00
abstract::During the period from March 1963 through March 1978, 30 patients with malignant neoplasms of the paranasal sinuses were treated with supervoltage technique at the University of Rochester Medical Center. Twenty-one patients had at least the medial portion of the orbit within the effective treatment volume and the rest...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19830315)51:6<980::aid-cncr28205
更新日期:1983-03-15 00:00:00
abstract:BACKGROUND:Cisplatin is one of the single drugs that has shown the best documented effect in treating patients with locally recurrent or metastatic urothelial cancer. To the authors' knowledge, the effect of the combination of different platinum analogues in treating transitional cell carcinoma has not been evaluated p...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19951115)76:10<1797::aid-cncr282
更新日期:1995-11-15 00:00:00
abstract:BACKGROUND:Overall survival (OS) is considered the gold standard for determining treatment efficacy in oncology trials, but the relation between treatment and OS can be challenging to assess because of long study durations and the impact of subsequent therapies on outcome. Using OS can be particularly difficult for new...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30622
更新日期:2017-05-15 00:00:00
abstract::A series of 273 unselected patients with bronchial carcinoma, comprising a total prospective 5-year study from a Swedish county with an observed 5-year survival of 7.0%, is presented. The autopsy rate in deceased patients was 94%. All diagnoses were histologically or cytologically verified. The 5-year survival rates f...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840515)53:10<2211::aid-cncr282
更新日期:1984-05-15 00:00:00
abstract::Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the two regimens. Comb...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197511)36:5<1589::aid-cncr282036
更新日期:1975-11-01 00:00:00
abstract:BACKGROUND:The current analysis of outcomes in a large series of adult patients with intracranial ependymal tumors contributes to the characterization of the primary prognostic factors and to the therapeutic management of this rare disease, for which limited information is available in the literature. METHODS:The auth...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.20074
更新日期:2004-03-15 00:00:00
abstract:BACKGROUND:Recent clinical trials support adding ovarian suppression (OS) to oral endocrine therapy (ET) for premenopausal women with early breast cancer. The adoption of OS among real-world populations and the impact of OS on ET adherence have not been evaluated. METHODS:This study examined a retrospective, observati...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33367
更新日期:2021-01-28 00:00:00
abstract:BACKGROUND:Peritoneal metastases are one reason for the poor prognosis of scirrhous gastric cancer. However, the mechanism of peritoneal metastasis remains unclear. We therefore investigated the interaction between gastric cancer cells and peritoneal fibroblasts, in vivo and in vitro. METHODS:A human scirrhous gastric...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960415)77:8<1668::AID-CN
更新日期:1996-04-15 00:00:00
abstract:BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33075
更新日期:2020-09-15 00:00:00
abstract::A collaborative study of the humoral and cellular immune status of patients with carcinoma of the Head and Neck (H&N) was conducted at the West Virginia University (WVU) hospital. In addition, blind-coded serum panels were supplied on H&N cancer patients being treated at the National Cancer Institute (NCI). Serum prot...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860615)57:12<2295::aid-cncr282
更新日期:1986-06-15 00:00:00
abstract::Fifty-three patients with advanced lymphocytic lymphoma were randomly assigned to treatment with the combination cyclophosphamide, vincristine, and prednisone (CVP) or the same agents used successively in maximal doses (C-V-P). Complete remissions occurred in 68% with CVP and 48% with C-V-P. For patients with nodular ...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(197801)41:1<23::aid-cncr28204101
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:Patients with advanced cancer often experience fatigue and other symptoms that negatively impact their quality of life. The current trial investigated the effect of melatonin on fatigue and other symptoms in patients with advanced cancer. METHODS:Patients who were aged ≥18 years, had a histologically confir...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.29563
更新日期:2015-10-15 00:00:00
abstract:BACKGROUND:Thalidomide is an antiangiogenic agent with immune modulating potential. The objective of this study was to determine response rates among women who were treated for recurrent ovarian cancer using topotecan with or without thalidomide. METHODS:Women were enrolled in this multicenter, prospective, randomized...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.23164
更新日期:2008-01-15 00:00:00
abstract:BACKGROUND:Outcomes have improved significantly in multiple myeloma (MM), but racial disparities in health care access and survival exist. A comprehensive analysis exploring MM care and racial disparities is warranted. METHODS:Patients with MM from 1991 to 2010 in the Surveillance, Epidemiology, and End Results-Medica...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31237
更新日期:2018-04-15 00:00:00
abstract:BACKGROUND:Abnormalities in chromosome 11q13 regions have been frequently found in head and neck squamous carcinoma. Recent studies indicate that the PRAD-1 (also CCND1), which encodes cyclin D1, is a putative oncogene that is an important component of this region. METHODS:DNA was extracted from 32 snap-frozen specime...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940701)74:1<152::aid-cncr28207
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:The presence of urinary excretion products of human chorionic gonadotropin (hCG) has been proposed as a tumor marker. To ascertain the clinical value in gynecologic cancers, the authors studied 612 nonpregnant women. METHODS:Three different assays in four clinical groups were compared: no disease, benign di...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930615)71:12<4124::aid-cncr282
更新日期:1993-06-15 00:00:00
abstract:BACKGROUND:The histogenesis of carcinosarcoma is still unknown. METHODS:A new human uterine cell line, EMTOKA, derived from a carcinosarcoma of the uterus, has been passed successfully in cell culture for more than 2 years. The cell line was established on April 11, 1989, in a uterine tumor of a 64-year-old Japanese w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930201)71:3<775::aid-cncr28207
更新日期:1993-02-01 00:00:00
abstract::Twenty of 391 newly diagnosed cases of prostatic cancer (5%) had a prior prostatectomy for benign disease. Digital rectal examination in 16 of 19 patients (84%) revealed a significant prostatic abnormality. Continued serial digital rectal examination should be performed routinely after prostatectomy for benign disease...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860815)58:4<994::aid-cncr28205
更新日期:1986-08-15 00:00:00
abstract:BACKGROUND:Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The Univ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31112
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Expression of neuroectodermal markers is a key feature of small cell lung carcinoma (SCLC). Although immune responses against a number of these proteins have been associated with paraneoplastic neuronal disease (PND), most patients with SCLC have anti-neuroectodermal antibodies in the absence of PND. Whether...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21088
更新日期:2005-06-15 00:00:00
abstract::This survey of the incidence of melanoma in New South Wales, Australia, from 1970 to 1976 revealed a doubling of incidence in the seven year period. The most marked rise occurred in 1972. A marked preponderance of leg melanoma in women and trunk melanoma in men was noted. The incidence of melanoma in men continues to ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800715)46:2<427::aid-cncr28204
更新日期:1980-07-15 00:00:00
abstract::Racial differences in the risk of cancer of the urinary bladder associated with cigarette smoking and alcohol consumption were examined in a study of 1663 cases (1534 whites and 129 blacks) and 4930 controls matched 3:1 by sex, race, and age to the cases. Significant increases in cancer risk associated with cigarette ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19901215)66:12<2673::aid-cncr282
更新日期:1990-12-15 00:00:00
abstract:BACKGROUND:The first analysis of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial (median follow-up, 33 months) demonstrated that in adjuvant endocrine therapy for postmenopausal patients with early-stage breast cancer, anastrozole was superior to tamoxifen in terms of disease-free survival (DFS), time to r...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/cncr.11745
更新日期:2003-11-01 00:00:00