Adherence to endocrine therapy including ovarian suppression: A large observational cohort study of US women with early breast cancer.

abstract：:A 55-year-old man is reported who initially developed chronic lymphocytic leukemia. Seven years later, after chemotherapy with chlorambucil, chronic myelogenous leukemia was diagnosed in addition to the chronic lymphocytic leukemia. Four previously reported cases with the same sequence of events are reviewed as well a...

journal_title：Cancer

authors： Schreiber ZA,Axelrod MR,Abebe LS

更新日期：1984-08-15 00:00:00

abstract：:The expression of the Thomsen-Friedenreich antigen (T-antigen) in normal and neoplastic urothelium was investigated using paraffin-processed and fresh frozen tissue sections obtained by biopsy from 56 patients. The T-antigen was detected through its binding to the peanut agglutinin (PNA) with two methods: a biotin-avi...

journal_title：Cancer

authors： Limas C,Lange P

更新日期：1986-09-15 00:00:00

abstract：:Between September 1976 and May 1980, 135 patients with operable breast cancer and positive axillary nodes received l-phenylalanine mustard, adjunct to surgery, 0.15 mg/kg for five days, six weekly, and were randomised prospectively to levamisole 150 mg for three days, two weekly, or a placebo. Treatment was continued ...

journal_title：Cancer

authors： Kay RG,Mason BH,Stephens EJ,Arthur JF,Hitchcock GC,Trindall PL,Rodgers R,Mullins P

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:In the current study, the authors attempted to describe the incidence, most common sites, and mortality of second primary malignancies among survivors of common cancers. METHODS:The authors identified patients aged ≥18 years who were diagnosed with a primary malignancy from the 10 most common cancer sites (...

journal_title：Cancer

authors： Donin N,Filson C,Drakaki A,Tan HJ,Castillo A,Kwan L,Litwin M,Chamie K

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Obesity is a well known risk factor for the development of endometrial cancer; however, weight alone does not account for all cases. The authors hypothesized that insulin resistance also contributes to an increased risk for endometrial cancer. Adiponectin is a protein secreted by adipose cells and has been s...

journal_title：Cancer

authors： Soliman PT,Wu D,Tortolero-Luna G,Schmeler KM,Slomovitz BM,Bray MS,Gershenson DM,Lu KH

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Primary lymphomas of the uterus or cervix are so rare that treatment series of single institutions consist of very small numbers of patients, making standard treatment difficult to define. The outcome of patients treated with a combination of chemotherapy and radiation therapy was analyzed for all but patien...

journal_title：Cancer

authors： Stroh EL,Besa PC,Cox JD,Fuller LM,Cabanillas FF

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Recurrent central neurocytoma is very rare and to the authors' knowledge data regarding its response to chemotherapy currently are not available. METHODS:Three patients with progressive neurocytoma received chemotherapy after their informed consent was obtained. Disease recurred in two patients after surger...

journal_title：Cancer

authors： Brandes AA,Amistà P,Gardiman M,Volpin L,Danieli D,Guglielmi B,Carollo C,Pinna G,Turazzi S,Monfardini S

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Myoepithelial carcinoma, also know as malignant myoepithelioma, is rare in the salivary gland, and its cytologic features have rarely been reported. DESIGN:Four cases of myoepithelial carcinoma with cytology were retrieved from the archives of the Pathology Departments of two academic institutes. In three c...

journal_title：Cancer

authors： Chhieng DC,Paulino AF

更新日期：2002-02-25 00:00:00

abstract：BACKGROUND:The mortality of patients with colorectal carcinoma depends mainly upon subsequent liver metastasis even after curative operation. However, it is very difficult to predict the incidence of liver metastasis by analyzing conventional tumor markers or pathologic findings. In the current study, the authors exami...

journal_title：Cancer

authors： Kato M,Ito Y,Kobayashi S,Isono K

更新日期：1996-04-15 00:00:00

abstract：BACKGROUND:The assessment of pancreatic ductal adenocarcinoma (PDAC) response to therapy remains challenging. The objective of this study was to investigate whether changes in the tumor/parenchyma interface are associated with response. METHODS:Computed tomography (CT) scans before and after therapy were reviewed in 4...

journal_title：Cancer

authors： Amer AM,Zaid M,Chaudhury B,Elganainy D,Lee Y,Wilke CT,Cloyd J,Wang H,Maitra A,Wolff RA,Varadhachary G,Overman MJ,Lee JE,Fleming JB,Tzeng CW,Katz MH,Holliday EB,Krishnan S,Minsky BD,Herman JM,Taniguchi CM,Das P,

更新日期：2018-04-15 00:00:00

abstract：:Although weight loss has an adverse impact on cancer patient survival, the ability of caloric provision via total parenteral nutrition (TPN) to favorably influence outcome in chemotherapy-treated populations is not established. In randomized trials, no significant improvement in either response or survival was associa...

journal_title：Cancer

authors： Chlebowski RT

更新日期：1985-01-01 00:00:00

abstract：:Nuclear DNA content of paraffin-embedded tissue from 48 adrenocortical neoplasms, 18 histologically normal control adrenal glands, and five hyperplastic adrenal glands was analyzed retrospectively using flow cytometry. Aneuploidy was compared with morphologic criteria as a predictor of recurrence. All 18 controls, fiv...

journal_title：Cancer

authors： Amberson JB,Vaughan ED Jr,Gray GF,Naus GJ

更新日期：1987-06-15 00:00:00

abstract：:Based on laboratory studies showing enhanced cytotoxicity of floxuridine (FUDR) when used with high doses of leucovorin (LV), a pilot study of FUDR and LV through an implantable pump was initiated for the treatment of hepatic metastases from colorectal cancer. The highest dose of LV that could be administered, taking ...

journal_title：Cancer

authors： Kemeny N,Cohen A,Bertino JR,Sigurdson ER,Botet J,Oderman P

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the racial and ethnic disparities in outcomes and their association with process-of-care measures for elderly Medicare recipients with localized prostate cancer. METHODS:The Surveillance, Epidemiology, and End Results-Medicare databases for the period from 1995 to 2...

journal_title：Cancer

authors： Jayadevappa R,Chhatre S,Johnson JC,Malkowicz SB

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Adult T-cell leukemia/lymphoma (ATLL) is a neoplasm of the mature helper T-lymphocyte. Human T-lymphotropic virus type 1 (HTLV-1) has been shown to be the cause of this neoplasm. Recently, however, the HTLV-1 genome has been found in some patients with cutaneous T-cell lymphoma (CTCL), which suggests a causa...

journal_title：Cancer

authors： Kikuchi A,Ohata Y,Matsumoto H,Sugiura M,Nishikawa T

更新日期：1997-01-15 00:00:00

abstract：BACKGROUND:Strong correlations have been reported between expression of urokinase-type plasminogen activator (uPA) and poor prognosis in several human carcinomas. The clinical significance of secreted levels of uPA, its receptor (uPAR), and its inhibitors (PAI-1 and PAI-2) in the ascites of patients with epithelial ova...

journal_title：Cancer

authors： Chambers SK,Gertz RE Jr,Ivins CM,Kacinski BM

更新日期：1995-04-01 00:00:00

abstract：:A 26-month-old boy with Stage III abdominal ganglioneuroblastoma had tachycardia and hypertension. The hypertension increased following the institution of chemotherapy and necessitated the use of both alpha and beta adrenergic blocking agents to control the effects of the marked catecholamine production. After excisio...

journal_title：Cancer

authors： Kedar A,Glassman M,Voorhess ML,Fisher J,Allen J,Jenis E,Freeman AI

更新日期：1981-04-15 00:00:00

abstract：:Fourteen patients with 16 metastatic ostogenic sarcoma lesions were treated with high-dose methotrexate (HDMTX) with citrovorum factor rescue (CFR), adriamycin, and pulse high-dose cyclophosphamide combined with radiation therapy. Thirteen of 16 lesions responded. Responses consisted of relief of pain (6/6 patients) i...

journal_title：Cancer

authors： Rosen G,Tefft M,Martinez A,Cham W,Murphy ML

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Cancer and its treatment lead to increased financial distress for patients. To the authors' knowledge, to date, no standardized patient-reported outcome measure has been validated to assess this distress. METHODS:Patients with AJCC Stage IV solid tumors receiving chemotherapy for at least 2 months were recr...

journal_title：Cancer

authors： de Souza JA,Yap BJ,Wroblewski K,Blinder V,Araújo FS,Hlubocky FJ,Nicholas LH,O'Connor JM,Brockstein B,Ratain MJ,Daugherty CK,Cella D

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:DFP-10917, a deoxycytidine nucleoside analogue, has a unique mechanism of action resulting in leukemic cell death when administered for prolonged periods at low doses. The current phase 1/2 study investigated the safety, maximum tolerated dose, and evidence of antileukemic activity for DFP-10917 administered...

journal_title：Cancer

authors： Kantarjian HM,Jabbour EJ,Garcia-Manero G,Kadia TM,DiNardo CD,Daver NG,Borthakur G,Jain N,Waukau JB,Kwari MI,Ravandi F,Anderson BD,Iizuka K,Jin C,Zhang C,Plunkett WK

更新日期：2019-05-15 00:00:00

abstract：BACKGROUND:The purine analogs pentostatin and cladribine have revolutionized the treatment of hairy cell leukemia (HCL) with overall responses in greater than 85% of patients and a median progression-free survival of up to 15 years. They continue to be effective at second- and even third-line therapy; however, alternat...

journal_title：Cancer

authors： Else M,Osuji N,Forconi F,Dearden C,Del Giudice I,Matutes E,Wotherspoon A,Lauria F,Catovsky D

更新日期：2007-11-15 00:00:00

abstract：BACKGROUND:Poor accrual to cancer clinical trials may contribute to the lower improvement in survival observed for adolescents and young adults (AYAs) (those aged 15-39 years) with cancer. This has been difficult to quantify without reliable mechanisms to link incident cases with study enrollments. Using unique resourc...

journal_title：Cancer

authors： Collins CL,Malvar J,Hamilton AS,Deapen DM,Freyer DR

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Telomeres are protective structures at the ends of linear chromosomes, regulated by a host of associated proteins. When telomeres become dysfunctional, genomic instability ensues. The vast majority of cells undergo apoptosis, although a rare cell may survive and become tumorigenic. METHODS:The authors used ...

journal_title：Cancer

authors： Prescott J,McGrath M,Lee IM,Buring JE,De Vivo I

更新日期：2010-09-15 00:00:00

abstract：:The altered expression of the human retinoblastoma (RB) gene has been demonstrated to play an important role in the pathogenesis of RB and other tumors. To determine whether the RB gene might be involved in the pathogenesis of human ovarian and endometrial cancer, DNA from 24 human ovarian tumors, 3 normal ovaries, 3 ...

journal_title：Cancer

authors： Sasano H,Comerford J,Silverberg SG,Garrett CT

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:Specific kinase activity of the proto-oncogene product pp60(c-src) is reported to be elevated in patients with carcinoma of the colon, and a novel cytoplasmic protein-tyrosine kinase, C-terminal Src kinase (Csk), has been found to inactivate the members of the Src family protein-tyrosine kinase. In this stud...

journal_title：Cancer

authors： Cam WR,Masaki T,Shiratori Y,Kato N,Ikenoue T,Okamoto M,Igarashi K,Sano T,Omata M

更新日期：2001-07-01 00:00:00

abstract：:A retrospective analysis of a series of 162 patients treated for isolated chest wall recurrence of breast cancer after mastectomy was undertaken. Cumulative survival, distant relapse-free survival, and freedom from local progression after 5 years from the diagnosis of recurrence were 34%, 28%, and 45% respectively. Fi...

journal_title：Cancer

authors： Magno L,Bignardi M,Micheletti E,Bardelli D,Plebani F

更新日期：1987-07-15 00:00:00

abstract：:Wolfe has suggested that the mammographic parenchymal patterns can be used to identify a group with high incidence of breast cancer. To evaluate this claim, mammograms of women with breast cancer that was detected at the University of Michigan Breast Cancer Detection Demonstration Project have been classified and comp...

journal_title：Cancer

authors： Threatt B,Norbeck JM,Ullman NS,Kummer R,Roselle P

更新日期：1980-05-15 00:00:00

abstract：:Individualization of treatment using judicious combinations of external and intracavitary irradiation remains the cornerstone of the radiation management of carcinoma of the cervix. The inherent propensity of this cancer to either confine itself to the pelvis or else spread in a systematic and predictable manner throu...

journal_title：Cancer

authors： Rotman M,John M,Boyce J

更新日期：1981-07-15 00:00:00

abstract：:Between January 1988 and June 1990, seven previously untreated patients with histologically confirmed and clinically staged IIIa invasive thymoma (IT) were enrolled in a prospective, single treatment arm study of neoadjuvant chemotherapy (NC) followed by surgery and postoperative radiation therapy (4600 to 6000 cGy). ...

journal_title：Cancer

authors： Macchiarini P,Chella A,Ducci F,Rossi B,Testi C,Bevilacqua G,Angeletti CA

更新日期：1991-08-15 00:00:00

abstract：:Assume that the benefit of screening for breast cancer with a combination of mammography and a clinical examination is measured by comparing the five-year survival rate of women detected by screening to the five-year survival rate of women surface clinically with breast cancer, e.g., to the survival rate of women repo...

journal_title：Cancer

authors： Shwartz M

更新日期：1980-08-15 00:00:00