Cytology of myoepithelial carcinoma of the salivary gland.

Abstract:

BACKGROUND:Myoepithelial carcinoma, also know as malignant myoepithelioma, is rare in the salivary gland, and its cytologic features have rarely been reported. DESIGN:Four cases of myoepithelial carcinoma with cytology were retrieved from the archives of the Pathology Departments of two academic institutes. In three cases, the specimens were obtained by fine needle aspiration biopsy (FNA); the remaining case was a bench aspiration performed on the surgically resected specimen at the time of intra-operative consultation. The cytologic features were reviewed and correlated with the histology. RESULTS:The four patients with myoepithelial carcinoma (two men and two women) ranged in age from 48 to 64 years. Three cases arose from the parotid gland, and the remaining case was a recurrent tumor in the minor salivary glands of the hard palate. The aspirates of two cases consisted of predominantly spindle cells, one predominantly epithelioid/plasmacytoid cells, and one with a mixture of both spindle and epithelioid/plasmacytoid cells. Cellular pleomorphism was noted in two cases and mitotic figures in three cases. Two cases were cytologically diagnosed as malignant spindle cell neoplasm, not otherwise specified. The FNA of the recurrent tumor was diagnosed as consistent with the previous malignancy. The remaining case was interpreted as a pleomorphic adenoma with atypia. CONCLUSIONS:The cytologic features of myoepithelial carcinoma are diverse and may lack overt features of malignancy. Pathologists should be aware of this entity when evaluating cytologic specimen of salivary gland mass.

journal_name

Cancer

journal_title

Cancer

authors

Chhieng DC,Paulino AF

subject

Has Abstract

pub_date

2002-02-25 00:00:00

pages

32-6

issue

1

eissn

0008-543X

issn

1097-0142

pii

10.1002/cncr.10314

journal_volume

96

pub_type

杂志文章

相关文献

CANCER文献大全
  • Association of allelic imbalance at locus D13S171 (BRCA2) and p53 alterations with tumor kinetics and chromosomal instability (aneuploidy) in nonsmall cell lung carcinoma.

    abstract:BACKGROUND:BRCA2 gene, located at chromosome 13q12.3, frequently is altered in familial types of cancer in which a "double-hit" inactivation model seems to occur. In contrast, in sporadic forms of cancer there is frequent absence of a second event (point mutations) suggesting that allelic imbalance at the BRCA2 locus m...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20001101)89:9<1933::aid-cncr9>3.

    authors: Gorgoulis VG,Kotsinas A,Zacharatos P,Mariatos G,Liloglou T,Tsoli E,Kokotas S,Fassoulas C,Field JK,Kittas C

    更新日期:2000-11-01 00:00:00

  • Prognostic factors for clinically localized prostate carcinoma: analysis of 938 patients irradiated in the prostate specific antigen era.

    abstract:BACKGROUND:Pretreatment serum prostate specific antigen (PSA) level is a powerful prognostic factor for clinically localized prostate carcinoma. The traditional prognostic factors, T classification and Gleason score, appear to have been relegated to a minor position. This study was conducted to evaluate the relative pr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Zagars GK,Pollack A,von Eschenbach AC

    更新日期:1997-04-01 00:00:00

  • The effects of surgical treatment on survival and local recurrence of cutaneous malignant melanoma.

    abstract::All patients with a diagnosis of cutaneous malignant melanoma (CMM) in Western Australia from 1980 to 1981 were observed for up to 6 years to determine vital status and to detect the development of local recurrences of the primary lesion. Approximately 35% of all patients had their tumors excised with surgical margins...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920115)69:2<421::aid-cncr28206

    authors: Heenan PJ,English DR,Holman CD,Armstrong BK

    更新日期:1992-01-15 00:00:00

  • Does transurethral resection of a clinically benign prostate gland increase the risk of developing clinical prostate cancer? A 10-year follow-up study.

    abstract:BACKGROUND:Theoretical considerations have raised the suspicion that transurethral resection of the prostate (TURP) may increase the risk of developing prostate cancer in clinically benign prostate glands. Previous studies have not shown an increased risk among men who had undergone TURP for benign prostatic hyperplasi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19941015)74:8<2347::aid-cncr2820

    authors: Hammarsten J,Andersson S,Holmén A,Högstedt B,Peeker R

    更新日期:1994-10-15 00:00:00

  • Papanicolaou smear sensitivity for the detection of adenocarcinoma of the cervix: a study of 49 cases.

    abstract:BACKGROUND:Papanicolaou smear sensitivity for cervical adenocarcinoma (CVCA) is not well established. Also uncertain are the relative contributions to falsely negative diagnoses of sampling, screening, and interpretive errors. METHODS:Papanicolaou smears were identified from all patients at our institutions with biops...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Krane JF,Granter SR,Trask CE,Hogan CL,Lee KR

    更新日期:2001-02-25 00:00:00

  • Gastric carcinoids. An immunohistochemical and clinicopathologic study of 104 patients.

    abstract:BACKGROUND:Gastric carcinoids are uncommon, and are unlike carcinoids at other gastrointestinal sites, clinically and pathologically. METHODS:The authors studied specimens from 104 patients with gastric carcinoid, with study emphasis being placed on pathologic features, immunohistochemistry, clinical associations, and...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19940415)73:8<2053::aid-cncr2820

    authors: Thomas RM,Baybick JH,Elsayed AM,Sobin LH

    更新日期:1994-04-15 00:00:00

  • Transient neurologic disturbances induced by high-dose methotrexate treatment.

    abstract::Temporary neurologic abnormalities were detected in 9 of 60 patients undergoing treatment with high-dose methotrexate and citrovorum factor rescue (MTX-CF) for osteosarcoma. The incidence of abnormalities and abnormalities themselves were more severe than previously reported. This was attributed to an increased dose a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850915)56:6<1356::aid-cncr2820

    authors: Jaffe N,Takaue Y,Anzai T,Robertson R

    更新日期:1985-09-15 00:00:00

  • Colorectal cancer stage at diagnosis by socioeconomic and urban/rural status in California, 1988-2000.

    abstract:BACKGROUND:Rural residence has been associated with increased risk of late stage cancer diagnosis, but it is unknown if this is related to lower socioeconomic status (SES) of rural residents or to other factors. This study examined the impacts of SES and urban/rural status on colorectal cancer (CRC) stage at diagnosis ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22016

    authors: Parikh-Patel A,Bates JH,Campleman S

    更新日期:2006-09-01 00:00:00

  • Radition therpay control of nine patients with malignant thymoma.

    abstract::Malignant thymoma is a relatively rare condition and a review of the literature reveals approximately 100 reported cases. Only a small percentage of these have been treated with megavoltage radiation therapy; therefore, it is difficult to find the necessary information to establish a proper time-dose relationship for ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197801)41:1<117::aid-cncr2820410

    authors: Marks RD Jr,Wallace KM,Pettit HS

    更新日期:1978-01-01 00:00:00

  • A prospective postoperative evaluation of urinary tumor-associated antigens in sarcoma patients. Correlation with disease recurrence.

    abstract::Tumor-associated antigens (TAA) excreted into the urine of sarcoma patients can be detected by the complement-fixation assay. The authors prospectively measured TAA levels in the urine of 50 sarcoma patients postoperatively to determine whether reappearance of antigen in the urine would be predictive of disease recurr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840315)53:6<1306::aid-cncr2820

    authors: Huth JF,Gupta RK,Eilber FR,Morton DL

    更新日期:1984-03-15 00:00:00

  • The use and effectiveness of rituximab maintenance in patients with follicular lymphoma diagnosed between 2004 and 2007 in the United States.

    abstract:BACKGROUND:The authors examined the "real-world" effectiveness of rituximab (R) maintenance therapy (R-maintenance) compared with observation after R-based induction therapy in patients with previously untreated follicular lymphoma (FL) in the United States. METHODS:The National LymphoCare Study is a prospective, mult...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.28659

    authors: Nastoupil LJ,Sinha R,Byrtek M,Zhou X,Taylor MD,Friedberg JW,Link BK,Cerhan JR,Dawson K,Flowers CR

    更新日期:2014-06-15 00:00:00

  • Hormonal treatment for metastatic breast cancer. An Eastern Cooperative Oncology Group Phase III trial comparing aminoglutethimide to tamoxifen.

    abstract:BACKGROUND:Tamoxifen and aminoglutethimide are two hormone therapies reported to be effective palliative approaches for patients with metastatic breast cancer. The current trial was designed to evaluate their relative therapeutic effectiveness. METHODS:Two hundred forty-nine postmenopausal women with advanced breast c...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1002/1097-0142(19940115)73:2<354::aid-cncr28207

    authors: Gale KE,Andersen JW,Tormey DC,Mansour EG,Davis TE,Horton J,Wolter JM,Smith TJ,Cummings FJ

    更新日期:1994-01-15 00:00:00

  • Correlation of molecular human leukocyte antigen typing and outcome in high-risk melanoma patients receiving adjuvant interferon.

    abstract:BACKGROUND:Interferon is approved for adjuvant treatment of patients with stage IIB/III melanoma. The identification of predictive markers that would permit selection of patients would be beneficial. Specific human leukocyte antigen (HLA) class I and II antigens have previously shown an association with response to the...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25211

    authors: Gogas H,Kirkwood JM,Falk CS,Dafni U,Sondak VK,Tsoutsos D,Stratigos A,Markopoulos C,Pectasides D,Spyropoulou-Vlachou M

    更新日期:2010-09-15 00:00:00

  • Endometrial carcinoma associated with breast carcinoma: low incidence with tamoxifen use.

    abstract:BACKGROUND:Women treated with tamoxifen for breast cancer are at increased risk of endometrial cancer. This study examines the experience at Roswell Park Cancer Institute (RPCI) with women diagnosed with both endometrial carcinoma (EC) and breast carcinoma (BC) to determine the risk and stage of endometrial carcinoma a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0142(19960515)77:10<2058::AID-C

    authors: Cuenca RE,Giachino J,Arredondo MA,Hempling R,Edge SB

    更新日期:1996-05-15 00:00:00

  • Aggressive cutaneous malignancies following cardiothoracic transplantation: the Australian experience.

    abstract:BACKGROUND:The development of malignancies in recipients of a cardiothoracic transplant (CTT)--that is, heart, lung, or heart and lung recipients-is of concern. Cutaneous and lymphoproliferative malignancies comprise the two major groups of malignancies encountered. A small subgroup of patients will develop potentially...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Veness MJ,Quinn DI,Ong CS,Keogh AM,Macdonald PS,Cooper SG,Morgan GW

    更新日期:1999-04-15 00:00:00

  • Transition of Ki-67 index of uterine cervical tumors during radiation therapy. Immunohistochemical study.

    abstract::Histopathologic and Ki-67-staining features of cancer cells were investigated in biopsy specimens before and during radiation therapy in 29 patients with cervical squamous cell carcinoma. No morphologic changes were observed up to doses of 540 cGy. A few intact cancer cells remained up to doses of 2700 cGy. Moderate c...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910801)68:3<517::aid-cncr28206

    authors: Nakano T,Oka K

    更新日期:1991-08-01 00:00:00

  • Sequential half-body irradiation in lymphomatoid granulomatosis. Report of a case and an immunohistologic study.

    abstract::A case is presented of a man with ulcerating skin nodules who was diagnosed by histologic and immunohistologic analysis of skin biopsy specimens as having lymphomatoid granulomatosis (LYG). Phenotypic studies showed the majority of the infiltrating cells to be activated CD4+ T-lymphocytes. The disease followed a rapid...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890215)63:4<652::aid-cncr28206

    authors: Atkinson CH,Davis AL,Colls BM,Wolever TH,Burry AF,Hart DN

    更新日期:1989-02-15 00:00:00

  • Transcatheter hepatic arterial embolization followed by hepatic resection for the spontaneous rupture of hepatocellular carcinoma.

    abstract::In three cases of the spontaneous rupture of hepatocellular carcinoma, emergent transcatheter hepatic arterial embolization was performed for controlling the intraperitoneal hemorrhage. No more transfusions were required after embolization. Operation was carried out on the 10th, 5th, and 5th day, respectively, after l...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860715)58:2<332::aid-cncr28205

    authors: Chen MF,Jan YY,Lee TY

    更新日期:1986-07-15 00:00:00

  • Comparison of clinical staging algorithms and 111indium-capromab pendetide immunoscintigraphy in the prediction of lymph node involvement in high risk prostate carcinoma patients.

    abstract:BACKGROUND:The pretherapy prediction of occult lymph node involvement and the avoidance of otherwise futile and potentially morbid definitive local therapy is paramount in men with newly diagnosed prostate carcinoma. To identify patients with prostate carcinoma who likely have lymph node involvement and would benefit f...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:

    authors: Polascik TJ,Manyak MJ,Haseman MK,Gurganus RT,Rogers B,Maguire RT,Partin AW

    更新日期:1999-04-01 00:00:00

  • Clinical application of estrogen receptor in breast cancer.

    abstract::Patients with ER positive primary tumors usually have initial metastases at the more favorable sites. Twelve out of 14 patients with ER positive had first site of metastases in either bone or soft tissue. In contrast, 13 of 17 patients with negative ER developed first metastases in viscera. ER positive patients respon...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19801215)46:12+<2932::aid-cncr28

    authors: Singhakowinta A,Saunders DE,Brooks SC,Samal B,Vaitkevicius VK

    更新日期:1980-12-15 00:00:00

  • MicroRNA profiling of adrenocortical tumors reveals miR-483 as a marker of malignancy.

    abstract:BACKGROUND:The authors are interested in identifying molecular markers that can aid in the diagnosis of adrenocortical carcinoma (ACC). The aim of this study was to identify microRNAs (miRNAs or miRs) that are differentially expressed in malignant adrenocortical tumors as compared with benign tumors and assess their po...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25724

    authors: Patterson EE,Holloway AK,Weng J,Fojo T,Kebebew E

    更新日期:2011-04-15 00:00:00

  • Uveal melanoma: From diagnosis to treatment and the science in between.

    abstract::Melanomas of the choroid, ciliary body, and iris of the eye are collectively known as uveal melanomas. These cancers represent 5% of all melanoma diagnoses in the United States, and their age-adjusted risk is 5 per 1 million population. These less frequent melanomas are dissimilar to their more common cutaneous melano...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.29727

    authors: Chattopadhyay C,Kim DW,Gombos DS,Oba J,Qin Y,Williams MD,Esmaeli B,Grimm EA,Wargo JA,Woodman SE,Patel SP

    更新日期:2016-08-01 00:00:00

  • Outcome in 34 patients with juvenile-onset mycosis fungoides: a clinical, immunophenotypic, and molecular study.

    abstract:BACKGROUND:Mycosis fungoides (MF) is predominantly a disease of older patients, but occasionally occurs in children. The aims of the current study were to describe the clinical presentation, pathologic features, and disease progression (DP) in patients who developed MF before age 16 years. METHODS:A retrospective stud...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11780

    authors: Wain EM,Orchard GE,Whittaker SJ,Spittle M Sc MF,Russell-Jones R

    更新日期:2003-11-15 00:00:00

  • Bladder cancer as seen in giant histologic sections.

    abstract::Giant sections from cystectomy specimens in 45 cases of bladder cancer were examined microscopically after en bloc fixation and processing. There were 35 transitional cell, seven squamous cell, and three mixed transitional cell and squamous carcinomas. Broad front invasion was associated with papillary and superficial...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197702)39:2<447::aid-cncr2820390

    authors: Soto EA,Friedell GH,Tiltman AJ

    更新日期:1977-02-01 00:00:00

  • Remission maintenance for acute nonlymphocytic leukemia: cytosine arabinoside plus 6-thioguanine versus a sequence of drug regimens.

    abstract::In order to determine whether the use of a sequence of chemotherapeutic regimens plus BCG could produce longer durations of remission in adult acute nonlymphocytic leukemia than maintenance therapy with cytosine arabinoside, 6-thioguanine, plus BCG, a randomized study was performed at Washington University. Upon achie...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(19800701)46:1<22::aid-cncr282046

    authors: Presant CA,Berger NA,Klahr C,Phillips GL

    更新日期:1980-07-01 00:00:00

  • Estrogen receptors in patients with malignant melanoma.

    abstract::We detected cytoplasmic estrogen receptors (ER) in only 4 of 34 (12%) patients with malignant melanoma. The titers as assayed by the dextran-coated charcoal method were 3, 3, 4, and 5 fmol/mg, respectively. Our data indicate that the incidence of melanoma with detectable ER is low, which suggests that any potential cl...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19801015)46:8<1785::aid-cncr2820

    authors: Creagan ET,Ingle JN,Woods JE,Pritchard DJ,Jiang NS

    更新日期:1980-10-15 00:00:00

  • Mutations of the p53 gene in male breast cancer.

    abstract:BACKGROUND:Cancer of the male breast (MBC) is rare, accounting for less than 1% of cancer in males and representing less than 1% of all breast cancers. Reports of abnormalities in the expression of the tumor suppressor gene p53 in MBC have been few. METHODS:To assess the expression and mutations of the p53 gene, 35 pa...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950501)75:9<2233::aid-cncr2820

    authors: Anelli A,Anelli TF,Youngson B,Rosen PP,Borgen PI

    更新日期:1995-05-01 00:00:00

  • Adenoid cystic carcinoma of the salivary gland. Sustained complete response to chemotherapy.

    abstract::A patient developed widely metastatic adenoid cystic carcinoma of the parotid gland after several local recurrences. A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C. This is the second complete response ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830215)51:4<589::aid-cncr28205

    authors: Budd GT,Groppe CW

    更新日期:1983-02-15 00:00:00

  • Long-term outcomes of adult survivors of childhood cancer.

    abstract::During the past 30 years, changes in the treatment of children and adolescents with cancer have led to substantial improvements in survival. Although treatment-related factors have been shown to impact subsequent health status and quality of life, there is limited information on survivors who are now two or more decad...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.21249

    authors: Robison LL,Green DM,Hudson M,Meadows AT,Mertens AC,Packer RJ,Sklar CA,Strong LC,Yasui Y,Zeltzer LK

    更新日期:2005-12-01 00:00:00

  • Phase II studies of methyl glyoxal bis-guanylhydrazone (NSC 32946) in carcinoma of the colon and lung.

    abstract::We have tested methyl glyoxal bis-guanyl hydrazone (NSC 32946) for antitumor activity in patients with colorectal carcinoma and non-small cell bronchogenic carcinoma. The drug dose was 500 mg/m2 administered by single weekly injection, and with a provision dose escalation. No responses were seen in 38 evaluable patien...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19821001)50:7<1258::aid-cncr2820

    authors: Killen JY,Mitchell EP,Hoth DF,Willis LL,Gullo JJ,Smith FP,Schein PS,Woolley PV

    更新日期:1982-10-01 00:00:00