Fibrosis in the peritoneum induced by scirrhous gastric cancer cells may act as "soil" for peritoneal dissemination.

abstract：:A retrospective study is reported of 120 consecutive cases of patients presenting with brain metastases as the primary sign of their malignancy. Primary site was found in 62 patients (53 while alive and 9 at postmortem examination) and remained unknown in 58. Lung was the most frequent primary site (45% of known sites...

journal_title：Cancer

authors： Le Chevalier T,Smith FP,Caille P,Constans JP,Rouesse JG

更新日期：1985-08-15 00:00:00

abstract：BACKGROUND:The optimal imaging for the staging of oropharyngeal cancer is not well defined. METHODS:The linked Surveillance, Epidemiology, and End Results (SEER)-Medicare database for 2006 through 2011 was used to compare patient characteristics and hospital region by the initial imaging modality used for patients wit...

journal_title：Cancer

authors： Morgan RL,Eguchi MM,Mueller AC,Daugherty SL,Amini A,Karam SD

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:Malignant peritoneal mesothelioma is a rare and fatal disease. Until recently, the treatment options were very limited and ineffective. The new comprehensive approach of cytoreductive surgery with perioperative intraperitoneal chemotherapy offers improved survival rates at a cost of considerable morbidity an...

journal_title：Cancer

authors： Yan TD,Haveric N,Carmignani CP,Chang D,Sugarbaker PH

更新日期：2005-02-15 00:00:00

abstract：BACKGROUND:Patient safety is a critical concern in clinical oncology, but the ability to measure adverse events (AEs) across cancer care is limited by a narrow focus on treatment-related toxicities. The objective of this study was to assess the nature and extent of AEs among cancer patients across inpatient and outpati...

journal_title：Cancer

authors： Lipitz-Snyderman A,Pfister D,Classen D,Atoria CL,Killen A,Epstein AS,Anderson C,Fortier E,Weingart SN

更新日期：2017-12-01 00:00:00

abstract：:This protocol study (SWOG-7431) combining adriamycin and methyl CCNU (MAD) for metastatic sarcomas was initially used on patients who were refractory to cytoxan, vincristine, and/or actinomycin-D. After the initial good results, the study was expanded to include any untreated patients with metastatic sarcoma. The init...

journal_title：Cancer

authors： Rivkin SE,Gottlieb JA,Thigpen T,El Mawla NG,Saiki J,Dixon DO

更新日期：1980-08-01 00:00:00

abstract：:In the treatment of gynecologic malignancies, various combinations of surgery, drugs, and radiation therapy are used with increasing frequency. An examination is made of data dealing with combined modalities in the treatment of tumors of the cervix, endometrium, and ovary. Although the efficacy of such treatments has ...

journal_title：Cancer

authors： Brady LW

更新日期：1975-01-01 00:00:00

abstract：:Transcriptional dysregulation induced by disease-defining genetic alterations of proteins in transcriptional machinery is a key feature of cancers. Mediator complex subunit 12 (MED12) is the central architectural subunit in the kinase module of Mediator, a large transcriptional regulatory complex that controls essenti...

journal_title：Cancer

authors： Zhang S,O'Regan R,Xu W

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:The prognostic significance and optimal care of children with differentiated thyroid cancer and pulmonary metastases are not well established. METHODS:Of 209 patients younger than 25 years of age who were treated at University of Texas M. D. Anderson Cancer Center between 1960 and 1990 and for whom there wa...

journal_title：Cancer

authors： Vassilopoulou-Sellin R,Klein MJ,Smith TH,Samaan NA,Frankenthaler RA,Goepfert H,Cangir A,Haynie TP

更新日期：1993-02-15 00:00:00

abstract：BACKGROUND:Several histologic classifications of thymomas have been proposed, and attempts have been made to correlate the different histologic subtypes to clinical behavior and prognosis. Recently, Marino and Müller-Hermelink and Kirchner et al. proposed a new morphologic classification of thymomas based on the resemb...

journal_title：Cancer

authors： Quintanilla-Martinez L,Wilkins EW Jr,Choi N,Efird J,Hug E,Harris NL

更新日期：1994-07-15 00:00:00

abstract：BACKGROUND:Controlled-release (CR) morphine tablets have become routine therapy in the management of cancer pain. Compared with immediate-release (IR) morphine, this formulation provides the benefit of dosing every 12 hours. METHODS:This study reviewed the 10 published, well controlled, repeated-dose, comparative stud...

journal_title：Cancer

authors： Warfield CA

更新日期：1998-06-15 00:00:00

abstract：BACKGROUND:Disseminated intravascular coagulation (DIC) and primary fibrinolysis have both been reported in association with prostate carcinoma. The correct diagnosis of the coagulopathy can be difficult and the appropriate management controversial. METHODS:A case is presented of a man in whom DIC and soft tissue hemo...

journal_title：Cancer

authors： Cooper DL,Sandler AB,Wilson LD,Duffy TP

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...

journal_title：Cancer

authors： Baddoura FK,Unger ER,Mufarrij A,Nassar VH,Zaki SR

更新日期：1994-09-15 00:00:00

abstract：BACKGROUND:We previously reported that a single prostate-specific antigen (PSA) measured at ages 44-50 was highly predictive of subsequent prostate cancer diagnosis in an unscreened population. Here we report an additional 7 years of follow-up. This provides replication using an independent data set and allows estimate...

journal_title：Cancer

authors： Lilja H,Cronin AM,Dahlin A,Manjer J,Nilsson PM,Eastham JA,Bjartell AS,Scardino PT,Ulmert D,Vickers AJ

更新日期：2011-03-15 00:00:00

abstract：:To test the hypothesis that there is a positive association between chronic alcoholism and carcinoma of the pancreas, the mortality experience of 1382 chronic alcoholics was studied. Analysis was limited to a comparison of observed and expected proportional mortality of different causes of death in the 894 whites who ...

journal_title：Cancer

authors： Monson RR,Lyon JL

更新日期：1975-09-01 00:00:00

abstract：:Seventy-eight patients with disseminated testicular cancer were entered on a random prospective study evaluating three separate remission induction arms. Therapy with cis-diamminedichloroplatinum (20 mg/M2 for five consecutive days every three weeks for 3-4 courses) and bleomycin (30 units intravenous push weekly for ...

journal_title：Cancer

authors： Einhorn LH,Williams SD

更新日期：1980-09-15 00:00:00

abstract：BACKGROUND:There is no clear consensus between pediatric and adult providers about the treatment of adolescents and young adults (AYAs) with Hodgkin lymphoma (HL). METHODS:Failure-free survival (FFS) and overall survival (OS) were compared between 114 patients ages 17 to 21 years with HL who were treated on the Easter...

journal_title：Cancer

authors： Henderson TO,Parsons SK,Wroblewski KE,Chen L,Hong F,Smith SM,McNeer JL,Advani RH,Gascoyne RD,Constine LS,Horning S,Bartlett NL,Shah B,Connors JM,Leonard JI,Kahl BS,Kelly KM,Schwartz CL,Li H,Friedberg JW,Friedman D

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The treatment of metastatic renal cell carcinoma (RCC) with high-dose interleukin-2 (HD IL-2) has resulted in durable tumor regression in a minority of patients. The current study presents the authors' 20-year experience administering this immunotherapeutic agent. METHODS:Patients with metastatic RCC (n = 2...

journal_title：Cancer

authors： Klapper JA,Downey SG,Smith FO,Yang JC,Hughes MS,Kammula US,Sherry RM,Royal RE,Steinberg SM,Rosenberg S

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:There has been increasing interest in the primary surgical treatment of patients with early T classification (T1-T2) oropharyngeal squamous cell carcinoma (OPSCC), with the stated goal of de-escalating or avoiding adjuvant treatment. Herein, the authors sought to determine the degree to which this interest h...

journal_title：Cancer

authors： Cracchiolo JR,Baxi SS,Morris LG,Ganly I,Patel SG,Cohen MA,Roman BR

更新日期：2016-05-15 00:00:00

abstract：BACKGROUND:A novel pancreatic carcinoma cell line, FAMPAC, was identified from investigation of poorly differentiated pancreatic adenocarcinoma cells found in a patient with a familial predisposition to pancreatic carcinoma. A gene responsible for familial pancreatic carcinoma has not been identified to date. METHODS:...

journal_title：Cancer

authors： Eisold S,Ryschich E,Linnebacher M,Giese T,Nauheimer D,Wild A,Bartsch DK,Büchler MW,Schmidt J

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Screening is effective in reducing the incidence and mortality of colorectal cancer. Rates of colorectal cancer test use continue to be low. METHODS:The authors analyzed data from the National Health Interview Survey concerning the use of the home-administered fecal occult blood test (FOBT) and sigmoidoscop...

journal_title：Cancer

authors： Seeff LC,Nadel MR,Klabunde CN,Thompson T,Shapiro JA,Vernon SW,Coates RJ

更新日期：2004-05-15 00:00:00

abstract：:The case of a European patient with a malignant lymphoepithelial lesion of epithelial type is presented. This type of tumor has an exceptionally high incidence among Eskimos. To the authors' knowledge this is the first case reported with an ultrastructural study that demonstrates the squamous nature of the tumor cells...

journal_title：Cancer

authors： Redondo C,Garcia A,Vazquez F

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:Even when they are analogous in microscopic and macroscopic appearance, tumors vary in their response rates to radiotherapy. Cell culture and xenograft experiments with colorectal cell lines have demonstrated that wild-type p53 increases radiosensitivity. Hence, the authors investigated, in a well-defined po...

journal_title：Cancer

authors： Nehls O,Klump B,Holzmann K,Lammering G,Borchard F,Gruenagel HH,Gaco V,Gregor M,Porschen R

更新日期：1999-06-15 00:00:00

abstract：:One hundred fifteen patients underwent surgical treatment of renal cell carcinoma. Survival time was analyzed by statistical regression methods in order to determine the joint significance of stage, using both the Robson and TNM classifications, histologic grade, cell type, and demographic features of the patient samp...

journal_title：Cancer

authors： Selli C,Hinshaw WM,Woodard BH,Paulson DF

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:The American Joint Committee on Cancer (AJCC) 7th edition introduced major changes in the staging of lung cancer, including the tumor (T), node (N), metastasis (M)-TNM-system and new stage/prognostic site-specific factors (SSFs), collected under the Collaborative Stage Version 2 (CSv2) Data Collection System...

journal_title：Cancer

authors： Chen VW,Ruiz BA,Hsieh MC,Wu XC,Ries LA,Lewis DR

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Breast conservation is now established treatment for patients with small breast cancers. The authors reviewed a large series of patients with long term follow-up who underwent conservative treatment. Clinical and pathologic factors were analyzed to identify patients at an increased risk of relapse in the bre...

journal_title：Cancer

authors： Dewar JA,Arriagada R,Benhamou S,Benhamou E,Bretel JJ,Pellae-Cosset B,Marin JL,Petit JY,Contesso G,Sarrazin D

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Cetuximab in combination with docetaxel was examined in chemotherapy-refractory/resistant patients with advanced nonsmall-cell lung cancer (NSCLC) to determine response rate, survival, safety, and pharmacokinetics (PK). METHODS:Patients had evidence of epidermal growth factor receptor (EGFR) expression (> o...

journal_title：Cancer

authors： Kim ES,Mauer AM,William WN Jr,Tran HT,Liu D,Lee JJ,Windt P,Hong WK,Vokes EE,Herbst RS

更新日期：2009-04-15 00:00:00

abstract：METHODS:The prognostic significance of flow cytometric analysis in patients with node-negative invasive breast carcinoma was evaluated in a retrospective series of 158 patients with a minimum follow-up study of 9 years. RESULTS:The ploidy status could be assessed in 147 specimens (93%), and the proliferative phase or ...

journal_title：Cancer

authors： Bosari S,Lee AK,Tahan SR,Figoni MA,Wiley BD,Heatley GJ,Silverman ML

更新日期：1992-10-01 00:00:00

abstract：:The concept of second-look surgery was introduced by Wangensteen 25 years ago, and 17% of patients were reported to be converted to a cancer-free state. Instead of an arbitrary time interval for reoperation, serial CEA values were used as the indicator of colon cancer recurrence and second-look operation. Twenty-two r...

journal_title：Cancer

authors： Minton JP,Martin EW Jr

更新日期：1978-09-01 00:00:00

abstract：:Of a total of 1561 patients registered in the Intergroup Rhabdomyosarcoma Study (IRS) as of May 1983, 78 patients (5%) were younger than 1 year of age. These infants did not differ from the older children (1-20 years of age) in male/female ratio, clinical grouping, or survival rates. Infants younger than 1 year of age...

journal_title：Cancer

authors： Ragab AH,Heyn R,Tefft M,Hays DN,Newton WA Jr,Beltangady M

更新日期：1986-12-15 00:00:00

abstract：BACKGROUND:Patients with advanced soft tissue sarcomas (STS) have limited therapeutic options. Sorafenib (BAY 43-9006) is a multitargeted tyrosine kinase inhibitor of raf, vascular endothelial growth factor receptors 1 (VEGFR1) through 3, platelet-derived growth factor B, fms-like tyrosine kinase 3, and c-kit, and some...

journal_title：Cancer

authors： von Mehren M,Rankin C,Goldblum JR,Demetri GD,Bramwell V,Ryan CW,Borden E

更新日期：2012-02-01 00:00:00