Combined modality therapy of gynecologic cancer.

abstract：BACKGROUND:There is no standard therapy for surgery- and radiotherapy-resistant, recurrent, low-grade spinal cord gliomas. Therefore, a retrospective study of temozolomide (TMZ) in adults with recurrent low-grade spinal cord gliomas with a primary objective of determining progression-free survival (PFS) was performed. ...

journal_title：Cancer

authors： Chamberlain MC

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Total body irradiation (TBI) is commonly used with autologous bone marrow transplantation (BMT) for treatment of hematologic malignancies. Pulmonary complications of TBI can cause long-term morbidity and mortality. The authors have compared the pulmonary toxicity and efficacy of two different TBI fractionati...

journal_title：Cancer

authors： Gopal R,Ha CS,Tucker SL,Khouri IF,Giralt SA,Gajewski JL,Andersson BS,Cox JD,Champlin RE

更新日期：2001-10-01 00:00:00

abstract：:Clinical, histological and ultrastructural features of three small cell carcinomas arising in the parotid gland are presented. The light microscopic appearance of two of the neoplasms suggested neuroendocrine cell derivation, confirmed by electron microscopy in both instances. The fine structure of the third neoplasm ...

journal_title：Cancer

authors： Kraemer BB,Mackay B,Batsakis JG

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Small cell glioblastoma (GBM) is a variant with monomorphous, deceptively bland nuclei that often is misdiagnosed as anaplastic oligodendroglioma. METHODS:To elucidate its clinicopathologic and genetic features, the authors studied 71 adult patients (median age, 57 years), including 22 patients who were ide...

journal_title：Cancer

authors： Perry A,Aldape KD,George DH,Burger PC

更新日期：2004-11-15 00:00:00

abstract：:The unique characteristics of tumor vasculature represent an attractive target that may be exploited by vascular-targeting anticancer agents. A promising strategy involves the selective disruption of established tumor blood vessels by tumor-vascular disrupting agents (tumor-VDAs), which exhibit antivascular activity, ...

journal_title：Cancer

authors： McKeage MJ,Baguley BC

更新日期：2010-04-15 00:00:00

abstract：:CA 125 and steroid production is compared in a group of 48 women with ovarian epithelial carcinoma. The histologic types were I C (n = 20), II C (n = 5), III C (n = 11), or V (n = 12). The number of patients in Stage I was six; Stage II, 11; Stage III, 16; and Stage IV, 15. All patients were naturally or surgically po...

journal_title：Cancer

authors： Mählck CG,Grankvist K,Kjellgren O,Bäckström T

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Clinical practice guidelines for the management of breast carcinoma were introduced in Australia in October, 1995. This article describes the management of early-stage breast carcinoma both before and after the introduction of these guidelines. METHODS:All cases of early breast carcinoma that were diagnosed...

journal_title：Cancer

authors： White V,Pruden M,Giles G,Collins J,Jamrozik K,Inglis G,Boyages J,Hill D

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Randomized controlled trials (RCTs) are commonly used to inform clinical practice; however, it is unclear how generalizable RCT data are to patients in routine clinical practice. The authors of this report assessed the availability and applicability of randomized evidence guiding medical decisions in a cohor...

journal_title：Cancer

authors： Apisarnthanarax S,Swisher-McClure S,Chiu WK,Kimple RJ,Harris SL,Morris DE,Tepper JE

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:The prognosis of patients with clinically staged hilar nodal involvement (Stage N1) or clinical Stage II non-small cell lung cancer (NSCLC, Stage T1-2N1M0) treated with radiation therapy (RT) alone is not well established. METHODS:Records of 758 patients with clinical Stage I-III NSCLC treated with RT were ...

journal_title：Cancer

authors： Rosenthal SA,Curran WJ Jr,Herbert SH,Hughes EN,Sandler HM,Stafford PM,McKenna WG

更新日期：1992-11-15 00:00:00

abstract：BACKGROUND:Glembatumumab vedotin is an antibody-drug conjugate that produced preliminary clinical activity against advanced melanoma in a phase 1 dose-escalation trial. The objective of the current study was to investigate further the antitumor activity of glembatumumab vedotin at the recommended phase 2 dose in heavil...

journal_title：Cancer

authors： Ott PA,Pavlick AC,Johnson DB,Hart LL,Infante JR,Luke JJ,Lutzky J,Rothschild NE,Spitler LE,Cowey CL,Alizadeh AR,Salama AK,He Y,Hawthorne TR,Bagley RG,Zhang J,Turner CD,Hamid O

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND METHODS:The antiemetic activity of ondansetron (Zofran, Glaxo Pharmaceuticals, Research Triangle Park, NC) was evaluated in 25 patients with recurrent melanoma who were treated sequentially with dacarbazine (DTIC), vinblastine, and cisplatin. The antiemetic regimen included ondansetron alone in 11 patien...

journal_title：Cancer

authors： Legha SS,Hodges C,Ring S

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Forty-eight patients with resected Stages IIA and IIB melanoma were immunized with two tumor antigen epitope peptides derived from gp100(209-217) (210M) (IMDQVPSFV) and tyrosinase(368-376) (370D) (YMDGTMSQV) emulsified with incomplete Freund's adjuvant (IFA). Patients were assigned randomly to receive either...

journal_title：Cancer

authors： Weber J,Sondak VK,Scotland R,Phillip R,Wang F,Rubio V,Stuge TB,Groshen SG,Gee C,Jeffery GG,Sian S,Lee PP

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Ureteral lesions can be difficult to diagnose. The value of ureteral biopsy in addition to ureteral washings has not been defined clearly. METHODS:All ureteral washings and biopsies with follow-up that were performed at a single institution were reviewed. RESULTS:In total, 39 patients underwent ureteral wa...

journal_title：Cancer

authors： Renshaw AA

更新日期：2006-02-25 00:00:00

abstract：:A case of primary non-Hodgkin's lymphoma of the breast was studied with light and electron microscopy and for immunologic cell markers. With light microscopy, the tumor was seen to be a poorly differentiated lymphocytic lymphoma, diffuse, according to Rappaport's classification. With electron microscopy, the tumor was...

journal_title：Cancer

authors： Tateno M,Yoshiki T,Itoh T,Takamuro M,Saito C

更新日期：1983-08-15 00:00:00

abstract：:The oral cavity, oropharynx and nasopharynx are readily accessible to fine needle aspiration (FNA). This study reviews the author's experience with 93 FNA from these sites: 76 from the oral cavity, eight from the oropharynx, and eight from the nasopharynx. Thirty-nine (42%) of the FNA were positive for malignancy with...

journal_title：Cancer

authors： Scher RL,Oostingh PE,Levine PA,Cantrell RW,Feldman PS

更新日期：1988-12-15 00:00:00

abstract：:Sixty percent of all cancer occurs in persons aged > or =65 years. This article provides an overview of aspects of the burden of cancer in the elderly, highlighting certain demographic and epidemiologic data. It served as a frame of reference for participants in the Oncology Geriatric Education Retreat, San Juan, Puer...

journal_title：Cancer

authors： Yancik R

更新日期：1997-10-01 00:00:00

abstract：:A case-referent study on soft tissue sarcomas (STS) was conducted, to see if previous findings regarding an association between exposure to phenoxyacetic acids or chlorophenols and this tumor type could be reproduced. Fifty-five male STS patients were thereby compared with 220 living and 110 dead population-based refe...

journal_title：Cancer

authors： Hardell L,Eriksson M

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Little is known about the size and characteristics of the decision-support networks of women newly diagnosed with breast cancer and whether their involvement improves breast cancer treatment decisions. METHODS:A population-based sample of patients newly diagnosed with breast cancer in 2014 and 2015, as repo...

journal_title：Cancer

authors： Wallner LP,Li Y,McLeod MC,Hamilton AS,Ward KC,Veenstra CM,An LC,Janz NK,Katz SJ,Hawley ST

更新日期：2017-10-15 00:00:00

abstract：:109 cases of breast cancer were treated by tumorectomy and radiotherapy or radiotherapy alone. Almost 30% with small tumors (T1, T2) were considered inoperable for medical reasons and 70% refused mastectomy. Over the past five years the number of patients refusing mastectomy has definitely increased. 59 cases of surgi...

journal_title：Cancer

authors： Alpert S,Ghossein NA,Stacey P,Migliorelli FA,Efron G,Krishnaswamy V

更新日期：1978-10-01 00:00:00

abstract：:This prospective evaluation of 5-fluorouracil (5-FU) and methyl-CCNU administered in combination to patients with surgery for histologically proved gastric adenocarcinoma is based upon 312 patients randomized between August 1974 and May 1980. Patients were stratified into three categories of resectability, (1) complet...

journal_title：Cancer

authors： Higgins GA,Amadeo JH,Smith DE,Humphrey EW,Keehn RJ

更新日期：1983-09-15 00:00:00

abstract：BACKGROUND:Prior literature has suggested synergy between immune checkpoint therapy (ICT) and radiotherapy (RT) for the treatment of brain metastases (BrM), but to the authors' knowledge the optimal timing of therapy to maximize this synergy is unclear. METHODS:A total of 199 patients with melanoma and non-small cell ...

journal_title：Cancer

authors： Qian JM,Martin AM,Martin K,Hammoudeh L,Catalano PJ,Hodi FS,Cagney DN,Haas-Kogan DA,Schoenfeld JD,Aizer AA

更新日期：2020-12-15 00:00:00

abstract：:Nineteen patients with locally advanced bladder cancer were treated with irradiation and concomitant 5-fluorouracil intravenous infusion with or without bolus mitomycin. Eighteen of the 19 patients were evaluated for local response. Eleven of the 18 patients (61%) obtained a complete local response within 3 to 6 month...

journal_title：Cancer

authors： Rotman M,Macchia R,Silverstein M,Aziz H,Choi K,Rosenthal J,Braverman A,Laungani GB

更新日期：1987-02-15 00:00:00

abstract：BACKGROUND:Immunohistological markers specific for a single type of epithelium are rare. Recently, urothelium tissue-specific genes were cloned. The genes encoded a family of transmembrane proteins, uroplakins, that are expressed only in urothelial mucosa. Using uroplakin antibodies on paraffin-embedded tissue, a previ...

journal_title：Cancer

authors： Xu X,Sun TT,Gupta PK,Zhang P,Nasuti JF

更新日期：2001-06-25 00:00:00

abstract：:Thyroid function and scans were evaluated in fifty disease-free patients 2 to 16 years after receiving neck irradiation for the treatment of Hodgkin's disease. Twenty-five of 50 patients had abnormal thyroid studies: eight were hypothyroid, two were hypothyroid and had abnormal scans, and fifteen had abnormal scans. O...

journal_title：Cancer

authors： Nelson DF,Reddy KV,O'Mara RE,Rubin P

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:Cytologic distinction between follicle center lymphoma (FCL) and mantle cell lymphoma (MCL) is difficult with cytomorphology alone and requires immunophenotyping. The current study describes the distinction between follicle center and mantle cell lymphoma made with fine-needle aspiration (FNA) material. MET...

journal_title：Cancer

authors： Rassidakis GZ,Tani E,Svedmyr E,Porwit A,Skoog L

更新日期：1999-08-25 00:00:00

abstract：:A young woman with a very extensive intramedullary hemangioblastoma of the spinal cord was treated with a moderately high dose of irradiation after biopsy only of the tumor. Now, five years following treatment, there have been no radiation sequelae and no evidence of progressive disease. ...

journal_title：Cancer

authors： Richardson RG,Griffin TW,Parker RG

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Pathologically, benign prostatic hyperplasia (BPH) is not considered a precursor for prostate carcinoma. However, because the two conditions share not only a similar hormonal environment within the prostate but also several common risk factors, it is possible that men with BPH may be at increased risk of pro...

journal_title：Cancer

authors： Chokkalingam AP,Nyrén O,Johansson JE,Gridley G,McLaughlin JK,Adami HO,Hsing AW

更新日期：2003-10-15 00:00:00

abstract：:The clinicopathologic significance of mucus production by adenocarcinoma of the colon and rectum was analyzed in retrospective study with stage matched non-mucus producing control carcinomas. Mucinous carcinoma of the colon and rectum comprised 132 (15%) of 893 cases of colorectal carcinoma. The rectum was the most co...

journal_title：Cancer

authors： Symonds DA,Vickery AL

更新日期：1976-04-01 00:00:00

abstract：:Fifty patients with inoperable squamous carcinoma of the lung. 38 with extensive, and 12 with limited disease, were treated with BACON. Tumor regression greater than 50% was observed in 17 patients (45%) with extensive, and four patients (33%) with limited disease. Stabilization of disease for greater than or equal to...

journal_title：Cancer

authors： Livingston RB,Fee WH,Einhorn LH,Burgess MA,Freireich EJ,Gottlieb JA,Farber MO

更新日期：1976-03-01 00:00:00

abstract：:Seventy-eight patients with metastatic cancer to the lungs underwent flexible fiberoptic bronchoscopy for diagnosis. The patients were divided into two groups by presenting radiographic pattern as: (I) diffuse linear interstitial infiltrations (55 patients); and (II) localized or multiple nodular opacities (23 patient...

journal_title：Cancer

authors： Chuang MT,Padilla ML,Teirstein AS

更新日期：1983-11-15 00:00:00