Abstract:
:A case of primary non-Hodgkin's lymphoma of the breast was studied with light and electron microscopy and for immunologic cell markers. With light microscopy, the tumor was seen to be a poorly differentiated lymphocytic lymphoma, diffuse, according to Rappaport's classification. With electron microscopy, the tumor was seen to consist of a cytologically uniform cell population. The cells were characterized by irregularly shaped nuclei with infrequent cytoplasmic projections and "microvilli-like" structures, mimicking small cleaved follicular center cells. The immunologic cell marker study showed that the cells were positive for surface IgA and HLA-DR antigen; negative for SRBC receptors, Leu 1, Leu 2a, and Leu 3a antigens. The collective evidence indicated the tumor was of B-cell origin.
journal_name
Cancerjournal_title
Cancerauthors
Tateno M,Yoshiki T,Itoh T,Takamuro M,Saito Cdoi
10.1002/1097-0142(19830815)52:4<671::aid-cncr28205subject
Has Abstractpub_date
1983-08-15 00:00:00pages
671-4issue
4eissn
0008-543Xissn
1097-0142journal_volume
52pub_type
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