Tissue diagnosis for carcinoma of the pancreas and periampullary structures.

abstract：BACKGROUND:Topoisomerase I inhibitors, like topotecan, have activity in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML). 9-Nitro-camptothecin (9-NC) is a new oral topoisomerase inhibitor with a good safety profile. The aims of the current study were to evaluate the activity and safety of 9-NC ...

journal_title：Cancer

authors： Quintas-Cardama A,Kantarjian H,O'Brien S,Jabbour E,Giles F,Ravandi F,Faderl S,Pierce S,Shan J,Verstovsek S,Cortes J

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The primary purpose of this study was to establish the maximum tolerated dose (MTD) of intravenous melphalan in combination with paclitaxel and cisplatin plus granulocyte-colony stimulating factor (G-CSF) in patients with suboptimal advanced epithelial ovarian carcinoma or primary peritoneal carcinoma. METH...

journal_title：Cancer

authors： Gershenson DM,Morris M,Burke TW,Levenback C,Wolf J,Lee JJ,Thall PF,Atkinson EN,Silva EG,Wharton JT

更新日期：1999-12-01 00:00:00

abstract：:To evaluate the frequency, etiology, and outcome of diffuse interstitial pneumonitis after treatment of children with Stage IV (favorable histologic type) Wilms' tumor using whole-lung and abdominal radiation therapy, and combination chemotherapy, all cases reported in such patients entered on National Wilms' Tumor St...

journal_title：Cancer

authors： Green DM,Finklestein JZ,Tefft ME,Norkool P

更新日期：1989-02-01 00:00:00

abstract：:Prior studies have shown that black patients with breast cancer have poorer survival times compared with white patients even when adjusted for stage. Seventy-four black patients treated on six Piedmont Oncology Association (POA) protocols were compared with 74 randomly selected white patients treated with the same pro...

journal_title：Cancer

authors： Kimmick G,Muss HB,Case LD,Stanley V

更新日期：1991-06-01 00:00:00

abstract：:Familial polyposis is a genetically-transmitted disease characterized by multiple adenomatous colorectal polyps and a high risk for development of adenocarcinoma. Familial polyposis and Gardner's syndrome should be differentiated from other penetically-linked polyposis syndromes lacking a predisposition for cancer. To...

journal_title：Cancer

authors： DeCosse JJ,Adams MB,Condon RE

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Retrospective studies suggest that dose intensity is an important determinant of outcome in the treatment of patients with a variety of malignant diseases such as breast cancer, ovarian cancer, and lymphoma. Unfortunately, these results have not been clearly substantiated in prospective randomized trials. On...

journal_title：Cancer

authors： Long GD,Negrin RS,Hoyle CF,Kusnierz-Glaz CR,Schriber JR,Blume KG,Chao NJ

更新日期：1995-09-01 00:00:00

abstract：:Leukemic cells from 13 patients with therapy-related acute nonlymphocytic leukemia (ANLL) were studied by electron microscopy. All of the patients had radiotherapy, and/or alkylating agent chemotherapy for other neoplastic disease 25 to 182 months prior to the diagnosis of ANLL. All cases manifested ultrastructural ev...

journal_title：Cancer

authors： McKenna RW,Parkin JL,Foucar K,Brunning RD

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Because angiogenesis may play a role in the pathogenesis of acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS), and thalidomide (Th) has shown significant anti-angiogenic activity, this study was designed to investigate the potential role of Th in the treatment of patients with AML and...

journal_title：Cancer

authors： Cortes J,Kantarjian H,Albitar M,Thomas D,Faderl S,Koller C,Garcia-Manero G,Giles F,Andreeff M,O'Brien S,Keating M,Estey E

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:The authors conducted this study to update their experience with patients who have ovarian serous borderline tumors with noninvasive peritoneal implants, with the objectives of gaining additional insight into the biologic behavior of these tumors and understanding better the effects of postoperative treatmen...

journal_title：Cancer

authors： Gershenson DM,Silva EG,Tortolero-Luna G,Levenback C,Morris M,Tornos C

更新日期：1998-11-15 00:00:00

abstract：:A previous study evaluated two types of endometrial carcinoma: one with, the other without, associated adenomatous hyperplasia (Groups 1 and 2, respectively). On the basis of histologic observations, the study concluded that Group 1 tumors were likely to be estrogen-dependent, whereas Group 2 tumors appeared to repres...

journal_title：Cancer

authors： Deligdisch L,Holinka CF

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:Heat shock protein 60 (Hsp60) is a chaperonin involved in tumorigenesis, but its participation in tumor development and progression is not well understood and its value as a tumor biomarker has not been fully elucidated. In the current study, the authors presented evidence supporting the theory that Hsp60 ha...

journal_title：Cancer

authors： Campanella C,Rappa F,Sciumè C,Marino Gammazza A,Barone R,Bucchieri F,David S,Curcurù G,Caruso Bavisotto C,Pitruzzella A,Geraci G,Modica G,Farina F,Zummo G,Fais S,Conway de Macario E,Macario AJ,Cappello F

更新日期：2015-09-15 00:00:00

abstract：BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...

journal_title：Cancer

authors： Baddoura FK,Unger ER,Mufarrij A,Nassar VH,Zaki SR

更新日期：1994-09-15 00:00:00

abstract：:Routine morphologic and cytochemical study of the leukemic cells of a 13-month-old child did not permit definitive determination of either a lymphoid or a myeloid cell origin. However, ultrastructural cytochemical analysis revealed platelet peroxidase (PPO) reactivity. The malignant cells expressed PPO in both unfixed...

journal_title：Cancer

authors： Sariban E,Oliver C,Corash L,Cossman J,Whang-Peng J,Jaffe ES,Gralnick HR,Poplack DG

更新日期：1984-10-01 00:00:00

abstract：:During 1982 and 1983, 4496 new cases were recorded in the French Registry of acute leukemia and myelodysplastic syndromes by the French Group of Hematologic Morphology. This cooperative group associated members of 37 university centers spread throughout France; these centers handle the overwhelming majority of acute l...

journal_title：Cancer

authors：

更新日期：1987-09-15 00:00:00

abstract：:In this retrospective study, the degree of differentiation of atypical lymphoid cells was assessed in pretreatment cutaneous biopsy specimens from 248 patients with cutaneous T-cell lymphomas (mycosis fungoides and Sézary syndrome) and the findings were correlated with the subsequent therapeutic results. Overall, pati...

journal_title：Cancer

authors： Vonderheid EC,Tam DW,Johnson WC,Van Scott EJ,Wallner PE

更新日期：1981-01-01 00:00:00

abstract：METHODS:The prognostic significance of flow cytometric analysis in patients with node-negative invasive breast carcinoma was evaluated in a retrospective series of 158 patients with a minimum follow-up study of 9 years. RESULTS:The ploidy status could be assessed in 147 specimens (93%), and the proliferative phase or ...

journal_title：Cancer

authors： Bosari S,Lee AK,Tahan SR,Figoni MA,Wiley BD,Heatley GJ,Silverman ML

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Breast carcinoma survivors are the largest segment of the expanding cancer survivor community. As a result, there has been increasing discussion of the safety and efficacy of hormone replacement therapy for women with a past history of breast carcinoma. Little is known about the willingness of older breast c...

journal_title：Cancer

authors： Ganz PA,Greendale GA,Kahn B,O'Leary JF,Desmond KA

更新日期：1999-09-01 00:00:00

abstract：:Two siblings who developed adult T-cell leukemia (ATL) are presented. The patient and 7 of 26 healthy family members examined had the serum antibodies against ATL-associated antigens (ATLA). This family study shows that two main routes of transmission of human T-cell leukemia virus (HTLV) may be involved: one is the r...

journal_title：Cancer

authors： Miyamoto Y,Yamaguchi K,Nishimura H,Takatsuki K,Motoori T,Morimatsu M,Yasaka T,Ohya I,Koga T

更新日期：1985-01-01 00:00:00

abstract：:The hematologic factors of 16 female patients with breast carcinoma who had received adjuvant chemotherapy with L-phenylalanine-based programs for two years were compared with those for 13 normal female volunteers of similar age. The findings include significant suppression of the mean hemoglobin level, of leukocyte c...

journal_title：Cancer

authors： Corder MP,Jochimsen PR

更新日期：1982-06-15 00:00:00

abstract：:The squamous cell carcinoma (SCC) antigen was determined by radioimmunoassay in the serum of 40 untreated patients with SCC of the oromaxillofacial region. The mean (+/- SEM) serum concentration for these patients (3.8 +/- 0.8 ng/ml) was significantly higher than that of 52 disease-free patients coming to routine post...

journal_title：Cancer

authors： Fischbach W,Meyer T,Barthel K

更新日期：1990-03-15 00:00:00

abstract：:Reported are six cases of meningocerebral astrocytomas attached to dura, involving the superficial cortex, in infants under 1 year of age. They represent 1.25% of 483 intracranial tumors in infancy studied at the Children's Hospital in the last 12 years. Five were located in the frontal lobes, with variable extension ...

journal_title：Cancer

authors： Taratuto AL,Monges J,Lylyk P,Leiguarda R

更新日期：1984-12-01 00:00:00

abstract：:The National Polyp Study (NPS) is a multicenter prospective randomized trial designed to evaluate follow-up surveillance strategies in patients who have undergone polypectomy for the control of large bowel cancer. The study design was developed by a joint research committee from American Gastroenterological Associatio...

journal_title：Cancer

authors： Winawer SJ,Zauber AG,O'Brien MJ,Gottlieb LS,Sternberg SS,Stewart ET,Bond JH,Schapiro M,Panish JF,Waye JD

更新日期：1992-09-01 00:00:00

abstract：:Trabecular carcinoma of the skin (Merkel cell tumor), a neoplasm of putative neural origin, must be differentiated from other small cell tumors primary or metastatic to skin. In order to provide more objective diagnostic criteria, four were examined using monoclonal antibodies against neurofilament proteins (NF) and a...

journal_title：Cancer

authors： Leff EL,Brooks JS,Trojanowski JQ

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:To evaluate the immunologic activity of regional lymph nodes, the phenotype of lymphocytes and the functional expression of cell adhesion molecules (CAMs) on lymph node lymphocytes (LNL-: uninvolved, LNL+: involved) were investigated in patients with gastrointestinal carcinoma. METHODS:The lymphocyte subpop...

journal_title：Cancer

authors： Shinkal H,Kitayama J,Kimura W,Muto T,Shibata Y

更新日期：1996-10-15 00:00:00

abstract：BACKGROUND:The Women's Health Initiative randomized clinical trial reported that menopausal hormone therapy increases lung cancer mortality risk. If this is true, use of anti-estrogens should be associated with decreased lung cancer mortality risk. The authors compared lung cancer incidence and mortality among breast c...

journal_title：Cancer

authors： Bouchardy C,Benhamou S,Schaffar R,Verkooijen HM,Fioretta G,Schubert H,Vinh-Hung V,Soria JC,Vlastos G,Rapiti E

更新日期：2011-03-15 00:00:00

abstract：:A patient developed widely metastatic adenoid cystic carcinoma of the parotid gland after several local recurrences. A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C. This is the second complete response ...

journal_title：Cancer

authors： Budd GT,Groppe CW

更新日期：1983-02-15 00:00:00

abstract：:The authors describe the results of a hospital-based incident case-control study of lung cancer conducted in a high-risk region of southern Louisiana from January 1979 through April 1982. Dietary intake of carotene, retinol, and vitamin C was estimated from food frequency questionnaires administered to 1253 cases and ...

journal_title：Cancer

authors： Fontham ET,Pickle LW,Haenszel W,Correa P,Lin YP,Falk RT

更新日期：1988-11-15 00:00:00

abstract：:Platelet kinetics were studied in 70 patients with testicular cancer to elicit the agent responsible for chemotherapy-induced transient early-onset thrombocytopenia; 204 treatment courses were analyzed using three different therapy protocols, which contained vinblastine and bleomycin either alone or in combination wit...

journal_title：Cancer

authors： Steurer G,Kuzmits R,Pavelka M,Sinzinger H,Fritz E,Ludwig H

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Reconstruction is rarely incorporated into the decision-making process for surgical breast cancer treatment. We examined the importance of knowing about reconstruction to patients' surgical decision-making for breast cancer. METHODS:We surveyed women aged < or =79 years with breast cancer (N = 1844) who wer...

journal_title：Cancer

authors： Alderman AK,Hawley ST,Waljee J,Mujahid M,Morrow M,Katz SJ

更新日期：2008-02-01 00:00:00

abstract：:Forty-five immunocompetent patients with solid tumors were immunized with BCG, PPD, and tumor cells. The methods were practical, but the morbidity was significant, including painful draining ulcerations at vaccine sites, possible enhancement of tumor growth in three patients, and the discovery at autopsy of systemic t...

journal_title：Cancer

authors： Gerner RE,Moore GE

更新日期：1976-07-01 00:00:00