Marrow neutrophil reserve after adjuvant chemotherapy for carcinoma of the breast.

Abstract:

:The hematologic factors of 16 female patients with breast carcinoma who had received adjuvant chemotherapy with L-phenylalanine-based programs for two years were compared with those for 13 normal female volunteers of similar age. The findings include significant suppression of the mean hemoglobin level, of leukocyte counts, and of circulating neutrophils and lymphocytes in patients 3-27 months after chemotherapy. Marrow neutrophil reserve studies with prednisolone stimulation again demonstrated significant suppression for the patients who had received chemotherapy. The authors conclude that there is a chronic hematologic toxicity associated with this therapy.

journal_name

Cancer

journal_title

Cancer

authors

Corder MP,Jochimsen PR

doi

10.1002/1097-0142(19820615)49:12<2455::aid-cncr282

subject

Has Abstract

pub_date

1982-06-15 00:00:00

pages

2455-8

issue

12

eissn

0008-543X

issn

1097-0142

journal_volume

49

pub_type

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