Multiple primary cancer risk in patients with squamous cell carcinoma of the oral cavity.

abstract：BACKGROUND:Informed consent has been proposed as the optimal method for ensuring the ethical entry of patients into clinical trials. However, it is known that problems with informed consent exist from the perspective of both patients and physicians. This has led to the suggestion that a third party, such as a research ...

journal_title：Cancer

authors： Loh WY,Butow PN,Brown RF,Boyle F

更新日期：2002-12-01 00:00:00

abstract：:An unusual case of myeloproliferative disorder in which mature and immature myeloid cells were found to contain unusual cytoplasmic inclusions is reported. By light microscopy, these inclusions could be observed with Wright's stain. By electron microscopy they appeared to consist of a pale, finely granular material wi...

journal_title：Cancer

authors： Coppola A,O'Connor J

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMP) are a gene family of zinc enzymes capable of degrading almost all of the extracellular matrix macromolecules in vivo. Their enzymic activities are believed to be responsible for tumor invasion and metastasis. METHODS:In this study, using peroxidase-antiperoxidase method, mono...

journal_title：Cancer

authors： Shima I,Sasaguri Y,Kusukawa J,Yamana H,Fujita H,Kakegawa T,Morimatsu M

更新日期：1992-12-15 00:00:00

abstract：:Surgery is the most effective treatment for thyroid cancer; however, in some subsets of patients, the role of radiotherapy (RT) is important. The main indication for external-beam RT is incomplete surgery. When neoplastic tissue is left behind at operation, RT must be considered, but only if an experienced surgeon fee...

journal_title：Cancer

authors： Tubiana M,Haddad E,Schlumberger M,Hill C,Rougier P,Sarrazin D

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Between 1980-1990, 126 patients were treated with radiation therapy (RT) and hyperthermia using 915-MHz external microwave applicators. All but 11 patients had failed to respond to previous therapy. METHODS:The mean tumor volume was 73 +/- 13 cm3, and the mean radiation dose delivered was 45 +/- 1 Gy. Hyper...

journal_title：Cancer

authors： Engin K,Leeper DB,Tupchong L,Waterman FM,Mansfield CM

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Although delay to diagnosis after a breast screening abnormality causes anxiety, its effect on prognosis is unknown. METHODS:Using pooled data from five Canadian organized breast cancer screening programs, the authors used unconditional logistic regression to evaluate the effect of delay to diagnosis on pro...

journal_title：Cancer

authors： Olivotto IA,Gomi A,Bancej C,Brisson J,Tonita J,Kan L,Mah Z,Harrison M,Shumak R

更新日期：2002-04-15 00:00:00

abstract：BACKGROUND:The staging system for non-small cell lung cancer (NSCLC) does not consider tumor burden or number of metastatic sites, although oligometastases are more favorable. METHODS:Using log-rank testing, the authors analyzed overall survival (OS) in 1284 patients newly presenting with metastatic NSCLC by number of...

journal_title：Cancer

authors： Oh Y,Taylor S,Bekele BN,Debnam JM,Allen PK,Suki D,Sawaya R,Komaki R,Stewart DJ,Karp DD

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Granular cell tumors (GCTs) are uncommon tumors of putative schwannian derivation that are rarely malignant. Although recent studies have addressed a histologic correlation with malignant behavior, similar studies have not been done on cytologic material. METHODS:The authors evaluated 3 malignant GCTs and 1...

journal_title：Cancer

authors： Wieczorek TJ,Krane JF,Domanski HA,Akerman M,Carlén B,Misdraji J,Granter SR

更新日期：2001-12-25 00:00:00

abstract：BACKGROUND:DNA ploidy and S-phase fraction measured by DNA flow cytometry were shown to correlate with several clinicopathologic characteristics in several types of tumors. METHODS:DNA flow cytometry was performed on 329 samples (164 normal mucosa, 165 tumors) obtained from 165 patients (112 men) with stomach cancer, ...

journal_title：Cancer

authors： Lee KH,Lee JS,Suh C,Ahn MJ,Kim SW,Doh BS,Min YI,Kim BS,Park KC,Lee IC

更新日期：1993-09-15 00:00:00

abstract：:Two hundred seventy-nine consecutive patients with Stage II osteogenic sarcoma of the appendicular skeleton treated between 1976 and 1986 were studied to identify predictors of long-term survival. Survival was 77% and 73% at 5 and 10 years, respectively, with continuously disease-free survival being 70% and 69%. On un...

journal_title：Cancer

authors： Glasser DB,Lane JM,Huvos AG,Marcove RC,Rosen G

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:: Although platinum-based combinations are considered the best option of care for patients with advanced nonsmall cell lung cancer (NSCLC), single-agent therapy is the preferred treatment for older patients. Since the late 1990s, various combinations of third-generation agents (gemcitabine [G], vinorelbine, ...

journal_title：Cancer

authors： Russo A,Rizzo S,Fulfaro F,Adamo V,Santini D,Vincenzi B,Gebbia N,Carreca I

更新日期：2009-05-01 00:00:00

abstract：:Two trials of leucovorin (LV) and 5-fluorouracil (5-FU) in patients with metastatic colorectal cancer were done, both using a 3-day loading dose and then weekly doses to minimize toxicity. The first trial used LV administered by intravenous infusion with a constant dose of 5-FU 400 mg/m2, and the second trail used ora...

journal_title：Cancer

authors： Laufman LR,Brenckman WD Jr,Stydnicki KA,Morgan ED,Collier M,Knick VB,Duch DS,Mullin R,Ferone R

更新日期：1989-03-15 00:00:00

abstract：BACKGROUND:The objective of this study was to establish the incidence and risk factors for the development of second solid cancers after allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:The authors reviewed the case files of 926 consecutive patients who underwent allo-HSCT at their institution b...

journal_title：Cancer

authors： Gallagher G,Forrest DL

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The value of surgical staging and treatment of the axillary lymph nodes with either surgery or radiotherapy in the initial management of patients with Stage I or II invasive breast cancer is controversial. METHODS:A review of retrospective and prospective clinical studies was performed to assess the risks o...

journal_title：Cancer

authors： Recht A,Houlihan MJ

更新日期：1995-11-01 00:00:00

abstract：:The individual medical histories in the files of the Oxford Record Linkage Study for the years 1963 to 1967 were analyzed to ascertain any previously unsuspected associations between cancers of the large bowel and other diseases in individuals, and to quantify the relative risks of disorders already known to be associ...

journal_title：Cancer

authors： Adelstein P,Baldwin JA,Fedrich J

更新日期：1979-06-01 00:00:00

abstract：:High calcitonin levels noted on a totally healthy 49-year-old man participating in a calcitonin control project led to a presumptive diagnosis of medullary carcinoma. Complete thyroid studies augmented by selective catheterization and quantitative calcitonin studies confirmed the clinical impression of medullary carci...

journal_title：Cancer

authors： White IL,Vimadalal SD,Catz B,Van de Velde R,LaGanga T

更新日期：1981-03-15 00:00:00

abstract：:Methionine-depleting total parenteral nutrition (methionine-depleting TPN), which infuses an amino acid solution devoid of L-methionine and L-cysteine as the sole protein source, showed enhancement of the effect of several anti-cancer agents. In this study, the combined effect of the methionine-depleting TPN with the ...

journal_title：Cancer

authors： Goseki N,Yamazaki S,Endo M,Onodera T,Kosaki G,Hibino Y,Kuwahata T

更新日期：1992-04-01 00:00:00

abstract：:In the past few years, the role of membrane-bound transport genes in human disease has been increasingly recognized and understood. Of these genes, the p170 membrane glycoprotein may function as an outward transport pump for many cancer chemotherapeutic drugs associated with the multidrug resistance phenotype. This ar...

journal_title：Cancer

authors： Leyland-Jones B,Dalton W,Fisher GA,Sikic BI

更新日期：1993-12-01 00:00:00

abstract：:The records of 314 children with acute lymphocytic leukemia (ALL) were reviewed to determine the frequency, clinical and laboratory features; contributing factors; and prognosis of cyclophosphamide-induced hemorrhagic cystitis. Twenty-five well-documented cases of hemorrhagic cystitis were identified. While most of th...

journal_title：Cancer

authors： Lawrence HJ,Simone J,Aur RJ

更新日期：1975-11-01 00:00:00

abstract：:The monitoring utility of serial patterns of a single marker (carcinoembryonic antigen) level and multiple marker (three carbohydrates-fucose, mannose and galactose) levels in patients with small cell carcinoma of the lung was investigated using a quantitative approach. A serial multiple regression (SMR) model was for...

journal_title：Cancer

authors： Woo KB,Waalkes P,Abeloff MD,Ettinger DS,McNitt KL,Gehrke CW

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Hepatic artery administration of iodine-131-Lipiodol serves as a modality that delivers targeted radiation therapy to hepatocellular carcinoma. Its efficacy has been promising according to trials conducted in the adjuvant setting after hepatic resection. Further investigation of its role in the palliative se...

journal_title：Cancer

authors： Chua TC,Chu F,Butler SP,Quinn RJ,Glenn D,Liauw W,Morris DL

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Estrogen receptor-alpha (ERalpha) is variably expressed in hepatocellular carcinoma (HCC) and is believed to be correlated with prognosis and survival. Recently, another estrogen receptor (ERbeta) has been identified, but its relevance in liver diseases is unknown. METHODS:The expression of ERbeta in the li...

journal_title：Cancer

authors： Iavarone M,Lampertico P,Seletti C,Francesca Donato M,Ronchi G,del Ninno E,Colombo M

更新日期：2003-08-01 00:00:00

abstract：:There are three principal disturbances in bone remodelling that occur in neoplasia affecting the skeleton. The first is an increase in bone turnover that in solid tumors may be confined to sites of metastases or be a generalized phenomenon, most likely related to the secretion of parathyroid hormone-related protein. I...

journal_title：Cancer

authors： Kanis JA,McCloskey EV

更新日期：1997-10-15 00:00:00

abstract：:The histologic findings of five patients with clinically typical Bowenoid dysplasia (BD) allowed the authors to classify the vulvar and perineal biopsies of 18 patients under 40 years as BD and the vulvar biopsies of six patients under 40 years as squamous cell carcinoma in situ (CIS). The two best criteria for BD are...

journal_title：Cancer

authors： Ulbright TM,Stehman FB,Roth LM,Ehrlich CE,Ransburg RC

更新日期：1982-12-15 00:00:00

abstract：:Clinical and pharmacokinetic studies were performed regarding the toxicity of methyl 6-[3-(2-chloroethyl)-3-nitrosoureido]-6-deoxy-alpha-D-glucopyranoside (MCNU) with other drugs, in conjunction with a peripheral blood stem cell autograft (PBSCT), for treating 26 children with acute leukemia or lymphoma associated wit...

journal_title：Cancer

authors： Takaue Y,Watanabe T,Hoshi Y,Abe T,Matsunaga K,Saito S,Hirao A,Kawano Y,Ninomiya T,Kuroda Y

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Synovial sarcoma usually arises in the extremities and in close proximity to large joints. Reported examples arising in the anterior abdominal wall are rare. Because most accounts from this location consist of case reports, neither clinical nor prognostic features have been well delineated. METHODS:Twenty-s...

journal_title：Cancer

authors： Fetsch JF,Meis JM

更新日期：1993-07-15 00:00:00

abstract：BACKGROUND:Skin cancer affects more Americans than any other type of cancer. Children are prime targets for prevention education, because sun overexposure in early childhood may affect the development of skin cancer later in life. Preventive behaviors adopted early in life may be less resistant to change than those acq...

journal_title：Cancer

authors： Loescher LJ,Buller MK,Buller DB,Emerson J,Taylor AM

更新日期：1995-01-15 00:00:00

abstract：:Forty-eight cases of primary insular carcinoid of the ovary were analyzed from a clinicopathologic viewpoint. Sixteen (33%) were associated with preoperative clinical evidence of the carcinoid syndrome. At operation only one ovary was usually enlarged, but in 16% the contralateral ovary was also enlarged by either a d...

journal_title：Cancer

authors： Robboy SJ,Norris HJ,Scully RE

更新日期：1975-08-01 00:00:00

abstract：:The Southwest Oncology Group in a prospective randomized study compared one year of adjuvant combination chemotherapy with continuous CMFVP to two years of intermittent L-PAM in women with operable breast cancer with histologically positive axillary lymph nodes. In fully evaluable patients with a 42-month median and 3...

journal_title：Cancer

authors： Glucksberg H,Rivkin SE,Rasmussen S,Tranum B,Gad-el-Mawla N,Costanzi J,Hoogstraten B,Athens J,Maloney T,McCracken J,Vaughn C

更新日期：1982-08-01 00:00:00

abstract：:The records of all 27 adult patients (age, greater than or equal to 16 years) diagnosed with cerebellar medulloblastoma between 1968 and 1986 were reviewed. Twenty-four patients (89%) were treated with postoperative megavoltage irradiation. Twenty of these patients underwent craniospinal irradiation. Sixteen patients ...

journal_title：Cancer

authors： Hazuka MB,DeBiose DA,Henderson RH,Kinzie JJ

更新日期：1992-04-15 00:00:00