Does endoscopic follow-up improve the outcome of patients with benign gastric ulcers and gastric cancer?

Abstract:

:This study investigated whether an endoscopic surveillance program for patients with "benign" gastric ulcers and gastric cancer leads to early detection of neoplasms and improves survival. The clinical course of all patients diagnosed between 1977 and 1986 as having either gastric ulcers or gastric cancer was followed for a minimum of 3 years. Of 597 patients with initially benign gastric ulcers, 452 (76%) returned for the recommended endoscopic follow-up examinations. In eight patients (1.8%), repeated biopsies disclosed malignant neoplasms; four of these patients (0.9%) had become asymptomatic. Survival curves were nearly identical in patients who complied and those who did not. Of 241 patients with gastric cancer, 72 underwent partial gastric resection with curative intent and survived the first year. Resectable cancer was detected in 5 of 48 patients who complied (10%); none of these patients died of cancer. However, 5-year actuarial survival rates were similar between the patients who complied and those who did not. Although endoscopic surveillance may detect resectable cancer in selected patients, it remains to be shown that such a strategy improves survival.

journal_name

Cancer

journal_title

Cancer

authors

Eckardt VF,Giessler W,Kanzler G,Bernhard G

doi

10.1002/1097-0142(19920115)69:2<301::aid-cncr28206

subject

Has Abstract

pub_date

1992-01-15 00:00:00

pages

301-5

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

69

pub_type

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