Abstract:
:Three cases of pulmonary lymphangiomyomatosis are described, with emphasis on the ultrastructural changes. The clinicopathologic features corresponded to those previously described. Each patient was a female in the reproductive years; breathlessness and recurrent pneumothoraces were the predominant clinical features. Histologically, the lungs showed a focal interstitial infiltrate of short, spindle-shaped mononuclear cells compatible with primitive smooth muscle, which was associated with irregular emphysema and hemosiderosis. Electron microscopy confirmed the smooth muscle nature of the pulmonary infiltrate and showed the presence of cells intermediate between smooth muscle and fibroblasts. Abnormalities were also noted in the pulmonary connective tissue that are possibly related to the fragility of the lung in this condition.
journal_name
Cancerjournal_title
Cancerauthors
Basset F,Soler P,Marsac J,Corrin Bdoi
10.1002/1097-0142(197612)38:6<2357::aid-cncr282038subject
Has Abstractpub_date
1976-12-01 00:00:00pages
2357-66issue
6eissn
0008-543Xissn
1097-0142journal_volume
38pub_type
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