Abstract:
:With increasing numbers of survivors from cancer at a young age, the issue of fertility preservation has assumed greater importance. This review describes normal ovarian and testicular function and summarizes what is known about the effect of chemotherapy and radiotherapy on the gonads and uterus. All young patients with cancer or leukemia should have their fertility prognosis discussed before the initiation of treatment. Sperm and embryo cryopreservation should be considered standard practice and be widely available for those at significant risk of infertility. For prepubertal girls, ovarian tissue cryopreservation should be considered if the risk of premature menopause is high, but for the prepubertal boy there are no established techniques in current practice.
journal_name
Cancerjournal_title
Cancerauthors
Wallace WHdoi
10.1002/cncr.26045subject
Has Abstractpub_date
2011-05-15 00:00:00pages
2301-10issue
10 Suppleissn
0008-543Xissn
1097-0142journal_volume
117pub_type
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