Absence of white matter changes on magnetic resonance imaging in children treated with CNS prophylaxis therapy for leukemia.

abstract：BACKGROUND:This study was conducted to review the efficacy and safety of oral bisphosphonates for the treatment of bone metastases in cancer patients. METHODS:Available published clinical studies of oral bisphosphonates in bone metastases from 1980 to the present were identified through a MEDLINE search and from liter...

journal_title：Cancer

authors： Major PP,Lipton A,Berenson J,Hortobagyi G

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The authors examined the "real-world" effectiveness of rituximab (R) maintenance therapy (R-maintenance) compared with observation after R-based induction therapy in patients with previously untreated follicular lymphoma (FL) in the United States. METHODS:The National LymphoCare Study is a prospective, mult...

journal_title：Cancer

authors： Nastoupil LJ,Sinha R,Byrtek M,Zhou X,Taylor MD,Friedberg JW,Link BK,Cerhan JR,Dawson K,Flowers CR

更新日期：2014-06-15 00:00:00

abstract：BACKGROUND:In the current study, the authors propose the quantitative Gleason score (qGS), a modification of the current Gleason grading system for prostate cancer, based on the weighted average of Gleason patterns present in the pathology specimen. They hypothesize that the qGS can improve prostate cancer risk stratif...

journal_title：Cancer

authors： Reese AC,Cowan JE,Brajtbord JS,Harris CR,Carroll PR,Cooperberg MR

更新日期：2012-12-15 00:00:00

abstract：BACKGROUND:Breast cancers that are negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) (triple negative [TN]) have been associated with high-grade histology, aggressive clinical behavior, and poor survival. It has been determined that breast cancers that ...

journal_title：Cancer

authors： Brown M,Tsodikov A,Bauer KR,Parise CA,Caggiano V

更新日期：2008-02-15 00:00:00

abstract：:Fifteen patients developed acute nonlymphocytic leukemia (ANLL) 31 to 182 months following chemotherapy and/or radiotherapy for various malignancies and one non-neoplastic disorder. The ANLL was commonly heralded by a brief preleukemic phase consisting of cytopenias and a variety of morphologic abnormalities. At diagn...

journal_title：Cancer

authors： Foucar K,McKenna RW,Bloomfield CD,Bowers TK,Brunning RD

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Mantle cell lymphoma (MCL) is an incurable B-cell malignancy, and patients with this disease have the poorest prognosis among all patients with B-cell lymphomas. The signaling pathways that trigger MCL escape from immune surveillance are unclear. Because Toll-like receptors (TLRs) initiate innate and adaptiv...

journal_title：Cancer

authors： Wang L,Zhao Y,Qian J,Sun L,Lu Y,Li H,Li Y,Yang J,Cai Z,Yi Q

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:DNA ploidy and S-phase fraction measured by DNA flow cytometry were shown to correlate with several clinicopathologic characteristics in several types of tumors. METHODS:DNA flow cytometry was performed on 329 samples (164 normal mucosa, 165 tumors) obtained from 165 patients (112 men) with stomach cancer, ...

journal_title：Cancer

authors： Lee KH,Lee JS,Suh C,Ahn MJ,Kim SW,Doh BS,Min YI,Kim BS,Park KC,Lee IC

更新日期：1993-09-15 00:00:00

abstract：:Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...

journal_title：Cancer

authors： Reddy S,Saxena VS,Hendrickson F,Deutsch W

更新日期：1981-02-15 00:00:00

abstract：BACKGROUND:Multiple cell-signaling ligands and receptors-including vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), endothelial growth factor (EGF), v-akt murine thymoma viral oncogene homolog (AKT), platelet-derived growth factor (PDGF), mitogen-activated protein kinase (MAPK), and 70-kilod...

journal_title：Cancer

authors： Abdeen A,Chou AJ,Healey JH,Khanna C,Osborne TS,Hewitt SM,Kim M,Wang D,Moody K,Gorlick R

更新日期：2009-11-15 00:00:00

abstract：BACKGROUND:Colonoscopic screening has increased detection of malignant colonic polyps (MPs). The goal of this study was to analyze trends and patterns in the surgical treatment of MPs and to assess outcomes as measured by lymph node retrieval and patient survival. METHODS:The Surveillance, Epidemiology, and End Result...

journal_title：Cancer

authors： Wasif N,Etzioni D,Maggard MA,Tomlinson JS,Ko CY

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The combination of a platinating agent and etoposide has induced responses in various pediatric tumors. The study estimated the maximum tolerated dose (MTD) of an oxaliplatin and etoposide regimen in children with recurrent solid tumors. METHODS:Oxaliplatin was administered on Day 1 and etoposide on Days 1 ...

journal_title：Cancer

authors： McGregor LM,Spunt SL,Santana VM,Stewart CF,Ward DA,Watkins A,Laningham FH,Ivy P,Furman WL,Fouladi M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Data suggest that vitamin D plays a role in the treatment and prevention of prostate cancer. The combination of high-dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) plus dexamethasone was studied based on evidence that dexamethasone potentiates the antitumor effects of calcitriol and ameliorates hyp...

journal_title：Cancer

authors： Trump DL,Potter DM,Muindi J,Brufsky A,Johnson CS

更新日期：2006-05-15 00:00:00

abstract：:The cellular DNA content in colorectal biopsies from 51 patients with chronic ulcerative colitis has been studied with flow-cytometric technique. The DNA pattern has been related to the duration of the disease, and to histopathology. Aneuploid cell lines were found in eight patients, two of which had histopathological...

journal_title：Cancer

authors： Hammarberg C,Slezak P,Tribukait B

更新日期：1984-01-15 00:00:00

abstract：:Although the existence of subclinical Pneumocystis carinii infection in pediatric patients with solid tumors or hematologic malignancies has been documented, similar data are lacking in adults. In addition, data are needed to define the epidemiology of this agent in adult malignancies to assess the validity of the met...

journal_title：Cancer

authors： Robert NJ,Pifer LL,Niell HB,Woods DR,Neely CL,Miller JH,Churchill H

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Breast reconstruction is performed with increasing frequency and has become important in the treatment of mastectomy patients. METHODS:The development of recurrent carcinoma after a mastectomy and transverse rectus abdominus myocutaneous (TRAM) flap procedure is described. RESULTS:The lesion was nonpalpabl...

journal_title：Cancer

authors： Mund DF,Wolfson P,Gorczyca DP,Fu YS,Love SM,Bassett LW

更新日期：1994-11-15 00:00:00

abstract：:Trichosporon cutaneum is a fungus known to cause superficial nodules over the distal third of hair shafts, mainly scalp hair, and to produce a clinical entity known as piedra. This superficial mycosis occurs mostly in temperate and tropical regions and is rarely seen in North America. Trichosporon cutaneum spesis is d...

journal_title：Cancer

authors： Rivera R,Cangir A

更新日期：1975-09-01 00:00:00

abstract：:Seventy-eight patients with disseminated testicular cancer were entered on a random prospective study evaluating three separate remission induction arms. Therapy with cis-diamminedichloroplatinum (20 mg/M2 for five consecutive days every three weeks for 3-4 courses) and bleomycin (30 units intravenous push weekly for ...

journal_title：Cancer

authors： Einhorn LH,Williams SD

更新日期：1980-09-15 00:00:00

abstract：BACKGROUND:A rigorous assessment of the risk of colorectal cancer (CRC) among prostate cancer (PC) survivors that controls for important confounding factors and competing risks is necessary to determine the risk of CRC in this population and to inform screening guidelines. METHODS:With data from Manitoba, Canada, subj...

journal_title：Cancer

authors： Desautels D,Czaykowski P,Nugent Z,Demers AA,Mahmud SM,Singh H

更新日期：2016-04-15 00:00:00

abstract：BACKGROUND:We sought to determine the impact of radical nephrectomy case volume, hospital size, and geographic region on immediate surgical outcomes for patients undergoing radical nephrectomy in academic centers across the country. METHODS:The University HealthSystem Consortium (UHC) Clinical Data Base was queried fo...

journal_title：Cancer

authors： Mitchell RE,Lee BT,Cookson MS,Barocas DA,Duke Herrell S,Clark PE,Smith JA,Chang SS

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Tamoxifen has been used in the treatment of patients with metastatic malignant melanoma either as a single agent or, more commonly, in combination with other chemotherapeutic agents. The aim of the current study was to summarize the available clinical evidence on the role of the tamoxifen in different combin...

journal_title：Cancer

authors： Lens MB,Reiman T,Husain AF

更新日期：2003-10-01 00:00:00

abstract：:The relative value of each lactic dehydrogenase isoenzyme (iso LDH) was measured by electrophoretic separation in the serum and the pleural fluid of 100 patients. In each case, the cause of the pleural effusion was known. Two types of LDH isoenzyme pattern were found in the serum: a normal type with a low value of LDH...

journal_title：Cancer

authors： Vergnon JM,Guidollet J,Gateau O,Ripoll JP,Collet P,Louisot P,Brune J

更新日期：1984-08-01 00:00:00

abstract：:A prospective randomized trial by CALGB examined the relative value of four chemotherapy regimens in 537 patients with stage III B and IV Hodgkin's disease. A new combination BOPP, derived by substitution of BCNU for nitrogen mustard in the MOPP regimen, was compared to MOPP and to two 3-drug regimens, derived by remo...

journal_title：Cancer

authors： Nissen NI,Pajak TF,Glidewell O,Pedersen-Bjergaard J,Stutzman L,Falkson G,Cuttner J,Blom J,Leone L,Sawitsky A,Coleman M,Haurani F,Spurr CL,Harley JB,Seligman B,Cornell C Jr,Henry P,Senn HJ,Brunner K,Martz G,Maurice

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:In addition to tumor thickness, several other prognostic parameters have been identified in primary human melanomas. Some are available readily (localization, gender, age, and ulceration). Others must be evaluated with a moderate or even substantial amount of work (mitoses and immunohistochemical markers). T...

journal_title：Cancer

authors： Ostmeier H,Fuchs B,Otto F,Mawick R,Lippold A,Krieg V,Suter L

更新日期：1999-06-01 00:00:00

abstract：:The validity of current staging systems for malignant melanoma was analyzed in a prospective study on 220 patients with extremity melanoma. Patients were followed 2 to 9 years after a wide excision of the primary, regional cytostatic perfusion and dissection of regional lymph nodes. The "original three-stage" system y...

journal_title：Cancer

authors： Ghussen F,Krüger I,Groth W

更新日期：1990-07-15 00:00:00

abstract：BACKGROUND:The term poorly differentiated (PD) carcinoma was proposed 20 years ago to define aggressive, follicular-derived thyroid carcinomas with behavior intermediate between follicular/papillary and anaplastic carcinomas. Among the variable histologic patterns recognized in such tumors, trabecular-insular-solid (TI...

journal_title：Cancer

authors： Volante M,Landolfi S,Chiusa L,Palestini N,Motta M,Codegone A,Torchio B,Papotti MG

更新日期：2004-03-01 00:00:00

abstract：:Ovarian, fallopian tube, and peritoneal cancers have a similar clinical presentation and are treated similarly, and current evidence supports staging all 3 cancers in a single system. The primary site (i.e. ovary, fallopian tube, or peritoneum) should be designated where possible. The histologic type should be recorde...

journal_title：Cancer

authors： Prat J,FIGO Committee on Gynecologic Oncology.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:BRAF inhibitors are effective in melanoma and other cancers with BRAF mutations; however, patients ultimately develop therapeutic resistance through the activation of alternative signaling pathways such as RAF/RAS or MET. The authors hypothesized that combining the BRAF inhibitor vemurafenib with either the ...

journal_title：Cancer

authors： Janku F,Sakamuri D,Kato S,Huang HJ,Call SG,Naing A,Holley VR,Patel SP,Amaria RN,Falchook GS,Piha-Paul SA,Zinner RG,Tsimberidou AM,Hong DS,Meric-Bernstam F

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Cervical cancer mortality rates have declined in the United States, primarily because of Papanicolaou testing. However, limited information is available about the incidence of the disease in the US-Mexico border region, where some of the poorest counties in the United States are located. This study was under...

journal_title：Cancer

authors： Coughlin SS,Richards TB,Nasseri K,Weiss NS,Wiggins CL,Saraiya M,Stinchcomb DG,Vensor VM,Nielson CM

更新日期：2008-11-15 00:00:00

abstract：BACKGROUND:Theoretical considerations have raised the suspicion that transurethral resection of the prostate (TURP) may increase the risk of developing prostate cancer in clinically benign prostate glands. Previous studies have not shown an increased risk among men who had undergone TURP for benign prostatic hyperplasi...

journal_title：Cancer

authors： Hammarsten J,Andersson S,Holmén A,Högstedt B,Peeker R

更新日期：1994-10-15 00:00:00

abstract：:Three patients with carcinoid tumors of the anterior mediastinum are described. Study of these patients and an analysis of previously reported cases indicates that the thymus is the primary site of these tumors, which are probably related to the presence of Kulchitsky cells in normal thymus. These neoplasms differ cli...

journal_title：Cancer

authors： Salyer WR,Salyer DC,Eggleston JC

更新日期：1976-02-01 00:00:00