Carcinoid tumors of the thymus.

Abstract:

:Three patients with carcinoid tumors of the anterior mediastinum are described. Study of these patients and an analysis of previously reported cases indicates that the thymus is the primary site of these tumors, which are probably related to the presence of Kulchitsky cells in normal thymus. These neoplasms differ clinically and anatomically from conventional thymomas. They occur predominantly in men, are not associated with myasthenia gravis or red-cell hypoplasia, and are more aggressive tumors than thymomas. Histologically, they are similar to carcinoid tumors of other organs and differ from the variable combination of epithelial cells and lymphocytes of thymomas. Although they are usually locally invasive and frequently metastasize, the clinical course is usually protracted. It is probable that the reported examples of Cushing's syndrome related to thymomas were actually associated with thymic carcinoid tumors.

journal_name

Cancer

journal_title

Cancer

authors

Salyer WR,Salyer DC,Eggleston JC

doi

10.1002/1097-0142(197602)37:2<958::aid-cncr2820370

subject

Has Abstract

pub_date

1976-02-01 00:00:00

pages

958-73

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

37

pub_type

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