Abstract:
:Whether malignant cells can be detected in the bowel movements induced by oral gut lavage solution administration was studied in patients with known colonic adenocarcinomas. The induced bowel movements were collected in 27 patients, nine of whom had cancer proven by anatomic pathologic examination. The cells present were recovered with a simple technique and stained by the Papanicolaou method. Malignant cells were identified in the stained preparations in all nine patients with cancer (100% sensitivity), and there were few false positives (94.5% specificity). The authors concluded that if additional studies with greater numbers of subjects confirm the reliability of this technique, a test may be developed that would be useful for either early detection or screening.
journal_name
Cancerjournal_title
Cancerauthors
Gordon IL,Rypins EB,Wuerker RB,Jakowatz JJdoi
10.1002/1097-0142(19910701)68:1<106::aid-cncr28206subject
Has Abstractpub_date
1991-07-01 00:00:00pages
106-10issue
1eissn
0008-543Xissn
1097-0142journal_volume
68pub_type
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