Effects of first-dose doxorubicin on cardiac rhythm as evaluated by continuous 24-hour monitoring.

abstract：BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...

journal_title：Cancer

authors： Mounier N,Morel P,Haioun C,Coiffier B,Tilly H,Chatelain C,Lederlin P,Thyss A,Herbrecht R,Gisselbrecht C,Lepage E

更新日期：1998-05-15 00:00:00

abstract：:A case of granulocytic sarcoma involving the uterine cervix as primary manifestation without evidence of leukemia is presented. It was followed by neurological symptoms 19 months later and a right breast mass 26 months after the initial cervical lesion, but still with no evidence of leukemia. Two years and four months...

journal_title：Cancer

authors： Seo IS,Hull MT,Pak HY

更新日期：1977-12-01 00:00:00

abstract：:Seventeen patients with adenocystic carcinoma have received 34 adequate trials of chemotherapy at Princess Margaret Hospital since 1969. There have been five objective responses to chemotherapy in 4 cases, lasting from five to 24 months, and 3 other patients have had stabilized disease for a period of five to seven mo...

journal_title：Cancer

authors： Tannock IF,Sutherland DJ

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to describe a population of young patients with breast carcinoma, their characteristics at the time of diagnosis, and the association of these characteristics with disease recurrence and survival. METHODS:Four hundred fifty-two women age < or = 35 years with breast carci...

journal_title：Cancer

authors： Gonzalez-Angulo AM,Broglio K,Kau SW,Eralp Y,Erlichman J,Valero V,Theriault R,Booser D,Buzdar AU,Hortobagyi GN,Arun B

更新日期：2005-06-15 00:00:00

abstract：:In January, 1972, the Southwest Oncology Group initiated two randomized studies for patients with advanced breast cancer. The study for patients with prior chemotherapy showed a 33% response rate with adriamycin. The study for patients without previous chemotherapy consisted of three treatment regimens; a weekly repea...

journal_title：Cancer

authors： Hoogstraten B,George SL,Samal B,Rivkin SE,Costanzi JJ,Bonnet JD,Thigpen T,Braine H

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Age-related disparities in colon cancer treatment exist, with older patients being less likely to receive recommended therapy. However, to the authors' knowledge, few studies to date have focused on receipt of surgery. The objective of the current study was to describe patterns of surgery in patients aged ≥ ...

journal_title：Cancer

authors： Neuman HB,O'Connor ES,Weiss J,Loconte NK,Greenblatt DY,Greenberg CC,Smith MA

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:After the introduction of a mammography screening program, the incidence of late-stage breast cancer is expected to decrease. The objective of the current study was to evaluate variations in the total incidence of breast cancer and in the incidence of breast cancers with a pathologic tumor (pT) classificatio...

journal_title：Cancer

authors： Foca F,Mancini S,Bucchi L,Puliti D,Zappa M,Naldoni C,Falcini F,Gambino ML,Piffer S,Sanoja Gonzalez ME,Stracci F,Zorzi M,Paci E,IMPACT Working Group.

更新日期：2013-06-01 00:00:00

abstract：:A case of a patient with a metastatic ACTH (adrenocorticotrophic hormone)-producing gastric carcinoid APUD (amine precursor uptake and decarboxylation) tumor is presented. The patient presented with Cushing's syndrome and very high levels of ACTH. The Cushing's syndrome was controlled medically, and when the patient d...

journal_title：Cancer

authors： Marcus FS,Friedman MA,Callen PW,Churg A,Harbour J

更新日期：1980-09-01 00:00:00

abstract：:A retrospective analysis of a series of 162 patients treated for isolated chest wall recurrence of breast cancer after mastectomy was undertaken. Cumulative survival, distant relapse-free survival, and freedom from local progression after 5 years from the diagnosis of recurrence were 34%, 28%, and 45% respectively. Fi...

journal_title：Cancer

authors： Magno L,Bignardi M,Micheletti E,Bardelli D,Plebani F

更新日期：1987-07-15 00:00:00

abstract：:A large lipoma and a large angiomyolipoma of the liver, one case each, are described. In the first case, a 24 X 14-cm homogeneous mass demonstrated a fatty density (-96H) on computed tomography (CT), echogenicity on sonography, and fine neovascular vessels on angiography in the right lobe of the liver. Histopathologic...

journal_title：Cancer

authors： Takayasu K,Shima Y,Muramatsu Y,Moriyama N,Yamada T,Makuuchi M,Hirohashi S

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Single-agent chemotherapy produces partial responses in the range of 7-27% in patients with Stage IV nonsmall cell lung carcinoma (NSCLC). Cisplatin-based combination regimens have achieved higher response rates but with significant toxicity. Two prior studies employing 24-hour infusions of paclitaxel showed...

journal_title：Cancer

authors： Tester WJ,Jin PY,Reardon DH,Cohn JB,Cohen MH

更新日期：1997-02-15 00:00:00

abstract：BACKGROUND:Because the prostatic capsule is often indistinct, recognition of extraprostatic extension by carcinoma depends heavily on the identification of carcinoma cells in the periprostatic adipose tissue. However, the distribution of adipose tissue along the prostatic surfaces has not been studied extensively. MET...

journal_title：Cancer

authors： Hong H,Koch MO,Foster RS,Bihrle R,Gardner TA,Fyffe J,Ulbright TM,Eble JN,Cheng L

更新日期：2003-04-01 00:00:00

abstract：:Demonstration of malignant cells in blood specimens collected during transurethral resection of the prostate (TURP) has implicated TURP in the dissemination of prostatic cancer. Of 153 patients who underwent radiation therapy for prostate cancer between January 1977 and June 1990 and were retrospectively analyzed, 93 ...

journal_title：Cancer

authors： Pansadoro V,Sternberg CN,DePaula F,Florio A,Giannarelli D,Arcangeli G

更新日期：1991-11-01 00:00:00

abstract：:The serious import of breast cancer lies in its potential for metastatic spread, which probably starts early in the course of the disease. Detection of the lesion when immunocompetence can control the metastases leads to long-term survival. This usually involves detection of unsuspected, preclinical disease. This is t...

journal_title：Cancer

authors： Strax P

更新日期：1984-02-01 00:00:00

abstract：:We report a case of inadvertent administration of over twice the usual dose of methyl-CCNU. The patient exhibited an early onset of bone marrow suppression. Profound pancytopenia, including lymphopenia, persisted for over seven weeks, Although early recovery started at about five weeks. Permanent marrow damage was ind...

journal_title：Cancer

authors： Breeden JH,Vollmer JT,Twomey PL

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND AND METHODS:A univariate and multivariate analysis for the correlation between histomorphologic factors and prognosis was made using data from 1116 patients with soft tissue sarcoma, including 1005 cases available with complete histologic and follow-up data. RESULTS:The overall 5-year survival rate was 43.6...

journal_title：Cancer

authors： Hashimoto H,Daimaru Y,Takeshita S,Tsuneyoshi M,Enjoji M

更新日期：1992-12-15 00:00:00

abstract：:Pain management often is difficult in patients with bone metastases. Metastatic disease represents >40% of oncologic practice, and >70% of patients with metastatic disease have uncontrolled cancer-related pain. Significant morbidity caused by pathologic fracture and spinal cord compression can result from untreated bo...

journal_title：Cancer

authors： Janjan NA

更新日期：1997-10-15 00:00:00

abstract：:Because of the rarity of the primary carcinoma of the female urethra, there has been limited experience of individual institutions in management of this disease. Treatment by radiation alone required radium implant skill in early cases and individualized consideration for integrating external and internal irradiation ...

journal_title：Cancer

authors： Prempree T,Wizenberg MJ,Scott RM

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Management of unresectable colorectal liver metastases (CLM) can be by regional (hepatic arterial infusion [HAI]) or systemic chemotherapy, or by symptom control alone. In this study the costs of each type of management were related to clinical outcome in 134 patients with CLM. METHODS:The costs (both in te...

journal_title：Cancer

authors： Durand-Zaleski I,Earlam S,Fordy C,Davies M,Allen-Mersh TG

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) develop central nervous system (CNS) progression or recurrence during the course of their disease. Patients with human immunodeficiency virus (HIV)-NHL often develop CNS progression despite the use of prophylaxis. Liposomal cytarabine (DepoCyte) has shown a...

journal_title：Cancer

authors： Spina M,Chimienti E,Martellotta F,Vaccher E,Berretta M,Zanet E,Lleshi A,Canzonieri V,Bulian P,Tirelli U

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:Although several refinements have been reported for breast magnetic resonance imaging (MRI), there has been no uniform agreement by researchers on the optimal method. The authors report a simple and effective MRI method that incorporated the best qualities of other breast MRI methods yet eliminated the compl...

journal_title：Cancer

authors： Khatri VP,Stuppino JJ,Espinosa MH,Pollack MS

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:It is hypothesized that oligometastatic disease represents a state of potentially curable, limited metastases. Stereotactic body radiation therapy (SBRT) is an option for patients who are not amenable to or do not want resection. METHODS:From 2001 to 2006, 121 patients with < or =5 detectable metastases wer...

journal_title：Cancer

authors： Milano MT,Katz AW,Muhs AG,Philip A,Buchholz DJ,Schell MC,Okunieff P

更新日期：2008-02-01 00:00:00

abstract：:Twenty-two patients with cancer of the colon and rectum were studied: preoperative and postoperative cell-mediated and humoral immune factors were assessed, and local concentration of immunoglobulins in tumor tissue and in normal mucosa were measured. Lymphocyte function was found to be reduced in 50% of stage A and B...

journal_title：Cancer

authors： Shafir M,Bekesi JG,Papatestas A,Slater G,Aufses AH Jr

更新日期：1980-08-15 00:00:00

abstract：BACKGROUND:Methotrexate is readily absorbed from the intestinal tract. When given to patients with urinary diversion to the intestinal tract, methotrexate may be reabsorbed into the circulation, thus increasing its serum concentration and potentially increasing its toxicity. METHODS:Forty-eight patients with transitio...

journal_title：Cancer

authors： Srinivas S,Mahalati K,Freiha FS

更新日期：1998-03-15 00:00:00

abstract：:Because chronic lymphocytic leukemia is a heterogeneous disease, there are considerable efforts underway to develop increasingly accurate and precise analytics with which to estimate the probability of future events such as the need for and probability of response to therapy, progression-free survival, and survival. T...

journal_title：Cancer

authors： Montserrat E,Gale RP

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Based on prior experience with dacarbazine (DTIC) and an outpatient interleukin-2 (IL-2) regimen, the current study was conducted to improve the antitumor efficacy and assess the immunologic interactions between chemotherapy and IL-2. METHODS:Thirty-two patients were registered onto a treatment program, whi...

journal_title：Cancer

authors： Flaherty LE,Robinson W,Redman BG,Gonzalez R,Martino S,Kraut M,Valdivieso M,Rudolph AR

更新日期：1993-06-01 00:00:00

abstract：:One-hundred and fifty-one adults with acute non-lymphocytic leukemia (ANLL) were entered into an Eastern Cooperative Oncology Group protocol (EST-1473) comparing twice daily cytosine arabinoside and thioguanine (AT) with weekly cyclophosphamide, cytosine arabinoside, and methotrexate (CAM) for remission induction. Of ...

journal_title：Cancer

authors： Skeel RT,Costello W,Bennett JM,Oken MM,Tobin MS,Bertino JR,Marsh JC,Carbone PP

更新日期：1980-01-15 00:00:00

abstract：:The antitumor effect of human leukocyte interferon was investigated on ten patients with malignant brain tumor. In eight cases of primary tumor, IFN alone was administered when their recurrent sign was evident. A dose of 3 X 10(6) IU or 1 X 10(6) IU of IFN was injected intramuscularly two or three times a week in high...

journal_title：Cancer

authors： Hirakawa K,Ueda S,Nakagawa Y,Suzuki K,Fukuma S,Kita M,Imanishi J,Kishida T

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Positron emission tomography (PET) with labeled fluorodeoxyglucose (FDG) demonstrates increased tracer uptake in many neoplasms. This study was undertaken to define the patterns of FDG uptake in head and neck neoplasms before and after high dose irradiation. METHODS:Twenty-five patients were evaluated prosp...

journal_title：Cancer

authors： Greven KM,Williams DW 3rd,Keyes JW Jr,McGuirt WF,Watson NE Jr,Randall ME,Raben M,Geisinger KR,Cappellari JO

更新日期：1994-08-15 00:00:00

abstract：BACKGROUND:African Americans are diagnosed more frequently with colorectal carcinoma at a later stage compared with Caucasians. One potential reason for the disparity is a lower rate of screening examinations. METHODS:Using Outpatient and Physician-Supplier claims for all Medicare beneficiaries age > or = 65 years in ...

journal_title：Cancer

authors： Cooper GS,Koroukian SM

更新日期：2004-01-15 00:00:00