Abstract:
BACKGROUND:African Americans are diagnosed more frequently with colorectal carcinoma at a later stage compared with Caucasians. One potential reason for the disparity is a lower rate of screening examinations. METHODS:Using Outpatient and Physician-Supplier claims for all Medicare beneficiaries age > or = 65 years in 1999, indications for fecal occult blood testing (FOBT), sigmoidoscopy, colonoscopy, and barium enema were divided into diagnostic, surveillance, or screening categories. Annualized rates were calculated based on the number of eligible fee-for-service months. RESULTS:Rates of FOBT (18.24% vs. 11.86%; P < 0.001) and sigmoidoscopy (3.07% vs. 2.17%; P < 0.001) were higher in Caucasians compared with African Americans, whereas rates of barium enema were higher in African Americans (2.26% vs. 1.88%; P < 0.001). Colonoscopy use was more frequent among men only in Caucasians compared with African-Americans (8.00% vs. 6.97%; P < 0.001). For FOBT, sigmoidoscopy, and colonoscopy, the racial differences in procedures performed for diagnostic purposes were of smaller magnitude than for screening; and, for colonoscopy, the use of diagnostic procedures actually was higher for African Americans. CONCLUSIONS:Racial disparities exist not only in the use of colorectal procedures but also in the indications for such testing, with African Americans less likely to undergo screening tests. The differences are consistent with delay in diagnosis until symptoms or signs develop and may contribute to disparities in cancer mortality.
journal_name
Cancerjournal_title
Cancerauthors
Cooper GS,Koroukian SMdoi
10.1002/cncr.20014subject
Has Abstractpub_date
2004-01-15 00:00:00pages
418-24issue
2eissn
0008-543Xissn
1097-0142journal_volume
100pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Virilizing adrenocortical tumors are uncommon in adult women. These lesions generally secrete dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS), but not testosterone, which usually is produced by ovarian tumors. Exceptionally, adrenal growths may give off testosterone and no other asse...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930915)72:6<1997::aid-cncr2820
更新日期:1993-09-15 00:00:00
abstract::Based on laboratory studies showing enhanced cytotoxicity of floxuridine (FUDR) when used with high doses of leucovorin (LV), a pilot study of FUDR and LV through an implantable pump was initiated for the treatment of hepatic metastases from colorectal cancer. The highest dose of LV that could be administered, taking ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900601)65:11<2446::aid-cncr282
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:Response rates in chronic myeloid leukemia (CML) are now reported based on the cumulative incidence of a single-time best response. The study aim was to examine the significance of different response criteria for CML on imatinib therapy. METHODS:In all, 276 patients with chronic phase CML on imatinib therap...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23238
更新日期:2008-02-15 00:00:00
abstract:METHODS:Three-hundred seventy patients with borderline tumors treated between 1970 and 1982 at the Norwegian Radium Hospital were analyzed retrospectively for clinicopathologic features, treatment, and survival characteristics. RESULTS:One hundred seventy-eight patients had mucinous tumors, 174 patients had serous tum...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930301)71:5<1810::aid-cncr2820
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Conditional survival is clinically useful, particularly for patients with malignant disease who have a poor prognosis. However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis. METHODS:Data on 217,573 patients with breast, colorectal, ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20011015)92:8<2211::aid-cncr1565
更新日期:2001-10-15 00:00:00
abstract:BACKGROUND:The diagnosis of melanomas at an early stage is associated with improved survival, so the recognition of changes in pigmented skin lesions over time is important. We have developed a computer imaging system with the aim of assisting clinicians in differentiating early melanomas from benign pigmented skin les...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960715)78:2<252::AID-CNC
更新日期:1996-07-15 00:00:00
abstract::A leukocyte migration procedure was utilized to test cellular hypersensitivity of breast cancer patients' leukocytes to autologous and homologous breast cancer tissues and to murine milk containing murine mammary tumor virus (MuMTV). The in vitro responsiveness of the leukocytes and the antigenicity of breast cancer t...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197501)35:1<121::aid-cncr2820350
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:In animal models carbogen (normobaric 95% oxygen, 5% carbon dioxide) provides significant enhancement of local tumor control with fractionated radiotherapy. This approach to radiosensitization has been evaluated in the treatment of patients with bladder carcinoma using radical radiotherapy. METHODS:Sixty-on...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:Metastatic renal cell cancer is associated with poor long-term survival and has no cure. Traditional clinical endpoints are best supplemented by patient-reported outcomes designed to assess symptoms and function. Normative data was obtained on the National Comprehensive Cancer Network-Functional Assessment o...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27688
更新日期:2013-01-15 00:00:00
abstract:BACKGROUND:Leptomeningeal carcinomatosis (LC) represents a devastating complication of systemic cancer, and patients with LC have a dismal prognosis and increased mortality. The few studies that have focused on the evaluation of prognostic factors in patients with LC have resulted in contradictory results. Thus, the tr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24041
更新日期:2009-01-15 00:00:00
abstract::A 42-year-old woman developed lower extremity weakness and sensory loss 1 year after external and intracavitary radiotherapy for Stage IB carcinoma of cervix. She has been followed for 5 years posttreatment, and the neurologic abnormalities have persisted, but no evidence of recurrent carcinoma has been found. We beli...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19901001)66:7<1488::aid-cncr2820
更新日期:1990-10-01 00:00:00
abstract:BACKGROUND:The objective of this study was to discover molecular biomarkers associated with the recurrence of esophageal squamous cell carcinoma (ESCC). METHODS:The authors retrospectively analyzed the hypermethylation status of 11 genes using methylation-specific polymerase chain reaction (PCR) and the expression of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27948
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Only five cases of basaloid squamous cell carcinoma (BSCC), a rare tumor of head and neck, have been reported to involve the floor of mouth. METHODS:Clinicopathologic and immunohistochemical features of eight BSCC of floor of mouth were studied to evaluate the significance of the basaloid features. RESULTS...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931015)72:8<2299::aid-cncr2820
更新日期:1993-10-15 00:00:00
abstract:BACKGROUND:Patients with prostate cancer receiving androgen deprivation therapy (ADT) are at risk of sleep disturbance; however, to the authors' knowledge, the mechanisms by which ADT may affect sleep are not well understood. The current study compared objective and subjective sleep disturbance in ADT recipients and co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31024
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Helicobacter pylori recently was identified as a risk factor for gastric cancer. Its association with preneoplastic conditions of the stomach, however, is undocumented. METHODS:Gastric biopsy specimens from 245 symptomatic patients were examined for neoplastic and preneoplastic lesions and for gastric H. py...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930115)71:2<297::aid-cncr28207
更新日期:1993-01-15 00:00:00
abstract:BACKGROUND:Recently, the authors identified molecular signatures and pathways associated with nonsmall cell lung carcinoma histology and lung development. They hypothesized that genetic classifiers of histology would provide insight into lung tumorigenesis and would be associated with clinical outcome when evaluated in...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20542
更新日期:2004-10-01 00:00:00
abstract::A case of squamous cell carcinoma of the tongue in a 26-year-old man developing nine years after renal transplantation is presented. This is the first such case to be reported. Within seven months, widespread tumor metastases resulted in death. Pathologic examination of the transplanted kidney demonstrated neither re-...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197801)41:1<1::aid-cncr282041010
更新日期:1978-01-01 00:00:00
abstract::A previously unreported high incidence of endoscopically identifiable, diffuse, largely nonulcerative esophagitis, is described in a selected population of Southern African blacks at risk of cancer of the esophagus. This is comparable with findings in similar groups in Iran and China. The incidence of dysplasia and "e...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860601)57:11<2222::aid-cncr282
更新日期:1986-06-01 00:00:00
abstract:BACKGROUND:Recent clinical trials support adding ovarian suppression (OS) to oral endocrine therapy (ET) for premenopausal women with early breast cancer. The adoption of OS among real-world populations and the impact of OS on ET adherence have not been evaluated. METHODS:This study examined a retrospective, observati...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33367
更新日期:2021-01-28 00:00:00
abstract::The unusual genetic disorder epidermolysis bullosa dystrophica has been reported in several patients in whom the chronic cutaneous scars led to the development of cutaneous squamous cell carcinoma. However, only one of these previously reported cases involved the autosomal dominant form of the disease; the remainder o...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810201)47:3<615::aid-cncr28204
更新日期:1981-02-01 00:00:00
abstract::Adenoid cystic carcinoma of the esophagus is a relatively rare lesion which characteristically exhibits a clinically aggressive behavior. In spite of this aggressive nature, it is most often referred to as a counterpart of the more common adenoid cystic carcinoma of salivary gland origin, a comparatively indolent tumo...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19840301)53:5<1131::aid-cncr2820
更新日期:1984-03-01 00:00:00
abstract:BACKGROUND:Neovascularization reportedly is correlated with metastasis, recurrence, and prognosis in some types of tumors. Microvessel quantification in so-called "hot spots" has been studied extensively as the only factor reflecting angiogenesis in various malignant tumors. The objective of this report was to evaluate...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-11-15 00:00:00
abstract::CA 125 and steroid production is compared in a group of 48 women with ovarian epithelial carcinoma. The histologic types were I C (n = 20), II C (n = 5), III C (n = 11), or V (n = 12). The number of patients in Stage I was six; Stage II, 11; Stage III, 16; and Stage IV, 15. All patients were naturally or surgically po...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900501)65:9<2058::aid-cncr2820
更新日期:1990-05-01 00:00:00
abstract:BACKGROUND:Antithymocyte globulin (ATG) is an important component of conditioning regimens to prevent severe graft-versus-host disease (GVHD) in patients undergoing unmanipulated, haploidentical stem cell transplantation (haplo-SCT). However, to the authors' knowledge, the optimal dose of ATG is unknown. METHODS:In th...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.30540
更新日期:2017-08-01 00:00:00
abstract::Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19901215)66:12<2498::aid-cncr282
更新日期:1990-12-15 00:00:00
abstract::Twenty-four women with ovarian carcinoma that had metastasized to the liver were treated with intrahepatic infusional therapy. No consistent drug regimen was used. There were no complete responders; however, 33% had a partial response. All responses were noticed after the first course of therapy. The median length of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870601)59:11<1866::aid-cncr282
更新日期:1987-06-01 00:00:00
abstract:BACKGROUND:Febrile neutropenia (FN) is a serious and potentially life-threatening condition that may develop in patients with cancer who receive myelosuppressive chemotherapy. The risk of mortality from FN is not well characterized in current clinical practice. METHODS:Patients with cancer who were receiving chemother...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25332
更新日期:2010-12-01 00:00:00
abstract::Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860715)58:2+<461::aid-cncr2820
更新日期:1986-07-15 00:00:00
abstract::The cytologic results of 34 fine-needle aspiration (FNA) biopsies of the central nervous system (CNS) are reported. There were 31 intraoperative biopsies performed at the time of craniotomy. All the cases were diagnosed using direct smear preparations stained with Papanicolaou and Diff-Quik (Harleco, NJ) stains. The s...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860901)58:5<1117::aid-cncr2820
更新日期:1986-09-01 00:00:00
abstract:BACKGROUND:Patients with basal cell carcinoma (BCC) demonstrate marked variation in clinical phenotype, suggesting the presence of distinct subgroups. Patients with truncal lesions comprise an interesting subgroup, because, although the pathogenesis of these tumors is unclear, there is evidence to suggest that their de...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010715)92:2<354::aid-cncr1330>
更新日期:2001-07-15 00:00:00