Cytogenetic and molecular responses and outcome in chronic myelogenous leukemia: need for new response definitions?

abstract：:The livers of 345 autopsy cases of chronic liver disease were examined for macroregenerative nodule (MRN), a large nodular lesion more than 10 mm in diameter. A total of 86 lesions of MRN was found in 49 cases (14.2%): 32 were from 191 cases of hepatocellular carcinoma (HCC), 16 were from 148 cases of cirrhosis only, ...

journal_title：Cancer

authors： Furuya K,Nakamura M,Yamamoto Y,Togei K,Otsuka H

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Two pancreatic cancer cell lines, the highly invasive and metastatic cell line PC-1.0 and the weakly invasive and rarely metastatic cell line PC-1, were established from a pancreatic ductal carcinoma induced by N-nitrosobis (2-oxopropyl) amine in a Syrian golden hamster. METHODS:The cancer cell dissociation...

journal_title：Cancer

authors： Kurizaki T,Egami H,Hirota M,Akagi J,Ohmachi H,Yamamoto S,Ogawa M

更新日期：1995-03-15 00:00:00

abstract：:Reported is the case of a 24-year-old white man with inoperable giant cell carcinoma of the thyroid who achieved tumor regression following therapy with bleomycin, Adriamycin and cisplatinum. After 2 courses of chemotherapy, the tumor was deemed operable, and the patient underwent total thyroidectomy followed by radia...

journal_title：Cancer

authors： Spanos GA,WolK D,Desner MR,Khan A,Platt N,Khafif RA,Cortes EP

更新日期：1982-12-01 00:00:00

abstract：:Chromosome abnormalities from 17 malignancies that were studied using direct preparations and G-, Q-, and C-banding methods are presented and the findings assessed. The material used was from 6 primary cervical carcinomas, 5 primary and metastatic ovarian carcinomas and 6 other metastatic carcinomas. In general, chrom...

journal_title：Cancer

authors： van der Riet-Fox MF,Retief AE,van Niekerk WA

更新日期：1979-12-01 00:00:00

abstract：:Twenty of 391 newly diagnosed cases of prostatic cancer (5%) had a prior prostatectomy for benign disease. Digital rectal examination in 16 of 19 patients (84%) revealed a significant prostatic abnormality. Continued serial digital rectal examination should be performed routinely after prostatectomy for benign disease...

journal_title：Cancer

authors： Schwartz I,Wein AJ,Malloy TR,Glick JH

更新日期：1986-08-15 00:00:00

abstract：:Flow cytometry was used to compare binding of wheat germ agglutinin (WGA) and Lens culinaris lectin (Lcl) to peripheral lymphocytes (PBL) from normal subjects and 26 patients with chronic lymphocytic leukemia (CLL). As defined by the interactions of WGA and Lcl with cell surface receptors, normal unfractionated PBL an...

journal_title：Cancer

authors： Boldt DH,Nelson MO

更新日期：1983-06-01 00:00:00

abstract：:Breast reconstruction is not a new idea. Techniques have been developing since the late 1800s. The state of the art is such that the knowledge of its availability and success has significant effect on the willingness of women to seek earlier diagnosis and treatment. However, reconstruction is not for everyone. This pa...

journal_title：Cancer

authors： Brown HG

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Interleukin-18 (IL-18) is a novel immunoregulatory cytokine that was known previously as interferon-gamma-inducing factor. IL-18 levels can be used as a serum indicator for monitoring the clinical course of patients with hematologic malignancies and gastric carcinoma. Nitric oxide (NO) is a pleiotropic molec...

journal_title：Cancer

authors： Günel N,Coşkun U,Sancak B,Günel U,Hasdemir O,Bozkurt S

更新日期：2002-08-01 00:00:00

abstract：:Plasminogen activator is a serine protease which exists in two forms, known as tissue-type plasminogen activator and urokinase-type plasminogen activator. Here, we show that urokinase-type plasminogen activator activity in primary breast carcinomas correlates with both size of tumor and number of axillary nodes with m...

journal_title：Cancer

authors： Duffy MJ,O'Grady P,Devaney D,O'Siorain L,Fennelly JJ,Lijnen HJ

更新日期：1988-08-01 00:00:00

abstract：:A 21-year-old patient, after radiation therapy to the mediastinum for Hodgkin's disease, died six years later of a spinal cord glioma, believed to be caused by irradiation therapy. That the x-ray therapy provoked neoplastic changes seems likely, although it could be coincidental. ...

journal_title：Cancer

authors： Clifton MD,Amromin GD,Perry MC,Abadir R,Watts C,Levy N

更新日期：1980-04-15 00:00:00

abstract：:A retrospective study was made of the surgical treatment of distant metastases from melanoma in 143 patients. The determinants of survival benefit were: (1) successful complete resection of all clinical disease; (2) single versus multiple metastatic site; and (3) anatomic location of disease. Complete resection was ac...

journal_title：Cancer

authors： Overett TK,Shiu MH

更新日期：1985-09-01 00:00:00

abstract：:Treatment of 91 consecutive patients having metastatic, Stage IV melanoma who had not received any previous chemotherapy was begun between January 1977 and April 1978. The therapy included bleomycin (B) at 7.5 units subcutaneously in the first course and 15 units in subsequent courses on days 1 and 4; vincristine or O...

journal_title：Cancer

authors： Seigler HF,Lucas VS Jr,Pickett NJ,Huang AT

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:RUNX3 is a tumor suppressor that plays important roles in cell proliferation, apoptosis, and metastasis. The authors investigated the role of RUNX3 in melanoma pathogenesis and analyzed the prognostic impact of RUNX3 expression in a large series of melanoma patients. METHODS:Two sets of tissue microarrays w...

journal_title：Cancer

authors： Zhang Z,Chen G,Cheng Y,Martinka M,Li G

更新日期：2011-06-15 00:00:00

abstract：:This report is based on 903 patients with resections for gastric carcinoma between October 1957, and July 1969, entered in controlled trials of adjuvant therapy with Thio-TEPA and FUDR. Neither Thio-TEPA nor FUDR, as administered, prolonged survival. The extent of disease at the time of curative surgery is related to ...

journal_title：Cancer

authors： Serlin O,Keehn RJ,Higgins GA Jr,Harrower HW,Mendeloff GL

更新日期：1977-09-01 00:00:00

abstract：:Only three previous reports on the ultrastructural appearance of tibial adamantinoma have been found among some 120 cases of this tumor reported in the literature. The tumor in our case is less differentiated than the cases previously reported. We believe it is of epithelial character and the possibilities of its hist...

journal_title：Cancer

authors： Yoneyama T,Winter WG,Milsow L

更新日期：1977-09-01 00:00:00

abstract：:This study defines, by morphometric analysis, criteria for the diagnosis of ovarian dysplasia. Areas of surface epithelium, adjacent to Stage I ovarian serous papillary adenocarcinoma, were diagnosed as dysplastic and evaluated for architectural and cytologic changes by means of two specially designed interactive morp...

journal_title：Cancer

authors： Deligdisch L,Gil J

更新日期：1989-02-15 00:00:00

abstract：:Image cytometry for the classification of fine needle aspirate (FNA) biopsies was evaluated in samples from 39 women. Eighteen of them had benign lesions, seven had premalignant lesions, nine had carcinoma in situ, and five had carcinoma. The term, premalignant, here refers to lesions with an increased risk of develop...

journal_title：Cancer

authors： King EB,Chew KL,Duarte L,Hom JD,Mayall BH,Miller TR,Petrakis NL

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that multiple cytokines are secreted by ovarian epithelial cancer cells. Previous studies have shown that the cancer cell lines secrete macrophage colony-stimulating factor (M-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-1 (IL-1), interleukin-6 (IL-6)...

journal_title：Cancer

authors： Moradi MM,Carson LF,Weinberg B,Haney AF,Twiggs LB,Ramakrishnan S

更新日期：1993-10-15 00:00:00

abstract：:Formal cancer survivorship care is a growing focus internationally. This article provides a broad overview of the national strategies currently in progress for the development of survivorship programs and care plans within the United States and across Europe. The different approaches taken in their implementation, sta...

journal_title：Cancer

authors： McCabe MS,Faithfull S,Makin W,Wengstrom Y

更新日期：2013-06-01 00:00:00

abstract：:Our simple rapid autoradiography for 3H-thymidine (3H-TdR) labeling index (LI) of leukemic cells was introduced. Thirty-nine adult patients with acute nonlymphocytic leukemia were treated under a new protocol using 3H-TdR LI as a parameter and inserting a trial of partial synchronization by Ara-C. The success rate of ...

journal_title：Cancer

authors： Yoshida T,Hattori KI,Nakamura S,Mitamura E,Kobayashi S,Ohtake S,Tanimoto K

更新日期：1980-11-15 00:00:00

abstract：:In Finland, the incidence of cervical cancer has shown a decreasing tendency since the 1960s. The same trend, however, has not been noticed in the incidence of cervical adenocarcinoma. The reason for this is not known, although many studies have shown differences in the cause, epidemiology, and biology of the epidermo...

journal_title：Cancer

authors： Leminen A,Paavonen J,Forss M,Wahlström T,Vesterinen E

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The poor prognosis reported for patients with high-grade glial neoplasms indicates a need for the development of multimodality therapeutic approaches. The addition of chemotherapy has contributed variably to increased survival. The objective of the current study (Southwest Oncology Group [SWOG] 9016) was to ...

journal_title：Cancer

authors： Blumenthal DT,Rankin C,Eyre HJ,Livingston RB,Spence AM,Stelzer KJ,Rushing EJ,Berger MS,Rivkin SE,Cohn AL,Petersdorf SH

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:In light of the steadily improving capability to treat opportunistic infections, the authors reviewed their recent experience with short course empiric radiotherapy for the treatment of human immunodeficiency virus (HIV)-associated presumed central nervous system (CNS) lymphoma. METHODS:Medical records were...

journal_title：Cancer

authors： Donahue BR,Sullivan JW,Cooper JS

更新日期：1995-07-15 00:00:00

abstract：:Four cases of non-Hodgkin's lymphoma (NHL) limited to the larynx are described. All were diffuse, high-grade, B-cell lymphomas of large lymphoid cell type (three centroblastic and one immunoblastic). Immunocytochemistry was performed on three cases; two showed monoclonal cytoplasmic immunoglobulin and one showed monoc...

journal_title：Cancer

authors： Morgan K,MacLennan KA,Narula A,Bradley PJ,Morgan DA

更新日期：1989-09-01 00:00:00

abstract：:This clinicopathologic study concerns 27 cases of "dedifferentiated" soft tissue sarcoma (DSTS), including 14 liposarcomas, six leiomyosarcomas, five chondrosarcomas, and two rhabdomyosarcomas. In addition, the authors conducted an immunohistochemical survey of 23 cases and an electron microscopic examination of three...

journal_title：Cancer

authors： Hashimoto H,Daimaru Y,Tsuneyoshi M,Enjoji M

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Kaiser Permanente (KP) is a large health maintenance organization (HMO) operating in 14 states and caring for 8,000,000 members in hundreds of facilities staffed by thousands of physicians and support personnel. Cancer care is provided to these KP members as part of the health care package. METHODS:KP insur...

journal_title：Cancer

authors： Glass A

更新日期：1998-05-15 00:00:00

abstract：BACKGROUND:Two evidence-based therapies exist for the treatment of high-risk prostate cancer (PCA): external-beam radiotherapy (RT) with hormone therapy (H) (RT + H) and radical prostatectomy (S) with adjuvant radiotherapy (S + RT). Each of these strategies is associated with different rates of local control, distant m...

journal_title：Cancer

authors： Parikh R,Sher DJ

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Children with average-risk acute lymphoblastic leukemia (AR-ALL) face many challenges that can adversely affect their quality of life (QOL). However, to the authors' knowledge, patterns and predictors of QOL impairment during therapy have not been well characterized to date. METHODS:Patients with AR-ALL who...

journal_title：Cancer

authors： Zheng DJ,Lu X,Schore RJ,Balsamo L,Devidas M,Winick NJ,Raetz EA,Loh ML,Carroll WL,Sung L,Hunger SP,Angiolillo AL,Kadan-Lottick NS

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:In the current study, the authors propose the quantitative Gleason score (qGS), a modification of the current Gleason grading system for prostate cancer, based on the weighted average of Gleason patterns present in the pathology specimen. They hypothesize that the qGS can improve prostate cancer risk stratif...

journal_title：Cancer

authors： Reese AC,Cowan JE,Brajtbord JS,Harris CR,Carroll PR,Cooperberg MR

更新日期：2012-12-15 00:00:00

abstract：:This report describes a patient referred at 14 years in 1971, after one year's surveillance by the family physician, for a persistently elevated erythrocyte sedimentation rate, leukopenia, and relative lymphocytosis. Despite the documented myeloproliferative syndrome of seven years, significant physiologic impairment ...

journal_title：Cancer

authors： Whaun JM,Lin CC,Biederman B,Cornish SJ,Dundas JB

更新日期：1981-09-01 00:00:00