External beam irradiation and the combination of cisplatin and carmustine followed by carmustine alone for the treatment of high-grade glioma: a phase 2 Southwest Oncology Group trial.

abstract：:Sequential corrected creatinine clearance (CCC) evaluations were obtained in 30 patients treated with intra-arterial and/or intravenous cis-diamminedichloroplatinum-II (CDP). The dose was 150 mg/M2 administered with mannitol diuresis at 2 to 3 weekly intervals. Four hundred fifty-three courses were administered (range...

journal_title：Cancer

authors： Jaffe N,Keifer R 3rd,Robertson R,Cangir A,Wang A

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Several pathologic staging systems for malignant pleural mesothelioma (MPM) have been published, but none of them provide optimal survival stratification or stage distribution among patients treated with surgery. Interpretation of prior studies that correlate pathologic factors with outcome has been confound...

journal_title：Cancer

authors： Richards WG,Godleski JJ,Yeap BY,Corson JM,Chirieac LR,Zellos L,Mujoomdar A,Jaklitsch MT,Bueno R,Sugarbaker DJ

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:Small cell glioblastoma (GBM) is a variant with monomorphous, deceptively bland nuclei that often is misdiagnosed as anaplastic oligodendroglioma. METHODS:To elucidate its clinicopathologic and genetic features, the authors studied 71 adult patients (median age, 57 years), including 22 patients who were ide...

journal_title：Cancer

authors： Perry A,Aldape KD,George DH,Burger PC

更新日期：2004-11-15 00:00:00

abstract：:In an Easter Cooperative Oncology Group trial, Cytoxan-prednisone (CP) Induction was compared to BCNU-prednisone (BP) in 273 patients with lymphocytic lymphoma. Response rates were comparable, with 21% achieving complete response and 40%, partial response. Patients with a nodular pattern responded better. Maintenance ...

journal_title：Cancer

authors： Ezdinli E,Pocock S,Berard CW,Aungst CW,Silverstein M,Horton J,Bennett J,Bakemeier R,Stolbach L,Perlia C,Brunk SF,Lenhard RE,Klaassen DJ,Richter P,Carbone P

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:As increasing numbers of young patients with cancer survive, interest in the late effects of therapy is rising. METHODS:The sequelae of treatment were reviewed after a minimum of 5 years of observation in 109 surviving patients with sarcoma of the bladder or prostate who were enrolled in the Intergroup Rhab...

journal_title：Cancer

authors： Raney B Jr,Heyn R,Hays DM,Tefft M,Newton WA Jr,Wharam M,Vassilopoulou-Sellin R,Maurer HM

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Current salvage therapy for recurrent high-risk neuroblastoma is rarely curative. Assessment of the effectiveness of new, primarily cytostatic agents requires the redefinition of study endpoints to reflect disease stabilization rather than tumor response or regression. The intervals of disease control in the...

journal_title：Cancer

authors： Santana VM,Furman WL,McGregor LM,Billups CA

更新日期：2008-06-15 00:00:00

abstract：:Seventeen patients were given DTIC, 200 mg/m2/day in five-day courses every four to six weeks. In four patients (stage II) treated on an adjuvant basis, tumor recurrence has been verified in three. Four of the palliatively treated patients were also given DTIC by regional intra-arterial infusion with minimal positive ...

journal_title：Cancer

authors： Jönsson PE,Agrup G,Arnbjörnsson E,Hafström L,Rorsman H

更新日期：1980-01-15 00:00:00

abstract：:A case of Turcot's syndrome (colonic polyposis plus a malignant central nervous system tumor) occurring in a kindred with autosomal dominant colonic polyposis is presented. It is proposed that Turcot's syndrome patients can be classified into Type I where only siblings are affected and Type II where two or more genera...

journal_title：Cancer

authors： Lewis JH,Ginsberg AL,Toomey KE

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:The objectives of this study were to investigate outcome prediction by measuring absolute tumor volume and regression ratios using serial magnetic resonance imaging (MRI) during radiation therapy (RT) for cervical cancer and to develop algorithms capable of identifying patients at risk of a poor therapeutic ...

journal_title：Cancer

authors： Wang JZ,Mayr NA,Zhang D,Li K,Grecula JC,Montebello JF,Lo SS,Yuh WT

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The current study was conducted to expedite international standardized reporting of bone marrow disease in children with neuroblastoma and to improve equivalence of care. METHODS:A multidisciplinary International Neuroblastoma Response Criteria Bone Marrow Working Group was convened by the US National Cance...

journal_title：Cancer

authors： Burchill SA,Beiske K,Shimada H,Ambros PF,Seeger R,Tytgat GA,Brock PR,Haber M,Park JR,Berthold F

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Karyotypic abnormalities in sporadic Burkitt lymphoma (BL) have been described extensively. However, to the authors' knowledge, very limited studies have focused on the secondary chromosomal abnormalities in pediatric BL as compared with those of adult BL and on their prognostic impact. METHODS:A retrospect...

journal_title：Cancer

authors： Onciu M,Schlette E,Zhou Y,Raimondi SC,Giles FJ,Kantarjian HM,Medeiros LJ,Ribeiro RC,Pui CH,Sandlund JT

更新日期：2006-09-01 00:00:00

abstract：:A previously unreported association of Brenner and adenomatoid tumor found in the tunica vaginalis testis is presented. Many ultrastructural features found in mesothelial cells such as intercellular spaces, deeply indented nuclei, tonofilaments and tight desmosomes, were also shared by cells present in both neoplastic...

journal_title：Cancer

authors： Nogales FF Jr,Matilla A,Ortega I,Alvarez T

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:The reliability of fine-needle aspiration cytology (FNAC) of breast masses in males could be compromised by lack of experience because breast carcinoma is rare in males and FNAC is not often used. In addition, FNAC of the more often encountered gynecomastia may lead to overdiagnosis. Therefore, in the curren...

journal_title：Cancer

authors： Westenend PJ,Jobse C

更新日期：2002-04-25 00:00:00

abstract：BACKGROUND:Although almost half of all incidents of breast carcinoma occur in women age > or = 65 years, not enough is known about appropriate care for patients in this age group. The objective of the current study was to evaluate the role of breast conservation therapy in the management of breast carcinoma in women ag...

journal_title：Cancer

authors： Vlastos G,Mirza NQ,Meric F,Hunt KK,Kuerer HM,Ames FC,Ross MI,Buchholz TA,Hortobagyi GN,Singletary SE

更新日期：2001-09-01 00:00:00

abstract：:The European Organization for Research on Treatment of Cancer (EORTC) trial 20781, concerning osteosarcoma of the limbs is reported. After definitive treatment of the primary tumor with amputation or irradiation, adjuvant treatment was given, randomized into either 9 months of chemotherapy according to a modified Rose...

journal_title：Cancer

authors： Burgers JM,van Glabbeke M,Busson A,Cohen P,Mazabraud AR,Abbatucci JS,Kalifa C,Tubiana M,Lemerle JS,Voûte PA

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:This study explores whether externalizing religious and spiritual beliefs is associated with advanced-stage colon cancer at initial oncology presentation and whether this association is stronger for blacks than for whites. METHODS:Patients who had newly diagnosed, invasive colon cancer were recruited at 9 s...

journal_title：Cancer

authors： Polite BN,Cipriano-Steffens TM,Hlubocky FJ,Jean-Pierre P,Cheng Y,Brewer KC,Rauscher GH,Fitchett GA

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the significance of tumor angiogenesis and angiogenic factors such as hepatocyte growth factor (HGF) and c-Met in determining the prognoses of 93 patients with endometrial carcinoma. METHODS:By immunohistochemical staining, this retrospective study investigated tumor angi...

journal_title：Cancer

authors： Wagatsuma S,Konno R,Sato S,Yajima A

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Chemotherapy is known to cure a small minority of patients with acute myeloid leukemia (AML). Less is known about the risk of such patients developing subsequent cancers or about their ability to return to work. METHODS:The authors analyzed outcomes among 1892 patients who received treatment for newly diagn...

journal_title：Cancer

authors： Estey E,deLima M,Strom S,Pierce S,Freireich EJ,Keating MJ

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:There is significant need for quality follow-up care to optimize long-term outcomes for the growing population of lower gastrointestinal (GI) cancer survivors. Patient-reported outcomes (PROs) provide valuable information regarding late and long-term effects (LLTEs). METHODS:A convenience sample from 1129 c...

journal_title：Cancer

authors： Frick MA,Vachani CC,Hampshire MK,Bach C,Arnold-Korzeniowski K,Metz JM,Hill-Kayser CE

更新日期：2017-05-15 00:00:00

abstract：:Acquired myeloperoxidase deficiency has been reported in several hematological malignancies. The clinical course of a patient with acute myelomonocytic leukemia is described which was characterized by staphylococcal infections prior to therapy and again during a period of relapse. Neutropenia was not a feature of thes...

journal_title：Cancer

authors： Kitahara M,Kushner JP

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:The current study was performed to create a scoring system to estimate the survival of patients with metastatic spinal cord compression (MSCC). METHODS:Based on a multivariate survival analysis of 1852 patients who were treated with radiotherapy (RT) for MSCC, a scoring system was developed. The system incl...

journal_title：Cancer

authors： Rades D,Dunst J,Schild SE

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Historically, patients with nonmetastatic renal cell carcinoma (RCC) involving adjacent organs have been considered inoperable and incurable. The oncologic efficacy of an aggressive surgical approach was evaluated in a selected subpopulation of RCC patients. Further, an attempt was made to define the clinica...

journal_title：Cancer

authors： Margulis V,Sánchez-Ortiz RF,Tamboli P,Cohen DD,Swanson DA,Wood CG

更新日期：2007-05-15 00:00:00

abstract：BACKGROUND:It has been shown that adoptive immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T-lymphocytes (CTL) is effective for the treatment of EBV-induced lymphoproliferative disease in stem cell transplantation recipients and organ transplantation recipients. The role of EBV CTL in other tumors for wh...

journal_title：Cancer

authors： Lucas KG,Salzman D,Garcia A,Sun Q

更新日期：2004-05-01 00:00:00

abstract：:Elevated serum lactic dehydrogenase (LDH) levels, 595 to 615 microns/ml (normal less than 225 microns/ml) with predominance of LDH isoenzymes 2 and 3 was the early and only sign of occult malignant lymphoma in three patients. In the first patient, overt lymphoma appeared clinically only 2 months after the finding of e...

journal_title：Cancer

authors： Rotenberg Z,Weinberger I,Fuchs Y,Erdberg A,Davidson E,Agmon J

更新日期：1984-10-01 00:00:00

abstract：:Pericardial effusion and trifascicular block developed 5 years following mediastinal irradiation for Hodgkin's disease in a 19-year-old patient. Another 24-year-old patients had an acute myocardial infarction followed by severe angina pectoris 5 years following mediastinal irradiation for the same disease. A pericardi...

journal_title：Cancer

authors： Ali MK,Kahlil KG,Fuller LM,Leachman RD,Sullivan MP,Loh KK,Gamble JF,Shullenberger CC

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:A national data source for identifying patients with cancer enrolled in Medicaid is needed to evaluate cancer care for low-income, publicly insured patients. In this study, a population-based data set of patients diagnosed with cancer and enrolled in Medicaid was created and evaluated. The objective was to c...

journal_title：Cancer

authors： Bradley CJ,Stevens JL,Enewold L,Warren JL

更新日期：2021-01-15 00:00:00

abstract：BACKGROUND:Telomeres are protective structures at the ends of linear chromosomes, regulated by a host of associated proteins. When telomeres become dysfunctional, genomic instability ensues. The vast majority of cells undergo apoptosis, although a rare cell may survive and become tumorigenic. METHODS:The authors used ...

journal_title：Cancer

authors： Prescott J,McGrath M,Lee IM,Buring JE,De Vivo I

更新日期：2010-09-15 00:00:00

abstract：BACKGROUND:To enhance the efficacy of chemotherapy for medullary thyroid carcinoma (MTC), we evaluated the effect of combining radioimmunotherapy (RAIT) with 90Y-anticarcinoembryonic antigen (CEA) monoclonal antibody MN-14 and chemotherapy in nude mice bearing human MTC xenografts. A preliminary study evaluated doxorub...

journal_title：Cancer

authors： Stein R,Chen S,Reed L,Richel H,Goldenberg DM

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The management of children with hypothalamic (H) and/or chiasmatic (C) tumors remains controversial. We evaluated the impact of clinical and neuroimaging parameters and primary therapy on overall (OS) and progression-free (PFS) survival and on neuroendocrine and neurocognitive outcome in children with H and/...

journal_title：Cancer

authors： Fouladi M,Wallace D,Langston JW,Mulhern R,Rose SR,Gajjar A,Sanford RA,Merchant TE,Jenkins JJ,Kun LE,Heideman RL

更新日期：2003-02-15 00:00:00

abstract：:Three cases of carcinoid tumor arising in the trachea are reported and contrasted with carcinoids arising in bronchi and carcinoids in general. Only eleven other documented examples of tracheal carcinoids are found in the English literature. The true prevalence of carcinoids primary in the trachea cannot be accurately...

journal_title：Cancer

authors： Briselli M,Mark GJ,Grillo HC

更新日期：1978-12-01 00:00:00