Turcot's syndrome. Evidence for autosomal dominant inheritance.

abstract：:Esophageal prothesis (EP) is a palliative treatment for inoperable neoplastic stenosis. Ninety-one patients were candidates for EP placement between 1978 and 1983. EP placement was successful in 77 patients. Of these: 85% had primary esophageal cancer; 15% had bronchial or mediastinal carcinoma; 83% had stenosis in th...

journal_title：Cancer

authors： Chavy AL,Rougier M,Pieddeloup C,Kac J,Laplanche AC,Elias DM,Ducreux MP,Zummer-Rubinstein K,Zimmermann PA,Charbit MA

更新日期：1986-04-01 00:00:00

abstract：:Although the conference could not provide a definitive etiologic explanation for the observed increase in incidence of human brain tumors, particularly among the elderly, nevertheless, this interdisciplinary gathering of prominent scientists and clinicians proved invaluable in identifying new avenues of research. Clea...

journal_title：Cancer

authors： Brem S,Rozental JM,Moskal JR

更新日期：1995-08-15 00:00:00

abstract：BACKGROUND:Telomerase is commonly recognized as an effective anticancer target. The human telomerase reverse transcriptase (hTERT), the rate-limiting component of telomerase, is expressed in most malignant tumors, but it is not found in most normal somatic cells. Here, we report a real-time and noninvasive method to mo...

journal_title：Cancer

authors： Yu ST,Li C,Lü MH,Liang GP,Li N,Tang XD,Wu YY,Shi CM,Chen L,Li CZ,Cao YL,Fang DC,Yang SM

更新日期：2012-04-01 00:00:00

abstract：:Twenty-four patients who developed extramedullary disease during the course of Philadelphia chromosome-positive chronic myelogenous leukemia are described. The most frequent sites of extramedullary disease were lymph nodes (54%), bone (37%), and skin and soft tissue (29%). The appearance of extramedullary disease was ...

journal_title：Cancer

authors： Terjanian T,Kantarjian H,Keating M,Talpaz M,McCredie K,Freireich EJ

更新日期：1987-01-15 00:00:00

abstract：BACKGROUND:There is limited understanding of the association between barriers to care and clinical outcomes within patient navigation programs. METHODS:Secondary analyses of data from the intervention arms of the Patient Navigation Research Program were performed, which included navigated participants with abnormal br...

journal_title：Cancer

authors： Ramachandran A,Snyder FR,Katz ML,Darnell JS,Dudley DJ,Patierno SR,Sanders MR,Valverde PA,Simon MA,Warren-Mears V,Battaglia TA,Patient Navigation Research Program Investigators.

更新日期：2015-11-15 00:00:00

abstract：BACKGROUND:The authors undertook a prospective evaluation of the clinical value of 2-fluoro [18-]-2-deoxyglucose positron emission tomography (FDG-PET) in the detection and staging of malignant lymphoma compared with computed tomography (CT) and bone marrow biopsy (BMB). METHODS:Fifty-two consecutive patients with unt...

journal_title：Cancer

authors： Buchmann I,Reinhardt M,Elsner K,Bunjes D,Altehoefer C,Finke J,Moser E,Glatting G,Kotzerke J,Guhlmann CA,Schirrmeister H,Reske SN

更新日期：2001-03-01 00:00:00

abstract：:Thirty-six patients with polycythemia vera were treated with hydroxyurea for 12 to 67 months. Nineteen patients were previously treated with other drugs. In the vast majority of patients, an average dose of 1 g/day was sufficient to control hematocrit value and platelet count. Half of the patients experienced relief o...

journal_title：Cancer

authors： Sharon R,Tatarsky I,Ben-Arieh Y

更新日期：1986-02-15 00:00:00

abstract：BACKGROUND:The current study was conducted to examine gender differences in the effect of grief reactions and burnout on emotional distress among clinical oncologists. METHODS:The participants included a convenience sample of 178 oncologists from Israel (52 of whom were women) and Canada (48 of whom were women). Oncol...

journal_title：Cancer

authors： Granek L,Krzyzanowska MK,Nakash O,Cohen M,Ariad S,Barbera L,Levy R,Ben-David M

更新日期：2016-12-01 00:00:00

abstract：:A previously unreported association of Brenner and adenomatoid tumor found in the tunica vaginalis testis is presented. Many ultrastructural features found in mesothelial cells such as intercellular spaces, deeply indented nuclei, tonofilaments and tight desmosomes, were also shared by cells present in both neoplastic...

journal_title：Cancer

authors： Nogales FF Jr,Matilla A,Ortega I,Alvarez T

更新日期：1979-02-01 00:00:00

abstract：:Nickel-related cancers of the respiratory tract have been recognized for nearly 50 years and represent a unique opportunity for prevention among refinery workers. Studies of exposed employees have been conducted in which evaluations were made of the histopathologic changes in the respiratory mucosa and the body burden...

journal_title：Cancer

authors： Barton RT,Hogetveit AC

更新日期：1980-06-15 00:00:00

abstract：BACKGROUND:Many histologic classifications of thymic epithelial tumors have been reported to date, but to the authors' knowledge, none of them closely reflect the clinical behavior or prognosis of the tumor. Therefore, it is necessary to establish a biologic marker for thymic epithelial tumors. Variants of CD44 may be ...

journal_title：Cancer

authors： Sonobe S,Miyamoto H,Nobukawa B,Izumi H,Futagawa T,Ishikawa N,Yamazaki A,Uekusa T,Abe H,Suda K

更新日期：2005-05-15 00:00:00

abstract：BACKGROUND:Metastatic adenocarcinoma in the liver with an unidentified primary tumor site is a common clinical problem. Pathologists often are asked to identify the primary tumor site. The histologic picture itself usually is not helpful, because the histology may be similar in the metastases of tumors with different p...

journal_title：Cancer

authors： Tot T

更新日期：1999-01-01 00:00:00

abstract：:Thyroid function and scans were evaluated in fifty disease-free patients 2 to 16 years after receiving neck irradiation for the treatment of Hodgkin's disease. Twenty-five of 50 patients had abnormal thyroid studies: eight were hypothyroid, two were hypothyroid and had abnormal scans, and fifteen had abnormal scans. O...

journal_title：Cancer

authors： Nelson DF,Reddy KV,O'Mara RE,Rubin P

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:All edemas result from an imbalance between capillary filtration and tissue (lymph) drainage. This basic approach was adopted to investigate mechanisms for chronic arm edema following breast carcinoma treatment. METHODS:A review of causes of lymphedema is presented plus the traditional pathophysiology of br...

journal_title：Cancer

authors： Mortimer PS

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:Primary and metastatic malignancies that originate in the sinonasal tract are rare and histologically diverse. The role of fine-needle aspiration biopsy (FNAB) and the cytomorphologic features of these tumors have not been specifically addressed. METHODS:The authors reviewed 22 cytology cases (20 FNABs, 1 s...

journal_title：Cancer

authors： Helsel JC,Bardales RH,Mukunyadzi P

更新日期：2003-04-25 00:00:00

abstract：:Malignant thymoma is a relatively rare condition and a review of the literature reveals approximately 100 reported cases. Only a small percentage of these have been treated with megavoltage radiation therapy; therefore, it is difficult to find the necessary information to establish a proper time-dose relationship for ...

journal_title：Cancer

authors： Marks RD Jr,Wallace KM,Pettit HS

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:The American Joint Committee on Cancer (AJCC) 7th edition introduced major changes in the staging of lung cancer, including the tumor (T), node (N), metastasis (M)-TNM-system and new stage/prognostic site-specific factors (SSFs), collected under the Collaborative Stage Version 2 (CSv2) Data Collection System...

journal_title：Cancer

authors： Chen VW,Ruiz BA,Hsieh MC,Wu XC,Ries LA,Lewis DR

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNA) has been successful in diagnosing epithelial lesions of the breast. Its role in the evaluation of spindle cell and mesenchymal lesions of the breast, which include a variety of benign and malignant conditions, is less clear. This article discusses the cytologic features an...

journal_title：Cancer

authors： Chhieng DC,Cangiarella JF,Waisman J,Fernandez G,Cohen JM

更新日期：1999-12-25 00:00:00

abstract：BACKGROUND:Despite recent improvements in the treatment of acute lymphoblastic leukemia (ALL), adult patients still have an overall poor outcome. The future of ALL management relies on the introduction of novel targeted therapies. The authors sought to assess if protein kinases (PKs), frequently deregulated in cancer, ...

journal_title：Cancer

authors： Messina M,Chiaretti S,Tavolaro S,Peragine N,Vitale A,Elia L,Sica S,Levis A,Guarini A,Foà R

更新日期：2010-07-15 00:00:00

abstract：BACKGROUND:The prognosis of patients with clinically staged hilar nodal involvement (Stage N1) or clinical Stage II non-small cell lung cancer (NSCLC, Stage T1-2N1M0) treated with radiation therapy (RT) alone is not well established. METHODS:Records of 758 patients with clinical Stage I-III NSCLC treated with RT were ...

journal_title：Cancer

authors： Rosenthal SA,Curran WJ Jr,Herbert SH,Hughes EN,Sandler HM,Stafford PM,McKenna WG

更新日期：1992-11-15 00:00:00

abstract：:A total of 289 cases with malignant pleuroperitoneal effusions were reviewed, and their prognosis were analyzed in relation to the following factors: (1) chronologically divided series; (2) previous tumorectomy of the primary lesion; (3) presence or absence of other metastases; (4) site of effusion; (5) site of the pr...

journal_title：Cancer

authors： Yamada S,Takeda T,Matsumoto K

更新日期：1983-01-01 00:00:00

abstract：:A prospective study was performed on 84 patients with neuroendocrine pancreatic tumors. Fifty-nine (70%) had malignant tumors and received causal medical treatment. Streptozotocin in combination with 5-fluorouracil or doxorubicin was used as first-line treatment and produced overall objective responses in 20 of 44 (45...

journal_title：Cancer

authors： Eriksson B,Skogseid B,Lundqvist G,Wide L,Wilander E,Oberg K

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Telomerase is a ribonucleoprotein that maintains telomeric base pair repeats at the ends of mammalian chromosomes during DNA replication. Telomerase is expressed in various human tumors, some normal tissues, and immortalized cell lines. The assay of telomerase activity has potential as an adjunct for cancer ...

journal_title：Cancer

authors： Mu XC,Brien TP,Ross JS,Lowry CV,McKenna BJ

更新日期：1999-04-25 00:00:00

abstract：:Gynecologic cancers present unusual opportunities to explore the fruits of well-designed clinical trials to assess the value of existing treatment using a combined modality approach soon after diagnosis. Cancers of the ovary and uterus have well-defined, familiar natural histories. Pathways of spread are clear and rea...

journal_title：Cancer

authors： DeVita VT Jr,Wasserman TH,Young RC,Carter SK

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Patients with prostate cancer receiving androgen deprivation therapy (ADT) are at risk of sleep disturbance; however, to the authors' knowledge, the mechanisms by which ADT may affect sleep are not well understood. The current study compared objective and subjective sleep disturbance in ADT recipients and co...

journal_title：Cancer

authors： Gonzalez BD,Small BJ,Cases MG,Williams NL,Fishman MN,Jacobsen PB,Jim HSL

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Low frequency epithelial cells in bone marrow from colorectal carcinoma patients are associated with an increased risk of recurrence and decreased survival. Current immunohistochemical approaches to detect epithelial cells in bone marrow aspirates rely on antibodies against cytokeratin 18 (CK18). The predict...

journal_title：Cancer

authors： Litle VR,Warren RS,Moore D 2nd,Pallavicini MG

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:China's lung cancer (LC) burden plays a pivotal role in the global cancer epidemic. Comparing LC burden and population attributable fractions (PAFs) of risk factors between China and other countries/regions is essential to inform effective intervention. The Global Burden of Disease (GBD) study provides a uni...

journal_title：Cancer

authors： Wang N,Mengersen K,Tong S,Kimlin M,Zhou M,Hu W

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:The first analysis of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial (median follow-up, 33 months) demonstrated that in adjuvant endocrine therapy for postmenopausal patients with early-stage breast cancer, anastrozole was superior to tamoxifen in terms of disease-free survival (DFS), time to r...

journal_title：Cancer

authors： Baum M,Buzdar A,Cuzick J,Forbes J,Houghton J,Howell A,Sahmoud T,ATAC (Arimidex, Tamoxifen Alone or in Combination) Trialists' Group.

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Cancer cell expression of costimulatory molecule B7-H1 has been implicated as a potent inhibitor of T-cell-mediated antitumoral immunity. The authors recently reported that B7-H1 is aberrantly expressed in primary renal cell carcinoma (RCC). Blockade of B7-H1, as demonstrated in several murine cancer models,...

journal_title：Cancer

authors： Thompson RH,Gillett MD,Cheville JC,Lohse CM,Dong H,Webster WS,Chen L,Zincke H,Blute ML,Leibovich BC,Kwon ED

更新日期：2005-11-15 00:00:00

abstract：BACKGROUND:p16 is strongly overexpressed in dysplastic cervical cells because of the transforming activity of the E7 oncogene of all high-risk human papillomavirus (HR-HPV) types and may be easily revealed by immunochemistry: p16 may, therefore, be considered a surrogate marker for the activated oncogene expression of ...

journal_title：Cancer

authors： Carozzi F,Cecchini S,Confortini M,Becattini V,Cariaggi MP,Pontenani G,Sani C,Ciatto S

更新日期：2006-04-25 00:00:00