Medical treatment and long-term survival in a prospective study of 84 patients with endocrine pancreatic tumors.

abstract：:In order to validate xenografted small cell lung carcinomas (SCLC) for biological studies, the authors established 12 lung neuroendocrine (NE) tumors (eight typical SCLC and four atypical NE tumors [ANE]) by heterotransplantation onto nude mice. Their characterization was performed using serial ultrastructural, enzyma...

journal_title：Cancer

authors： Brambilla E,Jacrot M,Batandier C,Brichon PY,Morel F,Nagy-Mignotte H,Paramelle B,Brambilla C

更新日期：1989-09-15 00:00:00

abstract：:A fatal massive hepatic necrosis with widespread thrombotic occlusion of the small hepatic veins developed in two of 68 patients treated with DTIC for advanced melanoma in a randomized study. Thirteen similar reactions, in patients treated with single-agent DTIC, are reported in the literature. Several clinical and pa...

journal_title：Cancer

authors： Ceci G,Bella M,Melissari M,Gabrielli M,Bocchi P,Cocconi G

更新日期：1988-05-15 00:00:00

abstract：BACKGROUND:There is controversy regarding the optimal management of thyroid cancer. The proportion of patients with low-risk thyroid cancer who received radioactive iodine (RAI) treatment increased over the last 20 years, and little is known about the role played by clinicians in hospital-level RAI use for low-risk dis...

journal_title：Cancer

authors： Haymart MR,Banerjee M,Yang D,Stewart AK,Koenig RJ,Griggs JJ

更新日期：2013-01-15 00:00:00

abstract：:Seventy-seven patients with relapsed or refractory acute leukemia and three with acute blastic chronic myeloid leukemia (CML) were treated in an open Phase II study using mitoxantrone 12 mg/m2 intravenously daily X 5 days. Complete remission (CR) was achieved in 32 of 80 (40%), including 23/45 (52%) with relapsed acut...

journal_title：Cancer

authors： Bezwoda WR,Bernasconi C,Hutchinson RM,Winfield DA,de Bock R,Mandelli F

更新日期：1990-08-01 00:00:00

abstract：:The unusual genetic disorder epidermolysis bullosa dystrophica has been reported in several patients in whom the chronic cutaneous scars led to the development of cutaneous squamous cell carcinoma. However, only one of these previously reported cases involved the autosomal dominant form of the disease; the remainder o...

journal_title：Cancer

authors： Schwartz RA,Birnkrant AP,Rubenstein DJ,Kim U,Burgess GH,Stoll HL Jr,Chai SW,Southwick GJ,Milgrom H

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:For most cancers, information on treatment tolerance and results for elderly patients is quite limited. This study was conducted to investigate the feasibility and results of curative nonsurgical treatment of patients age 75 years or older with anal carcinoma. METHODS:From January 1976 through June 1996, in...

journal_title：Cancer

authors： Allal AS,Obradovic M,Laurencet F,Roth AD,Spada A,Marti MC,Kurtz JM

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The authors purpose in this study was to clarify the difference in terms of clinicopathologic features between gastric cancer (GC) with high numbers of DNA methylated genes and CpG island methylator phenotype (CIMP)-positive GC as originally defined. METHODS:We analyzed DNA methylation of 12 tumor-related g...

journal_title：Cancer

authors： Oue N,Mitani Y,Motoshita J,Matsumura S,Yoshida K,Kuniyasu H,Nakayama H,Yasui W

更新日期：2006-03-15 00:00:00

abstract：:The purpose of this study is to evaluate benign and/or malignant thyroid tumors with 201TI thyroid scan. We studied 76 cases of histologically verified thyroid tumors, all seen as cold nodules on the 123I thyroid scan. 201TI thyroid scan was performed 5-15 minutes (early scan) and 3-5 hours (delayed scan) after intrav...

journal_title：Cancer

authors： Ochi H,Sawa H,Fukuda T,Inoue Y,Nakajima H,Masuda Y,Okamura T,Onoyama Y,Sugano S,Ohkita H,Tei Y,Kamino K,Kobayashi Y

更新日期：1982-07-15 00:00:00

abstract：BACKGROUND:Cancer clinicians do not receive routine training in the psychosocial aspects of patient care such as how to communicate bad news or respond to patients who have unrealistic expectations of cure. Postgraduate workshops may be an effective way to increase interpersonal skills in managing these stressful patie...

journal_title：Cancer

authors： Baile WF,Kudelka AP,Beale EA,Glober GA,Myers EG,Greisinger AJ,Bast RC Jr,Goldstein MG,Novack D,Lenzi R

更新日期：1999-09-01 00:00:00

abstract：:The urinary neopterin excretion was measured by high-performance liquid chromatography in 417 healthy subjects and in 76 patients with clinically and pathohistologically verified neoplasias of the urinary tract (bladder tumor, carcinoma of the prostate, and renal cell carcinoma). The patients with early tumor stages b...

journal_title：Cancer

authors： Aulitzky W,Frick J,Fuchs D,Hausen A,Reibnegger G,Wachter H

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective study was to determine those prognostic factors associated with response to a second-line chemotherapy in patients with metastatic breast carcinoma (MBC) that was previously responsive to a first-line chemotherapy. METHODS:The 70 MBC patients studied had previously responded to...

journal_title：Cancer

authors： Brun B,Benchalal M,Lebas C,Piedbois P,Lin M,Lebourgeois JP

更新日期：1997-06-01 00:00:00

abstract：:The prognostic significance of ploidy level was studied in prostatic carcinoma and compared with the prognostic significance of morphologic grade and clinical stage. A nonselected group of 145 patients was studied in whom prostatic carcinoma was diagnosed by fine-needle aspiration biopsy at the Karolinska Hospital in ...

journal_title：Cancer

authors： Forsslund G,Esposti PL,Nilsson B,Zetterberg A

更新日期：1992-03-15 00:00:00

abstract：BACKGROUND:Although the anticancer effects of progesterone therapy for patients with endometrial carcinoma are widely acknowledged, a detailed assessment of the resultant morphologic alterations in tumor tissue kinetics has hitherto been lacking. METHODS:Biopsy and hysterectomy specimens of 14 endometrial carcinomas (...

journal_title：Cancer

authors： Saegusa M,Okayasu I

更新日期：1998-07-01 00:00:00

abstract：:Previous studies and those of the authors have reported about raised levels of lipid-bound sialic acid (LSA) in sera of patients with various neoplasms. Most authors have used the method of Katopodis and Stock for isolating serum LSA. Because of the discrepancy of the amount of extracted LSA with the content of pure g...

journal_title：Cancer

authors： Voigtmann R,Pokorny J,Meinshausen A

更新日期：1989-12-01 00:00:00

abstract：:Major advances have been made in melanoma treatment with the use of molecularly targeted therapies and immunotherapies, and numerous regimens are now approved by the US Food and Drug Administration for patients with stage IV disease. However, therapeutic resistance remains an issue to both classes of agents, and relia...

journal_title：Cancer

authors： Szczepaniak Sloane RA,Gopalakrishnan V,Reddy SM,Zhang X,Reuben A,Wargo JA

更新日期：2017-06-01 00:00:00

abstract：:In this study of 454 colorectal carcinoma colectomy specimens, (289 were associated with and 165 were unassociated with schistosomiasis. Schistosome infestation was found to play an etiologic role in bowel malignancy in patients having diffuse involvement of the large intestine and a history of ten years or more of co...

journal_title：Cancer

authors： Ming-Chai C,Chi-Yuan C,Pei-Yu C,Jen-Chun H

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Hyalinizing clear cell carcinoma (HCCC) is an uncommon malignant salivary gland tumor that was characterized only recently as a distinct entity. Because of its histologic similarity to several other primary and metastatic tumors and its purported favorable clinical outcome after local resection, it is import...

journal_title：Cancer

authors： Solar AA,Schmidt BL,Jordan RC

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Deletion or loss of heterozygosity (LOH) at the polymorphic loci on the short arm of chromosome 3 has been reported in a large number of renal cell, small cell lung, non-small cell lung, and cervical carcinomas, suggesting the presence of one or more putative tumor suppressor genes at chromosome 3p. Similar ...

journal_title：Cancer

authors： el-Naggar AK,Lee MS,Wang G,Luna MA,Goepfert H,Batsakis JG

更新日期：1993-08-01 00:00:00

abstract：:Carcinoembryonic antigen is only a tumor assoicated antigen and is less clinically useful than the original report suggested. However, the CEA assays in clinical use utilize reagents operationally defined by old criteria. There is now abundant evidence that "CEA" consists of a heterogenous family of related glycoprote...

journal_title：Cancer

authors： Alpert E

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:The efficacy of energy conservation and activity management (ECAM) for fatigue reduction and maintenance of functional performance has never been evaluated in adults with cancer who are undergoing treatment. METHODS:A randomized clinical trial compared an ECAM intervention with a control intervention focuse...

journal_title：Cancer

authors： Barsevick AM,Dudley W,Beck S,Sweeney C,Whitmer K,Nail L

更新日期：2004-03-15 00:00:00

abstract：BACKGROUND:Receipt of chemotherapy at the end of life (EOL) is considered an indicator of poor quality of care for medical oncology. The objective of this study was to characterize the use of radiotherapy (RT) in patients with nonsmall cell lung cancer (NSCLC) during the same period. METHODS:Treatment characteristics ...

journal_title：Cancer

authors： Kapadia NS,Mamet R,Zornosa C,Niland JC,D'Amico TA,Hayman JA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:It is unclear whether patients with Stage II colon carcinoma should be offered adjuvant chemotherapy. Therefore, the authors analyzed the risk factors of these patients to identify high-risk subgroups who may benefit from such treatment. METHODS:The data from 305 patients with Stage II colon carcinoma docum...

journal_title：Cancer

authors： Merkel S,Wein A,Günther K,Papadopoulos T,Hohenberger W,Hermanek P

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:Lung carcinoma represents the most frequent cause of cancer death worldwide because of tumor metastases. The objective of the current study was to analyze the immunologic response during the progress of lung carcinoma metastasis. METHODS:The authors established two tumor cell lines that were derived from pr...

journal_title：Cancer

authors： So T,Takenoyama M,Ichiki Y,Mizukami M,So T,Hanagiri T,Sugio K,Yasumoto K

更新日期：2005-01-01 00:00:00

abstract：:Mesenchymal chondrosarcoma of bone and soft tissues treated at the Istituto Ortopedico Rizzoli are reviewed. The skeletal locations were prominent in five cases. Only two cases were in the soft tissues. Radiographic picture in the bone shows an aggressive osteolysis, with soft tissues invasion. Histologic picture is t...

journal_title：Cancer

authors： Bertoni F,Picci P,Bacchini P,Capanna R,Innao V,Bacci G,Campanacci M

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Chronic myeloid leukemia (CML) can be treated effectively with tyrosine kinase inhibitor therapy directed at BCR-ABL, but access to care, medication cost, and adherence may be barriers to treatment. This study was designed to determine whether the insurance status at diagnosis influences CML patient outcomes...

journal_title：Cancer

authors： Perry AM,Brunner AM,Zou T,McGregor KL,Amrein PC,Hobbs GS,Ballen KK,Neuberg DS,Fathi AT

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The epidophyllotoxin VM 26 has been shown to have single-agent activity in patients with diffuse aggressive lymphoma. In an attempt to determine its activity in combination with other agents known to be effective in lymphoma, a Phase II trial of a novel chemotherapy regimen was conducted. METHODS:Forty-two ...

journal_title：Cancer

authors： Gordon LI,Andersen J,Gregory S,Mazza J,Chervenick P,Hahn RG,O'Connell MJ

更新日期：1993-01-15 00:00:00

abstract：BACKGROUND:With the move away from classical radical mastectomy to ever more skin-sparing procedures, there has been an ongoing discussion about how much skin and subcutaneous tissue should be resected to perform an adequate mastectomy while leaving viable skin flaps. One of the common recommendations is to dissect jus...

journal_title：Cancer

authors： Beer GM,Varga Z,Budi S,Seifert B,Meyer VE

更新日期：2002-03-15 00:00:00

abstract：:Late side effects of chemotherapy were studied in 51 women who had received at least 300 mg of melphalan for ovarian cancer and had survived for at least three years. Hematologic, statistical, and cytogenetic methods were employed. Six cases of iatrogenic leukemia were found. They appeared to represent a hematologic e...

journal_title：Cancer

authors： Einhorn N,Eklund G,Franzén S,Lambert B,Lindsten J,Söderhäll S

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Previously published studies concerning autopsy findings in ovarian cancer failed to consider the broad differences in factors that influence the course of disease. Furthermore, those studies were conducted when the currently accepted standards in diagnostics and therapy had not been fully established. The o...

journal_title：Cancer

authors： Güth U,Huang DJ,Bauer G,Stieger M,Wight E,Singer G

更新日期：2007-09-15 00:00:00

abstract：BACKGROUND:The balance among cell proliferation, cell differentiation, and cell death determines the cell number in a population as well as the size or even the stage of a tumor. Thus, to improve our understanding of the pathogenesis of neoplasms, it is important to investigate the regulation of both cell proliferation...

journal_title：Cancer

authors： Shen KL,Harn HJ,Ho LI,Yu CP,Chiu SC,Lee WH

更新日期：1998-06-15 00:00:00