Hyalinizing clear cell carcinoma: case series and comprehensive review of the literature.

Abstract:

BACKGROUND:Hyalinizing clear cell carcinoma (HCCC) is an uncommon malignant salivary gland tumor that was characterized only recently as a distinct entity. Because of its histologic similarity to several other primary and metastatic tumors and its purported favorable clinical outcome after local resection, it is important to recognize the features of this unusual tumor. METHODS:The authors present 8 new, fully characterized cases of HCCC and systematically reviewed 44 other cases of HCCC reported in the English language literature from 1980 to 2008. Historic cases were reviewed, and available data regarding morphology, special stains, demographics, clinical presentation, radiographic findings, management, and outcomes were extracted. Data from the current series were compared with the earlier published literature. RESULTS:To the best of the authors' knowledge, this was the largest reviewed series of HCCC and included a total of 52 cases. The findings, which included key histologic features, clinical presentation, and outcome, generally were consistent with what was reported previously. However, the current review revealed that 25% of patients reported in the literature had metastatases at initial presentation, including 10 of 44 patients who had metastases to regional lymph nodes and 1 patient who had metastasis to the lung. The authors were unable to identify any specific histologic features that would predict this behavior. CONCLUSIONS:The current results indicated that HCCC is less indolent than was believed previously; therefore, regional lymph node dissection should be considered in conjunction with wide local excision for patients with HCC.

journal_name

Cancer

journal_title

Cancer

authors

Solar AA,Schmidt BL,Jordan RC

doi

10.1002/cncr.23974

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

75-83

issue

1

eissn

0008-543X

issn

1097-0142

journal_volume

115

pub_type

杂志文章,评审

相关文献

CANCER文献大全
  • The multidiscipline team in a cancer center.

    abstract::To surgery, radiation, and chemotherapy for cancer has been added a fourth modality: multidisciplinary therapy, which is improving the survival and cure rate among children. Specialists working together in a coordinated effort suspect, confirm, then treat cancer; follow and rehabilitate the patient; analyze and report...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197503)35:3+<876::aid-cncr282035

    authors: Murphy ML

    更新日期:1975-03-01 00:00:00

  • Alpha-fetoprotein and human chorionic gonadotropin in a patient with a primary intracranial germ cell tumor.

    abstract::A 17 year old man with a primary intracranial germ cell tumor in the pituitary region is reported. Both serum alpha-fetoprotein (AFP) and serum human chorionic gonadotropin (hCG) were found elevated preoperatively. Normal levels of serum AFP and hCG were found after operation and radiotherapy. By indirect immunofluore...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197806)41:6<2315::aid-cncr282041

    authors: Nørgaard-Pedersen B,Lindholm J,Albrechtsen R,Arends J,Diemer NH,Riishede J

    更新日期:1978-06-01 00:00:00

  • Quantification of telomerase activity in sporadic colorectal carcinoma: association with tumor growth and venous invasion.

    abstract:BACKGROUND:Activation of telomerase, a ribonucleoprotein enzyme complex that synthesizes telomere repeats, is associated with acquisition of unlimited cellular proliferation and is commonly detected in human cancer. Measurement of telomerase activity (TA) may provide important information as a diagnostic marker or a pr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(20000315)88:6<1304::aid-cn

    authors: Shoji Y,Yoshinaga K,Inoue A,Iwasaki A,Sugihara K

    更新日期:2000-03-15 00:00:00

  • Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation.

    abstract:BACKGROUND:A previous study found that medroxyprogesterone acetate (MPA) delayed the in vivo growth of three (AsPC-1, Capan-2, and MiaPaCa-2) of nine human pancreatic carcinoma cell lines transplanted into nude mice (Cancer 1995; 75:1263-72). The current study was undertaken to evaluate the basis for this inhibitor. M...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Abe M,Yamashita J,Ogawa M

    更新日期:2000-05-01 00:00:00

  • Effectiveness of once weekly total skin electron beam therapy in mycosis fungoides and Sezary syndrome.

    abstract::During the past eight years, 137 patients with mycosis fungoides were given total skin electron beam therapy (TSEB) using 2.5 to 4 MeV electrons. A single treatment delivers 400 rads to the entire skin surface, and patients are treated once a week for six to eight consecutive weeks. All have been followed for a median...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810301)47:5<870::aid-cncr28204

    authors: Nisce LZ,Safai B,Kim JH

    更新日期:1981-03-01 00:00:00

  • Cancer care challenges in developing countries.

    abstract:BACKGROUND:Health systems in Sub-Saharan Africa are not prepared for the rapid rise in cancer rates projected in the region over the next decades. More must be understood about the current state of cancer care in this region to target improvement efforts. Yaounde General Hospital (YGH) currently is the only site in Cam...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26681

    authors: Price AJ,Ndom P,Atenguena E,Mambou Nouemssi JP,Ryder RW

    更新日期:2012-07-15 00:00:00

  • Tobacco-induced changes in oral leukoplakic epithelium.

    abstract::A study of 112 biopsy specimens from Danish oral leukoplakia patients and 145 biopsy specimens from Indian leukoplakia patients revealed a chevron-like keratinization of the epithelium in a number of cases. Clinically, this type of keratinization was often characterized by a pumice-like appearance. The clinical and hi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800501)45:9<2330::aid-cncr2820

    authors: Pindborg JJ,Reibel J,Roed-Peterson B,Mehta FS

    更新日期:1980-05-01 00:00:00

  • Phosphorylated CXCR4 is associated with poor survival in adults with B-acute lymphoblastic leukemia.

    abstract:BACKGROUND:CXC chemokine receptor 4 (CXCR4) is activated by phosphorylation (pCXCR4) and is essential for the migration of hematopoietic precursors to bone marrow. CXCR4 overexpression predicts a poor prognosis in patients with acute myeloid leukemia. Data regarding the prognostic impact of CXCR4 in patients with B-acu...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26113

    authors: Konoplev S,Jorgensen JL,Thomas DA,Lin E,Burger J,Kantarjian HM,Andreeff M,Medeiros LJ,Konopleva M

    更新日期:2011-10-15 00:00:00

  • A new method for analyzing the cell kinetics of human brain tumors by double labeling with bromodeoxyuridine in situ and with iododeoxyuridine in vitro.

    abstract:BACKGROUND:Cell kinetics studies performed with immunohistochemical techniques to estimate the S-phase fraction have elucidated the proliferative potential of individual brain tumors. METHODS:The authors developed a new double-labeling method that enables other cell kinetics variables, including the duration of the S-...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930515)71:10<3109::aid-cncr282

    authors: Shibuya M,Ito S,Davis RL,Wilson CB,Hoshino T

    更新日期:1993-05-15 00:00:00

  • Spinal cord sparing reirradiation with helical tomotherapy.

    abstract:BACKGROUND:The purpose of this study was to present planning, feasibility, toxicity, and outcome of helical tomotherapy for spinal cord-sparing reirradiation of spinal metastases and tumors. METHODS:Thirty-six patients with spinal metastases and tumors who had undergone previous radiotherapy were reirradiated with hel...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25187

    authors: Sterzing F,Hauswald H,Uhl M,Herm H,Wiener A,Herfarth K,Debus J,Krempien R

    更新日期:2010-08-15 00:00:00

  • Stage III nodular lymphoreticular tumors (non-Hodgkin's lymphoma): results of central lymphatic irradiation.

    abstract::Since 1969, 29 previously untreated patients with Stage III nodular malignant lymphoreticular (MLT) have received total central lymphatic (TCL) irradiation. The volume irradiated included the entire abdomen, Waldeyer's ring, and preauricular nodes in addition to the usual regions encompassed by total nodal irradiation...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810501)47:9<2247::aid-cncr2820

    authors: Cox JD,Komaki R,Kun LE,Wilson JF,Greenberg M

    更新日期:1981-05-01 00:00:00

  • An era of therapeutic translation.

    abstract::Diagnostic advances currently have exceeded therapeutic gain. The present, however, is a transition phase. Chemotherapy, for example, has become curative for some tumors in recent years, rather than merely palliative, due to the precision permitted by advances in molecular biology. At this time, acceleration in the ba...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19901015)60:8+<1931::aid-cncr282

    authors: Gusberg SB

    更新日期:1987-10-15 00:00:00

  • Thyroid-associated antigens in routinely embedded carcinomas. Possibilities and limitations studied in 116 cases.

    abstract::Routinely embedded tumors (116 cases) were screened immunohistochemically for the thyroid-associated antigens, thyroglobulin and calcitonin, and for carcinoembryonic antigen (CEA). Also the influence of different fixatives, decalcification, and embedding procedures were studied. All follicular and papillary carcinomas...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840715)54:2<274::aid-cncr28205

    authors: Logmans SC,Jöbsis AC

    更新日期:1984-07-15 00:00:00

  • The prevalence of patients with colorectal carcinoma under care in the U.S.

    abstract:BACKGROUND:Prevalence usually is defined as the proportion of individuals alive who previously had a diagnosis of the disease, regardless of whether the individuals still are receiving treatment or are cured. The objective of this study was to estimate the proportion of elderly patients with colorectal carcinoma (CRC) ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11631

    authors: Mariotto A,Warren JL,Knopf KB,Feuer EJ

    更新日期:2003-09-15 00:00:00

  • End-of-life care in Medicare beneficiaries dying with pancreatic cancer.

    abstract:BACKGROUND:The authors' goal was to characterize hospice enrollment and aggressiveness of care for pancreatic cancer patients at the end of life. METHODS:Surveillance, Epidemiology, and End Results and linked Medicare claims data (1992-2006) were used to identify patients with pancreatic cancer who had died (n = 22,81...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26115

    authors: Sheffield KM,Boyd CA,Benarroch-Gampel J,Kuo YF,Cooksley CD,Riall TS

    更新日期:2011-11-01 00:00:00

  • A safe and effective method for converting patients from transdermal to intravenous fentanyl for the treatment of acute cancer-related pain.

    abstract:BACKGROUND:The delayed effects (12-16 hours) of transdermal fentanyl make dose titration difficult during acute exacerbations of cancer pain. Patients at the authors' institution routinely are switched from transdermal to intravenous (IV) fentanyl using a 1:1 (transdermal:IV) conversion during severe episodes of pain. ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11457

    authors: Kornick CA,Santiago-Palma J,Schulman G,O'Brien PC,Weigand S,Payne R,Manfredi PL

    更新日期:2003-06-15 00:00:00

  • The role of lymph node dissection in the treatment of gallbladder carcinoma.

    abstract:BACKGROUND:Lymph node involvement is an important prognostic factor in gallbladder carcinoma (GBC). The lymph node involvement pattern, extent, and indications for systematic lymph node dissection for patients with advanced GBC were investigated. METHODS:Forty-one patients with GBC who underwent radical resection with...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19970301)79:5<892::aid-cnc

    authors: Shimada H,Endo I,Togo S,Nakano A,Izumi T,Nakagawara G

    更新日期:1997-03-01 00:00:00

  • Socioeconomic status and the risk of cervical intraepithelial neoplasia grade 3 among oncogenic human papillomavirus DNA-positive women with equivocal or mildly abnormal cytology.

    abstract:BACKGROUND:Low socioeconomic status (SES) is a reported risk factor for cervical carcinoma, but few studies have taken into account adequately the possibly confounding effects of oncogenic human papillomavirus (HPV) infection as well as access to screening and subsequent treatment. METHODS:Women (n = 5060 women) with ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21129

    authors: Khan MJ,Partridge EE,Wang SS,Schiffman M

    更新日期:2005-07-01 00:00:00

  • Combination hyperthermia and radiation therapy for malignant melanoma.

    abstract::Since 1975, clinical studies have been carried out to determine whether radiation when combined with localized hyperthermia evokes improved tumor control compared to that achieved with radiation alone. Local tumor hyperthermia was achieved using radiofrequency inductive heating at 27.12 MHz. In bulky lesions (greater ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820801)50:3<478::aid-cncr28205

    authors: Kim JH,Hahn EW,Ahmed SA

    更新日期:1982-08-01 00:00:00

  • The DNA content of human plasma cells.

    abstract::The DNA content of human plasma cells from myeloma patients relative to that of leukocytes was determined by flow and microscopic cytofluorometry after propidium iodide and fluorescent Feulgen staining, respectively. Mononucleated myeloma plasma cells from all of the 17 patients studied contained more DNA (17 to 58%) ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810515)47:10<2433::aid-cncr282

    authors: Brox L,Mowles D,Pollock B,Belch A

    更新日期:1981-05-15 00:00:00

  • Treatment of acute leukemia in adults.

    abstract::Improvement in the management of acute leukemia in adults has not progressed nearly so rapidly as has the treatment of childhood leukemia. One important difference is that most adults have myeloblastic or related forms of the disease (AML), whereas the majority of children have lymphoblastic leukemia (ALL). However, e...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197508)36:2+<775::aid-cncr282036

    authors: Clarkson BD,Dowling MD,Gee TS,Cunningham IB,Burchenal JH

    更新日期:1975-08-01 00:00:00

  • Non-Hodgkin's lymphoma in children. A comparative study of two modalities of therapy.

    abstract::Eighty-six children with non-Hodgkin's lymphoma were studied from 1964 to January 31, 1975. Seventy-six percent of the 43 patients in the nonprotocol group had far advanced disease, and 76% had Rappaport's diffuse histology. Only 11% of these patients survived free of disease. The second group of 43 patients received ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197601)37:1<123::aid-cncr2820370

    authors: Wollner N,Burchenal JH,Lieberman PH,Exelby P,D'Angio G,Murphy ML

    更新日期:1976-01-01 00:00:00

  • A phase I study to assess the feasibility and oncologic safety of axillary reverse mapping in breast cancer patients.

    abstract:BACKGROUND:Axillary reverse mapping (ARM) is a novel technique to preserve upper extremity lymphatics that may reduce the incidence of lymphedema after axillary lymph node dissection. Early reports have suggested that ARM lymph nodes do not contain metastatic disease from breast cancer; however, these studies were cond...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25096

    authors: Bedrosian I,Babiera GV,Mittendorf EA,Kuerer HM,Pantoja L,Hunt KK,Krishnamurthy S,Meric-Bernstam F

    更新日期:2010-06-01 00:00:00

  • The prognostic significance of sialyl-Tn antigen in women treated with breast carcinoma treated with adjuvant chemotherapy.

    abstract:BACKGROUND:Sialyl-Tn (STn) represents an aberrantly glycosylated mucin epitope that is expressed in breast carcinoma and other adenocarcinomas and is an important factor in the development of novel immunotherapeutic approaches. The primary aim of the current study was to investigate the influence of STn expression on t...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/(sici)1097-0142(19971215)80:12<2240::aid-c

    authors: Kinney AY,Sahin A,Vernon SW,Frankowski RF,Annegers JF,Hortobagyi GN,Buzdar AU,Frye DK,Dhingra K

    更新日期:1997-12-15 00:00:00

  • Racial disparities and survival for nonsmall-cell lung cancer in a large cohort of black and white elderly patients.

    abstract:BACKGROUND:This study aimed to examine disparities in survival and associated factors for patients with nonsmall-cell lung cancer (NSCLC) and to determine whether racial disparities varied over time (1991-1995, 1996-1999, and 2000-2002). METHODS:The authors studied 70,901 patients aged>or=65 years with stage I-IV NSCL...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.24521

    authors: Hardy D,Xia R,Liu CC,Cormier JN,Nurgalieva Z,Du XL

    更新日期:2009-10-15 00:00:00

  • Pituitary adenomas. Immunocytochemical study of 150 tumors with clinicopathologic correlation.

    abstract::Retrospective immunocytochemical study of prolactin, growth hormone, ACTH, TSH and gonadotropins was performed on 150 pituitary adenomas from 142 patients and the results were correlated with clinical manifestations. There were 60 prolactin-positive tumors, 13 growth hormone-positive tumors, nine ACTH-positive tumors ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830815)52:4<648::aid-cncr28205

    authors: Mukai K

    更新日期:1983-08-15 00:00:00

  • Hemoccult screening in selected patients. The hernia patient older than age fifty years.

    abstract::Two hundred and forty patients, asymptomatic relative to gastrointestinal disease, who applied for elective hernia repair, were tested as outpatients for occult blood in the stool. Thirty-eight patients had one or more positive specimens. Significant pathologic characteristics were identified by lower gastrointestinal...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830401)51:7<1261::aid-cncr2820

    authors: Morris DM,Daron PB,Goldman LI

    更新日期:1983-04-01 00:00:00

  • Bendamustine: a new look at an old drug.

    abstract::Alkylating agents form the basis of most combination treatment regimens for low-grade lymphoproliferative disorders. Bendamustine is a unique alkylating agent that has distinctive preclinical activity in cell lines resistant to other alkylators. Furthermore, clinical activity has been demonstrated in patients with alk...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.24057

    authors: Kalaycio M

    更新日期:2009-02-01 00:00:00

  • Radiation-adriamycin interactions: preliminary clinical observations.

    abstract::This communication reports four patients treated with the anthracycline adriamycin and irradiation either concurrently or sequentially, who demonstrated apparent augumentation of radiation reactions. Two of these patients demonstrated the so-called "recall" phenomenon. ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197509)36:3<946::aid-cncr2820360

    authors: Cassady JR,Richter MP,Piro AJ,Jaffe N

    更新日期:1975-09-01 00:00:00

  • Sunitinib-induced hyperparathyroidism: a possible mechanism to altered bone homeostasis.

    abstract:BACKGROUND:Sunitinib malate is an orally bioavailable tyrosine kinase inhibitor that is active against many tyrosine kinase receptors involving crucial pathways in both healthy tissues and malignant tissues. Because its use in clinical practice is quite recent, many of its possible side effects remain unknown. In this ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26435

    authors: Baldazzi V,Tassi R,Lapini A,Lunghi A,Garofoli E,Caruso S,Carini M,Mazzanti R

    更新日期:2012-06-15 00:00:00