Interaction of molecular alterations with immune response in melanoma.

abstract：:A nonfunctioning strumal carcinoid arising in a 49-year-old woman was studied by histochemical and immunocytochemical techniques. All tumor cells, irrespective of their architectural arrangement, showed properties of neuroendocrine-programmed cells, without any evidence of thyroid follicular cell differentiation. Foci...

journal_title：Cancer

authors： Dayal Y,Tashjian AH Jr,Wolfe HJ

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine whether a very low presenting prostate-specific antigen (PSA) level was associated with greater prostate cancer-specific mortality (PCSM) among men with a Gleason score (GS) of 8 to 10. METHODS:The Surveillance, Epidemiology, and End Results program was used to i...

journal_title：Cancer

authors： Mahal BA,Aizer AA,Efstathiou JA,Nguyen PL

更新日期：2016-01-01 00:00:00

abstract：:The cytogenetic findings in 31 liposarcomas from 26 patients are reported. Four other tumors did not grow. Three histologic types are represented in this analysis. The well-differentiated liposarcomas were characterized by telomeric associations, large marker chromosomes and ring chromosomes, and in some cases, double...

journal_title：Cancer

authors： Sreekantaiah C,Karakousis CP,Leong SP,Sandberg AA

更新日期：1992-05-15 00:00:00

abstract：:A rare case of malignant fibrous histiocytoma of the aorta is reported. Review of the literature revealed that primary tumors of the aorta are exclusively mesenchymal tumors that almost invariably pursue a fatal course. ...

journal_title：Cancer

authors： Chen KT

更新日期：1981-08-01 00:00:00

abstract：:Patients with Philadelphia chromosome-positive chronic myelogenous leukemia (CML) were treated with a combination of alpha-interferon and gamma-interferon. Recombinant alpha-2a-interferon (Roferon-A, Hoffmann-LaRoche, Inc., Nutley, NJ) and recombinant gamma-interferon (Genentech, Inc., South San Francisco, CA) were ad...

journal_title：Cancer

authors： Talpaz M,Kurzrock R,Kantarjian H,Rothberg J,Saks S,Evans L,Gutterman JU

更新日期：1991-11-15 00:00:00

abstract：BACKGROUND:The diagnosis of low-grade squamous intraepithelial lesion (LSIL), cannot exclude high-grade squamous intraepithelial lesion (LSIL-H) was not included in the 2001 Bethesda System. It is used in some institutions to diagnose cases that fulfill criteria for both the diagnosis of LSIL and atypical squamous cell...

journal_title：Cancer

authors： Alsharif M,Kjeldahl K,Curran C,Miller S,Gulbahce HE,Pambuccian SE

更新日期：2009-04-25 00:00:00

abstract：BACKGROUND:Colorectal cancer patients undergoing chemotherapy (CT) are likely to experience multiple concurrent toxicities that, rather than appearing singularly, may be associated with one another. Graphic and tabular representations of distance matrices were used to identify associations between toxicities and to def...

journal_title：Cancer

authors： Aprile G,Ramoni M,Keefe D,Sonis S

更新日期：2008-01-15 00:00:00

abstract：:The authors retrospectively searched for human papillomavirus (HPV) types 16 and 18 in 60 cases of carcinoma arising from the nasal cavities (NC) and paranasal sinuses (PS) by using the polymerase chain reaction (PCR) on DNA extracted from formalin-fixed, paraffin-embedded tissues. In cases of SCC (n = 49), the author...

journal_title：Cancer

authors： Furuta Y,Takasu T,Asai T,Shinohara T,Sawa H,Nagashima K,Inuyama Y

更新日期：1992-01-15 00:00:00

abstract：:Antibodies to herpes simplex viral-induced antigens (HSVIA) were assayed by an indirect immunofluorescent technique in 93 regular cigarette smokers, 75 of whom also imbibed alcoholic beverages. Controls were 94 nonsmoking, nondrinking volunteers matched with the smoker for age and sex. IgA antibodies to HSVIA were det...

journal_title：Cancer

authors： Smith HG,Horowitz N,Silverman NA,Henson DE,Chretien PB

更新日期：1976-09-01 00:00:00

abstract：:A case of carcinoid tumor of the gallbladder associated with adenocarcinoma in a 56-year-old man is reported and a review of the literature is made. The tumor was a polypoid mass with a size of 5.5 X 4.0 X 2.8 cm. Histologically, the tumor showed carcinoid and adenocarcinoma with areas of mucous change. Tumor cells co...

journal_title：Cancer

authors： Wada A,Ishiguro S,Tateishi R,Ishikawa O,Matsui Y

更新日期：1983-05-15 00:00:00

abstract：:One hundred eighty-three patients with malignant skeletal (83) or soft tissue sarcoma (100) were entered into the multimodality preoperative limb salvage protocol. Local recurrences were observed in 5 of 183 (2.7%). Six patients required amputation because of complications, and 13 patients died within 1 year from meta...

journal_title：Cancer

authors： Eilber FR,Morton DL,Eckardt J,Grant T,Weisenburger T

更新日期：1984-06-15 00:00:00

abstract：:A case of basosquamous or so-called transitional cloacogenic carcinoma of the sigmoid colon, which arose above the pelvic brim at the peritoneal reflection, is reported. We were not able to find a report of this histologic type of tumor arising this far from the pectinate line of the anus, which is the most common pri...

journal_title：Cancer

authors： Strate RW,Richardson JD,Bannayan GA

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Strumal carcinoids (SC) are ovarian tumors containing thyroid parenchyma admixed with carcinoid elements. Microscopically, the carcinoid component of SC usually presents a ribbon or trabecular pattern similar to the pattern exhibited by hindgut carcinoids. The authors designed an immunohistochemical study to...

journal_title：Cancer

authors： Sidhu J,Sánchez RL

更新日期：1993-09-01 00:00:00

abstract：:The effect of cis-diamminedichloroplatinum II (DDP) and ionizing radiation on human bladder transitional cell carcinoma (TCC) was evaluated in nude mouse-grown human tumors following administration of single-agent and combination treatment. Combination of DDP and radiation resulted in accelerated tumor regression and ...

journal_title：Cancer

authors： Kyriazis AP,Yagoda A,Kereiakes JG,Kyriazis AA,Whitmore WF Jr

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:There is limited understanding of the association between barriers to care and clinical outcomes within patient navigation programs. METHODS:Secondary analyses of data from the intervention arms of the Patient Navigation Research Program were performed, which included navigated participants with abnormal br...

journal_title：Cancer

authors： Ramachandran A,Snyder FR,Katz ML,Darnell JS,Dudley DJ,Patierno SR,Sanders MR,Valverde PA,Simon MA,Warren-Mears V,Battaglia TA,Patient Navigation Research Program Investigators.

更新日期：2015-11-15 00:00:00

abstract：:It is justifiable to assume that a spontaneous regression of cervical intraepithelial neoplasia is in progress when pathologic epithelium is replaced by normal epithelium. Very rare histologic pictures of this process are shown. Dysplastic squamous epithelium or intraepithelial carcinomas become detached from their ba...

journal_title：Cancer

authors： Bajardi F

更新日期：1984-08-15 00:00:00

abstract：:Grilled or fried meat and fish contain various mutagenic heterocyclic amines, and structures of at least 19 compounds have already been determined. Among these, 10 have been examined for long term carcinogenicity, all proving to be positive. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), for example, preferen...

journal_title：Cancer

authors： Nagao M,Ushijima T,Wakabayashi K,Ochiai M,Kushida H,Sugimura T,Hasegawa R,Shirai T,Ito N

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Widespread disparities in care have been documented in women with gynecologic cancer in the United States. This study was designed to determine whether structural barriers to optimal care were present during the preoperative period for patients with gynecologic cancer. METHODS:A retrospective review was con...

journal_title：Cancer

authors： Frey MK,Moss HA,Musa F,Rolnitzky L,David-West G,Chern JY,Boyd LR,Curtin JP

更新日期：2016-03-15 00:00:00

abstract：BACKGROUND:Malignant lymphomas and solid tumors that mimic or are associated with epithelioid granulomas are widely recognized in surgical pathology, but have received little attention in the cytopathology literature. In this study the authors present their experience with six such cases in which the presence of granul...

journal_title：Cancer

authors： Khurana KK,Stanley MW,Powers CN,Pitman MB

更新日期：1998-04-25 00:00:00

abstract：BACKGROUND:Recent studies revealed that incidence rates of cutaneous melanoma (CM) were leveling off predominantly among younger people and patterns suggested birth-cohort effects. The current study analyzed the development of prognostic factors and survival in incident CM over 25 years. METHODS:All 45,483 patients wi...

journal_title：Cancer

authors： Buettner PG,Leiter U,Eigentler TK,Garbe C

更新日期：2005-02-01 00:00:00

abstract：:Seventeen patients with carcinoma confined to the pancreas and the peripancreatic area received preoperative radiation therapy in an attempt to increase the resectability rate and to reduce the incidence of recurrence. The tumors were considered either unresectable or of borderline resectability. The radiation dose ra...

journal_title：Cancer

authors： Pilepich MV,Miller HH

更新日期：1980-11-01 00:00:00

abstract：:Quality indicators applicable to cancer end-of-life care exist, but have not been widely implemented. To advance this field, the authors worked with the Agency for Health Care Research and Quality and the National Cancer Institute to organize a national symposium to discuss key issues and future goals, based on a conc...

journal_title：Cancer

authors： Seow H,Snyder CF,Shugarman LR,Mularski RA,Kutner JS,Lorenz KA,Wu AW,Dy SM

更新日期：2009-09-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) has several potential uses in bone marrow transplantation. Most often IVIG is used to modify cytomegalovirus (CMV) infection or CMV-related interstitial pneumonia. It also is used to modify graft versus host disease (GVHD) and decrease infections other than CMV. Another use is to trea...

journal_title：Cancer

authors： Gale RP,Winston D

更新日期：1991-09-15 00:00:00

abstract：BACKGROUND:Cervical carcinoma remains a significant health risk for the older woman. In the current study the yield of screening of mature women in an established, opportunistic screening program was examined. Strategies for improving screening in this age group were identified through examination of recent Pap test hi...

journal_title：Cancer

authors： Colgan TJ,Clarke A,Hakh N,Seidenfeld A

更新日期：2002-08-25 00:00:00

abstract：:Breast cancer is serious public health problem in countries of all resource levels. Although major advances in the detection and treatment of the disease have occurred in higher income settings, similar progress has been slow or scarce in most low- and middle-income countries (LMCs). The poorer outcomes in LMCs may re...

journal_title：Cancer

authors： Harford J,Azavedo E,Fischietto M,Breast Health Global Initiative Healthcare Systems Panel.

更新日期：2008-10-15 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor receptor (c-met), autocrine motility factor receptor (AMFR), and urokinase-type plasminogen activator receptor (uPAR) are known to play important roles in tumor cell migration, invasion, and metastasis. The authors studied the relation between the expression patterns of these genes a...

journal_title：Cancer

authors： Taniguchi K,Yonemura Y,Nojima N,Hirono Y,Fushida S,Fujimura T,Miwa K,Endo Y,Yamamoto H,Watanabe H

更新日期：1998-06-01 00:00:00

abstract：:Previous studies have indicated that OK-432 is a potent biologic response modifier (BRM) and that it augments immune responses to tumor cells. We studied the direct effect of OK-432 on tumor cells. Established and freshly derived human ovarian carcinoma lines were examined for their susceptibility to OK-432 or its sub...

journal_title：Cancer

authors： Nio Y,Zighelboim J,Berek J,Bonavida B

更新日期：1989-07-15 00:00:00

abstract：BACKGROUND:Crizotinib is a tyrosine kinase inhibitor active against ALK, MET, and ROS1. We previously reported that crizotinib decreases testosterone in male patients. The detailed etiology of the effect, its symptomatic significance, and the effectiveness of subsequent testosterone replacement have not been previously...

journal_title：Cancer

authors： Weickhardt AJ,Doebele RC,Purcell WT,Bunn PA,Oton AB,Rothman MS,Wierman ME,Mok T,Popat S,Bauman J,Nieva J,Novello S,Ou SH,Camidge DR

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Based on previous data demonstrating a potentially synergistic interaction between tamoxifen and cisplatin in metastatic melanoma therapy, a Phase II study was performed to assess the activity of tamoxifen, etoposide, mitoxantrone, and cisplatin (TEMP) in patients with metastatic breast carcinoma. METHODS:F...

journal_title：Cancer

authors： Conzen SD,Kaufman PA,Arvizu C,LeMarbre P,Maurer LH,Mott LA,Mills LE

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:China's lung cancer (LC) burden plays a pivotal role in the global cancer epidemic. Comparing LC burden and population attributable fractions (PAFs) of risk factors between China and other countries/regions is essential to inform effective intervention. The Global Burden of Disease (GBD) study provides a uni...

journal_title：Cancer

authors： Wang N,Mengersen K,Tong S,Kimlin M,Zhou M,Hu W

更新日期：2020-09-15 00:00:00