DTIC, CCNU, bleomycin and vincristine (BOLD) in metastatic melanoma.

abstract：BACKGROUND:The clinical value of DNA flow cytometry of colorectal cancer is unclear. The purpose of this retrospective study was to evaluate the relationship between tumor flow cytometry, histopathologic parameters, and survival. METHODS:Flow cytometry was performed on paraffin embedded specimens from 653 patients who...

journal_title：Cancer

authors： Tang R,Ho YS,You YT,Hsu KC,Chen JS,Changchien CR,Wang JY

更新日期：1995-11-15 00:00:00

abstract：:Low-dose continuous infusion 5-fluorouracil (LDCI-FU) was administered to 28 women with advanced breast carcinoma. Daily doses ranged from 175 to 250 mg/m2. The LDCI-FU was delivered continuously until the appearance of toxicity and was reinstituted at a 20% dose reduction after toxicity completely resolved. Patients ...

journal_title：Cancer

authors： Huan S,Pazdur R,Singhakowinta A,Samal B,Vaitkevicius VK

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Stenotrophomonas maltophilia is responsible for an increasing number of infections, especially in hospitalized patients. Therapy options are limited and trimethoprim/sulfamethoxazole (TMP/SMX) is often the main treatment option for this infection. In the current study, the risk factors were determined for th...

journal_title：Cancer

authors： Ansari SR,Hanna H,Hachem R,Jiang Y,Rolston K,Raad I

更新日期：2007-06-15 00:00:00

abstract：BACKGROUND:Melanoma vaccine treatment appears to slow the progression of melanoma in some patients, particularly in patients in whom it stimulates cellular antimelanoma immune responses. The relationship of vaccine-induced antibody responses to clinical outcome is less clear. The purpose of this study was to investigat...

journal_title：Cancer

authors： Miller K,Abeles G,Oratz R,Zeleniuch-Jacquotte A,Cui J,Roses DF,Harris MN,Bystryn JC

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:Curative resection does not guarantee long term survival for the patient with extrahepatic bile duct carcinoma because of the possibility of metastases to the liver (LM). Expression of mucin core protein-1 (MUC1), sialyl-Le(x), and sialosyl-Tn in bile duct carcinoma was determined and compared with LM and pr...

journal_title：Cancer

authors： Takao S,Uchikura K,Yonezawa S,Shinchi H,Aikou T

更新日期：1999-11-15 00:00:00

abstract：BACKGROUND:Cancer and its treatment lead to increased financial distress for patients. To the authors' knowledge, to date, no standardized patient-reported outcome measure has been validated to assess this distress. METHODS:Patients with AJCC Stage IV solid tumors receiving chemotherapy for at least 2 months were recr...

journal_title：Cancer

authors： de Souza JA,Yap BJ,Wroblewski K,Blinder V,Araújo FS,Hlubocky FJ,Nicholas LH,O'Connor JM,Brockstein B,Ratain MJ,Daugherty CK,Cella D

更新日期：2017-02-01 00:00:00

abstract：:The unusual course of a lymphoma in a woman with a chromosome abnormality is reported. When aged 30 years, the right lobe of her thyroid gland was found to be infiltrated by a follicular lymphoma. Two years later, poorly differentiated diffuse lymphoctic lymphoma recurred locally, grew rapidly, and infiltrated the adj...

journal_title：Cancer

authors： Langlands AO,MacLean N

更新日期：1976-07-01 00:00:00

abstract：:The histologic findings of five patients with clinically typical Bowenoid dysplasia (BD) allowed the authors to classify the vulvar and perineal biopsies of 18 patients under 40 years as BD and the vulvar biopsies of six patients under 40 years as squamous cell carcinoma in situ (CIS). The two best criteria for BD are...

journal_title：Cancer

authors： Ulbright TM,Stehman FB,Roth LM,Ehrlich CE,Ransburg RC

更新日期：1982-12-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of the rapamycin (mTOR) signaling pathway represents a promising target for cancer therapy. The phosphorylation status of Akt and of mTOR's phosphorylation target eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) is often used to assess the activity of Akt and mTOR signaling...

journal_title：Cancer

authors： Akcakanat A,Sahin A,Shaye AN,Velasco MA,Meric-Bernstam F

更新日期：2008-06-01 00:00:00

abstract：:Chlorozotocin was administered by rapid intravenous infusion to 35 patients with advanced cancer on either single-day of five-consecutive-day schedules. Total doses per course ranged from 12.5 to 200 mg/m2. On either administration schedule, dose limiting toxicities were thrombocytopenia and leukopenia at total doses ...

journal_title：Cancer

authors： Kovach JS,Moertel CG,Schutt AJ,Frytak S,O'Connell MJ,Rubin J,Ingle JN

更新日期：1979-06-01 00:00:00

abstract：:The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) of the Centers for Disease Control and Prevention (CDC) is implemented through cooperative agreements with state health departments, US territories, and tribal health organizations (grantees). Grantees typically contract with clinicians and othe...

journal_title：Cancer

authors： Yancy B,Royalty JE,Marroulis S,Mattingly C,Benard VB,DeGroff A

更新日期：2014-08-15 00:00:00

abstract：:The effect of cyclophosphamide (CY) on ovarian function was studied in patients with breast cancer receiving prolonged daily administration of this agent (100 mg/day) after radical surgery. Out of 18 premenopausal patients that received 8.4-39.9 g CY, 15 developed permanent amenorrhea. The average dose given before th...

journal_title：Cancer

authors： Koyama H,Wada T,Nishizawa Y,Iwanaga T,Aoki Y

更新日期：1977-04-01 00:00:00

abstract：:Six patients with Hodgkin's disease who developed idiopathic thrombocytopenic purpura (ITP) are presented. In contrast to prior cases reported in the literature, none of these patients developed recurrent Hodgkin's disease at the time of or subsequent to their thrombocytopenia, with follow-up data available up to 10 y...

journal_title：Cancer

authors： Cohen JR

更新日期：1978-02-01 00:00:00

abstract：:This study sought to replicate and expand findings reported by the National Surgical Adjuvant Breast and Bowel Project (NSABP) on prognostic factors in resectable colon cancer. Mantel-Haenszel tests and the Cox model were used to analyze prognostic significance and effect of primary disease symptoms and tumor location...

journal_title：Cancer

authors： Steinberg SM,Barkin JS,Kaplan RS,Stablein DM

更新日期：1986-05-01 00:00:00

abstract：:The value of the serum level of carcinoembryonic antigen (CEA) as an indicator of recurrent colorectal carcinoma has been accepted, and the use of serial CEA levels to monitor postoperative chemotherapy has been suggested, However, elevated CEA levels may be associated with nonneoplastic conditions, of which the most ...

journal_title：Cancer

authors： Savrin RA,Martin EW Jr

更新日期：1981-02-01 00:00:00

abstract：:Flow cytometric analysis of nuclear DNA content was performed on excised malignant tissue of the esophagus. The DNA ploidy pattern was compared with a variety of histologic parameters and the subsequent clinical course to determine whether or not this pattern is associated with the mode of malignant potentiality. Of t...

journal_title：Cancer

authors： Kaketani K,Saito T,Kobayashi M

更新日期：1989-08-15 00:00:00

abstract：BACKGROUND:Optimal treatments for vulvar and vaginal melanomas (VVMs) have not been identified. Herein, the authors compare molecular profiles between VVM and nongynecologic melanoma (NGM) subtypes with the objective of identifying novel, targetable biomarkers. METHODS:In total, 2304 samples of malignant melanoma that...

journal_title：Cancer

authors： Hou JY,Baptiste C,Hombalegowda RB,Tergas AI,Feldman R,Jones NL,Chatterjee-Paer S,Bus-Kwolfski A,Wright JD,Burke WM

更新日期：2017-04-15 00:00:00

abstract：BACKGROUND:Rural residence has been associated with increased risk of late stage cancer diagnosis, but it is unknown if this is related to lower socioeconomic status (SES) of rural residents or to other factors. This study examined the impacts of SES and urban/rural status on colorectal cancer (CRC) stage at diagnosis ...

journal_title：Cancer

authors： Parikh-Patel A,Bates JH,Campleman S

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Insular thyroid carcinoma was described originally as a tumor with aggressive behavior. However, whether a predominant insular component is an independent factor for poor prognosis is unclear. METHODS:The authors compared the clinical behavior of tumors in three groups of patients with thyroid carcinoma--13...

journal_title：Cancer

authors： Pellegriti G,Giuffrida D,Scollo C,Vigneri R,Regalbuto C,Squatrito S,Belfiore A

更新日期：2002-11-15 00:00:00

abstract：BACKGROUND:Intralesional radioimmunotherapy (RAIT) may improve the management of malignant gliomas whose prognosis is, at present, very poor. Current treatment modalities (e.g., surgery, radiotherapy, and chemotherapy) may prolong survival by a few months but cannot prevent tumor recurrence. METHODS:Following one or m...

journal_title：Cancer

authors： Riva P,Arista A,Tison V,Sturiale C,Franceschi G,Spinelli A,Riva N,Casi M,Moscatelli G,Frattarelli M

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The authors have previously reported a tumor cell vaccine modified with superantigen staphylococcal enterotoxin A (SEA) and its antitumor effect. The tumor cell vaccines modified with multiple immune activators frequently elicited stronger immune responses against established tumors than single-modified vacc...

journal_title：Cancer

authors： Yi P,Yu H,Ma W,Wang Q,Minev BR

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The use of docetaxel prolongs survival for patients with castrate-resistant prostate cancer (CRPC). Inhibition of vascular endothelial growth factor (VEGF) with bevacizumab may further enhance the antitumor effect of docetaxel and estramustine in patients with CRPC. METHODS:This cooperative group trial enro...

journal_title：Cancer

authors： Picus J,Halabi S,Kelly WK,Vogelzang NJ,Whang YE,Kaplan EB,Stadler WM,Small EJ,Cancer and Leukemia Group B.

更新日期：2011-02-01 00:00:00

abstract：:The case history of a woman with a "female adnexal tumor of probable Wolffian origin" is described in which the neoplasm recurred three times during a 16-year interval and responded with prolonged remission after repeated surgical excision and radiotherapy. Ultrastructural data are given to support the Wolffian nature...

journal_title：Cancer

authors： Brescia RJ,Cardoso de Almeida PC,Fuller AF Jr,Dickersin GR,Robboy SJ

更新日期：1985-09-15 00:00:00

abstract：BACKGROUND:A previous comparative tissue proteomics study by the authors of the current study led to the identification of caldesmon (CaD) as one of the proteins associated with cervical metastasis of oral cavity squamous cell carcinoma (OSCC). In the current investigation, the authors focused on the potential function...

journal_title：Cancer

authors： Chang KP,Wang CL,Kao HK,Liang Y,Liu SC,Huang LL,Hseuh C,Hsieh YJ,Chien KY,Chang YS,Yu JS,Chi LM

更新日期：2013-11-15 00:00:00

abstract：BACKGROUND:American Indians and Alaska Natives (AI/AN) experience higher morbidity and mortality from primary liver cancer than other United States (US) populations, but racial misclassification in medical records results in underestimates of disease burden. METHODS:To reduce misclassification, National Program of Can...

journal_title：Cancer

authors： Jim MA,Perdue DG,Richardson LC,Espey DK,Redd JT,Martin HJ,Kwong SL,Kelly JJ,Henderson JA,Ahmed F

更新日期：2008-09-01 00:00:00

abstract：:A nonfunctioning strumal carcinoid arising in a 49-year-old woman was studied by histochemical and immunocytochemical techniques. All tumor cells, irrespective of their architectural arrangement, showed properties of neuroendocrine-programmed cells, without any evidence of thyroid follicular cell differentiation. Foci...

journal_title：Cancer

authors： Dayal Y,Tashjian AH Jr,Wolfe HJ

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Carboplatin-based regimens have demonstrated activity in pediatric patients with low-grade glioma (LGG). However, carboplatin hypersensitivity reaction (Cb HSR) represents a common and limiting factor for the continuation of therapy. METHODS:The objectives of this study were to describe the prevalence, char...

journal_title：Cancer

authors： Lafay-Cousin L,Sung L,Carret AS,Hukin J,Wilson B,Johnston DL,Zelcer S,Silva M,Odame I,Mpofu C,Strother D,Bouffet E

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:Hypothyroidism is a potential complication after radiation therapy (RT) when treatment fields include the thyroid. The authors assessed risk of hypothyroidism in breast cancer patients who were receiving RT to a supraclavicular field, which typically includes a portion of thyroid. METHODS:The authors identi...

journal_title：Cancer

authors： Smith GL,Smith BD,Giordano SH,Shih YC,Woodward WA,Strom EA,Perkins GH,Tereffe W,Yu TK,Buchholz TA

更新日期：2008-03-15 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the clinical characteristics, treatment response, and frequency of p53 overexpression in Ashkenazi Jewish women with hereditary ovarian carcinoma. METHODS:Seventy-one Jewish women with epithelial ovarian carcinoma (EOC) were tested for the three BRCA founder muta...

journal_title：Cancer

authors： Cass I,Baldwin RL,Varkey T,Moslehi R,Narod SA,Karlan BY

更新日期：2003-05-01 00:00:00

abstract：:Although the conference could not provide a definitive etiologic explanation for the observed increase in incidence of human brain tumors, particularly among the elderly, nevertheless, this interdisciplinary gathering of prominent scientists and clinicians proved invaluable in identifying new avenues of research. Clea...

journal_title：Cancer

authors： Brem S,Rozental JM,Moskal JR

更新日期：1995-08-15 00:00:00