Prognostic indicators of colon tumors. The Gastrointestinal Tumor Study Group experience.

abstract：BACKGROUND:US breast cancer mortality is declining, but thousands of women still die each year. METHODS:Two established simulation models examine 6 strategies that include increased screening and/or treatment or elimination of obesity versus continuation of current patterns. The models use common national data on inci...

journal_title：Cancer

authors： Mandelblatt J,van Ravesteyn N,Schechter C,Chang Y,Huang AT,Near AM,de Koning H,Jemal A

更新日期：2013-07-15 00:00:00

abstract：:Delayed cutaneous hypersensitivity to 2,3-dinitrochlorobenzene (DNCB) was tested in 419 patients with malignant melanoma to determine whether DNCB reactivity was associated with prognosis. At the time of definitive surgery, a positive DNCB test was seen in 82% of the patients in State I (regional lymph node histologic...

journal_title：Cancer

authors： Camacho ES,Pinsky CM,Braun DW Jr,Golbey RB,Fortner JG,Wanebo HJ,Oettgen HF

更新日期：1981-05-15 00:00:00

abstract：:Sixty percent of all cancer occurs in persons aged > or =65 years. This article provides an overview of aspects of the burden of cancer in the elderly, highlighting certain demographic and epidemiologic data. It served as a frame of reference for participants in the Oncology Geriatric Education Retreat, San Juan, Puer...

journal_title：Cancer

authors： Yancik R

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Inactivation of the tumor suppressor gene PTEN/MMAC1/TEP1, located on chromosome 10q23, is a common event in advanced stages of diverse human malignancies. However, the prognostic role of PTEN expression in patients with hepatocellular carcinoma (HCC) has not been characterized. METHODS:One hundred five res...

journal_title：Cancer

authors： Hu TH,Huang CC,Lin PR,Chang HW,Ger LP,Lin YW,Changchien CS,Lee CM,Tai MH

更新日期：2003-04-15 00:00:00

abstract：BACKGROUND:Epithelioid sarcoma is a highly malignant soft tissue tumor that is largely resistant to conventional chemotherapy and radiotherapy. Because paclitaxel has been proven to be effective in other human malignancies refractory to conventional chemotherapy, the authors analyzed the in vitro growth inhibitory effe...

journal_title：Cancer

authors： Reinecke P,Knopf C,Schmitz M,Schneider EM,Gabbert HE,Gerharz CD

更新日期：2000-04-01 00:00:00

abstract：:A clinicopathologic study of 48 cases of pleomorphic lipoma from the files of the Armed Forces Institute of Pathology reveals that this tumor occurs principally in males (83%) in the fifth to seventh decades (mean 57 years) and shows a predilection for the posterior neck, shoulder, and back. Typically, the lesion appe...

journal_title：Cancer

authors： Shmookler BM,Enzinger FM

更新日期：1981-01-01 00:00:00

abstract：:The establishment of a maturation-induction model using human colon cancer cells as targets is reported. Two colon carcinoma cell lines were established from human tumors; one line was heterogeneous and was cloned into two distant subpopulations. Cells from these lines and clones and cells from an established human co...

journal_title：Cancer

authors： Dexter DL,Hager JC

更新日期：1980-03-15 00:00:00

abstract：BACKGROUND:Previous reports based on small patient numbers suggested that changes in serum HER-2/neu levels may predict response or lack of response to trastuzumab-based therapies in metastatic breast cancer (MBC). The objectives of this study were to pool data from 307 patients with MBC from 7 medical institutions to ...

journal_title：Cancer

authors： Ali SM,Carney WP,Esteva FJ,Fornier M,Harris L,Köstler WJ,Lotz JP,Luftner D,Pichon MF,Lipton A,Serum HER-2\/neu Study Group.

更新日期：2008-09-15 00:00:00

abstract：:To determine whether the referral of lung cancer patients to university cancer centers was related to nonclinical factors, the medical charts were reviewed for almost all lung cancer patients diagnosed during the period of 1973-1976 in New Hampshire and Vermont. Greater distance from a cancer center, lower functional ...

journal_title：Cancer

authors： Greenberg ER,Dain B,Freeman D,Yates J,Korson R

更新日期：1988-10-15 00:00:00

abstract：BACKGROUND:Early stage lung cancer has a variable prognosis, and there are currently no markers that predict which patients will recur. This study examined the relation between tumor-regulatory T (Treg) cells and total tumor-infiltrating T-cell lymphocytes (TIL) to determine whether they correlated with recurrence. ME...

journal_title：Cancer

authors： Petersen RP,Campa MJ,Sperlazza J,Conlon D,Joshi MB,Harpole DH Jr,Patz EF Jr

更新日期：2006-12-15 00:00:00

abstract：BACKGROUND:Children diagnosed with medulloblastoma whose tumor involves the brain stem or has spread through the cerebrospinal fluid pathways to other areas of the brain or spinal cord have a poor prognosis despite therapy with surgery, craniospinal irradiation (CSI), and chemotherapy. Preradiation chemotherapy may imp...

journal_title：Cancer

authors： Mosijczuk AD,Nigro MA,Thomas PR,Burger PC,Krischer JP,Morantz RA,Kurdunowicz B,Mulne AF,Towbin RB,Freeman AI

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Bloody nipple discharge is a significant clue in the detection of ductal carcinoma of the breast. In the past, pathologic diagnoses were obtained exclusively via excision, but recently developed mammoscopic techniques have been found to yield valuable information relating to the diagnosis of intraductal lesi...

journal_title：Cancer

authors： Matsunaga T,Kawakami Y,Namba K,Fujii M

更新日期：2004-11-15 00:00:00

abstract：BACKGROUND:Hepatectomy is the standard of care for patients with colorectal cancer who have isolated hepatic metastases; however, the long-term survival benefits of hepatectomy in this population have not been characterized well outside of case series. For the current study, a population-based database was used to comp...

journal_title：Cancer

authors： Cummings LC,Payes JD,Cooper GS

更新日期：2007-02-15 00:00:00

abstract：:This clinicopathologic study concerns 27 cases of "dedifferentiated" soft tissue sarcoma (DSTS), including 14 liposarcomas, six leiomyosarcomas, five chondrosarcomas, and two rhabdomyosarcomas. In addition, the authors conducted an immunohistochemical survey of 23 cases and an electron microscopic examination of three...

journal_title：Cancer

authors： Hashimoto H,Daimaru Y,Tsuneyoshi M,Enjoji M

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Compared with free drug, sterically stabilized liposomal drug has prolonged circulation time and, thereby, higher tumor selectivity and antitumor activity. The stability in plasma is an important consideration in the formulation of clinically useful liposomal drug. A Phase I study of a stable liposomal doxor...

journal_title：Cancer

authors： Hong RL,Tseng YL

更新日期：2001-05-01 00:00:00

abstract：:The German Society of Pediatric Oncology in 1981 initiated the Cooperative Ewing's Sarcoma Study (CESS 81) using a four-drug combination of chemotherapy prior to definitive local control with surgery and/or radiation. From January 1, 1981 until February 28, 1985, 93 patients were registered at the trial office from 54...

journal_title：Cancer

authors： Jürgens H,Exner U,Gadner H,Harms D,Michaelis J,Sauer R,Treuner J,Voûte T,Winkelmann W,Winkler K

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:We sought to identify the costs of adjuvant therapies following radical prostatectomy (RP) and factors associated with their receipt. METHODS:We used SEER-Medicare data from 2004-2006 to identify 4247 men who underwent RP, of whom 600 subsequently received adjuvant therapies. We used Cox regression to ident...

journal_title：Cancer

authors： Williams SB,Gu X,Lipsitz SR,Nguyen PL,Choueiri TK,Hu JC

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Radiofrequency thermal ablation (RFA) is a new minimally invasive treatment for localized cancer. Minimally invasive surgical options require less resources, time, recovery, and cost, and often offer reduced morbidity and mortality, compared with more invasive methods. To be useful, image-guided, minimally i...

journal_title：Cancer

authors： Wood BJ,Ramkaransingh JR,Fojo T,Walther MM,Libutti SK

更新日期：2002-01-15 00:00:00

abstract：BACKGROUND:The objective of this analysis was to evaluate the role of autologous stem cell transplantation (ASCT) in prolonging disease free survival (DFS) and overall survival (OS) in patients with chronic myeloid leukemia (CML) who received autografts of Philadelphia chromosome (Ph) positive or Ph negative cell harve...

journal_title：Cancer

authors： Koziner B,Dengra C,Lucero G,Klein G,Cánepa C,Milovic V,Milone G,Robinson A,Cerutti I,Saporito G,Kusminsky G,Milone J,Bordone J,Lastiri F,Argentine Group of Bone Marrow Transplantation.

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:: Invasive aspergillosis (IA) is a common complication in patients with hematologic malignancies. Patients with solid tumors also are at risk for IA because they may develop neutropenia as a result of chemotherapy and radiotherapy. However, studies of IA in patients with solid tumors are rare. In this study,...

journal_title：Cancer

authors： Yan X,Li M,Jiang M,Zou LQ,Luo F,Jiang Y

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Although systemic therapy for metastatic breast cancer (MBC) continues to evolve, there are scant data to guide physicians and patients when symptoms develop. In this article, the authors report the frequency and durability of palliative procedures performed in the setting of MBC. METHODS:From July 2002 to ...

journal_title：Cancer

authors： Morrogh M,Miner TJ,Park A,Jenckes A,Gonen M,Seidman A,Morrow M,Jaques DP,King TA

更新日期：2010-07-15 00:00:00

abstract：BACKGROUND:The development of new chelating agents and radiolabeling protocols is essential to progress in radioimmunotherapy with antibody-chelate conjugates. METHODS:Immunoconjugates of four polyazamacrocycles with N-bonded acetate groups were prepared by conjugation via 2-iminothiolane to Lym-1, a murine antilympho...

journal_title：Cancer

authors： Kukis DL,Diril H,Greiner DP,DeNardo SJ,DeNardo GL,Salako QA,Meares CF

更新日期：1994-02-01 00:00:00

abstract：:Elevated serum levels of carcinoembryonic antigen (CEA) were found in 70% of 141 patients with advanced gastrointestinal (GI) cancers. Serial CEA measurements were performed on 70 patients before and during chemotherapy. The majority were treated with 5-FU and Methyl-CCNU (33 patients), 5-FU (19 patients), or 5-FU and...

journal_title：Cancer

authors： Al-Sarraf M,Baker L,Talley RW,Kithier K,Vaitkevicius VK

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:The authors reviewed changes in the initial clinical presentation, management techniques, and patterns of disease recurrence over time (1981-1996) in patients with breast carcinoma treated with breast-conserving therapy (BCT) at a single institution. The goals of the current study were to determine the frequ...

journal_title：Cancer

authors： Pass H,Vicini FA,Kestin LL,Goldstein NS,Decker D,Pettinga J,Ingold J,Benitez P,Neumann K,Rebner M,Dekhne N,Martinez A

更新日期：2004-08-15 00:00:00

abstract：BACKGROUND:Endocrine therapy resistance is a major cause of distant recurrence (DR) in hormone receptor-positive breast cancer. This study evaluated differences in survival after DR in patients treated with different adjuvant endocrine therapy regimens in the Breast International Group (BIG) 1-98 trial. METHODS:BIG 1-...

journal_title：Cancer

authors： Leone JP,Cole BF,Regan MM,Thürlimann B,Coates AS,Rabaglio M,Giobbie-Hurder A,Gelber RD,Ejlertsen B,Harvey VJ,Neven P,Láng I,Bonnefoi H,Wardley A,Goldhirsch A,Di Leo A,Colleoni M,Vaz-Luis I,Lin NU

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:The authors have noted that in cervical cytology specimens from perimenopausal and postmenopausal women, the diagnosis of atypical squamous cells of undetermined significance (ASC-US), as defined in the Bethesda system, is often not associated with a clinically evident lesion on follow-up. Reflex human papil...

journal_title：Cancer

authors： Johnston EI,Logani S

更新日期：2007-06-25 00:00:00

abstract：BACKGROUND:Helicobacter pylori recently was identified as a risk factor for gastric cancer. Its association with preneoplastic conditions of the stomach, however, is undocumented. METHODS:Gastric biopsy specimens from 245 symptomatic patients were examined for neoplastic and preneoplastic lesions and for gastric H. py...

journal_title：Cancer

authors： Guarner J,Mohar A,Parsonnet J,Halperin D

更新日期：1993-01-15 00:00:00

abstract：:Therapeutic intervention in a course of illness, while producing the desired result, also may have some adverse long-term effects on the patient. Second malignancies are one of the known complications of therapy. The treatments of gynecologic cancers by surgery, irradiation and chemotherapy have been associated with s...

journal_title：Cancer

authors： Messerschmidt GL,Hoover R,Young RC

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:Stereotactic radiation therapy is highly effective in the treatment of small brain metastases, regardless of the histology. This suggests that small extracranial malignancies may be curable with similar radiation therapy. The authors developed a novel treatment unit for administering such therapy. METHODS:T...

journal_title：Cancer

authors： Uematsu M,Shioda A,Tahara K,Fukui T,Yamamoto F,Tsumatori G,Ozeki Y,Aoki T,Watanabe M,Kusano S

更新日期：1998-03-15 00:00:00

abstract：:The relationships between cigarette smoking, occupational exposures, dietary vitamin A and lung cancer is explored in a case-control study. The study is based on 1002 primary lung cancers among white men and 1119 white male controls between 35 and 79 years of age admitted to Roswell Park Memorial Institute from 1957 t...

journal_title：Cancer

authors： Vena JE,Byers TE,Cookfair D,Swanson M

更新日期：1985-08-15 00:00:00