Gynecologic cancer treatment: risk factors for therapeutically induced neoplasia.

abstract：:Pain management often is difficult in patients with bone metastases. Metastatic disease represents >40% of oncologic practice, and >70% of patients with metastatic disease have uncontrolled cancer-related pain. Significant morbidity caused by pathologic fracture and spinal cord compression can result from untreated bo...

journal_title：Cancer

authors： Janjan NA

更新日期：1997-10-15 00:00:00

abstract：BACKGROUND:The majority of patients with astrocytomas of the cerebellum have an excellent prognosis; however, a small percentage of patients continue to do poorly. To clarify the clinical, pathologic, and treatment characteristics that determine prognosis and therapeutic recommendations, a large group of patients with ...

journal_title：Cancer

authors： Hayostek CJ,Shaw EG,Scheithauer B,O'Fallon JR,Weiland TL,Schomberg PJ,Kelly PJ,Hu TC

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Irinotecan-based chemotherapy regimens are 1 option for treatment of metastatic colorectal cancer (mCRC). The authors report the safety and efficacy of such regimens in elderly patients using a large phase III trial (bolus, infusional, or capecitabine with camptostar-celecoxib [BICC-C]) cohort. METHODS:In p...

journal_title：Cancer

authors： Jackson NA,Barrueco J,Soufi-Mahjoubi R,Marshall J,Mitchell E,Zhang X,Meyerhardt J

更新日期：2009-06-15 00:00:00

abstract：BACKGROUND:The Female Sexual Function Index (FSFI) is the most commonly used self-report instrument to measure sexual functioning among women cancer survivors. Despite this, the validity and reliability of the FSFI for use in cancer populations has not been established. METHODS:Data were combined from 3 separate insti...

journal_title：Cancer

authors： Baser RE,Li Y,Carter J

更新日期：2012-09-15 00:00:00

abstract：:In a 3 1/2 year cytogenetic study of 107 leukemia patients diagnosed in childhood and adloescence, 8 presented with chronic myelogenous leukemia (CML). Seven of the 8 had chromosomal abnormalities. Six had the Ph1 chromosome; 5 had the usual 9;22 translocation. Two patients had involvement with chromosome 15; one had ...

journal_title：Cancer

authors： Hays T,Morse H,Peakman D,Rose B,Robinson A

更新日期：1979-07-01 00:00:00

abstract：:The diagnosis of pulmonary candidiasis can only be made with certainty when tissue invasion by the organism is demonstrated histologically. In order to ascertain whether characteristic radiographic patterns are seen in patients with pulmonary candidiasis, antemortem radiographic abnormalities were correlated with auto...

journal_title：Cancer

authors： Dubois PJ,Myerowitz RL,Allen CM

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:To evaluate the hearing preservation rate and to determine its prognostic factors after gamma knife (GK) stereotactic radiosurgery (SRS) in patients with vestibular schwannoma, the authors used a prospective study design to analyze these patients. METHODS:Between December 1997 and January 2002, 25 patients ...

journal_title：Cancer

authors： Paek SH,Chung HT,Jeong SS,Park CK,Kim CY,Kim JE,Kim DG,Jung HW

更新日期：2005-08-01 00:00:00

abstract：:This study examined public attitudes toward pain associated with cancer and its treatment. A variety of issues were assessed, including the extent to which pain is associated with cancer, fear of pain as a factor in the decision to delay seeking treatment, and concerns about the use of narcotic analgesics for pain con...

journal_title：Cancer

authors： Levin DN,Cleeland CS,Dar R

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Axillary dissection in elderly patients with early-stage breast carcinoma who do not have palpable axillary lymph nodes is controversial because of the associated morbidity of the surgery, reduced life expectancy of the patients, and efficacy of hormone therapy in preventing recurrences and axillary events. ...

journal_title：Cancer

authors： Martelli G,Miceli R,De Palo G,Coradini D,Salvadori B,Zucali R,Galante E,Marubini E

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Radiotherapy (RT) after breast-conserving surgery (BCS) has produced significant reductions in ipsilateral breast carcinoma (BC) recurrence. It was shown previously that a delay in the initiation of RT resulted in a higher local recurrence (LR) rate. In the current retrospective analysis, the authors investi...

journal_title：Cancer

authors： Benchalal M,Le Prisé E,de Lafontan B,Berton-Rigaud D,Belkacemi Y,Romestaing P,Peignaux K,Courdi A,Monnier A,Montcuquet P,Goudier MJ,Marchal C,Chollet P,Abadie-Lacourtoisie S,Datchary J,Veyret C,Kerbrat P

更新日期：2005-07-15 00:00:00

abstract：BACKGROUND:Prevalence usually is defined as the proportion of individuals alive who previously had a diagnosis of the disease, regardless of whether the individuals still are receiving treatment or are cured. The objective of this study was to estimate the proportion of elderly patients with colorectal carcinoma (CRC) ...

journal_title：Cancer

authors： Mariotto A,Warren JL,Knopf KB,Feuer EJ

更新日期：2003-09-15 00:00:00

abstract：:The initial response and long-term follow-up of 74 evaluable patients who received combination chemotherapy for metastatic nonseminomatous testicular cancer are reported. Patients were treated with a protocol (VAB-3) including vinblastine, actinomycin-D, bleomycin, and cis-dichlorodiammine platinum (DDP). VAB-3 alone ...

journal_title：Cancer

authors： Reynolds TF,Vugrin D,Cvitkovic E,Cheng E,Braun DW Jr,O'Hehir MA,Dukeman ME,Whitmore WF Jr,Golbey RB

更新日期：1981-08-15 00:00:00

abstract：:Two hundred and forty patients, asymptomatic relative to gastrointestinal disease, who applied for elective hernia repair, were tested as outpatients for occult blood in the stool. Thirty-eight patients had one or more positive specimens. Significant pathologic characteristics were identified by lower gastrointestinal...

journal_title：Cancer

authors： Morris DM,Daron PB,Goldman LI

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:The purpose of this study is to examine changes over time in survival for African American (AA) and white women diagnosed with cervical cancer (CC). METHODS:Surveillance, Epidemiology, and End Results (SEER) Program data from 1985 to 2009 were used for this analysis. Racial differences in survival were eval...

journal_title：Cancer

authors： Rauh-Hain JA,Clemmer JT,Bradford LS,Clark RM,Growdon WB,Goodman A,Boruta DM 2nd,Schorge JO,del Carmen MG

更新日期：2013-10-15 00:00:00

abstract：:Transgenic model systems provide tools for obtaining information that clarifies important relationships between genetic alterations and carcinogenesis. One such relationship is the induction of specific growth factor activities by dominantly acting oncogenes. Using a "transgenic organ" model referred to as mouse prost...

journal_title：Cancer

authors： Thompson TC,Truong LD,Timme TL,Kadmon D,McCune BK,Flanders KC,Scardino PT,Park SH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Squamous cell carcinoma of the esophagus is endemic in parts of South Africa. Previous case-control studies have shown many associations but no clear etiologic pathway has been established. METHODS:A case-control study of dietary and social factors was performed for 130 patient/control pairs matched for age...

journal_title：Cancer

authors： Sammon AM

更新日期：1998-08-01 00:00:00

abstract：:Plasma TSH and thyroxine levels were measured in 74 early breast cancer patients and 53 with advanced disease, 77 patients with cancer arising in other organs and 67 healthy women of similar age. The mean plasma TSH levels were higher in the breast cancer cases than the other two groups; the difference was statistical...

journal_title：Cancer

authors： Rose DP,Davis TE

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Cancer of the male breast (MBC) is rare, accounting for less than 1% of cancer in males and representing less than 1% of all breast cancers. Reports of abnormalities in the expression of the tumor suppressor gene p53 in MBC have been few. METHODS:To assess the expression and mutations of the p53 gene, 35 pa...

journal_title：Cancer

authors： Anelli A,Anelli TF,Youngson B,Rosen PP,Borgen PI

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Carcinoid tumors are unusual and most reports are anecdotal or limited in number. A series of 2837 cases was published in 1975. No recent large series is available. METHODS:The authors evaluated 5468 cases identified by the Surveillance, Epidemiology, and End Results (SEER) program of the National Cancer In...

journal_title：Cancer

authors： Modlin IM,Sandor A

更新日期：1997-02-15 00:00:00

abstract：BACKGROUND:Hypoxia inducible factor-1 (HIF-1) plays a critical role in angiogenesis during vascular development. The authors tested the hypothesis that HIF-1 expression correlates with progression and angiogenesis in brain tumors. METHODS:The authors investigated the expression of the HIF-1alpha and HIF-1beta subunits...

journal_title：Cancer

authors： Zagzag D,Zhong H,Scalzitti JM,Laughner E,Simons JW,Semenza GL

更新日期：2000-06-01 00:00:00

abstract：:The 4F2 antigen is a cell-membrane glycoprotein which arises early in the G0-G1 phases of the cell cycle. This molecule is present in all established human cell lines and most malignant human cells. The authors used an indirect immunophosphatase method to study 50 squamous cell carcinomas of the larynx and ten lymph-n...

journal_title：Cancer

authors： Esteban F,Ruiz-Cabello F,Concha A,Perez Ayala M,Delgado M,Garrido F

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Assessment of prognostic markers in breast cancer independent of the axillary lymph node status is of major concern for the application of adjuvant treatment regimens. The current treatment decision is based mainly on the axillary lymph node status. Because of improved screening methods, the number and propo...

journal_title：Cancer

authors： Friedrichs K,Gluba S,Eidtmann H,Jonat W

更新日期：1993-12-15 00:00:00

abstract：BACKGROUND:Advanced non-Hodgkin lymphoma (NHL) usually is treated with doxorubicin-based combination chemotherapy. Because doxorubicin is excreted by the biliary route, many authorities recommend alternative initial interventions in patients with NHL causing obstructive jaundice. METHODS:The authors retrospectively re...

journal_title：Cancer

authors： Dudgeon DJ,Brower M

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:In regional lymph node metastasis of cutaneous melanoma, the number and volume of involved lymph nodes are the most important prognostic factors. Several studies have revealed that palpation of the lymphatic drainage area(s) and regional lymph nodes has a high rate of false-negative results during follow-up....

journal_title：Cancer

authors： Blum A,Schlagenhauff B,Stroebel W,Breuninger H,Rassner G,Garbe C

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The local control rates of T1 and T2 supraglottic carcinoma treated with radiation alone were reported as 71% to 92% and 59% to 83%, respectively. The factors that affect the local control rate for early supraglottic carcinoma were investigated. METHODS:From 1967 through 1985, 100 cases with early supraglot...

journal_title：Cancer

authors： Inoue T,Matayoshi Y,Inoue T,Ikeda H,Teshima T,Murayama S

更新日期：1993-07-01 00:00:00

abstract：:This study investigated whether an endoscopic surveillance program for patients with "benign" gastric ulcers and gastric cancer leads to early detection of neoplasms and improves survival. The clinical course of all patients diagnosed between 1977 and 1986 as having either gastric ulcers or gastric cancer was followed...

journal_title：Cancer

authors： Eckardt VF,Giessler W,Kanzler G,Bernhard G

更新日期：1992-01-15 00:00:00

abstract：BACKGROUND:Several investigators have reported the ability to establish xenografts in nude mice from children with neuroblastomas, but a correlation of prognosis with this establishment and the growth patterns of the neuroblastomas has not been reported. METHODS:Tumor specimens from 58 children with neuroblastomas wer...

journal_title：Cancer

authors： George BA,Yanik G,Wells RJ,Martin LW,Soukup S,Ballard ET,Gartside PS,Lampkin BC

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The treatment of metastatic renal cell carcinoma (RCC) with high-dose interleukin-2 (HD IL-2) has resulted in durable tumor regression in a minority of patients. The current study presents the authors' 20-year experience administering this immunotherapeutic agent. METHODS:Patients with metastatic RCC (n = 2...

journal_title：Cancer

authors： Klapper JA,Downey SG,Smith FO,Yang JC,Hughes MS,Kammula US,Sherry RM,Royal RE,Steinberg SM,Rosenberg S

更新日期：2008-07-15 00:00:00

abstract：:Pericardial effusion and trifascicular block developed 5 years following mediastinal irradiation for Hodgkin's disease in a 19-year-old patient. Another 24-year-old patients had an acute myocardial infarction followed by severe angina pectoris 5 years following mediastinal irradiation for the same disease. A pericardi...

journal_title：Cancer

authors： Ali MK,Kahlil KG,Fuller LM,Leachman RD,Sullivan MP,Loh KK,Gamble JF,Shullenberger CC

更新日期：1976-11-01 00:00:00

abstract：:In 79 cases of histologically verified anaplastic giant-cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy-eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an add...

journal_title：Cancer

authors： Jereb B,Stjernswärd J,Löwhagen T

更新日期：1975-05-01 00:00:00