Plasma thyroid-stimulating hormone and thyroxine concentrations in breast cancer.

Abstract:

:Plasma TSH and thyroxine levels were measured in 74 early breast cancer patients and 53 with advanced disease, 77 patients with cancer arising in other organs and 67 healthy women of similar age. The mean plasma TSH levels were higher in the breast cancer cases than the other two groups; the difference was statistically significant only in those with advanced disease. Twelve percent of the early breast cancer and 15% of the advanced breast cancer patients had elevated plasma TSH concentrations, compared with only 1% of the other cancer patients and 3% of the controls. Four breast cancer patients with plasma TSH levels above 85 microIU/ml had subnormal plasma thyroxine levels. Five of 29 (17%) early breast cancer patients had excessive plasma TSH responses to TRH.

journal_name

Cancer

journal_title

Cancer

authors

Rose DP,Davis TE

doi

10.1002/1097-0142(197802)41:2<666::aid-cncr2820410

subject

Has Abstract

pub_date

1978-02-01 00:00:00

pages

666-9

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

41

pub_type

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