Abstract:
:The authors draw on the lessons highlighted in preceding articles in the current supplement to provide recommendations for cancer screening intervention research and to highlight some of the many questions that will require further investigation.
journal_name
Cancerjournal_title
Cancerauthors
Meissner HI,Vernon SW,Rimer BK,Wilson KM,Rakowski W,Briss PA,Smith RAdoi
10.1002/cncr.20510subject
Has Abstractpub_date
2004-09-01 00:00:00pages
1251-9issue
5 Suppleissn
0008-543Xissn
1097-0142journal_volume
101pub_type
杂志文章,评审相关文献
CANCER文献大全abstract::Several reports describe the association of hyperlymphocytosis with neutropenia. This syndrome, named lymphoproliferative disease, is characterized by a chronic indolent clinical course, bone marrow lymphocyte infiltration, and granulopenia of central origin. The proliferating lymphocytes share large granular lymphocy...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910515)67:10<2610::aid-cncr282
更新日期:1991-05-15 00:00:00
abstract:BACKGROUND:Because medulloblastoma (MB) is rare in adults, the few studies on this condition have been retrospective, and the follow-up has tended to be short. Furthermore, the different therapeutic strategies used in these patients has made it difficult to assess survival rates and prognostic factors. METHODS:In 1989...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23003
更新日期:2007-11-01 00:00:00
abstract::The long-term effect of cisplatin on renal function was studied in a follow-up investigation, 16 to 52 months after chemotherapy in 22 patients with disseminated nonseminomatous testicular cancer. The median cumulated cisplatin dose was 452 mg/m2 (range, 275-650 mg/m2). Prehydration with isotonic saline secured diures...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19861115)58:10<2214::aid-cncr282
更新日期:1986-11-15 00:00:00
abstract::Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whether CCNU and/or vinblastine are more effective than mechlorethamine and/or vincristine with procarbazine and prednisone. The combination of CCNU, vinblastine, procarbazine, and prednisone (CVPP) ...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(19800815)46:4<654::aid-cncr28204
更新日期:1980-08-15 00:00:00
abstract::Transcriptional dysregulation induced by disease-defining genetic alterations of proteins in transcriptional machinery is a key feature of cancers. Mediator complex subunit 12 (MED12) is the central architectural subunit in the kinase module of Mediator, a large transcriptional regulatory complex that controls essenti...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.32672
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Adequate prediction of survival is important in deciding on treatment for patients with symptomatic spinal metastases. The authors reviewed 342 patients with painful spinal metastases without neurologic impairment who were treated conservatively within a large, prospectively randomized radiotherapy trial. Re...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/cncr.20756
更新日期:2005-01-15 00:00:00
abstract:BACKGROUND:A single-institution, prospective, randomized open trial was performed to compare ondansetron and granisetron in the prevention of chemotherapy-related nausea and vomiting. The effect of antemetic drugs was analyzed indipendently for patients treated with highly emetogenic chemotherapy (Study 1), and those t...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(19941001)74:7<1945::aid-cncr2820
更新日期:1994-10-01 00:00:00
abstract::Twenty-four children aged 3 months to 18 years (median, 12 years) were treated for neurogenic sarcoma at the Children's Hospital of Philadelphia Cancer Research Center from 1958 through 1984. Sixteen patients had neurofibromatosis (NF). The tumors arose in an extremity or in the trunk (15 patients), the retroperitoneu...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870101)59:1<1::aid-cncr2820590
更新日期:1987-01-01 00:00:00
abstract::Recombinant human granulocyte colony-stimulating factor (rhG-CSF) was administered intraperitoneally in combination with multidrug chemotherapy using methotrexate (M), vinblastine (V), doxorubicin (A), and cisplatin (C, or for the combination, MVAC) to C3H/He mice (5-week-old females) after experimental carcinoma, MBT...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920215)69:4<997::aid-cncr28206
更新日期:1992-02-15 00:00:00
abstract::Flow cytometry (FC) analysis including DNA index (ploidy status) and cell kinetics (%S and %S + G2/M) was done on frozen tissue of the primary lesions of 101 women with node negative (N-) breast cancer who were studied prospectively. Currently, 19% (19/101) of the patients have recurred. No significant relations have ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19891101)64:9<1894::aid-cncr2820
更新日期:1989-11-01 00:00:00
abstract::Congenital self-healing histiocytosis (CSHH) is a rare primary histiocytic skin disorder. Only a few cases have been studied by ultrastructure and immunohistochemistry. Here we report a new case that was investigated using an electron microscope and a panel of monoclonal (MCA) and polyclonal (PCA) antibodies. CSHH cel...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19880201)61:3<508::aid-cncr28206
更新日期:1988-02-01 00:00:00
abstract::Breast cancer is one of the most responsive of the common solid tumors when systemic therapy is indicated in the treatment of locally advanced or disseminated cancer. Many single agents have been useful in inducing remission in mammary carcinoma, but in recent years various drug combinations have been developed that a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800815)46:4+<1079::aid-cncr282
更新日期:1980-08-15 00:00:00
abstract:BACKGROUND:An epidermal growth factor receptor (EGFR) immunohistochemical detection system currently is being developed. The current study attempts to address background EGFR reactivity issues before determining the optimum EGFR scoring system. METHODS:Tissue sections from 102 patients with T3N1-2M1 colon adenocarcino...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010901)92:5<1331::aid-cncr1455
更新日期:2001-09-01 00:00:00
abstract::Serum ferritin levels were monitored in nine patients with acute lymphoblastic leukemia (ALL), nine patients with acute nonlymphoblastic leukemia (ANLL), four patients with chronic myelogenous leukemia (CML), three patients with non-Hodgkin's lymphoma (NHL), and three patients with severe aplastic anemia (SAA) undergo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870901)60:5<1127::aid-cncr2820
更新日期:1987-09-01 00:00:00
abstract::Many cancer patients have elevated serum protein and sialic acid (N-acetyl neuraminic acid, NANA) levels. Serial determinations were performed, using serum treated with perchloric acid from 34 patients with widespread metastatic disease. Six of six patients who underwent debulking surgery had a drop in their serum NAN...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810115)47:2<324::aid-cncr28204
更新日期:1981-01-15 00:00:00
abstract::The clinical findings in 262 patients with melanoma were correlated with an assessment of their cellular-mediated immunity by delayed-type hypersensitivity (DTH) skin tests, by lymphocyte blastogenesis, and by leukocyte enumerations. Patients with systemic metastases (stage IV) and those with evidence of tumor burden ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197806)41:6<2165::aid-cncr282041
更新日期:1978-06-01 00:00:00
abstract::A 78-year-old Japanese man with chronic liver disease developed hypervascular liver tumors accompanied by marked elevation of alphafetoprotein value (the highest level; 26200 ng/ml) and pathologic fracture of the femur. After an operation for the fracture followed by gastrointestinal bleeding and repeated transfusions...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850801)56:3<667::aid-cncr28205
更新日期:1985-08-01 00:00:00
abstract::During 6375 patient-years of observation, 136 new cancers developed in 117 of 1429 patients with squamous cell carcinoma of the oral cavity. The risk of multiple cancers was excessive in the upper digestive or respiratory tract in patients with squamous cell carcinoma of the oral cavity, accounting for 87 (64%) of the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19871215)60:12<3083::aid-cncr282
更新日期:1987-12-15 00:00:00
abstract:BACKGROUND:Vitiligo is a dermatologic disease characterized by local, dispersed, or diffuse white patches on the skin. The disease is defined as an autoimmune disorder because autoantibodies against membranal components of melanocytes are found in the patients' sera. The current study examined whether the autoantibodie...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931015)72:8<2365::aid-cncr2820
更新日期:1993-10-15 00:00:00
abstract::A randomized study was designed to determine the effect of intermittent oral cyclophosphamide on the rate of metastases in children with localized and regional neuroblastoma. Secondary objectives of the study were to determine the value of the proposed staging system, to measure the influence of the peripheral lymphoc...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(197608)38:2<661::aid-cncr2820380
更新日期:1976-08-01 00:00:00
abstract::Selective adsorption of several common "monospecific" HLA typing sera with HLA typed platelets, purified B lymphocytes, cultured lymphoid cells, or lymphocytes from patients with active chronic lymphocytic leukemia demonstrated that many of these sera contain antibodies to non-HLA antigens. Antibodies were detected to...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197706)39:6<2348::aid-cncr282039
更新日期:1977-06-01 00:00:00
abstract:BACKGROUND:Conflicting results have been obtained regarding blood flow distribution to liver tumors. The emphasis on portal vein perfusion has had a great impact on the design of treatment protocols. METHODS:Double microsphere technique with reference organ sampling was used for the measurement of hepatic artery and p...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19941101)74:9<2454::aid-cncr2820
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Previous Commission on Cancer studies have examined time trends in stage of disease, treatment patterns, and survival for special populations. Reported herein are the most current National Cancer Data Base data for Hispanics. METHODS:Two Calls for Data have yielded a total of 23,650 cancer reports for Hispa...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19941015)74:8<2386::aid-cncr2820
更新日期:1994-10-15 00:00:00
abstract::The frequency and significance of hyperprolactinemia was studied in 21 consecutive, untreated male patients with bronchogenic carcinoma. Seven patients (33%) were found to have elevated serum prolactin (hPRL) levels. No correlation was demonstrated between increased hPRL levels, tissue histology, or tumor burden. L-do...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197908)44:2<676::aid-cncr2820440
更新日期:1979-08-01 00:00:00
abstract::One hundred eighty-four patients with advanced measurable colorectal cancer not previously treated with chemotherapy were entered into a prospective randomized clinical trial by the Mid-Atlantic Oncology Program (MAOP) to assess the value of weekly cisplatin (20 mg/m2) when added to a protracted schedule of 5-fluorour...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/1097-0142(19910101)67:1<14::aid-cncr282067
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Lung carcinoma usually is advanced at the time of presentation and frequently shows metastatic spread. In recent times, prognostic factors such as c-erbB-2 in patients with breast carcinoma have provided useful information and beneficial therapeutic targets. The objective of this study was to evaluate angiog...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20011115)92:10<2648::aid-cncr161
更新日期:2001-11-15 00:00:00
abstract:BACKGROUND:The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene resulting from the chromosome inversion inv(2)(p21;p23) recently was identified in nonsmall cell lung cancer (NSCLC). The authors of this study investigated the frequency, genetic and clinicopathologic prof...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24181
更新日期:2009-04-15 00:00:00
abstract::A series of eight plasma cell granulomas of the lung were examined. Their clinical, pathologic, and immunohistochemical characteristics as well as the ultrastructural features of one case are in agreement with those found in the literature. One patient died after a surgical intervention complicated by invasion of pulm...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870201)59:3<435::aid-cncr28205
更新日期:1987-02-01 00:00:00
abstract::Carcinoembryonic antigen is only a tumor assoicated antigen and is less clinically useful than the original report suggested. However, the CEA assays in clinical use utilize reagents operationally defined by old criteria. There is now abundant evidence that "CEA" consists of a heterogenous family of related glycoprote...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197809)42:3+<1585::aid-cncr28204
更新日期:1978-09-01 00:00:00
abstract:BACKGROUND:Most patients with cutaneous squamous cell carcinoma (cSCC) of the head and neck (HN) are at low-risk (<5%) of developing metastatic SCC to regional lymph nodes. However, patients with unfavorable clinicopathologic factors often are under appreciated by clinicians but remain at higher risk for developing met...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21898
更新日期:2006-06-01 00:00:00