Abstract:
:Selective adsorption of several common "monospecific" HLA typing sera with HLA typed platelets, purified B lymphocytes, cultured lymphoid cells, or lymphocytes from patients with active chronic lymphocytic leukemia demonstrated that many of these sera contain antibodies to non-HLA antigens. Antibodies were detected to antigens present on peripheral blood B-lymphocytes, cultured lymphoid cells and leukemic cells from patients with both myelocytic and lymphocytic forms of leukemia but absent from T-lymphocytes and platelets. Since these kinds of antibodies appear to be present in a large proportion of common HLA typing sera, caution should be used in interpreting all data related to HLA antigen expression in leukemia.
journal_name
Cancerjournal_title
Cancerauthors
Pollack MS,DuBois Ddoi
10.1002/1097-0142(197706)39:6<2348::aid-cncr282039subject
Has Abstractpub_date
1977-06-01 00:00:00pages
2348-54issue
6eissn
0008-543Xissn
1097-0142journal_volume
39pub_type
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