Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer.

abstract：:The present study was carried out to investigate a distinctive type of carcinoma of the uterine cervix categorized under the designation as circumscribed carcinoma with lymphocytic infiltration. Grossly this carcinoma is characterized by defined circumscription with a superficial ulceration. A microscropic feature cha...

journal_title：Cancer

authors： Hasumi K,Sugano H,Sakamoto G,Masubuchi K,Kubo H

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:A survey of the distribution of human papillomavirus (HPV) types across the spectrum of cervical cytologic categories defined by the Bethesda 2001 guidelines was conducted with the objective of examining how HPV detection by polymerase chain reaction (PCR) analysis may benefit the management of patients who ...

journal_title：Cancer

authors： Evans MF,Adamson CS,Papillo JL,St John TL,Leiman G,Cooper K

更新日期：2006-03-01 00:00:00

abstract：:The issue of how immunoglobulins are transported across the intestinal epithelium into the gut lumen was examined by immunohistocytochemical techniques. IgA, IgM, IgG and secretory component (SC) in human small intestine at light and electron microscopic levels were localized by the peroxidase-labeled antibody techniq...

journal_title：Cancer

authors： Brown WR

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Intraabdominal desmoplastic small cell tumor is a rare malignancy that has only recently been described. In the adult population, it is usually seen in young males. The tumor appears to arise as a dominant mass or masses in the abdominal cavity, particularly in the pelvic region, without a clear visceral ori...

journal_title：Cancer

authors： Amato RJ,Ellerhorst JA,Ayala AG

更新日期：1996-08-15 00:00:00

abstract：BACKGROUND:To evaluate the prevalence and significance of abnormal ovarian findings in asymptomatic postmenopausal women, screening for ovarian cancer with color Doppler ultrasound was performed. METHODS:One thousand three hundred sixty-four asymptomatic women aged 56-61 years (mean, 59 years) were examined by color D...

journal_title：Cancer

authors： Vuento MH,Pirhonen JP,Mäkinen JI,Laippala PJ,Grönroos M,Salmi TA

更新日期：1995-10-01 00:00:00

abstract：:Disagreement persists about the superiority of Reagan and Ng's method over that of Broders' for the histologic grading of squamous carcinoma of the cervix. Uncertainty about the predictive value and reproducibility of any of the grading methods prompted a comparison of factors previously suggested as indicating the bi...

journal_title：Cancer

authors： Zaino RJ,Ward S,Delgado G,Bundy B,Gore H,Fetter G,Ganjei P,Frauenhoffer E

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Acquired Glanzmann's thrombasthenia is a rare hemorrhagic diathesis resulting from impaired adhesive function of the platelet receptor GPIIb/IIIa (alpha(IIb)beta3). Typically, this disorder develops during adulthood, with patients manifesting fluctuating clinical and laboratory findings. To date, the underly...

journal_title：Cancer

authors： Malik U,Dutcher JP,Oleksowicz L

更新日期：1998-05-01 00:00:00

abstract：:In a cohort of 254,417 male Swedish farmers (4,330,717 person-years) the incidence of cancer of the respiratory organs was compared to a reference cohort of 1,725,845 men (30,131,664 person-years) employed in other economic activities than agriculture or forestry. In the study cohort 1450 cases of cancer in the respir...

journal_title：Cancer

authors： Wiklund K,Steineck G

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:The diagnosis of melanomas at an early stage is associated with improved survival, so the recognition of changes in pigmented skin lesions over time is important. We have developed a computer imaging system with the aim of assisting clinicians in differentiating early melanomas from benign pigmented skin les...

journal_title：Cancer

authors： Aitken JF,Pfitzner J,Battistutta D,O'Rourke PK,Green AC,Martin NG

更新日期：1996-07-15 00:00:00

abstract：BACKGROUND:The authors previously demonstrated that never-smokers with stage IIIB/IV nonsmall cell lung cancer (NSCLC) lived 50% longer than former/current smokers. This observation persisted after adjusting for age, performance status, and sex. In this study, the authors hypothesized that smoking-dependent differences...

journal_title：Cancer

authors： Paik PK,Johnson ML,D'Angelo SP,Sima CS,Ang D,Dogan S,Miller VA,Ladanyi M,Kris MG,Riely GJ

更新日期：2012-12-01 00:00:00

abstract：:One hundred eighty-three patients with malignant skeletal (83) or soft tissue sarcoma (100) were entered into the multimodality preoperative limb salvage protocol. Local recurrences were observed in 5 of 183 (2.7%). Six patients required amputation because of complications, and 13 patients died within 1 year from meta...

journal_title：Cancer

authors： Eilber FR,Morton DL,Eckardt J,Grant T,Weisenburger T

更新日期：1984-06-15 00:00:00

abstract：:Between August 1978 and November 1981, 33 boys with acute lymphocytic leukemia (ALL) (26 non-T, 7 T-cell) younger than 16 years underwent bilateral wedge testicular biopsies at the time of initial diagnosis. Seven (4 non-T, 3 T-cell) demonstrated focal leukemic infiltrates. Rebiopsy after successful induction therapy ...

journal_title：Cancer

authors： Kim TH,Hargreaves HK,Chan WC,Brynes RK,Alvarado C,Woodard J,Ragab AH

更新日期：1986-03-01 00:00:00

abstract：:To assess the efficacy of performing both computed tomography (CT) of the thorax and upper abdomen and whole-body gallium scintigraphy for staging lung cancer, the results of each test were compared with those obtained by chest radiography and clinical examination in 100 patients. Clinical efficacy was defined in term...

journal_title：Cancer

authors： MacMahon H,Scott W,Ryan JW,Montner SM,Little AG,Hoffman PC,Ferguson MK,Golomb HM

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:ThinPrep liquid-based cytology (TP) preparations are being used increasingly in nongynecologic specimens. To the authors' knowledge, few studies to date have evaluated TP cytology in the setting of small cell carcinoma of the lung (SCCL). Accurately differentiating SCCL from other lung tumors has important c...

journal_title：Cancer

authors： Kim S,Owens CL

更新日期：2009-02-25 00:00:00

abstract：BACKGROUND:The authors compared the survival outcomes of radiotherapy+/-salvage surgery to surgery+/-postoperative radiotherapy for patients with squamous cell cancer of the hypopharynx. There was no evidence beyond observational studies and no consensus on the which treatment is most effective for this patient group. ...

journal_title：Cancer

authors： Hall SF,Groome PA,Irish J,O'Sullivan B

更新日期：2009-12-15 00:00:00

abstract：:To investigate histologic prognostic factors in soft tissue sarcomas (STS), multivariate analysis was performed on 236 patients with complete clinical information. These included 141 males and 95 females with an age range from 1 to 85 years (median, 47.6 years). Histologically, malignant fibrous histiocytoma (33.5%) w...

journal_title：Cancer

authors： Tsujimoto M,Aozasa K,Ueda T,Morimura Y,Komatsubara Y,Doi T

更新日期：1988-09-01 00:00:00

abstract：:Forty-eight cases of primary insular carcinoid of the ovary were analyzed from a clinicopathologic viewpoint. Sixteen (33%) were associated with preoperative clinical evidence of the carcinoid syndrome. At operation only one ovary was usually enlarged, but in 16% the contralateral ovary was also enlarged by either a d...

journal_title：Cancer

authors： Robboy SJ,Norris HJ,Scully RE

更新日期：1975-08-01 00:00:00

abstract：:The livers of 345 autopsy cases of chronic liver disease were examined for macroregenerative nodule (MRN), a large nodular lesion more than 10 mm in diameter. A total of 86 lesions of MRN was found in 49 cases (14.2%): 32 were from 191 cases of hepatocellular carcinoma (HCC), 16 were from 148 cases of cirrhosis only, ...

journal_title：Cancer

authors： Furuya K,Nakamura M,Yamamoto Y,Togei K,Otsuka H

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:A previous study found that medroxyprogesterone acetate (MPA) delayed the in vivo growth of three (AsPC-1, Capan-2, and MiaPaCa-2) of nine human pancreatic carcinoma cell lines transplanted into nude mice (Cancer 1995; 75:1263-72). The current study was undertaken to evaluate the basis for this inhibitor. M...

journal_title：Cancer

authors： Abe M,Yamashita J,Ogawa M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase 2 (COX-2)-dependent signaling represents a potential mechanism of resistance to therapy with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. This is mediated in part through an EGFR-independent activation of mitogen-activated protein kinase (MAPK)/extracellular signal-regul...

journal_title：Cancer

authors： Reckamp KL,Koczywas M,Cristea MC,Dowell JE,Wang HJ,Gardner BK,Milne GL,Figlin RA,Fishbein MC,Elashoff RM,Dubinett SM

更新日期：2015-09-15 00:00:00

abstract：:A patient developed widely metastatic adenoid cystic carcinoma of the parotid gland after several local recurrences. A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C. This is the second complete response ...

journal_title：Cancer

authors： Budd GT,Groppe CW

更新日期：1983-02-15 00:00:00

abstract：BACKGROUND:The influence of various clinicopathologic features on survival of patients with papillary thyroid carcinoma has been examined. In particular, histologic grade, which was obtained by a combined assessment of nuclear atypia, tumor necrosis, and vascular invasion (VAN score) was studied. According to this, his...

journal_title：Cancer

authors： Akslen LA

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Thyroid tumorigenesis is characterized by a progressive loss of differentiation exhibited by a range of disease variants. The Notch receptor family (1-4) regulates developmental progression in both normal and cancerous tissues. This study sought to characterize the third Notch isoform (Notch3) across the var...

journal_title：Cancer

authors： Somnay YR,Yu XM,Lloyd RV,Leverson G,Aburjania Z,Jang S,Jaskula-Sztul R,Chen H

更新日期：2017-03-01 00:00:00

abstract：:The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

journal_title：Cancer

authors： Anderström C,Johansson SL,von Schultz L

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:The increasing incidence of human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) highlights the need for simple and effective tools to evaluate head and neck lesions and their HPV status. The main objective of the current study was to investigate the association between abnormal c...

journal_title：Cancer

authors： Donà MG,Giuliani M,Vocaturo A,Spriano G,Pichi B,Rollo F,Ronchetti L,Covello R,Pescarmona E,Benevolo M

更新日期：2014-11-15 00:00:00

abstract：BACKGROUND:Response rates in chronic myeloid leukemia (CML) are now reported based on the cumulative incidence of a single-time best response. The study aim was to examine the significance of different response criteria for CML on imatinib therapy. METHODS:In all, 276 patients with chronic phase CML on imatinib therap...

journal_title：Cancer

authors： Kantarjian H,O'Brien S,Shan J,Huang X,Garcia-Manero G,Faderl S,Ravandi-Kashani F,Verstovsek S,Beth Rios M,Cortes J

更新日期：2008-02-15 00:00:00

abstract：:The introduction of trimodal combination therapy (surgery + radiation + intraarterial infusion) for maxillary carcinoma resulted in a change in the sites of recurrence and no satisfactory improvement in the local control rate. To examine the cause of these phenomena, external carotid angiography was performed on 51 pa...

journal_title：Cancer

authors： Shibuya H,Suzuki S,Horiuchi J,Takagi M,Okuyama T,Suzuki H,Takeda M

更新日期：1982-12-15 00:00:00

abstract：:From November 1985 to August 1988, the National Study Group for Oesophageal Cancer collected and centralized data on 1926 new cases of oesophageal cancer in South Africa. A standard data sheet was used to record the age, sex, and condition of the patients, the site, length, and circumferential extent of the tumor, the...

journal_title：Cancer

authors： Mannell A,Murray W

更新日期：1989-12-15 00:00:00

abstract：BACKGROUND:Lysosomal proteases are implicated in cancer progression and metastasis. In the current study, using subtraction cloning for genes that are differentially expressed in metastasis, the authors isolated a clone encoding ceroid lipofuscinosis, neuronal 2 (CLN2), which is a lysosomal serine protease defective in...

journal_title：Cancer

authors： Tsukamoto T,Iida J,Dobashi Y,Furukawa T,Konishi F

更新日期：2006-04-01 00:00:00

abstract：:A study of primary epithelial neoplasms of the appendix (with the exception of classical carcinoids), produced 24 adenocarcinomas and 42 benign lesions from the files of the Laboratory of Surgical Pathology of Columbia University. Invasive adenoarcinomas were often complicated by appendicitis and were then unexpectedl...

journal_title：Cancer

authors： Wolff M,Ahmed N

更新日期：1976-05-01 00:00:00