Abstract:
:In order to investigate the relationship between histologic findings and clinical behavior in angioimmunoblastic lymphadenopathy (AILD), 44 patients with AILD were reviewed. These patients comprised 24 men and 20 women with age range from 25 to 84 years of age (median, 64 years). Lymphadenopathy was observed in all patients, systemic in 37, and localized in seven. Polyclonal hypergammaglobulinemia was present in 64% of patients. Histologically clear cells or convoluted cells were observed in 36% and 48% of the patients, respectively. Univariate analysis (log-rank test) for prognostic factors revealed age, appetite, presence of clear cells, or convoluted cells were important factors. However, multivariate analysis revealed that there were no independent factors for prognosis. The presence of clear cells and/or convoluted cells were histologic signs for poor prognosis; autopsy showed that patients with the clear cells with or without convoluted cells mostly died of active disease of AILD with two cases progressing to non-Hodgkin's lymphomas and those with convoluted cells alone died of lung infection. From these findings, AILD could be divided into three groups: AILD with (1) clear cells with or without convoluted cells, (2) convoluted cells alone, or (3) neither cells. The first two groups showed poor prognosis, and the last a favorable prognosis.
journal_name
Cancerjournal_title
Cancerauthors
Aozasa K,Ohsawa M,Fujita MQ,Kanayama Y,Tominaga N,Yonezawa T,Matsubuchi T,Hirata M,Uda H,Kanamaru Adoi
10.1002/1097-0142(19890415)63:8<1625::aid-cncr2820subject
Has Abstract,Author List Incompletepub_date
1989-04-15 00:00:00pages
1625-9issue
8eissn
0008-543Xissn
1097-0142journal_volume
63pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Oral mucositis (OM) is a frequent complication of mucotoxic cancer therapy, causing significant oral pain, increased infection risk, and impaired functioning. The efficacy and safety of Saforis (glutamine) powder in UpTec for oral suspension was evaluated for the prevention and treatment of OM. METHODS:Thre...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.22384
更新日期:2007-01-15 00:00:00
abstract::Between August 1978 and November 1981, 33 boys with acute lymphocytic leukemia (ALL) (26 non-T, 7 T-cell) younger than 16 years underwent bilateral wedge testicular biopsies at the time of initial diagnosis. Seven (4 non-T, 3 T-cell) demonstrated focal leukemic infiltrates. Rebiopsy after successful induction therapy ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860301)57:5<1038::aid-cncr2820
更新日期:1986-03-01 00:00:00
abstract:BACKGROUND:The widespread use of anthracycline chemotherapy has contributed to improved outcomes in children with cancer. The most feared complication of the anthracyclines is cardiotoxicity. Routine echocardiographic monitoring typically is used before, during, and after treatment to minimize cardiotoxicity. The ideal...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26481
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:To the authors' knowledge, there is no standard treatment for patients with T-cell large granular lymphocyte (LGL) leukemia. Available data are limited by patient numbers and coexisting pathologies. METHODS:The authors report on the use of immunosuppressants (cyclosporin A [CSA] and low-dose oral methotrexa...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.22032
更新日期:2006-08-01 00:00:00
abstract::Nine patients from 34 to 74 years of age (median, 67 years of age) with uterine papillary serous carcinoma (UPSC) were treated with whole-abdominal radiation therapy (WART) on an adjuvant basis after cytoreductive surgery. All patients were treated with megavoltage photons to an abdominopelvic field to a median dose o...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19911001)68:7<1516::aid-cncr2820
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:Resistance to apoptosis is 1 of the key events that confer chemoresistance and is mediated by the overexpression of antiapoptotic proteins, which inhibit caspase activation. The objective of this study was to evaluate whether the activation of an alternative, caspase-independent cell death pathway could prom...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24397
更新日期:2009-07-15 00:00:00
abstract:BACKGROUND:Testicular cancer survivors (TCS) have an increased risk of treatment-related cardiovascular disease (CVD), which may limit their overall survival. We evaluated the effects of high-intensity aerobic interval training (HIIT) on traditional and novel CVD risk factors and surrogate markers of mortality in a pop...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.30859
更新日期:2017-10-15 00:00:00
abstract::The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome. With this in mind, the relationship between nuclear DNA content and both prognosis and histologic grading according to...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910901)68:5<1095::aid-cncr2820
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:This study assessed the impact of surgical, histopathologic and patient-related factors on the risks of local and distant recurrence and overall survival for patients with stages I through IIIA nonsmall cell lung carcinoma (NSCLC) undergoing definitive resection with or without adjuvant chemotherapy. METHOD...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24133
更新日期:2009-03-01 00:00:00
abstract::Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the two regimens. Comb...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197511)36:5<1589::aid-cncr282036
更新日期:1975-11-01 00:00:00
abstract:BACKGROUND:Although it is believed that p53 suppressor gene mutations, compared with mutations in the K-ras oncogene, occur at a later stage of colorectal tumorigenesis, the distribution of these genetic alterations at an early stage remains poorly characterized. METHODS:The authors analyzed the immunoreactivity for p...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10198
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Medical records of 50 patients with malignant mesothelioma were reviewed to determine the clinical features and factors influencing survival. METHODS:Charts of all patients whose conditions were diagnosed as malignant mesothelioma were abstracted and analyzed by statistical software. RESULTS:The male-to-fe...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19921215)70:12<2969::aid-cncr282
更新日期:1992-12-15 00:00:00
abstract:BACKGROUND:Many trials submitted to scientific meetings are not reported in peer-reviewed journals. Results may vary substantially and the lack of final publication constitutes a form of reporting bias. The authors sought to determine the presentation and publication rates of Phase I trials submitted to a major oncolog...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21337
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:The purpose of the current study was to examine the surgical management of women with borderline ovarian tumors and the adequacy of initial staging according to the guidelines of the International Federation of Gynecology and Obstetrics; to evaluate the impact of restaging operations; and to identify risk fa...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.20098
更新日期:2004-03-15 00:00:00
abstract:BACKGROUND:Patients aged >10 years with rhabdomyosarcoma have an inferior outcome compared with patients ages 1 to 9 years, which may be explained by toxicities (adverse events [AEs]) that result in chemotherapy dose reductions. METHODS:AEs observed during 1 of 3 randomized chemotherapy regimens (vincristine, dactinom...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26358
更新日期:2012-02-15 00:00:00
abstract::A case is reported of a patient with pancreatic carcinoma who developed pancreatic ascites after intraoperative fine-needle aspiration cytology (FNAC) biopsy. This complication of FNAC has not previously been reported to the authors' knowledge. The literature is reviewed, and FNAC is shown to be the safest method of p...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900601)65:11<2537::aid-cncr282
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:Angiogenesis is essential for tumor growth, progression, and metastases. Microvessel density (MVD), a measure of tumor angiogenesis, has been found to have prognostic significance in many tumor types for predicting metastasis and survival. METHODS:Between 1979-1989, 56 cases of FIGO Clinical Stage I and II ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19981001)83:7<1384::aid-cn
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:Accelerated radiotherapy (RT) represents a promising method with which to improve the treatment outcome in patients with head and neck carcinoma. However, its applicability to elderly patients has not been well established. This study assessed treatment toxicities, patient compliance, and oncologic results i...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Patients with prostate cancer receiving androgen deprivation therapy (ADT) are at risk of sleep disturbance; however, to the authors' knowledge, the mechanisms by which ADT may affect sleep are not well understood. The current study compared objective and subjective sleep disturbance in ADT recipients and co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31024
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Full-scale implementation of lung cancer screening in the United States will increase detection of early stages. This study was aimed at assessing the capacity required for treating those cancers. METHODS:A well-established microsimulation model was extended with treatment data from the National Cancer Data...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32026
更新日期:2019-06-15 00:00:00
abstract:BACKGROUND:Despite significant advances in understanding the biology of renal cell carcinoma (RCC) during the past decade, metastatic disease remains nearly incurable and a major medical challenge. Because RCC is known to be immunogenic, immunotherapeutic agents such as recombinant human interleukin-2 (rIL-2) and inter...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0142(19971001)80:7<1198::aid-cn
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:Prognosis of patients with adenocarcinoma of the pancreatic body and tail is extremely poor. Anatomically, this part of the pancreas is thin, and cancerous invasion to the retropancreatic structures occurs easily. The majority of patients have residual tumor in the retroperitoneal tissues after conventional ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960601)77:11<2240::AID-C
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND:In the current study, the authors propose the quantitative Gleason score (qGS), a modification of the current Gleason grading system for prostate cancer, based on the weighted average of Gleason patterns present in the pathology specimen. They hypothesize that the qGS can improve prostate cancer risk stratif...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27670
更新日期:2012-12-15 00:00:00
abstract::A case of coexisting lymphangiosarcoma and Kaposi's sarcoma that occurred in a female renal transplant recipient is presented. Both sarcomas were localized to the skin and were slowly progressive over several years. The coexistence of these two sarcomas may indicate that they arose from a common precursor endothelial ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19911115)68:10<2330::aid-cncr282
更新日期:1991-11-15 00:00:00
abstract:BACKGROUND:Population-based studies suggest that, because of inequalities in treatment, black women with localized endometrial cancer have shorter survival compared with white women. The objective of the current investigation was to determine whether there is a racial disparity in outcome between black patients and whi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23717
更新日期:2008-09-15 00:00:00
abstract::Between March 1973, and December 1976, 22 patients who developed disease progression during or after MOPP therapy were treated with a new combination, B-CAVe (Bleomycin 5 mg/m2 iv days 1, 28, 35; CCNU 100 mg/m2 po day 1; adriamycin 60 mg/m2 iv day 1; and vinblastine 5 mg/m2 iv day 1). Objective responses were achieved...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<1670::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract:BACKGROUND:It remains unclear whether primary tumor resection benefits patients with metastatic neuroblastoma. The authors assessed the impact of extent and timing of resection on outcome in these patients. METHODS:The authors reviewed the records of 124 patients > 1 year of age at diagnosis of International Neuroblas...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21566
更新日期:2005-12-15 00:00:00
abstract:BACKGROUND:Electrochemotherapy (ECT) is a new antitumor approach that combines systemic bleomycin (BLM) with electric pulses (EP) delivered locally at the tumor site. These EP permeabilize the cells in the tissue, allow BLM delivery inside the cells, and increase BLM cytotoxicity. As an extension of our initial Phase I...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19960301)77:5<956::aid-cnc
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Melanoma is the most lethal form of skin cancer, with an estimated 68,130 new cases and 8700 deaths in the United States in 2010. The increasing incidence and high death rate associated with metastatic disease support the need to focus on prevention. The authors used data from the Women's Health Initiative (...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27497
更新日期:2012-10-15 00:00:00
abstract::This report describes a patient with small-cell carcinoma of the lung associated with blindness. The serum of this patient was tested for immunoreactivity with retinal sections because there was no evidence of tumor metastasis to the central nervous system and because neuroendocrine cells of the lung share common anti...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19821001)50:7<1289::aid-cncr2820
更新日期:1982-10-01 00:00:00