VAB-3 combination chemotherapy of metastatic testicular cancer.

abstract：:The records of 134 patients with small-cell lung cancer who had been seen at Henry Ford Hospital between 1972-1979 were reviewed with emphasis on brain metastasis. Brain metastasis developed in 28% of the patients; 21% had brain metastasis at the time of diagnosis and in 7% it developed later (de novo). In 9%, the chi...

journal_title：Cancer

authors： Doyle TJ

更新日期：1982-08-15 00:00:00

abstract：BACKGROUND:The human papillomavirus (HPV) E2 protein is a transcriptional repressor of the oncogenes E6/E7 and loss of E2 function is considered a key step in carcinogenesis. Integration of HPV into the host genome may disrupt the E2 gene. Furthermore, methylation of CpG dinucleotides in E2-binding sites (E2BSs) in the...

journal_title：Cancer

authors： Reuschenbach M,Huebbers CU,Prigge ES,Bermejo JL,Kalteis MS,Preuss SF,Seuthe IM,Kolligs J,Speel EJ,Olthof N,Kremer B,Wagner S,Klussmann JP,Vinokurova S,von Knebel Doeberitz M

更新日期：2015-06-15 00:00:00

abstract：BACKGROUND:Intensity-modulated radiation therapy (IMRT) is a novel approach to the planning and delivery of radiation therapy. The prevalence of IMRT use among radiation oncologists in the U.S. appears to be increasing, despite limited data evaluating its risks and benefits. METHODS:A random sample of radiation oncolo...

journal_title：Cancer

authors： Mell LK,Mehrotra AK,Mundt AJ

更新日期：2005-09-15 00:00:00

abstract：BACKGROUND:Previously, the patient-reported Total Illness Burden Index for Prostate Cancer (TIBI-CaP) questionnaire and/or the physician-reported Charlson Comorbidity Index (CCI) have provided assessments of competing comorbidity during treatment decisions for patients with prostate cancer. In the current study, the au...

journal_title：Cancer

authors： Liss MA,Billimek J,Osann K,Cho J,Moskowitz R,Kaplan A,Szabo RJ,Kaplan SH,Greenfield S,Dash A

更新日期：2013-07-01 00:00:00

abstract：:The clinical findings in 262 patients with melanoma were correlated with an assessment of their cellular-mediated immunity by delayed-type hypersensitivity (DTH) skin tests, by lymphocyte blastogenesis, and by leukocyte enumerations. Patients with systemic metastases (stage IV) and those with evidence of tumor burden ...

journal_title：Cancer

authors： Pritchard DJ,Ritts RE Jr,Taylor WF,Miller GC

更新日期：1978-06-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) values in 529 patients treated in two consecutive adjuvant chemotherapy protocols were analyzed to determine if CEA values correlated with disease-free status or prognostic utility. CEA values were evaluated preoperatively, before chemotherapy, at the conclusion of chemotherapy, and duri...

journal_title：Cancer

authors： Theriault RL,Hortobagyi GN,Fritsche HA,Frye D,Martinez R,Buzdar AU

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Screening is effective in reducing the incidence and mortality of colorectal cancer. Rates of colorectal cancer test use continue to be low. METHODS:The authors analyzed data from the National Health Interview Survey concerning the use of the home-administered fecal occult blood test (FOBT) and sigmoidoscop...

journal_title：Cancer

authors： Seeff LC,Nadel MR,Klabunde CN,Thompson T,Shapiro JA,Vernon SW,Coates RJ

更新日期：2004-05-15 00:00:00

abstract：BACKGROUND:The authors have previously reported a tumor cell vaccine modified with superantigen staphylococcal enterotoxin A (SEA) and its antitumor effect. The tumor cell vaccines modified with multiple immune activators frequently elicited stronger immune responses against established tumors than single-modified vacc...

journal_title：Cancer

authors： Yi P,Yu H,Ma W,Wang Q,Minev BR

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The current study evaluated the efficacy of a 10-week, group-based, cognitive-behavioral stress management (CBSM) intervention relative to a half-day seminar in improving quality of life (QoL) among men who were treated for localized prostate carcinoma (PC) with either radical prostatectomy (RP) or radiation...

journal_title：Cancer

authors： Penedo FJ,Dahn JR,Molton I,Gonzalez JS,Kinsinger D,Roos BA,Carver CS,Schneiderman N,Antoni MH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:To identify potential genetic markers for severe oxaliplatin-induced chronic peripheral neuropathy (OXCPN), the authors performed a genome-wide association analysis of patients with colon cancer who received oxaliplatin-based chemotherapy. METHODS:This was a prospective study in which DNA was purified in pe...

journal_title：Cancer

authors： Won HH,Lee J,Park JO,Park YS,Lim HY,Kang WK,Kim JW,Lee SY,Park SH

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:A considerable body of evidence supports the concept that a significant number of cutaneous malignant melanomas progress through a precursor lesion or dysplastic melanocytic nevi (DN). Tumor angiogenesis likely plays a critical role in early development of melanoma, and intermediate biomarkers of angiogenesi...

journal_title：Cancer

authors： Einspahr JG,Thomas TL,Saboda K,Nickolof BJ,Warneke J,Curiel-Lewandrowski C,Ranger-Moore J,Duckett L,Bangert J,Fruehauf JP,Alberts DS

更新日期：2007-12-01 00:00:00

abstract：:Estrogen receptors in breast tumors were assayed in 55 premenopausal women undergoing bilateral oophorectomy and in 120 postmenopausal women undergoing bilateral adrenalectomy for treatment of metastatic breast cancer. The data show that 20 (60%) of the 32 patients with estrogen receptor-positive (ER+) tumors had obje...

journal_title：Cancer

authors： Dao TL,Nemoto T

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:The outcome of surgical treatment for early gastric cancer (EGC) generally is considered to be satisfactory. Although a small percentage of patients experience disease recurrence, the absolute number of such instances is too small for assessment of risk factors. METHODS:The authors investigated the follow-u...

journal_title：Cancer

authors： Sano T,Sasako M,Kinoshita T,Maruyama K

更新日期：1993-12-01 00:00:00

abstract：:Quality assurance for the management of multicenter clinical trials requires timely patient and data accrual and consistency with design parameters. Data from central pathology review, treatment modality, and follow-up as well as trial end points direct the selection of appropriate compliance measures. To integrate th...

journal_title：Cancer

authors： Pollock BH

更新日期：1994-11-01 00:00:00

abstract：:Three bleomycin-resistant (BLMr) human carcinoma cell lines (HeLa-BLMr, KB-BLMr, and Hepd-uvBLMr) were established in culture by progressively increasing the concentration of bleomycin (BLM). HeLa-BLMr and KB-BLMr were obtained after 5 and 2 months of incubation with BLM, whereas the establishment of Hepd-uvBLMr requi...

journal_title：Cancer

authors： Urade M,Sugi M,Miyazaki T

更新日期：1988-04-15 00:00:00

abstract：:A 30-year Memorial Hospital experience with 146 patients with malignant mixed tumor is reviewed. These comprised 5% of 2,743 patients who were treated for salivary neoplasms from 1939 through 1968. The tumors arose in the parotid gland in 108 patients, submaxillary gland in 23 patients, mucus or so-called minor saliva...

journal_title：Cancer

authors： Spiro RH,Huvos AG,Strong EW

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Myoepithelial carcinoma, also know as malignant myoepithelioma, is rare in the salivary gland, and its cytologic features have rarely been reported. DESIGN:Four cases of myoepithelial carcinoma with cytology were retrieved from the archives of the Pathology Departments of two academic institutes. In three c...

journal_title：Cancer

authors： Chhieng DC,Paulino AF

更新日期：2002-02-25 00:00:00

abstract：BACKGROUND:Immune checkpoint inhibitors (ICIs) represent an appealing treatment for patients with advanced urothelial cancer (aUC) and a poor performance status (PS). However, the benefit of ICIs for patients with a poor PS remains unknown. It was hypothesized that a poor Eastern Cooperative Oncology Group (ECOG) PS (≥...

journal_title：Cancer

authors： Khaki AR,Li A,Diamantopoulos LN,Bilen MA,Santos V,Esther J,Morales-Barrera R,Devitt M,Nelson A,Hoimes CJ,Shreck E,Assi H,Gartrell BA,Sankin A,Rodriguez-Vida A,Lythgoe M,Pinato DJ,Drakaki A,Joshi M,Isaacsson Velho P

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:Although aging is one of the most important risk factors for cancer, elderly patients tend to be excluded from cancer clinical trials, only on the basis of chronologic age. Performance Status (PS) has been used widely to select adult patients for entry into clinical trials, but it does not include a comprehe...

journal_title：Cancer

authors： Monfardini S,Ferrucci L,Fratino L,del Lungo I,Serraino D,Zagonel V

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:It is unclear whether patients with Stage II colon carcinoma should be offered adjuvant chemotherapy. Therefore, the authors analyzed the risk factors of these patients to identify high-risk subgroups who may benefit from such treatment. METHODS:The data from 305 patients with Stage II colon carcinoma docum...

journal_title：Cancer

authors： Merkel S,Wein A,Günther K,Papadopoulos T,Hohenberger W,Hermanek P

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:The current study was performed to evaluate prognostic factors for overall survival (OS), distant metastasis (DM), and local failure (LF) in patients with Stage II/III esophageal carcinoma. METHODS:The following potential prognostic factors were retrospectively investigated in 124 patients treated with radi...

journal_title：Cancer

authors： Rades D,Schild SE,Bahrehmand R,Zschenker O,Alberti WA,Rudat VR

更新日期：2005-04-15 00:00:00

abstract：:Data from a hospital-based case-control study between 1985-1990 were used to examine the effects of tobacco, alcohol, asbestos, and other occupational exposures on laryngeal cancer risk in 194 white men with primary cancer of the larynx and 184 age-matched control subjects. A dose-dependent effect for current cigarett...

journal_title：Cancer

authors： Muscat JE,Wynder EL

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Adenoid cystic carcinoma (ACC) of the head and neck (ACCHN) is a rare tumor of minor salivary, parotid, and submandibular glands. The biologic behavior of the disease is poorly understood, and nonsurgical treatment strategies have yet to be standardized. The long-term prognosis continues to be guarded, with ...

journal_title：Cancer

authors： Ellington CL,Goodman M,Kono SA,Grist W,Wadsworth T,Chen AY,Owonikoko T,Ramalingam S,Shin DM,Khuri FR,Beitler JJ,Saba NF

更新日期：2012-09-15 00:00:00

abstract：:A retrospective study was done of all patients who were seen for definitive treatment of adenocarcinoma of the pancreas at the Massachusetts General Hospital from 1963 to 1973. There were a total of 145 patients. Thirty-one patients were treated with radical surgery, with a 16% operative mortality, a 5-year crude surv...

journal_title：Cancer

authors： Tepper J,Nardi G,Sutt H

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Increasingly, the quality of life (QOL) of women diagnosed with breast carcinoma is being studied. However, there is little information regarding long term survivors among ethnic minority women. The purpose of this study was to describe the QOL of long term breast carcinoma survivors (BCS) and to examine the...

journal_title：Cancer

authors： Ashing-Giwa K,Ganz PA,Petersen L

更新日期：1999-01-15 00:00:00

abstract：BACKGROUND:Recently, the authors identified molecular signatures and pathways associated with nonsmall cell lung carcinoma histology and lung development. They hypothesized that genetic classifiers of histology would provide insight into lung tumorigenesis and would be associated with clinical outcome when evaluated in...

journal_title：Cancer

authors： Shah L,Walter KL,Borczuk AC,Kawut SM,Sonett JR,Gorenstein LA,Ginsburg ME,Steinglass KM,Powell CA

更新日期：2004-10-01 00:00:00

abstract：:Peripheral B- and T-lymphocyte counts were studied in 50 patients before they received any therapy for their conditions: 16 had carcinoma of the breast; 8 soft tissue sarcoma; and 26, benign disease. Among 11 males, the six patients with advanced soft tissue sarcoma had significantly lower percentages of T lymphocytes...

journal_title：Cancer

authors： Lee YT,Marshall GJ,Weiner J,Bateman JR

更新日期：1977-08-01 00:00:00

abstract：:The role of amsacrine in inducing remission in patients with cardiac disease and acute leukemia was evaluated. There were 17 patients with acute myelogenous leukemia (AML), six with acute lymphocytic leukemia (ALL), and one with biphenotypic leukemia. In this series of 24 patients whose disease had relapsed and who ha...

journal_title：Cancer

authors： Arlin ZA,Feldman EJ,Mittelman A,Ahmed T,Puccio C,Chun HG,Cook P,Baskind P,Marboe C,Mehta R

更新日期：1991-09-15 00:00:00

abstract：:To determine the efficacy of adjuvant chemotherapy in patients with advanced head and neck squamous carcinoma, the National Cancer Institute initiated a multi-institutional, prospective randomized trial termed the Head and Neck Contracts Program. Between 1978 and 1982, 462 patients with resectable Stage III or IV canc...

journal_title：Cancer

authors：

更新日期：1987-08-01 00:00:00

abstract：:A case of a glomus tumor arising in an unusual site, the trachea, is described. The tumor was composed of a mixture of glomus cells and mast cells. At the ultrastructural level, the glomus cells exhibited features of modified smooth-muscle cells. ...

journal_title：Cancer

authors： Fabich DR,Hafez GR

更新日期：1980-05-01 00:00:00