Intrahepatic infusional therapy for metastatic ovarian carcinoma.

abstract：BACKGROUND:Novel approaches to increasing the therapeutic efficacy of targeted radiotherapy of cancer are required. One strategy to achieve this goal is to induce high-level expression of a receptor on the surface of tumor cells that can be targeted with a radiolabeled peptide. The objectives of this study were to 1) i...

journal_title：Cancer

authors： Rogers BE,Zinn KR,Lin CY,Chaudhuri TR,Buchsbaum DJ

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:The first step of colorectal carcinoma spread depends on the ability of the tumor cells to degrade and invade the extracellular matrix (ECM). The objectives of the current study were to evaluate the serum pattern of laminin, C-terminal peptide of Type I (PIP), and N-terminal peptide of Type III (PIIIP) proco...

journal_title：Cancer

authors： Plebani M,Basso D,Roveroni G,De Paoli M,Galeotti F,Corsini A

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Despite advances in first-line therapy, there are few data on treatment of glioblastoma multiforme (GBM) at recurrence. Temozolomide (TMZ) is well tolerated and may have activity despite prior TMZ exposure if novel dose schedules are used. METHODS:The authors reviewed their experience with a continuous TMZ ...

journal_title：Cancer

authors： Perry JR,Rizek P,Cashman R,Morrison M,Morrison T

更新日期：2008-10-15 00:00:00

abstract：BACKGROUND:To evaluate the immunologic activity of regional lymph nodes, the phenotype of lymphocytes and the functional expression of cell adhesion molecules (CAMs) on lymph node lymphocytes (LNL-: uninvolved, LNL+: involved) were investigated in patients with gastrointestinal carcinoma. METHODS:The lymphocyte subpop...

journal_title：Cancer

authors： Shinkal H,Kitayama J,Kimura W,Muto T,Shibata Y

更新日期：1996-10-15 00:00:00

abstract：BACKGROUND:Stepwise progression of peripheral-type lung adenocarcinoma was characterized morphologically and was related to prognosis. Expression of the tumor suppressor gene p16 in pulmonary adenocarcinoma decreased, mainly as a result of aberrant methylation of the CpG islands of the promoter region. METHODS:Aberran...

journal_title：Cancer

authors： Tanaka R,Wang D,Morishita Y,Inadome Y,Minami Y,Iijima T,Fukai S,Goya T,Noguchi M

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Pegylated liposomal doxorubicin (PEG-LD) and docetaxel have single-agent activity in several malignancies. The authors conducted a Phase I trial to evaluate the maximum tolerated dose (MTD), toxicities, and effect of dose sequencing of this combination in patients with advanced malignancies. METHODS:Twenty-...

journal_title：Cancer

authors： Fracasso PM,Rodriguez LC,Herzog TJ,Fears CL,Goodner SA,Govindan R,Picus J,Rader JS,Tan BR,Arquette MA

更新日期：2003-08-01 00:00:00

abstract：:Data are presented on mortality from neoplasms as determined from death certificates in a cohort of 8393 college men, according to athletic status in college. Major athletes (lettermen) died significantly more often from neoplasms than nonathletes. Mean age at death from neoplasms (underlying cause) was significantly ...

journal_title：Cancer

authors： Polednak AP

更新日期：1976-07-01 00:00:00

abstract：:Carcinoma of the breast is a disease that is associated with 10-year recurrence rates of 25% in operable patients with no spread to the axillary nodes and 75% in patients in whom the tumor has extended to the axillary nodes. Locoregional recurrence rates of close to 50% have been reported in patients with Stage III di...

journal_title：Cancer

authors： Marcial VA

更新日期：1994-07-01 00:00:00

abstract：:A new Hodgkin's cell line, designated HD-70, was established from the peripheral blood of a 69-year-old man with Hodgkin's disease of nodular sclerosing type. The cell line grows in a single cell suspension and has a doubling time of 28 hours. The cells have a round or irregular nucleus or multiple nuclei in relativel...

journal_title：Cancer

authors： Kanzaki T,Kubonishi I,Eguchi T,Yano S,Sonobe H,Ohyashiki JH,Ohyashiki K,Toyama K,Ohtsuki Y,Miyoshi I

更新日期：1992-02-15 00:00:00

abstract：:The authors performed immunohistochemical and cytogenetic studies in a 73-year old man with malignant angioendotheliomatosis. The patient was referred for evaluation of fever of unknown origin, hepatic failure, and neurologic deterioration. Examination of a muscle biopsy revealed numerous, noncohesive atypical mononuc...

journal_title：Cancer

authors： Molina A,Lombard C,Donlon T,Bangs CD,Dorfman RF

更新日期：1990-08-01 00:00:00

abstract：:Activities of glucosephosphate isomerase, lactate dehydrogenase, and NADP-isocitrate dehydrogenase were significantly elevated in breast cancer specimens from patients who responded favorably to combination cytotoxic chemotherapy regimens compared with those in carcinomas from patients failing to respond to the same c...

journal_title：Cancer

authors： Hilf R,Savlov ED,Rector WD,Wittliff JL

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:The effect on prognosis of adding imatinib mesylate to the treatment of patients with Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML) has not been explored fully. The objective of the current study was to evaluate the benefit of adding imatinib to the treatment sequence of patients w...

journal_title：Cancer

authors： Kantarjian H,O'Brien S,Cortes J,Shan J,Giles F,Garcia-Manero G,Verstovsek S,Faderl S,Rios MB,Talpaz M

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Response rates to second-line chemotherapy in recurrent high-grade glial tumors are low and new effective treatments are needed. The objective of this study was to evaluate response rates and tolerability of chemotherapy with bevacizumab and irinotecan in recurrent high-grade gliomas. METHODS:Twenty patient...

journal_title：Cancer

authors： Bokstein F,Shpigel S,Blumenthal DT

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:Antibacterial prophylaxis with quinolone antibiotics has resulted in an increase in streptococcal infections among bone marrow transplantation (BMT) recipients with myelosuppression. Oral ulceration (mucositis), which frequently occurs as a consequence of chemotherapy, has been implicated as a significant po...

journal_title：Cancer

authors： Ruescher TJ,Sodeifi A,Scrivani SJ,Kaban LB,Sonis ST

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine local definitive therapy for nonmetastatic breast cancer with the Patterns of Care Breast and Prostate Cancer (POCBP) study of the National Program of Cancer Registries (Centers for Disease Control and Prevention). METHODS:POCBP medical record data were re-abstracted...

journal_title：Cancer

authors： Anderson RT,Morris CR,Kimmick G,Trentham-Dietz A,Camacho F,Wu XC,Sabatino SA,Fleming ST,Lipscomb J

更新日期：2015-03-01 00:00:00

abstract：:A 12-year-old boy with primary reticulum cell sarcoma of the testis who is alive and free of tumor 32 months after orchiectomy, radiation therapy to inguinal, iliac and retroperitoneal lymph nodes and chemotherapy is reported. Seven previously documented cases of childhood primary testicular lymphoma are reviewed. The...

journal_title：Cancer

authors： Weitzner S,Gropp A

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Since endoscopic treatment was first evaluated and established as a treatment for patients with early stage gastric carcinoma, metachronous disease recurrence at other sites in the stomach after endoscopic treatment has become a major problem. METHODS:A retrospective case-control study was conducted on 10 p...

journal_title：Cancer

authors： Kawamura A,Adachi K,Ishihara S,Katsube T,Takashima T,Yuki M,Amano K,Fukuda R,Yamashita Y,Kinoshita Y

更新日期：2001-01-15 00:00:00

abstract：BACKGROUND:Quality of life (QOL) issues in patients with head and neck carcinoma are of importance beyond the incidence of these tumors because of the impact of the disease and its treatment on external appearance and function of the upper aerodigestive tract. Nasopharyngeal carcinoma (NPC) patients comprise a unique s...

journal_title：Cancer

authors： Talmi YP,Horowitz Z,Bedrin L,Wolf M,Chaushu G,Kronenberg J,Pfeffer MR

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:The incidence of basal cell carcinoma (BCC) in a defined population is unknown. METHODS:The incidence of histologically diagnosed cases of BCC in a defined population of a city in southern Sweden was studied. Four 2-year periods were examined from 1970 to 1986. Cases from 1970 and 1980 were reexamined micro...

journal_title：Cancer

authors： Dahl E,Aberg M,Rausing A,Rausing EL

更新日期：1992-07-01 00:00:00

abstract：:Twenty-two patients received specific active immunotherapy (TAA vaccine once per month for 3 months), with the duration of follow-up, as of July 1984, ranging from 3 months to 36 months (median, 21 months). Of these, seven had Dukes B2, seven had Dukes C, and eight had Dukes D lesions. All received surgical resection,...

journal_title：Cancer

authors： Hollinshead A,Elias EG,Arlen M,Buda B,Mosley M,Scherrer J

更新日期：1985-08-01 00:00:00

abstract：:Although cancer often is referred to as "a disease of the genes," it is indisputable that the (epi)genetic properties of individual cancer cells are highly variable, even within the same tumor. Hence, preexisting resistant clones will emerge and proliferate after therapeutic selection that targets sensitive clones. He...

journal_title：Cancer

authors： Napel S,Mu W,Jardim-Perassi BV,Aerts HJWL,Gillies RJ

更新日期：2018-12-15 00:00:00

abstract：:The histologic findings of five patients with clinically typical Bowenoid dysplasia (BD) allowed the authors to classify the vulvar and perineal biopsies of 18 patients under 40 years as BD and the vulvar biopsies of six patients under 40 years as squamous cell carcinoma in situ (CIS). The two best criteria for BD are...

journal_title：Cancer

authors： Ulbright TM,Stehman FB,Roth LM,Ehrlich CE,Ransburg RC

更新日期：1982-12-15 00:00:00

abstract：BACKGROUND:The high mortality associated with ovarian carcinoma is largely a reflection of the inability to diagnose the disease at an early stage; the identification of a histologic lesion or molecular marker associated early stages of transformation would represent an important advance in understanding the natural hi...

journal_title：Cancer

authors： Barakat RR,Federici MG,Saigo PE,Robson ME,Offit K,Boyd J

更新日期：2000-07-15 00:00:00

abstract：:Tissue specimens from five patients with rheumatic disease who developed lymphadenopathy were studied by an immunoperoxidase method; available biopsy material was examined for cytoplasmic immunoglobulin determinants. Three patients had follicular hyperplasia of lymph nodes with polyclonal patterns. Two patients with S...

journal_title：Cancer

authors： Humphrey DM,Cortez EA,Spiva DA

更新日期：1982-05-15 00:00:00

abstract：:Female genital tract involvement by hematologic neoplasms is uncommon and is usually associated with disseminated disease. Lymphoid neoplasms, which involve the cervix and uterus primarily, are usually of either diffuse large cell or small cleaved cell type, and rarely Burkitt's (small non-cleaved) lymphoma or granulo...

journal_title：Cancer

authors： Zutter MM,Gersell DJ

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The authors undertook a prospective evaluation of the clinical value of 2-fluoro [18-]-2-deoxyglucose positron emission tomography (FDG-PET) in the detection and staging of malignant lymphoma compared with computed tomography (CT) and bone marrow biopsy (BMB). METHODS:Fifty-two consecutive patients with unt...

journal_title：Cancer

authors： Buchmann I,Reinhardt M,Elsner K,Bunjes D,Altehoefer C,Finke J,Moser E,Glatting G,Kotzerke J,Guhlmann CA,Schirrmeister H,Reske SN

更新日期：2001-03-01 00:00:00

abstract：:To remove regionally recurrent cancer of the rectum completely, more radical extensive resections were attempted than the conventional ones in 35 patients. Twenty-two patients underwent total pelvic exenteration. In 23, sacral resection was done, combined with other procedures including excision of the entire circumfe...

journal_title：Cancer

authors： Maetani S,Nishikawa T,Iijima Y,Tobe T,Kotoura Y,Shikata J,Yamamura T

更新日期：1992-06-15 00:00:00

abstract：BACKGROUND:The authors sought to determine whether differences existed in patterns of outcome and morbidity between the 3 thigh compartments after limb-sparing surgery and postoperative radiation therapy (RT). METHODS:A total of 255 patients with primary soft tissue sarcoma (STS) of the thigh were identified in our sa...

journal_title：Cancer

authors： Rimner A,Brennan MF,Zhang Z,Singer S,Alektiar KM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Although pediatric cancer mortality and survival have improved in the United States over the past 40 years, differences exist by age, race/ethnicity, cancer site, and economic status. To assess progress, this study examined recent mortality and survival data for individuals younger than 20 years. METHODS:Ag...

journal_title：Cancer

authors： Siegel DA,Richardson LC,Henley SJ,Wilson RJ,Dowling NF,Weir HK,Tai EW,Buchanan Lunsford N

更新日期：2020-10-01 00:00:00

abstract：:Despite few effective therapies, only a small percentage of patients diagnosed with myelodysplastic syndromes (MDS) in the United States are enrolled in prospective, interventional clinical trials. MDS-specific barriers to trial accrual include a high frequency of elderly patients with comorbid conditions, atypical di...

journal_title：Cancer

authors： Steensma DP,Brunner AM,DeZern AE,Garcia-Manero G,Komrokji RS,Odenike OS,Roboz GJ,Savona MR,Stone RM,Sekeres MA

更新日期：2018-12-15 00:00:00