Phase II study of patients with metastatic nonsmall cell carcinoma of the lung treated with paclitaxel by 3-hour infusion.

abstract：:Six patients with metastatic mixed germ-cell tumors who had been treated successfully with chemotherapy had recurring solitary enlarging masses. Four had enlarging pulmonary masses and two patients had enlarging abdominal masses. Each had the presumed chemotherapy refractory mass surgically resected and was found to h...

journal_title：Cancer

authors： Logothetis CJ,Samuels ML,Trindade A,Johnson DE

更新日期：1982-10-15 00:00:00

abstract：:Meningeal carcinomatosis can appear with a variety of neurologic signs and symptoms. Alterations in respiratory control have not been reported in this syndrome or in neurologic syndromes associated with systemic cancer. The authors report on a case of documented leptomeningeal carcinoma from breast cancer presenting a...

journal_title：Cancer

authors： Marcus FS,Dandolos EM,Friedman MA

更新日期：1981-03-01 00:00:00

abstract：:The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow-up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was f...

journal_title：Cancer

authors： Farley FA,Healey JH,Caparros-Sison B,Godbold J,Lane JM,Glasser DB

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:To compare the diagnostic value of thoracoscopic biopsy, fluid cytology, and Abrams needle biopsy, the authors analyzed prospectively the records of 188 patients with malignant pleural mesothelioma examined between 1973 and 1990. Symptoms were pleural effusion in 173 patients, empyema in 1, spontaneous pneum...

journal_title：Cancer

authors： Boutin C,Rey F

更新日期：1993-07-15 00:00:00

abstract：:Ninety-two cases of granulosa cell tumor of the ovary have been studied. The clinical and pathologic data from this group were similar to that obtained in previous series. Because of the long natural history of many granulosa cell tumors, crude death rates over a relatively short period give little indication of the t...

journal_title：Cancer

authors： Fox H,Agrawal K,Langley FA

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:A subset of patients with diffuse gastric cancer harbor deleterious cancer-causing germline mutations in the type 1 E-cadherin (epithelial) gene (CDH1), which predisposes to the autosomal dominantly inherited hereditary diffuse gastric cancer (HDGC) syndrome. These mutations are associated with a 70% life-ti...

journal_title：Cancer

authors： Lynch HT,Kaurah P,Wirtzfeld D,Rubinstein WS,Weissman S,Lynch JF,Grady W,Wiyrick S,Senz J,Huntsman DG

更新日期：2008-06-15 00:00:00

abstract：BACKGROUND:We recently reported that peroxisome proliferator-activated receptor γ agonists target chronic myeloid leukemia (CML) quiescent stem cells in vitro by decreasing transcription of STAT5. Here in the ACTIM phase 2 clinical trial, we asked whether pioglitazone add-on therapy to imatinib would impact CML residua...

journal_title：Cancer

authors： Rousselot P,Prost S,Guilhot J,Roy L,Etienne G,Legros L,Charbonnier A,Coiteux V,Cony-Makhoul P,Huguet F,Cayssials E,Cayuela JM,Relouzat F,Delord M,Bruzzoni-Giovanelli H,Morisset L,Mahon FX,Guilhot F,Leboulch P,French

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:As an organized screening program, the national Breast and Cervical Cancer Early Detection Program (BCCEDP) was launched in the early 1990s to improve breast cancer outcomes among underserved women. To analyze the impact of the BCCEDP on breast cancer outcomes in Ohio, this study compared cancer stages and m...

journal_title：Cancer

authors： Koroukian SM,Bakaki PM,Htoo PT,Han X,Schluchter M,Owusu C,Cooper GS,Rose J,Flocke SA

更新日期：2017-08-15 00:00:00

abstract：:The records of 314 children with acute lymphocytic leukemia (ALL) were reviewed to determine the frequency, clinical and laboratory features; contributing factors; and prognosis of cyclophosphamide-induced hemorrhagic cystitis. Twenty-five well-documented cases of hemorrhagic cystitis were identified. While most of th...

journal_title：Cancer

authors： Lawrence HJ,Simone J,Aur RJ

更新日期：1975-11-01 00:00:00

abstract：:A primitive neuroectodermal tumor of peripheral nerve origin was examined by light and electron microscopy. The lesion arose in association with the S1 nerve root of the lumbosacral plexus in a 22-year-old female. Following a surgical biopsy, the patient received systemic chemotherapy; however, approximately one-and-a...

journal_title：Cancer

authors： Bolen JW,Thorning D

更新日期：1980-12-01 00:00:00

abstract：:This study sought to replicate and expand findings reported by the National Surgical Adjuvant Breast and Bowel Project (NSABP) on prognostic factors in resectable colon cancer. Mantel-Haenszel tests and the Cox model were used to analyze prognostic significance and effect of primary disease symptoms and tumor location...

journal_title：Cancer

authors： Steinberg SM,Barkin JS,Kaplan RS,Stablein DM

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Ovarian surface epithelial cells are positionally organized as a single cell layer by a sheet of basement membrane. It is believed that the contact of the ovarian surface epithelial cells with the basement membrane regulates cell growth and ensures the organization of the epithelium. Disabled-2 (Dab2), a sig...

journal_title：Cancer

authors： Capo-Chichi CD,Smith ER,Yang DH,Roland IH,Vanderveer L,Cohen C,Hamilton TC,Godwin AK,Xu XX

更新日期：2002-10-15 00:00:00

abstract：BACKGROUND:: Invasive aspergillosis (IA) is a common complication in patients with hematologic malignancies. Patients with solid tumors also are at risk for IA because they may develop neutropenia as a result of chemotherapy and radiotherapy. However, studies of IA in patients with solid tumors are rare. In this study,...

journal_title：Cancer

authors： Yan X,Li M,Jiang M,Zou LQ,Luo F,Jiang Y

更新日期：2009-11-01 00:00:00

abstract：:The assumption that asymptomatic colorectal cancers bleed provides the rationale for widespread stool screening. The authors studied 12 patients with unoperated colorectal cancer but without colorectal symptoms and six healthy volunteers as laboratory controls. All stools were collected for 2 weeks and analyzed by the...

journal_title：Cancer

authors： Ahlquist DA,McGill DB,Fleming JL,Schwartz S,Wieand HS,Rubin J,Moertel CG

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:The authors undertook a prospective evaluation of the clinical value of 2-fluoro [18-]-2-deoxyglucose positron emission tomography (FDG-PET) in the detection and staging of malignant lymphoma compared with computed tomography (CT) and bone marrow biopsy (BMB). METHODS:Fifty-two consecutive patients with unt...

journal_title：Cancer

authors： Buchmann I,Reinhardt M,Elsner K,Bunjes D,Altehoefer C,Finke J,Moser E,Glatting G,Kotzerke J,Guhlmann CA,Schirrmeister H,Reske SN

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Gastric carcinoma with lymphoid stroma (GCLS) has been reported to have a more favorable prognosis than ordinary gastric carcinoma, however, the precise mechanism of the pathogenesis for GCLS remains unclear. METHODS:The authors analyzed 99 GCLS in 94 patients for Epstein-Barr virus (EBV) sequences using po...

journal_title：Cancer

authors： Nakamura S,Ueki T,Yao T,Ueyama T,Tsuneyoshi M

更新日期：1994-05-01 00:00:00

abstract：:To determine whether steroid hormone receptor expression is clinically relevant in ovarian cancer, cytoplasmic and nuclear estrogen (ER) and progesterone (PR) receptor levels have been measured and their concentration calculated by Scatchard analysis. Of 89 samples from patients with non-pretreated epithelial ovarian ...

journal_title：Cancer

authors： Harding M,Cowan S,Hole D,Cassidy L,Kitchener H,Davis J,Leake R

更新日期：1990-02-01 00:00:00

abstract：:Exposure of tumor cells to reduced folates before or with the fluoropyrimidines, 5-fluorouracil or 5-fluoro-2'deoxyuridine, results in a substantial increase in the activity of these drugs. Available evidence suggests that the mechanism of this synergism is a kinetic stabilization of complex formed between thymidylate...

journal_title：Cancer

authors： Morgan RG

更新日期：1989-03-15 00:00:00

abstract：:Acute non-lymphocytic leukemia occurred in eight women following long-term treatment with Treosulfan (= dihydroxybusulfan) for ovarian carcinoma. The leukemia developed from 21 to 58 months (median 50 months) after the institution of chemotherapy. At the time when the leukemia appeared seven of the patients were in co...

journal_title：Cancer

authors： Pedersen-Bjergaard J,Nissen NI,Sørensen HM,Hou-Jensen K,Larsen MS,Ernst P,Ersbøl J,Knudtzon S,Rose C

更新日期：1980-01-01 00:00:00

abstract：:The authors observed the clinical course of 24 women with surgically removed prolactinomas for a mean postoperative interval of 62 months. The frequency of late tumor recurrence and probable factors responsible for the recurrence were investigated. Hyperprolactinemia recurred in 4 of 13 patients with microadenomas (31...

journal_title：Cancer

authors： Parl FF,Cruz VE,Cobb CA,Bradley CA,Aleshire SL

更新日期：1986-06-15 00:00:00

abstract：BACKGROUND:The purpose of the current study was to test the hypothesis that a lower clinical TNM stage is associated with a higher rate of pathologic complete response (pathCR) in patients with esophageal carcinoma receiving preoperative chemoradiotherapy and to determine whether outcome after pathCR is related to clin...

journal_title：Cancer

authors： Rohatgi P,Swisher SG,Correa AM,Wu TT,Liao Z,Komaki R,Walsh GL,Vaporciyan AA,Rice DC,Roth JA,Ajani JA

更新日期：2005-12-01 00:00:00

abstract：:Plasma CEA concentration before and after administration of secretin and cholecystokinin-pancreozymin has been determined in 89 patients with neoplastic or inflammatory pancreatric disease and other neoplastic and nonneoplastic disorders. The purpose of the study was to expore the specificity and sensitivity of such a...

journal_title：Cancer

authors： Lindstedt G,Lundberg PA,Rolny P

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Specialty of the endoscopist has been related to the postcolonoscopy interval risk of colorectal cancer (CRC). However, the impact of such a difference on the long-term CRC prevention rate by screening colonoscopy is largely unknown. METHODS:A Markov model was constructed to simulate the efficacy and cost o...

journal_title：Cancer

authors： Hassan C,Rex DK,Zullo A,Cooper GS

更新日期：2012-09-15 00:00:00

abstract：:The records were reviewed for all patients hospitalized at a pediatric oncology center for complications of leukemia (n = 822) or lymphoma (n = 290) during an 8-year period. The results of surveillance cultures (throat, rectal, and urine) and blood cultures were analyzed to identify cases of Candida tropicalis and C. ...

journal_title：Cancer

authors： Marina NM,Flynn PM,Rivera GK,Hughes WT

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:In a previous study of gene array data, the authors identified survivin as a candidate marker of aggressiveness in clear cell renal cell carcinoma (ccRCC). What remained in question was whether survivin expression at the protein level is an independent predictor of disease progression and cancer-specific sur...

journal_title：Cancer

authors： Parker AS,Kosari F,Lohse CM,Houston Thompson R,Kwon ED,Murphy L,Riehle DL,Blute ML,Leibovich BC,Vasmatzis G,Cheville JC

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

journal_title：Cancer

authors： Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

更新日期：2002-05-15 00:00:00

abstract：:Intersitial pneumonia and pulmonary fibrosis developed in a 72-year-old man during therapy with cyclophosphamide, vincristine, and prednisone. After extensive investigations, including an open lung biopsy, cyclophosphamide appeared to be the cause of the pulmonary disease. Complete disappearance of tachypnea and the p...

journal_title：Cancer

authors： Patel AR,Shah PC,Rhee HL,Sassoon H,Rao KP

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Although breast-conserving therapy (tumor excision, axillary node dissection, and postoperative radiation) for women with breast cancer yields survival and local recurrence rates comparable with those of modified radical mastectomy, studies suggest that postoperative radiation leads to capsular contractures ...

journal_title：Cancer

authors： Guenther JM,Tokita KM,Giuliano AE

更新日期：1994-05-15 00:00:00

abstract：BACKGROUND:The objective of the current study was to assess the efficacy of combination therapy with fludarabine and mitoxantrone in patients with B-cell chronic lymphocytic leukemia (CLL). METHODS:Eighty-eight patients were treated with fludarabine 30 mg/m(2) intravenously daily for 3 days and mitoxantrone 10 mg/m(2)...

journal_title：Cancer

authors： Tsimberidou AM,Keating MJ,Giles FJ,Wierda WG,Ferrajoli A,Lerner S,Beran M,Andreeff M,Kantarjian HM,O'Brien S

更新日期：2004-06-15 00:00:00

abstract：BACKGROUND:During hospitalization for hematopoietic stem cell transplantation (HCT), patients experience a steep deterioration in quality of life (QOL) and mood. To our knowledge, the impact of this deterioration on patients' QOL and posttraumatic stress disorder (PTSD) symptoms after HCT is unknown. METHODS:We conduc...

journal_title：Cancer

authors： El-Jawahri AR,Vandusen HB,Traeger LN,Fishbein JN,Keenan T,Gallagher ER,Greer JA,Pirl WF,Jackson VA,Spitzer TR,Chen YB,Temel JS

更新日期：2016-03-01 00:00:00