Characterization of pathologic complete response after preoperative chemoradiotherapy in carcinoma of the esophagus and outcome after pathologic complete response.

abstract：BACKGROUND:Patients with hereditary leiomyomatosis and renal cell carcinoma (HLRCC) resulting from fumarate hydratase (FH) mutations may present with skin, uterine, and renal tumors, with each having unique pathologic features. This study investigated the association between prospectively identified suspicious patholog...

journal_title：Cancer

authors： Kopp RP,Stratton KL,Glogowski E,Schrader KA,Rau-Murthy R,Russo P,Coleman JA,Offit K

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Complementary medicine has become an important aspect of palliative cancer care. This overview is primarily aimed at providing guidance to clinicians regarding some commonly used complementary therapies. METHODS:Several complementary therapies were identified as particularly relevant to palliative cancer ca...

journal_title：Cancer

authors： Ernst E

更新日期：2001-06-01 00:00:00

abstract：:The cancer experience among 754 first-degree relatives (mothers, fathers, and siblings) of a population-based series of 177 children with soft tissue sarcoma is reported. The current study represents an extension of our earlier work in which the authors found an excess of breast cancer in the mothers of 143 of these c...

journal_title：Cancer

authors： Birch JM,Hartley AL,Blair V,Kelsey AM,Harris M,Teare MD,Jones PH

更新日期：1990-11-15 00:00:00

abstract：:The altered expression of the human retinoblastoma (RB) gene has been demonstrated to play an important role in the pathogenesis of RB and other tumors. To determine whether the RB gene might be involved in the pathogenesis of human ovarian and endometrial cancer, DNA from 24 human ovarian tumors, 3 normal ovaries, 3 ...

journal_title：Cancer

authors： Sasano H,Comerford J,Silverberg SG,Garrett CT

更新日期：1990-11-15 00:00:00

abstract：:The issue of how immunoglobulins are transported across the intestinal epithelium into the gut lumen was examined by immunohistocytochemical techniques. IgA, IgM, IgG and secretory component (SC) in human small intestine at light and electron microscopic levels were localized by the peroxidase-labeled antibody techniq...

journal_title：Cancer

authors： Brown WR

更新日期：1977-11-01 00:00:00

abstract：:A solitary hepatic tumor in a 50-year-old woman, which was observed as a hemangioma, ultimately was resected because it increased in size. The tumor volume doubling time was 28.8 months over the observed period of 30 months. The histologic diagnosis was carcinoid tumor. Immunohistochemical staining showed strong focal...

journal_title：Cancer

authors： Moriura S,Ikeda S,Hirai M,Naiki K,Fujioka T,Yokochi K,Gotou S

更新日期：1993-09-01 00:00:00

abstract：:The present study was carried out to investigate a distinctive type of carcinoma of the uterine cervix categorized under the designation as circumscribed carcinoma with lymphocytic infiltration. Grossly this carcinoma is characterized by defined circumscription with a superficial ulceration. A microscropic feature cha...

journal_title：Cancer

authors： Hasumi K,Sugano H,Sakamoto G,Masubuchi K,Kubo H

更新日期：1977-06-01 00:00:00

abstract：:Nine children with acute promyelocytic leukemia (APL) are presented. This series of children represents 7% of all acute leukemias and 21% of acute myelogenous leukemias seen during the same period at the Red Cross War Memorial Children's Hospital. These figures are much higher than the incidence quoted in other series...

journal_title：Cancer

authors： Gilbert RD,Karabus CD,Mills AE

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related protein (PTHrP) is the predominant cause of humoral hypercalcemia of malignancy (HHM). METHODS:Using a PTHrP-specific monoclonal antibody (MoAb), 4B3, the authors investigated the immunohistochemical localization of PTHrP in formalin-fixed and paraffin-embedded sections of normal...

journal_title：Cancer

authors： Gotoh A,Kitazawa S,Mizuno Y,Takenaka A,Arakawa S,Matsumoto O,Kitazawa R,Fujimori T,Maeda S,Kamidono S

更新日期：1993-05-01 00:00:00

abstract：:The role of hyperthermic isolation perfusion in the treatment of advanced melanoma of the limbs is clearly important. However, attention has in the past been focussed mainly on surgical aspects of the procedure. Whereas, equivalent interest in chemotherapy considerations has been lacking. A group of 15 patients have b...

journal_title：Cancer

authors： Klein ES,Ben-Ari GY

更新日期：1987-03-15 00:00:00

abstract：BACKGROUND:Workload is extensively regulated and often used as a measure of quality in gynecologic cytology. Whether workload correlates with the sensitivity of screening in gynecologic cytology is not known. METHODS:The sensitivity of gynecologic cytology screening was measured over an 8-month period using the result...

journal_title：Cancer

authors： Deschenes M,Renshaw AA,Auger M

更新日期：2008-06-25 00:00:00

abstract：:The prognostic value of nuclear DNA content was studied retrospectively using flow cytometry in 203 cases of resected hepatocellular carcinoma. The occurrence of DNA aneuploidy, which was detected in 50% of patients, correlated significantly with tumor size and the presence of vascular invasion or intrahepatic metasta...

journal_title：Cancer

authors： Fujimoto J,Okamoto E,Yamanaka N,Toyosaka A,Mitsunobu M

更新日期：1991-02-15 00:00:00

abstract：:Patients with malignant gliomas who had undergone BCG inoculation were injected intratumorally with PPD to induce an intratumoral delayed hypersensitivity reaction. Histopathological examination of the tumor before and after PPD injections revealed that chronic inflammatory responses were increased after injection in ...

journal_title：Cancer

authors： Albright L,Seab JA,Ommaya AK

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:Recent clinical trials support adding ovarian suppression (OS) to oral endocrine therapy (ET) for premenopausal women with early breast cancer. The adoption of OS among real-world populations and the impact of OS on ET adherence have not been evaluated. METHODS:This study examined a retrospective, observati...

journal_title：Cancer

authors： Reeder-Hayes KE,Mayer SE,Lund JL

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:Pegylated liposomal doxorubicin (PEG-LD) and docetaxel have single-agent activity in several malignancies. The authors conducted a Phase I trial to evaluate the maximum tolerated dose (MTD), toxicities, and effect of dose sequencing of this combination in patients with advanced malignancies. METHODS:Twenty-...

journal_title：Cancer

authors： Fracasso PM,Rodriguez LC,Herzog TJ,Fears CL,Goodner SA,Govindan R,Picus J,Rader JS,Tan BR,Arquette MA

更新日期：2003-08-01 00:00:00

abstract：:Androgen deprivation therapy (ADT) is now a well-established standard of care in combination with definitive radiotherapy for patients with unfavorable intermediate-risk to high-risk locally advanced prostate cancer. It is also well established that combination modality treatment with ADT and radiotherapy is superior ...

journal_title：Cancer

authors： Roach M 3rd

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Atypia of undetermined significance is a controversial category in thyroid fine-needle aspiration (FNA), not only for its questioned clinical utility, but also for its very existence as an expression of uncertainty. The current study was performed to investigate the potential impact of eliminating this categ...

journal_title：Cancer

authors： Shi Y,Ding X,Klein M,Sugrue C,Matano S,Edelman M,Wasserman P

更新日期：2009-10-25 00:00:00

abstract：:Results from the standpoint of survival rates and locoregional failures are compared in three series of patients having had a radical mastectomy for breast cancer: (1) radical mastectomy alone for the patients who had essentially outer quadrant lesions and a negative axilla; (2) postoperative irradiation when the axil...

journal_title：Cancer

authors： Rodger A,Montague ED,Fletcher G

更新日期：1983-04-15 00:00:00

abstract：:Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...

journal_title：Cancer

authors： Marks LB

更新日期：1990-12-15 00:00:00

abstract：:A 42-year-old woman developed lower extremity weakness and sensory loss 1 year after external and intracavitary radiotherapy for Stage IB carcinoma of cervix. She has been followed for 5 years posttreatment, and the neurologic abnormalities have persisted, but no evidence of recurrent carcinoma has been found. We beli...

journal_title：Cancer

authors： Stryker JA,Sommerville K,Perez R,Velkley DE

更新日期：1990-10-01 00:00:00

abstract：:The National Comprehensive Cancer Network (NCCN) describes the presence of extracapsular spread and/or positive margins in oropharynx cancer (OPC) as an indication for the addition of chemotherapy to postoperative radiation. The guideline's category 1 consensus is based on what they term high-level evidence. For this ...

journal_title：Cancer

authors： Sinha P,Piccirillo JF,Kallogjeri D,Spitznagel EL,Haughey BH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Despite improvements in survival rates, cancer treatments have significant side effects that affect the quality of life of children and their families. When an ill child cannot self-report symptoms (eg, he or she is too ill), caregiver (parent) reporting becomes critical. This study evaluates the validity an...

journal_title：Cancer

authors： Reeve BB,McFatrich M,Lin L,Lucas NR,Mack JW,Jacobs SS,Withycombe JS,Baker JN,Freyer DR,Hinds PS

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:Examination was performed on pathologic material from patients enrolled in the National Surgical Adjuvant Breast Project (NSABP) protocol B-18, in which the clinical effects of preoperative (preop) and postoperative (postop) doxorubicin and cyclophosphamide (AC) were compared. METHODS:Of the total number of...

journal_title：Cancer

authors： Fisher ER,Wang J,Bryant J,Fisher B,Mamounas E,Wolmark N

更新日期：2002-08-15 00:00:00

abstract：BACKGROUND:The therapeutic impact of tumor resection is poorly defined. Therefore the current study was conducted. METHODS:A retrospective, 2-institutional study was conducted (1991-1994) to compare the treatment results of stereotactic biopsy plus radiation therapy (99 patients; tumor dose: 60 gray [Gy]) with those o...

journal_title：Cancer

authors： Kreth FW,Berlis A,Spiropoulou V,Faist M,Scheremet R,Rossner R,Volk B,Ostertag CB

更新日期：1999-11-15 00:00:00

abstract：:Congenital self-healing histiocytosis (CSHH) is a rare primary histiocytic skin disorder. Only a few cases have been studied by ultrastructure and immunohistochemistry. Here we report a new case that was investigated using an electron microscope and a panel of monoclonal (MCA) and polyclonal (PCA) antibodies. CSHH cel...

journal_title：Cancer

authors： Kanitakis J,Zambruno G,Schmitt D,Cambazard F,Jacquemier D,Thivolet J

更新日期：1988-02-01 00:00:00

abstract：:The descriptive epidemiologic features of bladder cancer and lung cancer in Los Angeles County were studied for the period 1972-1976, using data from the Los Angeles County/University of Southern California Cancer Surveillance Program. The incidence pattern for bladder cancer was found to differ markedly from the patt...

journal_title：Cancer

authors： Weinberg DM,Ross RK,Mack TM,Paganini-Hill A,Henderson BE

更新日期：1983-02-15 00:00:00

abstract：:A case of a hemangiopericytoma tumor metastatic to the lung from a central nervous system primary tumor in the posterior fossa is reported. The tumor was not responsive to treatment with cyclophosphamide, Adriamycin (doxorubicin), vincristine, DTIC (CYVADIC), high-dose methotrexate with citrovorum factor rescue, aziri...

journal_title：Cancer

authors： Hart LL,Weinberg JB

更新日期：1987-08-15 00:00:00

abstract：BACKGROUND:Epidemiologic studies have recently related benzene hexachloride (BHC) to breast carcinoma risk. Experimental studies have also shown that beta-BHC is weakly estrogenic, hence supporting the alleged association. By directly comparing beta-BHC levels in breast adipose tissue from incident breast carcinoma cas...

journal_title：Cancer

authors： Zheng T,Holford TR,Mayne ST,Owens PH,Ward B,Carter D,Dubrow R,Zahm SH,Boyle P,Tessari J

更新日期：1999-05-15 00:00:00

abstract：BACKGROUND:Prostate-specific antigen (PSA) screening for prostate cancer has high risks of overdiagnosis, particularly among older men, and reports from screening trials indicate that it saves few lives after 11 to 13 years of follow-up. New clinical guidelines recommend against PSA screening for all men or for men age...

journal_title：Cancer

authors： Gulati R,Tsodikov A,Etzioni R,Hunter-Merrill RA,Gore JL,Mariotto AB,Cooperberg MR

更新日期：2014-11-15 00:00:00

abstract：BACKGROUND:A review of the literature indicated variable underestimation rates for breast core-needle biopsy (CNB) based on generally small series. In this article, the authors present precise estimates for overall underestimation and for categories of histologic underestimates (including categories that reflect contem...

journal_title：Cancer

authors： Houssami N,Ciatto S,Ellis I,Ambrogetti D

更新日期：2007-02-01 00:00:00