Acute promyelocytic leukemia. A childhood cluster.

abstract：BACKGROUND:Recently, the authors identified molecular signatures and pathways associated with nonsmall cell lung carcinoma histology and lung development. They hypothesized that genetic classifiers of histology would provide insight into lung tumorigenesis and would be associated with clinical outcome when evaluated in...

journal_title：Cancer

authors： Shah L,Walter KL,Borczuk AC,Kawut SM,Sonett JR,Gorenstein LA,Ginsburg ME,Steinglass KM,Powell CA

更新日期：2004-10-01 00:00:00

abstract：:The potential of using a blood test enumerating oncofetal ferritin-bearing lymphocytes (FBL) as a biomarker for early breast cancer was further explored. Nine hundred women attending a high-risk breast cancer clinic and 2500 normal-risk women were physically examined and their blood drawn for FBL determination using a...

journal_title：Cancer

authors： Moroz C,Kahn M,Ron E,Luria H,Chaimoff C

更新日期：1989-08-01 00:00:00

abstract：:The kinetics of initial arrest in organs, distribution, survival, and fate of 125I-iododeoxyuridine-labeled B16 melanoma tumor cells injected intravenously into normal, tumor-sensitized and immune manipulated syngeneic and allogeneic mice were investigated. Groups of animals were killed at intervals ranging from two m...

journal_title：Cancer

authors： Fidler IJ,Gersten DM,Riggs CW

更新日期：1977-07-01 00:00:00

abstract：:Nickel-related cancers of the respiratory tract have been recognized for nearly 50 years and represent a unique opportunity for prevention among refinery workers. Studies of exposed employees have been conducted in which evaluations were made of the histopathologic changes in the respiratory mucosa and the body burden...

journal_title：Cancer

authors： Barton RT,Hogetveit AC

更新日期：1980-06-15 00:00:00

abstract：BACKGROUND:A randomized, multicenter trial, double-blind for antiandrogen therapy, compared the antiandrogens bicalutamide and flutamide, each combined with luteinizing hormone-releasing hormone analogue therapy (LHRH-A) in 813 patients with Stage D2 prostate carcinoma. An analysis of time to progression (median follow...

journal_title：Cancer

authors： Schellhammer PF,Sharifi R,Block NL,Soloway MS,Venner PM,Patterson AL,Sarosdy MF,Vogelzang NJ,Chen Y,Kolvenbag GJ

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:Previous biochemotherapy regimens for metastatic melanoma have required attenuated dosages of interleukin 2 (IL-2) that may have compromised efficacy. METHODS:In a phase 2 study, the authors tested sequential temozolomide (75 mg/m2 per day orally for 3 weeks) followed by high-dose, IL-2 (600,000 U/kg per do...

journal_title：Cancer

authors： Tarhini AA,Kirkwood JM,Gooding WE,Moschos S,Agarwala SS

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:To retrospectively evaluate the significance of morphologic examination and ancillary studies performed on bilateral bone marrow biopsy specimens, 1864 bone marrow samples were studied. METHODS:Bilateral bone marrow biopsy specimens included 883 specimens that were evaluated for involvement by non-Hodgkin l...

journal_title：Cancer

authors： Wang J,Weiss LM,Chang KL,Slovak ML,Gaal K,Forman SJ,Arber DA

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The carboplatin-based chemotherapeutic regimen M-CAVI (methotrexate, carboplatin, and vinblastine) is active against bladder carcinoma and can be administered to patients who are ineligible to receive cisplatin or doxorubicin. The authors designed a randomized study to evaluate whether M-CAVI offers a therap...

journal_title：Cancer

authors： Bellmunt J,Ribas A,Eres N,Albanell J,Almanza C,Bermejo B,Solé LA,Baselga J

更新日期：1997-11-15 00:00:00

abstract：:A system for staging the clinical status of patients with soft tissue sarcomas is presented, based on the clinical characteristics of the primary tumor (size, extension), the involvement of lymph nodes, the presence of metastases, and the grade of the tumor. This represents the TNM system with grade of tumor (G) added...

journal_title：Cancer

authors： Russell WO,Cohen J,Enzinger F,Hajdu SI,Heise H,Martin RG,Meissner W,Miller WT,Schmitz RL,Suit HD

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:The hepatitis activity index (HAI) score describes the histologic status of accompanying chronic hepatitis and was established by pathologists. The aim of this study was twofold: 1) to investigate the correlation between intrahepatic metastatic recurrence (IM) and the HAI score of the noncancerous region of ...

journal_title：Cancer

authors： Ueno S,Tanabe G,Yoshida A,Yoshidome S,Takao S,Aikou T

更新日期：1999-07-15 00:00:00

abstract：BACKGROUND:Forty patients with Stage II-III breast cancer with 10 or more positive axillary nodes were treated with mastectomy followed by four cycles of standard dose CAF (cytoxan, Adriamycin, 5-FU), followed by high dose cytoxan, cisplatin, carmustine (HDCT) with autologous bone marrow transplant support (ABMT), and ...

journal_title：Cancer

authors： Marks LB,Rosner GL,Prosnitz LR,Ross M,Vredenburgh JJ,Peters WP

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Clear cell sarcoma (CCS) of tendons and aponeuroses is extremely rare in childhood and little information is available on its clinical management. Originally believed to be a type of melanoma of soft tissue origin, CCS is now considered a distinct clinicopathologic entity that behaves like a high-grade soft ...

journal_title：Cancer

authors： Ferrari A,Casanova M,Bisogno G,Mattke A,Meazza C,Gandola L,Sotti G,Cecchetto G,Harms D,Koscielniak E,Treuner J,Carli M

更新日期：2002-06-15 00:00:00

abstract：:An unusually high association of other primary cancers (9.7%) was found during the analysis of 403 consecutive cases of carcinoma of the lung diagnosed at DGMC between 1960 and 1975. Incidence by stage included 17.3% for Stage I (75 cases) and 16.9% for Stage II (59 cases). Median survival by stage was not adversely a...

journal_title：Cancer

authors： Reynolds RD,Pajak TF,Greenberg BR,Shirley JH,Lucas RN,Hill RP,Schacht LR

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:An estimated 5-10% of all pancreatic adenocarcinomas have a hereditary association. The objective of the current study was to characterize the clinical and pathologic features of familial pancreatic carcinoma and to determine potential differences in demographics, risk factors, and outcomes between familial ...

journal_title：Cancer

authors： James TA,Sheldon DG,Rajput A,Kuvshinoff BW,Javle MM,Nava HR,Smith JL,Gibbs JF

更新日期：2004-12-15 00:00:00

abstract：:Carcinomas of the pancreas with giant cells are not rare, but those containing osteoclast-like tumor cells are quite unusual. This report documents a pancreatic neoplasm comprising both easily recognizable well-differentiated adenocarcinoma and osteoclast-like tumor. The literature on the "osteoclastoma" of the pancre...

journal_title：Cancer

authors： Trepeta RW,Mathur B,Lagin S,LiVolsi VA

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Over the past 2 decades, significant progress has been made in the field of metastatic colorectal cancer (mCRC) regarding new imaging techniques, surgical interventions, and systemic therapy. It is not known whether the benefit from these interventions has extended overall survival (OS) within the general mC...

journal_title：Cancer

authors： Golan T,Urban D,Berger R,Lawrence YR

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:Telomerase is an enzyme that can reconstitute the ends (telomeres) of chromosomes after cell division and thus circumvent the cumulative damage that occurs in normal adult somatic cells during successive mitotic cycles. Recently, it has been proposed that this enzyme should, therefore, be detectable in immor...

journal_title：Cancer

authors： Yoshida K,Sugino T,Tahara H,Woodman A,Bolodeoku J,Nargund V,Fellows G,Goodison S,Tahara E,Tarin D

更新日期：1997-01-15 00:00:00

abstract：:Using a silver staining technique, nucleolar organizer region-associated proteins (Ag-NOR) were studied in paraffin sections of five specimens of normal bronchial epithelium, eight of atypical squamous metaplasia, five of carcinoma in situ, and seven of microinvasive squamous cell carcinoma. The mean number of Ag-NOR ...

journal_title：Cancer

authors： Abe S,Ogura S,Kunikane H,Suko N,Watanabe N,Nakajima I,Kawakami Y,Inoue K

更新日期：1991-01-15 00:00:00

abstract：:The breast pathology files at the Institut Gustave-Russy in Villejuif, France, were searched for papillary cystadenomas and papillary carcinomas diagnosed between January 1, 1960, and December 31, 1974. A total of 158 cases were selected for this study; they were subclassified into 74 papillary cystadenomas, 63 papill...

journal_title：Cancer

authors： Murad TM,Contesso G,Mouriesse H

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:Approximately 5-10% of patients with rhabdomyosarcomas (RMS) are diagnosed during the first year of life, and their clinical characteristics have been well documented. However, because RMS rarely occurs during the neonatal period, little is known about neonatal RMS. METHODS:Four patients with neonatal RMS w...

journal_title：Cancer

authors： Rodriguez-Galindo C,Hill DA,Onyekwere O,Pin N,Rao BN,Hoffer FA,Kun LE,Pappo AS,Santana VM

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:Several pathologic staging systems for malignant pleural mesothelioma (MPM) have been published, but none of them provide optimal survival stratification or stage distribution among patients treated with surgery. Interpretation of prior studies that correlate pathologic factors with outcome has been confound...

journal_title：Cancer

authors： Richards WG,Godleski JJ,Yeap BY,Corson JM,Chirieac LR,Zellos L,Mujoomdar A,Jaklitsch MT,Bueno R,Sugarbaker DJ

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:The role of adjuvant therapy in the management of patients with malignant mixed Müllerian tumors (MMMT) of the uterus has not been defined. The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed. METHODS:A pilot study was performed on 38 patients with clinic...

journal_title：Cancer

authors： Manolitsas TP,Wain GV,Williams KE,Freidlander M,Hacker NF

更新日期：2001-04-15 00:00:00

abstract：:The objective of this study was to evaluate the sensitivity of two methods for determining bone marrow involvement with non-Hodgkin's lymphoma. These methods were histologic review of bone marrow aspirates, and clot sections versus in vitro growth of lymphoma colonies on soft agar. Forty-two bone marrow aspirates were...

journal_title：Cancer

authors： Smith SD,Kisker S,Bush L,Trueworthy RC

更新日期：1984-04-15 00:00:00

abstract：:The authors discovered some errors regarding reference group labels in Table 2. The corrected table is attached. The authors regret these errors. ...

journal_title：Cancer

authors：

更新日期：2015-03-01 00:00:00

abstract：:Although improvements in the management of adults with acute leukemia have lagged behind those seen in the treatment of children, there are clear reasons for optimism. Combination chemotherapy for acute myeloblastic leukemia (AML) and acute lymphoblastic leukemia (ALL) in adults results in complete remissions in 50-85...

journal_title：Cancer

authors： Eyre HJ,Ward JH,Priebat DA

更新日期：1983-06-15 00:00:00

abstract：:True adenomas of the breast are cellular epithelial lesions, which may be confused with carcinoma and are difficult to classify. We have reviewed 28 adenomas of the breast and have developed specific diagnostic criteria, as well as a classification of breast adenomas based on histologic features. Electron microscopic ...

journal_title：Cancer

authors： Hertel BF,Zaloudek C,Kempson RL

更新日期：1976-06-01 00:00:00

abstract：:The cancer experience among 754 first-degree relatives (mothers, fathers, and siblings) of a population-based series of 177 children with soft tissue sarcoma is reported. The current study represents an extension of our earlier work in which the authors found an excess of breast cancer in the mothers of 143 of these c...

journal_title：Cancer

authors： Birch JM,Hartley AL,Blair V,Kelsey AM,Harris M,Teare MD,Jones PH

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:The vast majority of soft tissue sarcomas spread initially to the lungs and then to other sites. The lung has been the most carefully monitored organ system during routine surveillance for a metastasis. Liposarcoma is one of the most common soft tissue sarcomas and has been noted to have extrapulmonary sites...

journal_title：Cancer

authors： Cheng EY,Springfield DS,Mankin HJ

更新日期：1995-03-01 00:00:00

abstract：:Compliance in oncology clinic attendance was prospectively evaluated over a 12-month period at Harlem Hospital Center, an inner city municipal facility serving a predominantly black population. One hundred patients were followed (97 blacks, 2 Hispanics, 1 white) with an average age of 60 years. There were 41 men and 5...

journal_title：Cancer

authors： Garrett TJ,Ashford A,Savage DG

更新日期：1986-08-01 00:00:00

abstract：:Indomethacin (prostaglandin synthetase inhibitor) was found to be capable of enhancing the mitogen-induced lymphocyte proliferative responses of healthy subjects and patients with lung cancer. A whole-blood culture technique was used. Indomethacin had no mitogenic activity. We observed a greater enhancement of lymphoc...

journal_title：Cancer

authors： Han T,Takita H

更新日期：1980-12-01 00:00:00