Relationship of host immune status to tumor cell arrest, distribution, and survival in experimental metastasis.

abstract：:In a 10-year incidence survey of breast cancer in the City of Boston, 14 cases in American Chinese women were observed, while approximately 13 were expected on the basis of age-specific incidence in the white population. In Hawaii, on the other hand, while breast cancer incidence rates for ethnic Chinese are approxima...

journal_title：Cancer

authors： Trichopoulos D,Yen S,Brown J,Cole P,MacMahon B

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Uveal melanomas of the choroid and ciliary body are aggressive tumors causing the death of approximately 50% of patients. In contrast, iris melanomas only infrequently metastasize; why these differences exist is not known. The local environment can regulate cancer growth and development, and it is probable t...

journal_title：Cancer

authors： Canovas D,Rennie IG,Nichols CE,Sisley K

更新日期：2008-04-15 00:00:00

abstract：BACKGROUND:Poor accrual to cancer clinical trials may contribute to the lower improvement in survival observed for adolescents and young adults (AYAs) (those aged 15-39 years) with cancer. This has been difficult to quantify without reliable mechanisms to link incident cases with study enrollments. Using unique resourc...

journal_title：Cancer

authors： Collins CL,Malvar J,Hamilton AS,Deapen DM,Freyer DR

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Testicular cancer is curable in the majority of men, and persisting treatment toxicity is a concern. The authors report a cross-sectional study of the long-term effects of chemotherapy (C) on neurologic function and development of Raynaud phenomenon. METHODS:Seven hundred thirty-nine patients who were treat...

journal_title：Cancer

authors： Glendenning JL,Barbachano Y,Norman AR,Dearnaley DP,Horwich A,Huddart RA

更新日期：2010-05-15 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related protein (PTHrP) is the predominant cause of humoral hypercalcemia of malignancy (HHM). METHODS:Using a PTHrP-specific monoclonal antibody (MoAb), 4B3, the authors investigated the immunohistochemical localization of PTHrP in formalin-fixed and paraffin-embedded sections of normal...

journal_title：Cancer

authors： Gotoh A,Kitazawa S,Mizuno Y,Takenaka A,Arakawa S,Matsumoto O,Kitazawa R,Fujimori T,Maeda S,Kamidono S

更新日期：1993-05-01 00:00:00

abstract：:Jaundice and hepatomegaly developed in a boy with Fanconi anemia after he had undergone treatment with oxymetholone for nine years. A liver scan showed patchy uptake consistent with the presence of space-occupying lesions. After oxymetholone treatment was stopped, the jaundice resolved, the liver size decreased, and t...

journal_title：Cancer

authors： Obeid DA,Hill FG,Harnden D,Mann JR,Wood BS

更新日期：1980-09-15 00:00:00

abstract：BACKGROUND:Patients with advanced cancer often experience fatigue and other symptoms that negatively impact their quality of life. The current trial investigated the effect of melatonin on fatigue and other symptoms in patients with advanced cancer. METHODS:Patients who were aged ≥18 years, had a histologically confir...

journal_title：Cancer

authors： Lund Rasmussen C,Klee Olsen M,Thit Johnsen A,Petersen MA,Lindholm H,Andersen L,Villadsen B,Groenvold M,Pedersen L

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:Patients with advanced soft tissue sarcomas (STS) have limited therapeutic options. Sorafenib (BAY 43-9006) is a multitargeted tyrosine kinase inhibitor of raf, vascular endothelial growth factor receptors 1 (VEGFR1) through 3, platelet-derived growth factor B, fms-like tyrosine kinase 3, and c-kit, and some...

journal_title：Cancer

authors： von Mehren M,Rankin C,Goldblum JR,Demetri GD,Bramwell V,Ryan CW,Borden E

更新日期：2012-02-01 00:00:00

abstract：:In order to determine whether the use of a sequence of chemotherapeutic regimens plus BCG could produce longer durations of remission in adult acute nonlymphocytic leukemia than maintenance therapy with cytosine arabinoside, 6-thioguanine, plus BCG, a randomized study was performed at Washington University. Upon achie...

journal_title：Cancer

authors： Presant CA,Berger NA,Klahr C,Phillips GL

更新日期：1980-07-01 00:00:00

abstract：:From November 1973 to May 1986, 50 patients with Stage I epithelial ovarian cancer were treated at the University of Kentucky Medical Center (Lexington, KY) with oral Alkeran (melphalan) chemotherapy after primary surgery. Twenty-two patients had Grade 1 tumors, 23 patients had Grade 2 tumors, and five patients had Gr...

journal_title：Cancer

authors： Gallion HH,van Nagell JR,Donaldson ES,Higgins RV,Powell DE,Kryscio RJ

更新日期：1989-03-15 00:00:00

abstract：:The records of 1,497 patients with histologically proven adenocarcinoma of the stomach were reviewed from Charity Hospital over the 25-year period, 1948 to 1973. The operability rate was 82% and the resectability rate was 48%. In this series gastric carcinoma predominated in males and Negroes. Necropsy studies indicat...

journal_title：Cancer

authors： Dupont JB Jr,Lee JR,Burton GR,Cohn I Jr

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Many experienced oncologists have encountered patients with proven non-small cell lung cancer (NCLC) who received modest doses of palliative radiotherapy (RT) and who unexpectedly survived for > 5 years; some were apparently cured. We used a very large prospective database to estimate the frequency of this p...

journal_title：Cancer

authors： Mac Manus MP,Matthews JP,Wada M,Wirth A,Worotniuk V,Ball DL

更新日期：2006-03-01 00:00:00

abstract：:The autopsies of 80 patients with Hodgkin's disease (HD) were reviewed. Nearly one-third of the patients died without evidence of HD at autopsy. Four patients died with clinically unsuspected HD. Infection was the most common cause of death but a significant number of patients died of complications of therapy, both be...

journal_title：Cancer

authors： Colby TV,Hoppe RT,Warnke RA

更新日期：1981-04-01 00:00:00

abstract：:The records of 314 children with acute lymphocytic leukemia (ALL) were reviewed to determine the frequency, clinical and laboratory features; contributing factors; and prognosis of cyclophosphamide-induced hemorrhagic cystitis. Twenty-five well-documented cases of hemorrhagic cystitis were identified. While most of th...

journal_title：Cancer

authors： Lawrence HJ,Simone J,Aur RJ

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Preoperative chemotherapy for hepatic resection of colorectal liver metastases is associated with the development of chemotherapy-associated steatohepatitis (CASH). This increases the risk of perioperative morbidity and mortality. To the authors' knowledge, an animal model for CASH has not been described pre...

journal_title：Cancer

authors： Keizman D,Maimon N,Ish-Shalom M,Buchbut D,Inbar M,Klein B,Bernheim J,Goldiner I,Leikin-Frenkel A,Konikoff F

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Conditional survival is clinically useful, particularly for patients with malignant disease who have a poor prognosis. However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis. METHODS:Data on 217,573 patients with breast, colorectal, ...

journal_title：Cancer

authors： Kato I,Severson RK,Schwartz AG

更新日期：2001-10-15 00:00:00

abstract：BACKGROUND:This study assessed the impact of surgical, histopathologic and patient-related factors on the risks of local and distant recurrence and overall survival for patients with stages I through IIIA nonsmall cell lung carcinoma (NSCLC) undergoing definitive resection with or without adjuvant chemotherapy. METHOD...

journal_title：Cancer

authors： Varlotto JM,Recht A,Flickinger JC,Medford-Davis LN,Dyer AM,Decamp MM

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The Univ...

journal_title：Cancer

authors： Brusco LL,Wathoo C,Mills Shaw KR,Holla VR,Bailey AM,Johnson AM,Khotskaya YB,Litzenburger BC,Sanchez NS,Zeng J,Bernstam EV,Eng C,Kee BK,Amaria RN,Routbort MJ,Mills GB,Mendelsohn J,Meric-Bernstam F

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Excessive risk of cutaneous melanoma as a second cancer has been associated with benign or malignant tumors of the nervous system. Cutaneous melanoma and nervous system tumors may independently aggregate in families. There are, however, no previous reports of increased likelihood of tumors of the nervous sys...

journal_title：Cancer

authors： Azizi E,Friedman J,Pavlotsky F,Iscovich J,Bornstein A,Shafir R,Trau H,Brenner H,Nass D

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Podoplanin is a mucin-like glycoprotein that is important in lymphangiogenesis but not blood vessel formation. Recent studies suggested a potential role of podoplanin in certain tumor cells. The purpose of the current study was to determine the role of podoplanin in head and neck squamous cell carcinoma (HNS...

journal_title：Cancer

authors： Yuan P,Temam S,El-Naggar A,Zhou X,Liu DD,Lee JJ,Mao L

更新日期：2006-08-01 00:00:00

abstract：:The administration of two chemoimmunotherapy programs to 103 consecutive patients with metastatic colorectal cancer resulted in improved survival for patients who achieved either objective tumor regressions or disease stabilization for more than 8 weeks. Objective tumor regression was observed in 47% of patients treat...

journal_title：Cancer

authors： Valdivieso M,Bedikian A,Burgess MA,Rodriguez V,Hersh EM,Bodey GP,Mavligit GM

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Surgery alone is the appropriate first-line treatment for patients with mesoblastic nephroma (MN). Nevertheless, there are reports of local recurrences and metastasis, especially in the cellular subtype. The authors evaluated the outcome of patients with MN who were enrolled in either the International Socie...

journal_title：Cancer

authors： Furtwaengler R,Reinhard H,Leuschner I,Schenk JP,Goebel U,Claviez A,Kulozik A,Zoubek A,von Schweinitz D,Graf N,Gesellschaft fur Pädiatrische Onkologie und Hämatologie (GPOH) Nephroblastoma Study Group.

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:Recently, adenomatous hyperplasia (AH) of the liver, a sizable parenchymal nodule in the cirrhotic liver, has been considered a preneoplastic lesion in human hepatocarcinogenesis. METHODS:The authors evaluated cell proliferative activity by immunostaining for proliferating cell nuclear antigen (PCNA) in AH ...

journal_title：Cancer

authors： Terada T,Nakanuma Y

更新日期：1992-08-01 00:00:00

abstract：:Esophageal prothesis (EP) is a palliative treatment for inoperable neoplastic stenosis. Ninety-one patients were candidates for EP placement between 1978 and 1983. EP placement was successful in 77 patients. Of these: 85% had primary esophageal cancer; 15% had bronchial or mediastinal carcinoma; 83% had stenosis in th...

journal_title：Cancer

authors： Chavy AL,Rougier M,Pieddeloup C,Kac J,Laplanche AC,Elias DM,Ducreux MP,Zummer-Rubinstein K,Zimmermann PA,Charbit MA

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:The current study was designed to evaluate the efficacy and toxicity of the continuous oral administration of a combination of cyclophosphamide (50 mg/day given in the morning) and dexamethasone (1 mg/day given in the evening) in patients with prostate specific antigen (PSA) progression despite single or mul...

journal_title：Cancer

authors： Glode LM,Barqawi A,Crighton F,Crawford ED,Kerbel R

更新日期：2003-10-15 00:00:00

abstract：:As part of epidemiologic studies of human T-lymphotropic virus (HTLV)-I-associated malignancies in Jamaica, the authors evaluated 26 patients with non-Hodgkin's lymphoma for the presence of integrated HTLV-I provirus in their malignant cells. Fifteen of 26 patients had integrated provirus. All 15 also were HTLV-I anti...

journal_title：Cancer

authors： Clark JW,Gurgo C,Franchini G,Gibbs WN,Lofters W,Neuland C,Mann D,Saxinger C,Gallo RC,Blattner WA

更新日期：1988-04-01 00:00:00

abstract：:Two consecutive trials for the treatment of childhood non-Hodgkin's lymphoma were evaluated, carried out by the same cooperative groups. Group A: From June, 1973 to December, 1975, 50 evaluable patients under 16 years of age participated in a study that included vincristine and prednisone plus surgery and/or radiother...

journal_title：Cancer

authors： Sackmann-Muriel F,Diez B,Schvartzman E,Braier JL,Schwartz L,Gallo G,Pavlovsky S

更新日期：1984-12-15 00:00:00

abstract：:Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...

journal_title：Cancer

authors： Marks LB

更新日期：1990-12-15 00:00:00

abstract：:During the past decade, one of the major changes in the field of oncology has been in the surgical approach to primary and secondary cancer of the liver. As a result of data and experience gained in liver transplantation programs and with the application of vascular surgical principles, resectability rates have been i...

journal_title：Cancer

authors： Fortner JG,MacLean BJ,Kim DK,Howland WS,Turnbull AD,Goldiner P,Carlon G,Beattie EJ Jr

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:The Fuhrman grading system is an established predictor of survival in patients with renal cell carcinoma (RCC). The predictive accuracy of various Fuhrman grading schemes was tested with the intent of improving the prediction of RCC-specific survival (RCC-SS). METHODS:The analyses targeted 5453 patients fro...

journal_title：Cancer

authors： Rioux-Leclercq N,Karakiewicz PI,Trinh QD,Ficarra V,Cindolo L,de la Taille A,Tostain J,Zigeuner R,Mejean A,Patard JJ

更新日期：2007-03-01 00:00:00