Fanconi anemia. Oxymetholone hepatic tumors, and chromosome aberrations associated with leukemic transition.

abstract：:A case is reported of a patient with pancreatic carcinoma who developed pancreatic ascites after intraoperative fine-needle aspiration cytology (FNAC) biopsy. This complication of FNAC has not previously been reported to the authors' knowledge. The literature is reviewed, and FNAC is shown to be the safest method of p...

journal_title：Cancer

authors： Rosenbaum DA,Frost DB

更新日期：1990-06-01 00:00:00

abstract：:Five hundred forty three adult patients with acute leukemia were entered on the study designed to: (1) test efficacy of vincristine and prednisone used as primary drug therapy in patients with good prognosis as judged by a circulating blast cell count less than 30,000 cm2; (2) investigate the use of either simultaneou...

journal_title：Cancer

authors： McCredie KB,Gehan EA,Freireich EJ,Hewlett JS,Coltman CA Jr,Hussein KK,Balcerzak SP,Chen TT

更新日期：1983-09-15 00:00:00

abstract：BACKGROUND:Validation of the prognostic indices for the recurrence-free interval of patients with parotid carcinoma, the development of which was described in a previous report, is needed to be confident of their generalizability and justified prospective use. METHODS:The Dutch Cooperative Group on Head and Neck Cance...

journal_title：Cancer

authors： Vander Poorten VL,Hart AA,van der Laan BF,Baatenburg de Jong RJ,Manni JJ,Marres HA,Meeuwis CA,Lubsen H,Terhaard CH,Balm AJ

更新日期：2003-03-15 00:00:00

abstract：:The development of drug resistance limits the survival or patients with small cell anaplastic carcinoma of the lung (SCLC). The present study was undertaken to overcome this problem by administering two alternating noncross resistant combination chemotherapy regimens. One-hundred-one patients were entered on study, an...

journal_title：Cancer

authors： Aroney RS,Bell DR,Chan WK,Dalley DN,Levi JA

更新日期：1982-06-15 00:00:00

abstract：BACKGROUND:The current study was performed to describe frequencies and risk factors of altered oral health and odontogenesis in childhood cancer survivors. METHODS:In total, 9308 survivors who were diagnosed between 1970 and 1986 and 2951 siblings from the Childhood Cancer Survivor Study completed a survey that contai...

journal_title：Cancer

authors： Kaste SC,Goodman P,Leisenring W,Stovall M,Hayashi RJ,Yeazel M,Beiraghi S,Hudson MM,Sklar CA,Robison LL,Baker KS

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:This randomized pilot trial investigated whether primary chemotherapy was feasible in terms of efficacy, survival, toxicity profile, and quality of life compared with whole-brain radiotherapy (WBRT) given first in chemotherapy-naive patients nonsmall cell lung cancer (NSCLC) with synchronous brain metastasis...

journal_title：Cancer

authors： Lee DH,Han JY,Kim HT,Yoon SJ,Pyo HR,Cho KH,Shin SH,Yoo H,Lee SH,Lee JS

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:The authors tested a biotherapy regimen involving recombinant interferon-alpha-2a (rIFN-alpha-2a) and recombinant human interleukin-2 (rhIL-2), given in a "decrescendo" schedule over 5 days, for its activity and toxicity in 21 patients who previously had received chemotherapy for advanced melanoma. METHODS:...

journal_title：Cancer

authors： Eton O,Buzaid AC,Bedikian AY,Smith TM,Papadopoulos NE,Ellerhorst JA,Hibberts JL,Legha SS,Benjamin RS

更新日期：2000-04-01 00:00:00

abstract：:A case-referent study on soft tissue sarcomas (STS) was conducted, to see if previous findings regarding an association between exposure to phenoxyacetic acids or chlorophenols and this tumor type could be reproduced. Fifty-five male STS patients were thereby compared with 220 living and 110 dead population-based refe...

journal_title：Cancer

authors： Hardell L,Eriksson M

更新日期：1988-08-01 00:00:00

abstract：:Pain management often is difficult in patients with bone metastases. Metastatic disease represents >40% of oncologic practice, and >70% of patients with metastatic disease have uncontrolled cancer-related pain. Significant morbidity caused by pathologic fracture and spinal cord compression can result from untreated bo...

journal_title：Cancer

authors： Janjan NA

更新日期：1997-10-15 00:00:00

abstract：:From November 1987 to April 1989, 1000 women 40 years or older underwent screening vaginal sonography at the University of Kentucky Medical Center (Lexington, KY). Patients included in this investigation were all asymptomatic and had no known pelvic abnormalities. Each ovary was measured in three planes and ovarian vo...

journal_title：Cancer

authors： van Nagell JR Jr,Higgins RV,Donaldson ES,Gallion HH,Powell DE,Pavlik EJ,Woods CH,Thompson EA

更新日期：1990-02-01 00:00:00

abstract：:The effect of immunotherapy with Nocardia rubra cell-wall skeleton (N-CWS) on remission duration and survival of adults with acute myelogenous leukemia (AML) was studied in a prospective randomized controlled study. After having been induced into complete remission and having been consolidated, 73 patients were random...

journal_title：Cancer

authors： Ohno R,Nakamura H,Kodera Y,Ezaki K,Yokomaku S,Oguma S,Kubota Y,Shibata H,Ogawa N,Masaoka T

更新日期：1986-04-15 00:00:00

abstract：:Prostatic intra-epithelial neoplasia (PIN, or intraductal dysplasia) is considered a precursor of invasive carcinoma, characterized by proliferation and anaplasia of cells lining prostatic ducts and acini. The highest grade of PIN, Grade 3, is thought to represent carcinoma in situ. To quantitate the degree of disrupt...

journal_title：Cancer

authors： Bostwick DG,Brawer MK

更新日期：1987-02-15 00:00:00

abstract：:We measured des-gamma-carboxyglutamic acid prothrombin (protein induced by vitamin K absence or antagonist-Factor II: [PIVKA-II]) in plasmas of normal subjects, patients with thrombotic disease, those with hepatic disease including hepatocellular carcinoma, and those with carcinoma of other tissues, and compared the r...

journal_title：Cancer

authors： Deyashiki Y,Nishioka Y,Takahashi K,Kosaka Y,Suzuki K

更新日期：1989-12-15 00:00:00

abstract：BACKGROUND:The results of an international, multicenter, randomized, double-blind, controlled study assessing the efficacy and safety of lenalidomide treatment in patients with refractory stage IV metastatic malignant melanoma are reported. METHODS:The study compared treatment with lenalidomide (25 mg/d on Days 1-21 o...

journal_title：Cancer

authors： Eisen T,Trefzer U,Hamilton A,Hersey P,Millward M,Knight RD,Jungnelius JU,Glaspy J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Wild-type p53 protein activates the WAF1/CIP-1 (p21) gene, leading to G1 arrest after DNA damage. The authors investigated the relation of p21 and p53 expression in pancreatic adenocarcinomas to disease stage, overall patient survival, and survival when chemotherapy or radiation therapy was given. METHODS:P...

journal_title：Cancer

authors： Dergham ST,Dugan MC,Joshi US,Chen YC,Du W,Smith DW,Arlauskas P,Crissman JD,Vaitkevicius VK,Sarkar FH

更新日期：1997-08-01 00:00:00

abstract：:Three-hundred whole thyroid glands were collected at autopsy from patients who had no known clinical history of thyroid disease, and who varied from 13 to 82 years of age; 200 were male and 100 female. Thyroid glands were weighed, measured, and examined after previous formalin fixation. Histologic examination was done...

journal_title：Cancer

authors： Bisi H,Fernandes VS,de Camargo RY,Koch L,Abdo AH,de Brito T

更新日期：1989-11-01 00:00:00

abstract：:Vitamin B6 is involved in many biological processes of potential relevance to carcinogenesis and tumor growth, including DNA synthesis and maintenance of immunocompetence, yet very little information exists on B6 nutritional status in childhood leukemia. Using a radioenzymatic assay, the authors measured plasma pyrido...

journal_title：Cancer

authors： Pais RC,Vanous E,Hollins B,Faraj BA,Davis R,Camp VM,Ragab AH

更新日期：1990-12-01 00:00:00

abstract：:The clinical, morphologic, and immunohistochemical features of 5 cases of peripheral T-cell lymphoma with lymph node and skin involvement are reported. All patients were male and presented with generalized lymphadenopathy and skin lesions. Lymph node biopsy specimens showed a diffusely growing, pleomorphic, atypical l...

journal_title：Cancer

authors： van den Oord JJ,De Wolf-Peeters C,Frizzera G,Desmet VJ,Tricot G,Thomas J,Marien K,Gatter KC,Mason DY

更新日期：1985-04-15 00:00:00

abstract：:Experience with high-dose cytosine arabinoside (HDAC) in pediatric solid tumors is limited. Sixteen children with solid tumors resistant to conventional therapies were registered in a pilot Pediatric Oncology Group (POG) study that required the administration of HDAC at 3 g/m2 every 12 hours for four doses. There were...

journal_title：Cancer

authors： Tebbi CK,Krischer J,Fernbach DJ,Mahoney DH,Alvarado C,Camitta B

更新日期：1990-11-15 00:00:00

abstract：BACKGROUND:The Women's Health Initiative randomized clinical trial reported that menopausal hormone therapy increases lung cancer mortality risk. If this is true, use of anti-estrogens should be associated with decreased lung cancer mortality risk. The authors compared lung cancer incidence and mortality among breast c...

journal_title：Cancer

authors： Bouchardy C,Benhamou S,Schaffar R,Verkooijen HM,Fioretta G,Schubert H,Vinh-Hung V,Soria JC,Vlastos G,Rapiti E

更新日期：2011-03-15 00:00:00

abstract：:Seventeen patients with adenocystic carcinoma have received 34 adequate trials of chemotherapy at Princess Margaret Hospital since 1969. There have been five objective responses to chemotherapy in 4 cases, lasting from five to 24 months, and 3 other patients have had stabilized disease for a period of five to seven mo...

journal_title：Cancer

authors： Tannock IF,Sutherland DJ

更新日期：1980-08-01 00:00:00

abstract：:The circulating levels of four tumor- or trophoblast-associated antigens were measured by specific radioimmunoassays in 11 patients with gestational choriocarcinoma. The estimations were carried out at the time when the urinary gonadotropin (hCG) excretion was low or negligible. Gonadotropin, measured as the hCG beta-...

journal_title：Cancer

authors： Seppälä M,Rutanen EM,Ranta T,Aho I,Nieminen U,Unnérus HA,Saksela E

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Although cutaneous desmoplastic malignant melanoma (DMM) has been well characterized, those arising from the oral mucosa have been less well defined. METHODS:We evaluated the clinical and pathologic features of three patients with biopsy-proven DMM examined at the North Carolina Baptist Hospital. Routine he...

journal_title：Cancer

authors： Kilpatrick SE,White WL,Browne JD

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:In animal models carbogen (normobaric 95% oxygen, 5% carbon dioxide) provides significant enhancement of local tumor control with fractionated radiotherapy. This approach to radiosensitization has been evaluated in the treatment of patients with bladder carcinoma using radical radiotherapy. METHODS:Sixty-on...

journal_title：Cancer

authors： Hoskin PJ,Saunders MI,Dische S

更新日期：1999-10-01 00:00:00

abstract：:In 14 patients by bilateral retroperitoneal lymph node dissection for nonseminoma tumors of the testes, several sexual functions before and after node dissection were compared. All patients had normal sexual function before the operation. After the operation, antegrade ejaculation was found to have disappeared complet...

journal_title：Cancer

authors： Nijman JM,Jager S,Boer PW,Kremer J,Oldhoff J,Koops HS

更新日期：1982-12-15 00:00:00

abstract：:Thin-needle aspiration biopsy (TNAB) was performed on 22 patients with orbital tumors. Nine patients were studied before the introduction of computed tomography (CT) and only two cytologic diagnoses could be established. Thirteen aspiration biopsies guided by CT were successful. The technique of the CT-guided TNAB of ...

journal_title：Cancer

authors： Czerniak B,Woyke S,Daniel B,Krzysztolik Z,Koss LG

更新日期：1984-12-01 00:00:00

abstract：:Local and systemic toxicities associated with hepatic arterial infusion of human recombinant tumor necrosis factor (rTNF) were studied in healthy adult mongrel dogs. The animals received saline containing human serum albumin with or without rTNF (0.02, 0.2, or 2.0 mg/m2). Arteriograms were made, and blood samples were...

journal_title：Cancer

authors： Ohkawa S,Wright KC,Mahajan H,Mavligit GM,Wallace S

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Immunophenotypic analysis is an established tool in the diagnosis and classification of many hematolymphoid disorders; however, the role of flow cytometry (FC) in detecting bone marrow involvement during the staging of non-Hodgkin lymphoma (NHL) has yet to be defined. METHODS:The authors retrospectively ana...

journal_title：Cancer

authors： Duggan PR,Easton D,Luider J,Auer IA

更新日期：2000-02-15 00:00:00

abstract：BACKGROUND:Effective management of symptoms in cancer patients requires early intervention. This study assessed whether the timing of referral to the Supportive Care Center (SCC) and symptom burden outcome varied by race or ethnicity in lung cancer patients who had been seen at a tertiary cancer center. METHODS:Non-Hi...

journal_title：Cancer

authors： Reyes-Gibby CC,Anderson KO,Shete S,Bruera E,Yennurajalingam S

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Malnutrition is a common complication of cancer treatment; it can affect energy levels and, as a consequence, quality of life. The goal of the current study was to evaluate the effect of dietetic intervention in a cohort of children treated for medulloblastoma and supratentorial primitive neuroectodermal tum...

journal_title：Cancer

authors： Bakish J,Hargrave D,Tariq N,Laperriere N,Rutka JT,Bouffet E

更新日期：2003-09-01 00:00:00