Hepatic arterial infusion of human recombinant tumor necrosis factor-alpha. An experimental study in dogs.

abstract：:This report identifies five general conclusions that emerged from the Second Workshop on Methodology in Behavioral and Psychosocial Cancer Research. These conclusions address diverse topics, including a focus on areas other than methodology; an emphasis on the transfer of technology and knowledge to applied settings; ...

journal_title：Cancer

authors： Burish TG

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Brain metastases from soft tissue sarcoma (STS) are uncommon. To the authors' knowledge limited information is available regarding the influence of the initial STS site, the significance of parenchymal versus leptomeningeal metastases, and the role of surgical resection. METHODS:STS patients evaluated betwe...

journal_title：Cancer

authors： Espat NJ,Bilsky M,Lewis JJ,Leung D,Brennan MF

更新日期：2002-05-15 00:00:00

abstract：BACKGROUND:Immunophenotypic analysis is an established tool in the diagnosis and classification of many hematolymphoid disorders; however, the role of flow cytometry (FC) in detecting bone marrow involvement during the staging of non-Hodgkin lymphoma (NHL) has yet to be defined. METHODS:The authors retrospectively ana...

journal_title：Cancer

authors： Duggan PR,Easton D,Luider J,Auer IA

更新日期：2000-02-15 00:00:00

abstract：:The National Cancer Institute (NCI) has increased its emphasis in cancer prevention by undertaking a number of human intervention trials. Special emphasis is placed on chemoprevention, diet, and smoking and tobacco use. Some 24 clinical trials are ongoing in chemoprevention to assess the role of specific chemicals (na...

journal_title：Cancer

authors： Cullen JW

更新日期：1988-10-15 00:00:00

abstract：:Four patients with benign giant cell tumor and one patient with probable benign giant cell tumor associated with Paget's disease of bone are reported. The familial and geographic clustering of these cases is unique in that three patients were related and all patients traced ancestral roots to the same area of southern...

journal_title：Cancer

authors： Jacobs TP,Michelsen J,Polay JS,D'Adamo AC,Canfield RE

更新日期：1979-08-01 00:00:00

abstract：:The hematologic factors of 16 female patients with breast carcinoma who had received adjuvant chemotherapy with L-phenylalanine-based programs for two years were compared with those for 13 normal female volunteers of similar age. The findings include significant suppression of the mean hemoglobin level, of leukocyte c...

journal_title：Cancer

authors： Corder MP,Jochimsen PR

更新日期：1982-06-15 00:00:00

abstract：BACKGROUND:Papanicolaou smear sensitivity for cervical adenocarcinoma (CVCA) is not well established. Also uncertain are the relative contributions to falsely negative diagnoses of sampling, screening, and interpretive errors. METHODS:Papanicolaou smears were identified from all patients at our institutions with biops...

journal_title：Cancer

authors： Krane JF,Granter SR,Trask CE,Hogan CL,Lee KR

更新日期：2001-02-25 00:00:00

abstract：BACKGROUND:The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. METHODS:The authors conducted a retrospective multicenter study of 12,262 patients who were treated between January 1980 and 31 December 2013 in French Sarcoma Group centers and enrolled...

journal_title：Cancer

authors： Penel N,Coindre JM,Giraud A,Terrier P,Ranchere-Vince D,Collin F,Guellec SLE,Bazille C,Lae M,de Pinieux G,Ray-Coquard IL,Bonvalot S,Cesne ALE,Robin YM,Stoeckle E,Toulmonde M,Blay JY

更新日期：2018-03-15 00:00:00

abstract：:Twenty patients with malignant hepatoma were treated with sequential intraarterial doxorubicin (72-hour continuous infusion) followed by systemic 5-fluorouracil (5-FU) and semustine (methyl CCNU). Objective tumor responses were seen in three patients (15%). The durations of response were 6, 19, and 27+ months, respect...

journal_title：Cancer

authors： O'Connell MJ,Hahn RG,Rubin J,Moertel CG

更新日期：1988-09-15 00:00:00

abstract：BACKGROUND:The mortality rate associated with fever accompanied by pulmonary infiltrates after chemotherapy for hematologic malignancies remains higher than the corresponding rate associated with febrile neutropenia without pulmonary infiltrates. Nonetheless, few studies have focused on the factors that predict outcome...

journal_title：Cancer

authors： Offidani M,Corvatta L,Malerba L,Marconi M,Bichisecchi E,Cecchini S,Manso E,Principi T,Gasparini S,Leoni P

更新日期：2004-08-01 00:00:00

abstract：:Pretreatment biopsy material of 82 cases of follicular lymphoma of lymph node origin was reviewed. According to the amount of small lymphocytes in the parafollicular lymphoid tissue (PSL), tumors were classified: PSL++, abundant lymphocytes with prominent postcapillary venules; PSL+, a number of lymphocytes readily re...

journal_title：Cancer

authors： Ree HJ,Leone LA

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Telomerase is an enzyme that can reconstitute the ends (telomeres) of chromosomes after cell division and thus circumvent the cumulative damage that occurs in normal adult somatic cells during successive mitotic cycles. Recently, it has been proposed that this enzyme should, therefore, be detectable in immor...

journal_title：Cancer

authors： Yoshida K,Sugino T,Tahara H,Woodman A,Bolodeoku J,Nargund V,Fellows G,Goodison S,Tahara E,Tarin D

更新日期：1997-01-15 00:00:00

abstract：BACKGROUND:Surveillance, Epidemiology, and End Results (SEER) data for the years 1973-1992 documented that patients age < 50 years presented with more advanced disease. Because of the increase in the incidence rate of lung adenocarcinoma in the past few decades and the presentation of more advanced disease in young pat...

journal_title：Cancer

authors： Liu NS,Spitz MR,Kemp BL,Cooksley C,Fossella FV,Lee JS,Hong WK,Khuri FR

更新日期：2000-04-15 00:00:00

abstract：BACKGROUND:The combination of paclitaxel with cisplatin or carboplatin has become the preferred chemotherapy regimen in the treatment of epithelial ovarian carcinoma. Anthracyclines also have activity in this disease. We conducted a Phase II study by using the combination of paclitaxel, cisplatin, and epirubicin for th...

journal_title：Cancer

authors： Papadimitriou CA,Moulopoulos LA,Vlahos G,Voulgaris Z,Kiosses E,Georgoulias N,Gika D,Diakomanolis E,Michalas S,Dimopoulos MA

更新日期：2000-10-01 00:00:00

abstract：:Retinoblastoma should not be considered as the exceptional childhood cancer that shows dominant inheritance, but rather as the typical childhood cancer that embraces a prezygotic and postzygotic subgroup. Postzygotic cases are conceived as involving mutation as a first step too, but with the mutation in somatic rather...

journal_title：Cancer

authors： Knudson AG Jr

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Monitoring therapy in patients with brain tumors is very difficult and unreliable. It has been shown that there is no good correlation between tumor sensitivity measured in vitro and in situ tumor response to therapies. METHODS:Sequential changes in tumor size, number of DNA synthesizing cells (labelling in...

journal_title：Cancer

authors： Takeda N,Diksic M,Yamamoto YL

更新日期：1996-03-15 00:00:00

abstract：:A patient with metastatic islet cell carcinoma of the pancreas, recurrent peptic ulcer disease, and hypergastrinemia (Zollinger-Ellison syndrome) developed symptomatic hypercalcemia and renal insufficiency; she was treated with streptozotocin after parathyroidectomy failed to control her hypercalcemia. Shortly after s...

journal_title：Cancer

authors： Cryer PE,Hill GJ II

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Wild-type p53 protein activates the WAF1/CIP-1 (p21) gene, leading to G1 arrest after DNA damage. The authors investigated the relation of p21 and p53 expression in pancreatic adenocarcinomas to disease stage, overall patient survival, and survival when chemotherapy or radiation therapy was given. METHODS:P...

journal_title：Cancer

authors： Dergham ST,Dugan MC,Joshi US,Chen YC,Du W,Smith DW,Arlauskas P,Crissman JD,Vaitkevicius VK,Sarkar FH

更新日期：1997-08-01 00:00:00

abstract：:A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleur...

journal_title：Cancer

authors： Karn CM,Socinski MA,Fletcher JA,Corson JM,Craighead JE

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

journal_title：Cancer

authors： Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

更新日期：2002-05-15 00:00:00

abstract：:A patient developed widely metastatic adenoid cystic carcinoma of the parotid gland after several local recurrences. A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C. This is the second complete response ...

journal_title：Cancer

authors： Budd GT,Groppe CW

更新日期：1983-02-15 00:00:00

abstract：BACKGROUND:Failure to obtain the requisite follow-up of patients with abnormal mammograms may delay cancer diagnosis and impact outcome. Up to 20% of women do not receive timely recommended follow-up. The current study tested the accuracy of the linkage of payer claims and clinical data to identify the appropriate trea...

journal_title：Cancer

authors： Eberl MM,Watroba N,Reinhardt M,Pomerantz J,Serghany J,Broffman G,Fox CH,Mahoney MC,Edge SB

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Insulin-like growth factor I (IGF-I) is a potent mitogen for breast cancer cells. The majority of IGF-I in plasma is bound to IGF binding proteins (IGFBPs), which modulate the biologic effects of IGF-I. METHODS:Plasma concentrations of IGF-I, IGFBP-I, and IGFBP-3 were compared between 40 postmenopausal brea...

journal_title：Cancer

authors： Lahti EI,Knip M,Laatikainen TJ

更新日期：1994-07-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine risk factors that affect locoregional control of nasopharyngeal carcinoma (NPC) after radiotherapy. Computed tomography (CT) is utilized for radiotherapy planning and for identifying high risk anatomic areas. METHODS:Between April 1990 and December 1993, 40 consecu...

journal_title：Cancer

authors： Jian JJ,Cheng SH,Prosnitz LR,Tsai SY,Tsai MJ,Huang AT

更新日期：1998-01-15 00:00:00

abstract：:Androgen receptors (AR) and estrogen receptors (ER) were consecutively assayed for hepatocellular carcinoma (HCC) and the surrounding liver was removed surgically from 19 female patients. Patient age ranged from 43 to 79 years, with an average of 61 +/- 9 years. All patients had underlying liver disease (liver cirrhos...

journal_title：Cancer

authors： Nagasue N,Kohno H,Chang YC,Hayashi T,Utsumi Y,Nakamura T,Yukaya H

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Tumor volume in radical prostatectomies can be determined by several different techniques and appears to predict clinical progression. Greatest tumor dimension and area are easily obtained measures that are both correlated with tumor volume. The authors sought to determine whether greatest tumor dimension an...

journal_title：Cancer

authors： Renshaw AA,Richie JP,Loughlin KR,Jiroutek M,Chung A,D'Amico AV

更新日期：1998-08-15 00:00:00

abstract：BACKGROUND:Randomized controlled trials (RCTs) are commonly used to inform clinical practice; however, it is unclear how generalizable RCT data are to patients in routine clinical practice. The authors of this report assessed the availability and applicability of randomized evidence guiding medical decisions in a cohor...

journal_title：Cancer

authors： Apisarnthanarax S,Swisher-McClure S,Chiu WK,Kimple RJ,Harris SL,Morris DE,Tepper JE

更新日期：2013-08-15 00:00:00

abstract：:The establishment and characterization of 11 human lung cancer cell lines are described in this article. Nine of these cell lines were established over a 5-year period, from 1983 to 1988, from patients treated at the Kingston Regional Cancer Centre. These include eight definite or probable small cell lung cancer (SCLC...

journal_title：Cancer

authors： Campling BG,Haworth AC,Baker HM,Greer DL,Holden JJ,Bradley EC,Pym J,Dexter DF

更新日期：1992-04-15 00:00:00

abstract：BACKGROUND:Image-guided radiation therapy (IGRT) is a novel array of in-room imaging modalities that are used for tumor localization and patient setup in radiation oncology. The prevalence of IGRT use among US radiation oncologists is unknown. METHODS:A random sample of 1600 radiation oncologists was surveyed by Inter...

journal_title：Cancer

authors： Simpson DR,Lawson JD,Nath SK,Rose BS,Mundt AJ,Mell LK

更新日期：2010-08-15 00:00:00

abstract：BACKGROUND:Ribonucleotide reductase M1 (RRM1) is an important molecule in different types of cancer. The objective of this study was to evaluate the predictive roles of RRM1 in the survival of patients with resectable pancreatic adenocarcinoma who received treatment with gemcitabine or nongemcitabine adjuvant therapy. ...

journal_title：Cancer

authors： Xie H,Jiang W,Jiang J,Wang Y,Kim R,Liu X,Liu X

更新日期：2013-01-01 00:00:00