Cardiac synovial sarcoma with translocation (X;18) associated with asbestos exposure.

Abstract:

:A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleural plaques indicative of asbestos exposure. These findings raise questions about the possible causation of this tumor.

journal_name

Cancer

journal_title

Cancer

authors

Karn CM,Socinski MA,Fletcher JA,Corson JM,Craighead JE

doi

10.1002/1097-0142(19940101)73:1<74::aid-cncr282073

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

74-8

issue

1

eissn

0008-543X

issn

1097-0142

journal_volume

73

pub_type

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