Clinical relevance of Ki-67 expression in bone tumors.

abstract：BACKGROUND:The identification of the BRCA1 gene is a powerful tool for predicting a patient's lifetime risk for carcinoma of the breast and ovary when she has hereditary breast/ovarian carcinoma (HBOC) syndrome. The process of BRCA1 testing and genetic counseling and participants' reactions to test results, are describ...

journal_title：Cancer

authors： Lynch HT,Lemon SJ,Durham C,Tinley ST,Connolly C,Lynch JF,Surdam J,Orinion E,Slominski-Caster S,Watson P,Lerman C,Tonin P,Lenoir G,Serova O,Narod S

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Local recurrence is the most frequent site of failure after resection for pancreatic cancer. Tolerance, local control, and survival obtained by the association of resection and intraoperative radiation therapy (IORT) were reported. METHODS:Between June 1985 and March 1993, 90 resections for pancreatic cance...

journal_title：Cancer

authors： Zerbi A,Fossati V,Parolini D,Carlucci M,Balzano G,Bordogna G,Staudacher C,Di Carlo V

更新日期：1994-06-15 00:00:00

abstract：BACKGROUND:Gastric carcinoma with lymphoid stroma (GCLS) has been reported to have a more favorable prognosis than ordinary gastric carcinoma, however, the precise mechanism of the pathogenesis for GCLS remains unclear. METHODS:The authors analyzed 99 GCLS in 94 patients for Epstein-Barr virus (EBV) sequences using po...

journal_title：Cancer

authors： Nakamura S,Ueki T,Yao T,Ueyama T,Tsuneyoshi M

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Despite the widespread use of Papanicolaou (Pap) smear screening, substantial morbidity and mortality from cervical carcinoma continue in the U.S. Although access to screening is a major barrier to use of the Pap smear, invasive cervical carcinoma (ICC) still is observed in health plan members who have compr...

journal_title：Cancer

authors： Sung HY,Kearney KA,Miller M,Kinney W,Sawaya GF,Hiatt RA

更新日期：2000-05-15 00:00:00

abstract：BACKGROUND:To evaluate the pathologic characteristics of the primary tumor relative to local control, survival, and freedom from distant metastases, an analysis was performed of 172 patients with ductal carcinoma in situ (intraductal carcinoma) of the breast treated with breast-conserving surgery and definitive breast ...

journal_title：Cancer

authors： Solin LJ,Yeh IT,Kurtz J,Fourquet A,Recht A,Kuske R,McCormick B,Cross MA,Schultz DJ,Amalric R

更新日期：1993-04-15 00:00:00

abstract：:Two cases of occult seminoma were observed which showed left-sided lymph node metastases without clinically demonstrable testicular tumors. The peculiar histology of the lymph node metastases, namely PAS-positive tumor cells with clear cytoplasm together with a granulomatous stromal reaction, was highly suggestive of ...

journal_title：Cancer

authors： Richter HJ,Leder LD

更新日期：1979-07-01 00:00:00

abstract：:We have reviewed the records of 76 patients with Stage I or II extranodal non-Hodgkin's lymphoma who were referred to the Division of Radiation Oncology, Mallinckrodt Institute of Radiology, during the years 1964 through 1974. The histologic slides were reviewed in the 67 cases in which they were available. Forty-thre...

journal_title：Cancer

authors： Mill WB,Lee FA,Franssila KO

更新日期：1980-02-15 00:00:00

abstract：:Over the last 20 to 30 years, a recognition and general acceptance of the entity of malignant fibrous histiocytoma and monophasic synovial sarcoma has occurred. The introduction of these diagnostic categories among the generic group of spindle cell sarcomas now requires a reevaluation of the more traditional and histo...

journal_title：Cancer

authors： Scott SM,Reiman HM,Pritchard DJ,Ilstrup DM

更新日期：1989-08-15 00:00:00

abstract：:Two siblings succumbed to glioblastoma multiforme, associated with hepatic focal nodular hyperplasia and cafe-au-lait spots. One sibling had syndactyly and multiple colonic polyps, while the other had an angiomatous malformation in the brain. Their mother died of myasthenia gravis. The findings suggest a hamartomatous...

journal_title：Cancer

authors： Everson RB,Fraumeni JF Jr

更新日期：1976-07-01 00:00:00

abstract：:Fifteen patients developed acute nonlymphocytic leukemia (ANLL) 31 to 182 months following chemotherapy and/or radiotherapy for various malignancies and one non-neoplastic disorder. The ANLL was commonly heralded by a brief preleukemic phase consisting of cytopenias and a variety of morphologic abnormalities. At diagn...

journal_title：Cancer

authors： Foucar K,McKenna RW,Bloomfield CD,Bowers TK,Brunning RD

更新日期：1979-04-01 00:00:00

abstract：:Non-Hodgkin's lymphoma localized to the mediastinum and adjacent structures occurred in 12 of 215 (6+) non-Hodgkin's lymphoma patients seen at the Massachusetts General Hospital between 1975 and 1979. Lymphangiography, radionuclide scanning and whole body computerized tomography were used to exclude patients with extr...

journal_title：Cancer

authors： Levitt LJ,Aisenberg AC,Harris NL,Linggood RM,Poppema S

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:It remains controversial whether modified radical neck dissection (MRND) for patients with papillary thyroid carcinoma improves prognosis. However, it is highly probable that the incidence of local recurrence is reduced by lymph node dissection. Sentinel lymph node (SLN) biopsy (SLNB) for patients with melan...

journal_title：Cancer

authors： Fukui Y,Yamakawa T,Taniki T,Numoto S,Miki H,Monden Y

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND METHODS:The antiemetic activity of ondansetron (Zofran, Glaxo Pharmaceuticals, Research Triangle Park, NC) was evaluated in 25 patients with recurrent melanoma who were treated sequentially with dacarbazine (DTIC), vinblastine, and cisplatin. The antiemetic regimen included ondansetron alone in 11 patien...

journal_title：Cancer

authors： Legha SS,Hodges C,Ring S

更新日期：1992-10-01 00:00:00

abstract：:The cytogenetic findings in 31 liposarcomas from 26 patients are reported. Four other tumors did not grow. Three histologic types are represented in this analysis. The well-differentiated liposarcomas were characterized by telomeric associations, large marker chromosomes and ring chromosomes, and in some cases, double...

journal_title：Cancer

authors： Sreekantaiah C,Karakousis CP,Leong SP,Sandberg AA

更新日期：1992-05-15 00:00:00

abstract：:One hundred eighty-nine patients received a four-drug combination consisting of cyclophosphamide, Oncovin (vincristine), methyl CCNU, and bleomycin (COMB), according to three different drug regimens, performed sequentially. Of the 189, 62 had a partial response (33%) including 11/33 with squamous lung cancer, 11/32 wi...

journal_title：Cancer

authors： Livingston RB,Einhorn LH,Bodey GP,Burgess MA,Freireich EJ,Gottlieb JA

更新日期：1975-08-01 00:00:00

abstract：:The unique case of a 60-year-old patient with a non-Hodgkin's B-cell lymphoma of the lymphoplasmacytic type and three associated monoclonal proteins, is described. The patient also exhibited various autoimmune phenomena that were consistent with the diagnoses of Sjögren's syndrome and autoimmune thyroiditis. The evolu...

journal_title：Cancer

authors： Berg AR,Weisenburger DD,Linder J,Armitage JO

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Lenvatinib is an oral, multitargeted tyrosine kinase inhibitor of the vascular endothelial growth factor receptors 1 through 3 (VEGFR1-VEGFR3), fibroblast growth factor receptors 1 through 4 (FGFR1-FGFR4), platelet-derived growth factor receptor α (PDGFRα), ret proto-oncogene (RET), and v-kit Hardy-Zuckerman...

journal_title：Cancer

authors： Cabanillas ME,Schlumberger M,Jarzab B,Martins RG,Pacini F,Robinson B,McCaffrey JC,Shah MH,Bodenner DL,Topliss D,Andresen C,O'Brien JP,Ren M,Funahashi Y,Allison R,Elisei R,Newbold K,Licitra LF,Sherman SI,Ball DW

更新日期：2015-08-15 00:00:00

abstract：BACKGROUND:Partial splenic embolization (PSE) has been used to improve hematologic parameters related to hypersplenism. The purpose of this study was to review our institutional experience with PSE for cancer patients with thrombocytopenia because of splenic sequestration precluding the administration of systemic thera...

journal_title：Cancer

authors： Kauffman CR,Mahvash A,Kopetz S,Wolff RA,Ensor J,Wallace MJ

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:In a previous study of gene array data, the authors identified survivin as a candidate marker of aggressiveness in clear cell renal cell carcinoma (ccRCC). What remained in question was whether survivin expression at the protein level is an independent predictor of disease progression and cancer-specific sur...

journal_title：Cancer

authors： Parker AS,Kosari F,Lohse CM,Houston Thompson R,Kwon ED,Murphy L,Riehle DL,Blute ML,Leibovich BC,Vasmatzis G,Cheville JC

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Age-related disparities in colon cancer treatment exist, with older patients being less likely to receive recommended therapy. However, to the authors' knowledge, few studies to date have focused on receipt of surgery. The objective of the current study was to describe patterns of surgery in patients aged ≥ ...

journal_title：Cancer

authors： Neuman HB,O'Connor ES,Weiss J,Loconte NK,Greenblatt DY,Greenberg CC,Smith MA

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Whether patient navigation improves outcomes for patients with comorbidities is unknown. The aims of this study were to determine the effect of comorbidities on the time to diagnostic resolution after an abnormal cancer screening test and to examine whether patient navigation improves the timeliness and like...

journal_title：Cancer

authors： Whitley EM,Raich PC,Dudley DJ,Freund KM,Paskett ED,Patierno SR,Simon M,Warren-Mears V,Snyder FR,Patient Navigation Research Program Investigators.

更新日期：2017-01-01 00:00:00

abstract：:Of a total of 1561 patients registered in the Intergroup Rhabdomyosarcoma Study (IRS) as of May 1983, 78 patients (5%) were younger than 1 year of age. These infants did not differ from the older children (1-20 years of age) in male/female ratio, clinical grouping, or survival rates. Infants younger than 1 year of age...

journal_title：Cancer

authors： Ragab AH,Heyn R,Tefft M,Hays DN,Newton WA Jr,Beltangady M

更新日期：1986-12-15 00:00:00

abstract：BACKGROUND:Insulin-like growth factor I (IGF-I) is a potent mitogen for breast cancer cells. The majority of IGF-I in plasma is bound to IGF binding proteins (IGFBPs), which modulate the biologic effects of IGF-I. METHODS:Plasma concentrations of IGF-I, IGFBP-I, and IGFBP-3 were compared between 40 postmenopausal brea...

journal_title：Cancer

authors： Lahti EI,Knip M,Laatikainen TJ

更新日期：1994-07-15 00:00:00

abstract：:Prostate cancer is the most common male malignancy and the second or third leading cause of cancer death among men in the West. The descriptive epidemiology of prostate cancer suggests that it is a preventable disease. Prevention has the theoretical advantage of not only saving lives, but also reduce the morbidity of ...

journal_title：Cancer

authors： Fleshner N,Zlotta AR

更新日期：2007-11-01 00:00:00

abstract：:The Southwest Oncology Group in a prospective randomized study compared one year of adjuvant combination chemotherapy with continuous CMFVP to two years of intermittent L-PAM in women with operable breast cancer with histologically positive axillary lymph nodes. In fully evaluable patients with a 42-month median and 3...

journal_title：Cancer

authors： Glucksberg H,Rivkin SE,Rasmussen S,Tranum B,Gad-el-Mawla N,Costanzi J,Hoogstraten B,Athens J,Maloney T,McCracken J,Vaughn C

更新日期：1982-08-01 00:00:00

abstract：:Results from the standpoint of survival rates and locoregional failures are compared in three series of patients having had a radical mastectomy for breast cancer: (1) radical mastectomy alone for the patients who had essentially outer quadrant lesions and a negative axilla; (2) postoperative irradiation when the axil...

journal_title：Cancer

authors： Rodger A,Montague ED,Fletcher G

更新日期：1983-04-15 00:00:00

abstract：:Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...

journal_title：Cancer

authors： Reddy S,Saxena VS,Hendrickson F,Deutsch W

更新日期：1981-02-15 00:00:00

abstract：:Nineteen postmenopausal patients with metastatic breast cancer refractory to conventional combination chemotherapy were treated with monthly cycles with the combinations of vinblastine, adriamycin, thiotepa and halotestin. Ten patients (52%) responded with a greater than 50% regression of measurable tumor. The median ...

journal_title：Cancer

authors： Perloff M,Hart RD,Holland JF

更新日期：1978-12-01 00:00:00

abstract：:The histologic types of lung cancer in 855 patients (747 men and 107 women) from three hospitals and one international study of insulation workers were evaluated. Of these, 196 cases had asbestos exposure. About one half of the cases were diagnosed from surgical slides and one half from autopsy slides. Squamous cell c...

journal_title：Cancer

authors： Auerbach O,Garfinkel L,Parks VR,Conston AS,Galdi VA,Joubert L

更新日期：1984-12-15 00:00:00

abstract：BACKGROUND:: Patients with oral premalignant lesions (OPL) present with oral squamous cell carcinomas (OSCC) at a much higher rate than the general population. There are currently no useful markers that indicate specifically which OPLs are most likely to progress. Three small integrin binding ligands N-linked glycoprot...

journal_title：Cancer

authors： Ogbureke KU,Abdelsayed RA,Kushner H,Li L,Fisher LW

更新日期：2010-04-01 00:00:00