The treatment of ejaculation disorders after retroperitoneal lymph node dissection.

Abstract:

:In 14 patients by bilateral retroperitoneal lymph node dissection for nonseminoma tumors of the testes, several sexual functions before and after node dissection were compared. All patients had normal sexual function before the operation. After the operation, antegrade ejaculation was found to have disappeared completely in 12 patients, retrograde ejaculation was demonstrable in ten of these patients. In ten patients, antegrade ejaculation was restored after treatment with 25 mg imipramine twice daily by mouth. In the two patients who still showed antegrade ejaculation, albeit diminished, imipramine medication led to an increased number of spermatoza. During imipramine medication, the partners of five patients became pregnant. The preliminary conclusion from these findings is that ejaculation disorders, which most males develop after bilateral retroperitoneal lymph node dissection, can be successfully treated with daily oral doses of 25-50 mg imipramine in the majority of patients who still desire children.

journal_name

Cancer

journal_title

Cancer

authors

Nijman JM,Jager S,Boer PW,Kremer J,Oldhoff J,Koops HS

doi

10.1002/1097-0142(19821215)50:12<2967::aid-cncr282

subject

Has Abstract

pub_date

1982-12-15 00:00:00

pages

2967-71

issue

12

eissn

0008-543X

issn

1097-0142

journal_volume

50

pub_type

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