Indomethacin-mediated enhancement of lymphocyte response to mitogens in healthy subjects and lung cancer patients.

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：BACKGROUND:Multiple cell-signaling ligands and receptors-including vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), endothelial growth factor (EGF), v-akt murine thymoma viral oncogene homolog (AKT), platelet-derived growth factor (PDGF), mitogen-activated protein kinase (MAPK), and 70-kilod...

journal_title：Cancer

authors： Abdeen A,Chou AJ,Healey JH,Khanna C,Osborne TS,Hewitt SM,Kim M,Wang D,Moody K,Gorlick R

更新日期：2009-11-15 00:00:00

abstract：:Associations were sought between specific histocompatibility antigens (HLA) of the human major histocompatibility complex and the incidence of head and neck squamous cell carcinoma (SqCC). Seventy sequential patients with SqCC and 217 control subjects from the same geographic region were typed for HLA-A, HLA-B, and HL...

journal_title：Cancer

authors： Houck JR,Romano PJ,Bartholomew M,Smith PJ,Kloszewski F,Vesell ES

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:The differential diagnosis of severe acute respiratory syndrome (SARS) in patients with cancer can be challenging. Although diagnostic criteria for SARS have been issued by the World Health Organization (WHO), simple adoption of the established criteria may lead to overdiagnosis in patients with cancer or to...

journal_title：Cancer

authors： Gu J,Wu A,Li J,Zhang X,Fang J,Li M,Yao Y,Ke Y,Gu J,Chen M,You W

更新日期：2004-04-01 00:00:00

abstract：:Mesenchymal chondrosarcoma of bone and soft tissues treated at the Istituto Ortopedico Rizzoli are reviewed. The skeletal locations were prominent in five cases. Only two cases were in the soft tissues. Radiographic picture in the bone shows an aggressive osteolysis, with soft tissues invasion. Histologic picture is t...

journal_title：Cancer

authors： Bertoni F,Picci P,Bacchini P,Capanna R,Innao V,Bacci G,Campanacci M

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:An epidermal growth factor receptor (EGFR) immunohistochemical detection system currently is being developed. The current study attempts to address background EGFR reactivity issues before determining the optimum EGFR scoring system. METHODS:Tissue sections from 102 patients with T3N1-2M1 colon adenocarcino...

journal_title：Cancer

authors： Goldstein NS,Armin M

更新日期：2001-09-01 00:00:00

abstract：:Twenty-six cases of anaplastic thyroid tumor were investigated and reclassified using immunoperoxidase techniques. Sections of the neoplasms were stained immunohistologically for the following thyroid associated antigens: (1) thyroglobulin, which shows a positive reaction with follicular cells of the thyroid; (2) calc...

journal_title：Cancer

authors： Shvero J,Gal R,Avidor I,Hadar T,Kessler E

更新日期：1988-07-15 00:00:00

abstract：BACKGROUND:Microsatellite instability (MIN) appears to be a novel molecular mechanism in carcinogenesis and is believed to reflect multiple replication errors. The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. The...

journal_title：Cancer

authors： Tanosaki S,Inokuchi K,Shimada T,Dan K

更新日期：1998-08-01 00:00:00

abstract：:Three screening programs for early cervical cancer currently in use in Japan were evaluated according to the following criteria: (1) economic effectiveness; (2) screening efficiency; and (3) access to medical care. The mobile program has the highest benefit-cost ratio (BCR, 1.20) and is hence most cost-effective; its ...

journal_title：Cancer

authors： Takenaga N,Kai I,Ohi G

更新日期：1985-05-15 00:00:00

abstract：:Several decades ago, it was reported that normal and malignant mesothelial cells were transformed into distinct cell types (epithelial to fibrous and fibrous to epithelial) when transferred to in vitro conditions. Those tissue culture data are still cited as evidence supporting that the mesothelial cell has multipoten...

journal_title：Cancer

authors： Suzuki Y,Chahinian AP,Ohnuma T

更新日期：1987-08-01 00:00:00

abstract：:Carcinomas of the pancreas with giant cells are not rare, but those containing osteoclast-like tumor cells are quite unusual. This report documents a pancreatic neoplasm comprising both easily recognizable well-differentiated adenocarcinoma and osteoclast-like tumor. The literature on the "osteoclastoma" of the pancre...

journal_title：Cancer

authors： Trepeta RW,Mathur B,Lagin S,LiVolsi VA

更新日期：1981-11-01 00:00:00

abstract：:The International Breast Cancer Study Group (formerly the Ludwig Group) has conducted nine clinical trials since 1978 (see the Appendix for participants and authors). Biologic hypotheses related to the combined use of chemotherapy and endocrine therapy in women with operable breast cancer were tested. Questions of tim...

journal_title：Cancer

authors： Goldhirsch A,Gelber RD,Castiglione M,Price KN,Rudenstam CM,Lindtner J,Collins J,Senn HJ,Brunner KW,Galligioni E

更新日期：1994-08-01 00:00:00

abstract：:During the past 30 years, changes in the treatment of children and adolescents with cancer have led to substantial improvements in survival. Although treatment-related factors have been shown to impact subsequent health status and quality of life, there is limited information on survivors who are now two or more decad...

journal_title：Cancer

authors： Robison LL,Green DM,Hudson M,Meadows AT,Mertens AC,Packer RJ,Sklar CA,Strong LC,Yasui Y,Zeltzer LK

更新日期：2005-12-01 00:00:00

abstract：:The potential role of paraneoplastic Cushing's syndrome (CS) was assessed on the clinical course of patients with small cell lung cancer. A retrospective comparison was done of complications and survival rates according to the presence or absence of CS in patients with small cell lung cancer who died within 90 days of...

journal_title：Cancer

authors： Dimopoulos MA,Fernandez JF,Samaan NA,Holoye PY,Vassilopoulou-Sellin R

更新日期：1992-01-01 00:00:00

abstract：:Two patients fulfilled the clinical and hematologic criteria for B-cell acute lymphoblastic leukemia: the malignant cells had L3 morphology, bore B-cell markers, and carried the specific t(8;14) translocation. The leukemic cells of one patient were tetrasomic for 1q, and those of the other patient showed several separ...

journal_title：Cancer

authors： Morris CM,Fitzgerald PH,Neville MA,Wyld PJ,Beard ME

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Sequential systematic biopsies after radiotherapy (RT) for prostate carcinoma were evaluated with respect to radiation effect, tumor differentiation, and prostate specific antigen (PSA) staining, and these histopathologic parameters were correlated with local outcome. METHODS:Since 1990, transrectal ultraso...

journal_title：Cancer

authors： Crook JM,Bahadur YA,Robertson SJ,Perry GA,Esche BA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:American Indians and Alaska Natives (AI/AN) experience higher morbidity and mortality from primary liver cancer than other United States (US) populations, but racial misclassification in medical records results in underestimates of disease burden. METHODS:To reduce misclassification, National Program of Can...

journal_title：Cancer

authors： Jim MA,Perdue DG,Richardson LC,Espey DK,Redd JT,Martin HJ,Kwong SL,Kelly JJ,Henderson JA,Ahmed F

更新日期：2008-09-01 00:00:00

abstract：:Activities of glucosephosphate isomerase, lactate dehydrogenase, and NADP-isocitrate dehydrogenase were significantly elevated in breast cancer specimens from patients who responded favorably to combination cytotoxic chemotherapy regimens compared with those in carcinomas from patients failing to respond to the same c...

journal_title：Cancer

authors： Hilf R,Savlov ED,Rector WD,Wittliff JL

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:The current study determined the efficacy and toxicity of weekly paclitaxel in combination with estramustine phosphate (EMP) in patients with androgen-independent prostate carcinoma (AIPC). METHODS:Patients with progressive AIPC received 90 mg/m2 paclitaxel by 1-hour intravenous infusion weekly for 3 weeks,...

journal_title：Cancer

authors： Vaughn DJ,Brown AW Jr,Harker WG,Huh S,Miller L,Rinaldi D,Kabbinavar F

更新日期：2004-02-15 00:00:00

abstract：:A bolus intravenous dose of 5-fluorouracil of 600 mg/M2 was added exactly 1 hour after methotrexate administration in an established combination program including bleomycin and cisplatin for advanced squamous cell cancer of the head and neck. Results were no better than those observed previously with the three drugs, ...

journal_title：Cancer

authors： Vogl SE,Komisar A,Kaplan BH,Engstrom PF,Kasule OH,Stolbach L,Lerner H,Muggia F

更新日期：1986-02-15 00:00:00

abstract：:The presence of hepatitis B virus (HBV) has been evaluated in liver specimens from 11 children with primary liver tumors and negative results of serologic testing for HBV markers. HBV-DNA sequences were detected by the polymerase chain reaction procedure, using different sets of oligonucleotide primers from highly con...

journal_title：Cancer

authors： Pontisso P,Morsica G,Ruvoletto MG,Barzon M,Perilongo G,Basso G,Cecchetto G,Chemello L,Alberti A

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Despite extensive investigation, the role of MDR of human cancer remains unclear. Canine lymphoma is a spontaneously arising correlate of human non-Hodgkin's lymphoma that may complement other in vivo models for investigation of issues related to MDR. METHODS:Immunoreactivity of primary antibodies to the hu...

journal_title：Cancer

authors： Lee JJ,Hughes CS,Fine RL,Page RL

更新日期：1996-05-01 00:00:00

abstract：:Ependymomas originating in the sacrum or extraspinal parasacral soft tissues are rare tumors. The majority are of the myxopapillary type and may be locally destructive. Even though metastases are not uncommon in retrosacral ependymomas, they have been rarely described in intrasacral locations. A case is reported of a ...

journal_title：Cancer

authors： Miralbell R,Louis DN,O'Keeffe D,Rosenberg AE,Suit HD

更新日期：1990-05-15 00:00:00

abstract：:A case of squamous cell carcinoma of the tongue in a 26-year-old man developing nine years after renal transplantation is presented. This is the first such case to be reported. Within seven months, widespread tumor metastases resulted in death. Pathologic examination of the transplanted kidney demonstrated neither re-...

journal_title：Cancer

authors： Lee YW,Gisser SD

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Workload is extensively regulated and often used as a measure of quality in gynecologic cytology. Whether workload correlates with the sensitivity of screening in gynecologic cytology is not known. METHODS:The sensitivity of gynecologic cytology screening was measured over an 8-month period using the result...

journal_title：Cancer

authors： Deschenes M,Renshaw AA,Auger M

更新日期：2008-06-25 00:00:00

abstract：BACKGROUND:Quantified, human hemoglobin (Hb)-specific, immunochemical fecal occult blood test (IFOBT) measurements are now used for colorectal cancer (CRC) screening. The objective was to evaluate sensitivity and specificity for CRC and advanced adenomatous polyps (APs) by the fecal Hb threshold used to determine a pos...

journal_title：Cancer

authors： Rozen P,Comaneshter D,Levi Z,Hazazi R,Vilkin A,Maoz E,Birkenfeld S,Niv Y

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Radiofrequency (RF) ablation is an increasingly applied technique. Promising results of hepatic RF ablation raised expectations of its capabilities for treatment of primary and secondary lung tumors. Because of different thermal and electrical properties of lung tissue, compared with liver tissue, a simple a...

journal_title：Cancer

authors： Clasen S,Krober SM,Kosan B,Aebert H,Fend F,Bomches A,Claussen CD,Pereira PL

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Patients who travel a long distance (≥50 miles) for cancer care have improved outcomes. However, to the authors' knowledge, the prevalence of long travel distances for treatment by patients with head and neck squamous cell carcinoma (HNSCC), and the effect of travel distance on overall survival (OS), remains...

journal_title：Cancer

authors： Graboyes EM,Ellis MA,Li H,Kaczmar JM,Sharma AK,Lentsch EJ,Day TA,Hughes Halbert C

更新日期：2018-08-01 00:00:00

abstract：:Why are older black women screened less for breast cancer? What can be done to narrow the racial gap in mammography screening? These are the questions addressed by the Save Our Sisters (SOS) Project, a pilot demonstration study funded by the National Cancer Institute in a rural county of North Carolina. The target pop...

journal_title：Cancer

authors： Eng E

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Adjuvant radiation has been proposed for the treatment of patients with desmoplastic melanoma, who reportedly have local recurrence rates as high as 40-60%. The authors investigated local recurrence rates at a tertiary referral center to determine the success of wide excision alone for patients with desmopla...

journal_title：Cancer

authors： Arora A,Lowe L,Su L,Rees R,Bradford C,Cimmino VC,Chang AE,Johnson TM,Sabel MS

更新日期：2005-10-01 00:00:00