Pathomorphologic evaluation of pulmonary radiofrequency ablation: proof of cell death is characterized by DNA fragmentation and apoptotic bodies.

abstract：:Histologic features similar to those present in angiosarcomas were found in organizing thrombi. Within the thrombi, freely anastomosing small channels, often lined by one or more layers of prominent, occasionally atypical, endothelial cells were noted. Papillary-like projections of organizing thrombus material lined b...

journal_title：Cancer

authors： Salyer WR,Salyer DC

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND:Interleukin-2 (IL-2) has immunomodulatory effects, including stimulating the activity of cytotoxic T cells and natural killer cells, and inducing the generation of lymphokine-activated killer cells. The authors investigated whether IL-2 may improve the duration of complete remission (CR) and survival in acut...

journal_title：Cancer

authors： Cortes JE,Kantarjian HM,O'Brien S,Giles F,Keating MJ,Freireich EJ,Estey EH

更新日期：1999-04-01 00:00:00

abstract：:Carcinoembryonic antigen is only a tumor assoicated antigen and is less clinically useful than the original report suggested. However, the CEA assays in clinical use utilize reagents operationally defined by old criteria. There is now abundant evidence that "CEA" consists of a heterogenous family of related glycoprote...

journal_title：Cancer

authors： Alpert E

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Patients with invasive breast carcinoma who are ages 35-40 years or younger at the time of diagnosis have been found in several studies to have worse prognosis and higher local failure rates after breast-conserving therapy (BCT) compared with older patients. However, it is uncertain whether specific clinical...

journal_title：Cancer

authors： Zhou P,Recht A

更新日期：2004-09-15 00:00:00

abstract：:To assess the value in Ewing's sarcoma of a new multiagent therapy (vincristine, cyclophosphamide, Adriamycin, (doxorubicin) procarbazine), 30 children with a localized tumor (eight distal, nine proximal, 13 central lesions) treated at the Institut Gustave-Roussy between 1973 and 1976 (E3), were pair-matched by site o...

journal_title：Cancer

authors： Zucker JM,Henry-Amar M,Sarrazin D,Blache R,Patte C,Schweisguth O

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：BACKGROUND:Differentiating primary glandular from high-grade squamous intraepithelial lesions (HSIL) that involve endocervical glands is not an uncommon diagnostic problem in liquid-based gynecological cytology. Squamous and atypical glandular cell lesions may show similar cytomorphologic features. The aim of this stud...

journal_title：Cancer

authors： Garcia MT,Acar BC,Jorda M,Gomez-Fernandez C,Ganjei-Azar P

更新日期：2007-02-25 00:00:00

abstract：:Routinely embedded tumors (116 cases) were screened immunohistochemically for the thyroid-associated antigens, thyroglobulin and calcitonin, and for carcinoembryonic antigen (CEA). Also the influence of different fixatives, decalcification, and embedding procedures were studied. All follicular and papillary carcinomas...

journal_title：Cancer

authors： Logmans SC,Jöbsis AC

更新日期：1984-07-15 00:00:00

abstract：:Over the years, there has been a continuous increase in clinically relevant driver mutations in patients with non-small cell lung cancer (NSCLC). Among these, dysregulated activation of the MET tyrosine kinase receptor has gained importance due to the recent development of quite effective treatments. MET dysregulation...

journal_title：Cancer

authors： Friedlaender A,Drilon A,Banna GL,Peters S,Addeo A

更新日期：2020-11-15 00:00:00

abstract：BACKGROUND:Nipple duct lavage (NDL) may be useful for breast cancer risk stratification. Published guidelines recommend that women with a 5-year Gail risk >/=1.7% should consider undergoing lavage for any fluid-yielding ducts, but it is not known whether increased breast cancer risk or nipple fluid production predict l...

journal_title：Cancer

authors： Bushnaq ZI,Ashfaq R,Leitch AM,Euhus D

更新日期：2007-04-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) was measured in 147 patients at diagnosis of small cell lung cancer; 17% of patients with limited disease and 51% with extensive disease had an abnormal CEA level (greater than 10 ng/ml). The median level was higher in extensive than in limited disease (11 ng/ml and 5.8 ng/ml, respective...

journal_title：Cancer

authors： Laberge F,Fritsche HA,Umsawasdi T,Carr DT,Welch S,Murphy WK,Chiuten DF,Dhingra HM,Farha P,Spitzer G

更新日期：1987-06-15 00:00:00

abstract：:A family with histopathologically proven intraocular malignant melanoma involving two generations is reported. A member of third generation was likely involved by history. Intraocular malignant melanoma, its familial occurrence, its occurrence with multiple malignancies, and its relationship to multiple malignancies o...

journal_title：Cancer

authors： Green GJ,Hong WK,Everett JR,Bhutani R,Amick RM

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:The therapeutic impact of tumor resection is poorly defined. Therefore the current study was conducted. METHODS:A retrospective, 2-institutional study was conducted (1991-1994) to compare the treatment results of stereotactic biopsy plus radiation therapy (99 patients; tumor dose: 60 gray [Gy]) with those o...

journal_title：Cancer

authors： Kreth FW,Berlis A,Spiropoulou V,Faist M,Scheremet R,Rossner R,Volk B,Ostertag CB

更新日期：1999-11-15 00:00:00

abstract：BACKGROUND:The relation between undergoing a single computed tomography (CT) screening for lung carcinoma and the potential long-term impact on smoking status has been equivocal. Perhaps, recommendations from multiple cancer screenings may promote smoking abstinence among individuals at high risk for lung carcinoma. M...

journal_title：Cancer

authors： Townsend CO,Clark MM,Jett JR,Patten CA,Schroeder DR,Nirelli LM,Swensen SJ,Hurt RD

更新日期：2005-05-15 00:00:00

abstract：:The nuclear DNA content of 98 operable breast cancers was determined by flow cytometric analysis using paraffin-embedded tissue. All patients were on follow-up and failure of treatment or recurrences were identified. DNA ploidy data in the form of ploidy status and DNA index (DI) has been correlated with various clini...

journal_title：Cancer

authors： Sharma S,Mishra MC,Kapur BM,Verma K,Nath I

更新日期：1991-12-15 00:00:00

abstract：:A retrospective analysis of a series of 162 patients treated for isolated chest wall recurrence of breast cancer after mastectomy was undertaken. Cumulative survival, distant relapse-free survival, and freedom from local progression after 5 years from the diagnosis of recurrence were 34%, 28%, and 45% respectively. Fi...

journal_title：Cancer

authors： Magno L,Bignardi M,Micheletti E,Bardelli D,Plebani F

更新日期：1987-07-15 00:00:00

abstract：:An in vivo model is described for assessing the antitumor activity of chemotherapeutic agents. Tumors derived from human colon carcinoma cell lines injected into antithymocyte serum (ATS) immunosuppressed mice were used. In this system, both antitumor effects and host toxicity can be quantitated, permitting calculatio...

journal_title：Cancer

authors： Tibbetts LM,Chu MY,Hager JC,Dexter DL,Calabresi P

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Although the biologic characteristics of papillary cystic tumors (PCT) generally indicate a good prognosis, a malignant form has been reported. METHODS:Twenty-two examples of PCT were examined to assess their malignant potential by histologic, flow cytometric, and immunohistochemical studies. RESULTS:Three...

journal_title：Cancer

authors： Nishihara K,Nagoshi M,Tsuneyoshi M,Yamaguchi K,Hayashi I

更新日期：1993-01-01 00:00:00

abstract：:Transcriptional dysregulation induced by disease-defining genetic alterations of proteins in transcriptional machinery is a key feature of cancers. Mediator complex subunit 12 (MED12) is the central architectural subunit in the kinase module of Mediator, a large transcriptional regulatory complex that controls essenti...

journal_title：Cancer

authors： Zhang S,O'Regan R,Xu W

更新日期：2020-03-01 00:00:00

abstract：:The authors retrospectively reviewed the clinicopathologic and immunologic features of 65 consecutive cases of childhood lymphoma reported between 1980 and 1989. Southern blot hybridization was also performed in 23 cases to study their association with Epstein-Barr virus (EBV) and human T-cell leukemia virus type 1 (H...

journal_title：Cancer

authors： Lee SH,Su IJ,Chen RL,Lin KS,Lin DT,Chuu WM,Lin KS

更新日期：1991-11-01 00:00:00

abstract：:A case of osteosarcoma arising in the soft tissue of the larynx in an elderly man is presented with light and electron microscopic documentation. The patient developed chronic hoarseness and a recurring polypoid laryngeal tumor, causing acute airway obstruction. He was treated by total laryngectomy, but he died with m...

journal_title：Cancer

authors： Dahm LJ,Schaefer SD,Carder HM,Vellios F

更新日期：1978-11-01 00:00:00

abstract：:Twenty-two children with acute lymphocytic leukemia (ALL) who had relapsed while on therapy and for whom remissions were successfully reinduced were maintained with a combination of methotrexate, daunomycin, 6-mercaptopurine, prednisone, and vincristine (Djerassi-methotrexate with BOMB). The median duration of remissi...

journal_title：Cancer

authors： Kimball JC,Herson J,Sullivan MP

更新日期：1980-09-01 00:00:00

abstract：:In a randomized series of 70 patients with with colo rectal adenocarcinoma, a comparison of systemic 5-fluorouracil chemotherapy administered as a continuous 120-hours infusion vs. intravenous bolus injection daily for 5 days demonstrated superiority of prolonged intravenous infusion. The most striking advantage of pr...

journal_title：Cancer

authors： Seifert P,Baker LH,Reed ML,Vaitkevicius VK

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND:Some vasoactive drugs have been studied in the hope of altering the vascular permeability and/or blood of tumors to enhance monoclonal antibody (MoAb) uptake. The pretreatment of interleukin-2 (IL-2), one of the vasoactive reagents, produced a generalized vascular permeability, but its function was not tumor...

journal_title：Cancer

authors： Nakamura K,Kubo A

更新日期：1997-12-15 00:00:00

abstract：:The clinical courses of 64 patients undergoing abdominoperineal resection for Stage I lower rectal carcinoma (tumors confined to the muscularis propria without lymph node involvement) were reviewed to identify subsets at risk for failure. Twelve of 12 patients with tumors limited to the submucosa remained disease free...

journal_title：Cancer

authors： Willett CG,Lewandrowski K,Donnelly S,Shellito PC,Convery K,Eliseo R,Compton CC

更新日期：1992-04-01 00:00:00

abstract：:The monitoring utility of serial patterns of a single marker (carcinoembryonic antigen) level and multiple marker (three carbohydrates-fucose, mannose and galactose) levels in patients with small cell carcinoma of the lung was investigated using a quantitative approach. A serial multiple regression (SMR) model was for...

journal_title：Cancer

authors： Woo KB,Waalkes P,Abeloff MD,Ettinger DS,McNitt KL,Gehrke CW

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Adenoid cystic carcinoma (ACC) of the head and neck (ACCHN) is a rare tumor of minor salivary, parotid, and submandibular glands. The biologic behavior of the disease is poorly understood, and nonsurgical treatment strategies have yet to be standardized. The long-term prognosis continues to be guarded, with ...

journal_title：Cancer

authors： Ellington CL,Goodman M,Kono SA,Grist W,Wadsworth T,Chen AY,Owonikoko T,Ramalingam S,Shin DM,Khuri FR,Beitler JJ,Saba NF

更新日期：2012-09-15 00:00:00

abstract：:Fifty-one patients with metastatic breast cancer were randomly allocated to receive either a four drug combination consisting of cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP), or a combination of vincristine, Adriamycin, and cyclophosphamide (VAC) with cross-over on relapse. Objective responses...

journal_title：Cancer

authors： Carmo-Pereira J,Costa FO,Henriques E

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Small areas unstained with Lugol's iodine are often observed in the mucosa surrounding esophageal carcinomas. METHODS:For light microscopic evaluation, the histologic features of 131 small areas unstained by Lugol's iodine in 12 selected cases were investigated. For clinicopathologic evaluation, the numbers...

journal_title：Cancer

authors： Nakanishi Y,Ochiai A,Yoshimura K,Kato H,Shimoda T,Yamaguchi H,Tachimori Y,Watanabe H,Hirohashi S

更新日期：1998-04-15 00:00:00

abstract：:Lymphoid cells from two patients with hand-mirror variant of acute lymphoblastic leukemia (ALL) were studied with various monoclonal antibodies in attempts to determine their derivation and differentiation. The predominant feature of the malignant bone marrow cells was strong reactivity with antibody 3A1, which stains...

journal_title：Cancer

authors： Gramatzki M,Strong DM,Duval-Arnould B,Morstyn G,Schumacher HR

更新日期：1985-01-01 00:00:00