Abstract:
:The descriptive epidemiologic features of bladder cancer and lung cancer in Los Angeles County were studied for the period 1972-1976, using data from the Los Angeles County/University of Southern California Cancer Surveillance Program. The incidence pattern for bladder cancer was found to differ markedly from the pattern observed for lung cancer. As expected, the descriptive pattern for lung cancer closely paralleled the known epidemiology of cigarette smoking; in addition, it was consistent with the expected pattern of an occupationally linked disease. In contrast, the pattern observed for bladder cancer indicated that factors other than cigarette smoking and occupational exposures may be etiologically important. The available descriptive epidemiology of coffee consumption, unlike that of cigarette smoking, is consistent with the pattern of bladder cancer occurrence in Los Angeles. Available analytic studies on the association of bladder cancer and coffee consumption are consistent with a causal relationship.
journal_name
Cancerjournal_title
Cancerauthors
Weinberg DM,Ross RK,Mack TM,Paganini-Hill A,Henderson BEdoi
10.1002/1097-0142(19830215)51:4<675::aid-cncr28205subject
Has Abstractpub_date
1983-02-15 00:00:00pages
675-80issue
4eissn
0008-543Xissn
1097-0142journal_volume
51pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25771
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Lenvatinib is an oral, multitargeted tyrosine kinase inhibitor of the vascular endothelial growth factor receptors 1 through 3 (VEGFR1-VEGFR3), fibroblast growth factor receptors 1 through 4 (FGFR1-FGFR4), platelet-derived growth factor receptor α (PDGFRα), ret proto-oncogene (RET), and v-kit Hardy-Zuckerman...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29395
更新日期:2015-08-15 00:00:00
abstract:BACKGROUND:The objective of this study was to assess the rate and possible reasons for false-negative (FN) reflex human papillomavirus (HPV)-DNA tests. METHODS:The authors reviewed all ThinPrep cervical specimens that were submitted for reflex HPV-DNA testing using the Digene Hybrid Capture II (HC2) method from Januar...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22688
更新日期:2007-06-25 00:00:00
abstract::Autopsy slides from 22 melanoma patients who received bacille Calmette-Guérin BCG immunotherapy and who had a postmortem examination at the UCLA Center for the Health Sciences were examined for the presence of granulomas. Granulomas were found in six patients (29%) who received BCG but not in a group of 25 melanoma pa...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820101)49:1<55::aid-cncr282049
更新日期:1982-01-01 00:00:00
abstract::Of the remote effects of cancer on the neurologic system, paraneoplastic cerebellar degeneration (PCD), characterized by global cerebellar dysfunction, is second only to paraneoplastic neuropathies in frequency. Recent evidence, including the finding of anti-Purkinje cell (now termed anti-Yo) antibodies directed again...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19911015)68:8<1835::aid-cncr2820
更新日期:1991-10-15 00:00:00
abstract::Human prostate specimens from 25 patients provided 15 normal, four benign prostatic hypertrophy (BPH), and seven adenocarcinoma samples which were studied using a polyclonal antibody against prostatic specific antigen (PSA) and protein A-gold complex. Our study showed the presence of gold particles in cytoplasmic vesi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870915)60:6<1288::aid-cncr2820
更新日期:1987-09-15 00:00:00
abstract::The feasibility of employing adjuvant topical mechlorethamine after electron beam therapy in the treatment of patients with mycosis fungoides is demonstrated. Patients treated with a planned adjuvant topical mechlorethamine schedule had a median disease-free interval of 25 months compared to 17 months for the group tr...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(197712)40:6<2851::aid-cncr282040
更新日期:1977-12-01 00:00:00
abstract::The role of 99mTc-pertechnetate thyroid imaging in the preoperative assessment of patients with single palpable thyroid nodules was evaluated. The frequency of cancer in hypofunctional nodules was similar to that found in previous studies with 131I. The 99mTc-pertechnetate image allowed a reliable separation of pathol...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197601)37:1<258::aid-cncr2820370
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:There are few reports comparing the clinicopathologic features of sarcomas of the aorta (SA), sarcomas of the inferior vena cava (SIVC), and sarcomas of the pulmonary artery (SPA). METHODS:The authors retrospectively reviewed 11 SA, 16 SIVC, and 16 SPA, and compared clinical, pathologic, and immunohistochem...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930301)71:5<1761::aid-cncr2820
更新日期:1993-03-01 00:00:00
abstract::In order to investigate the relationship between histologic findings and clinical behavior in angioimmunoblastic lymphadenopathy (AILD), 44 patients with AILD were reviewed. These patients comprised 24 men and 20 women with age range from 25 to 84 years of age (median, 64 years). Lymphadenopathy was observed in all pa...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890415)63:8<1625::aid-cncr2820
更新日期:1989-04-15 00:00:00
abstract:BACKGROUND:Ewing's sarcomas, osteosarcomas, and rhabdomyosarcomas are significantly more responsive to chemotherapy than other sarcomas. Adjuvant chemotherapy is used routinely based on data from randomized trials. Although a percentage of children with locally advanced or metastatic tumors remain curable, few data exi...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract:BACKGROUND:Cisplatin and carboplatin are essential to management of advanced-stage epithelial ovarian carcinoma. No published data exist regarding carboplatin dose intensity importance in ovarian cancer, nor are there data for the effect of age on the ability to deliver dose-intensive carboplatin. METHODS:Retrospectiv...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.2820710225
更新日期:1993-01-15 00:00:00
abstract:BACKGROUND:African Americans are diagnosed more frequently with colorectal carcinoma at a later stage compared with Caucasians. One potential reason for the disparity is a lower rate of screening examinations. METHODS:Using Outpatient and Physician-Supplier claims for all Medicare beneficiaries age > or = 65 years in ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20014
更新日期:2004-01-15 00:00:00
abstract:BACKGROUND:It has been established that comparative genomic hybridization (CGH) on Papanicolaou-stained cervical smears can be used to identify chromosomal imbalances. METHODS:In this study, the authors identified normal and dysplastic squamous epithelial cells cytologically, eliminated surrounding bacteria or leukocy...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19981225)84:6<375::aid-cnc
更新日期:1998-12-25 00:00:00
abstract::In 175 premenopausal breast cancer patients, a history of oral contraceptive (OC) use before 20 years of age was significantly associated with higher tumor cell proliferative activity, as indicated by a higher S-phase fraction (SPF), and a higher fraction of DNA aneuploid tumors, compared with later or never users (P ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910301)67:5<1285::aid-cncr2820
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:Despite extensive investigation, the role of MDR of human cancer remains unclear. Canine lymphoma is a spontaneously arising correlate of human non-Hodgkin's lymphoma that may complement other in vivo models for investigation of issues related to MDR. METHODS:Immunoreactivity of primary antibodies to the hu...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960501)77:9<1892::AID-CN
更新日期:1996-05-01 00:00:00
abstract::To investigate histologic prognostic factors in soft tissue sarcomas (STS), multivariate analysis was performed on 236 patients with complete clinical information. These included 141 males and 95 females with an age range from 1 to 85 years (median, 47.6 years). Histologically, malignant fibrous histiocytoma (33.5%) w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880901)62:5<994::aid-cncr28206
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:Breast carcinoma survivors are the largest segment of the expanding cancer survivor community. As a result, there has been increasing discussion of the safety and efficacy of hormone replacement therapy for women with a past history of breast carcinoma. Little is known about the willingness of older breast c...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::The case of a 49-year-old man with the diagnosis of angioimmunoblastic lymphadenopathy is reported. The patient survived a stormy clinical course. The corticosteroids improved dramatically the clinical picture although the patient developed a staphylococcal septicemia. Before treatment immunological studies were done ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197808)42:2<447::aid-cncr2820420
更新日期:1978-08-01 00:00:00
abstract:BACKGROUND:National and international bodies acknowledge the benefit of exercise for people with cancer, yet limited accessibility to related programing remains. Given their involvement in managing the disease, cancer centers can play a central role in delivering exercise-oncology services. The authors developed and im...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32297
更新日期:2019-10-01 00:00:00
abstract::Routine morphologic and cytochemical study of the leukemic cells of a 13-month-old child did not permit definitive determination of either a lymphoid or a myeloid cell origin. However, ultrastructural cytochemical analysis revealed platelet peroxidase (PPO) reactivity. The malignant cells expressed PPO in both unfixed...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841001)54:7<1423::aid-cncr2820
更新日期:1984-10-01 00:00:00
abstract::A marked increase in specific immunogenicity of tumor cells is induced upon incorporation of cholesteryl hemisuccinate (CHS) into the cell membrane, which presumably promotes the expression of latent tumor-associated antigens. Immunotherapy with CHS-treated and irradiated tumor cells as vaccine was found to be very ef...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19860801)58:3<650::aid-cncr28205
更新日期:1986-08-01 00:00:00
abstract::Treatment with BCG (Bacillus Calmette-Guérin) followed by irradiation was attempted to improve response to therapy by cutaneous metastases from malignant skin melanomas. Both agents were applied in low doses, known to cause minimal side effects. Nineteen patients, divided into three groups, entered the clinical trial....
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820915)50:6<1100::aid-cncr2820
更新日期:1982-09-15 00:00:00
abstract::Levels of immunoreactive ACTH and calcitonin (CT), as well as CEA, were determined serially in 144 patients with lung cancer and in 62 patients with metastatic carcinoma to the lungs. Patients with neoplasms not involving the lungs, with nonmalignant blood dyscrasias, and with chronic obstructive pulmonary disease wer...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810515)47:10<2485::aid-cncr282
更新日期:1981-05-15 00:00:00
abstract:BACKGROUND:Ewing sarcoma family of tumors (ESFTs) are the second most common bone tumor, that most often affects persons ages 3-40 years. The ESFTs rely on signaling through the insulin-like growth factor-1 receptor (IGF-1R) for growth and transformation. The current studies were performed to determine the levels of IG...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20011201)92:11<2941::aid-cncr100
更新日期:2001-12-01 00:00:00
abstract::The International Breast Cancer Study Group (formerly the Ludwig Group) has conducted nine clinical trials since 1978 (see the Appendix for participants and authors). Biologic hypotheses related to the combined use of chemotherapy and endocrine therapy in women with operable breast cancer were tested. Questions of tim...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940801)74:3+<1139::aid-cncr282
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to analyze the extent of hypoxia in prostate carcinoma tumors using the Eppendorf pO(2) microelectrode and correlate this with pretreatment characteristics and prognostic factors. METHODS:Custom-made Eppendorf pO(2) microelectrodes were used to obtain pO(2) measurements from th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20001101)89:9<2018::aid-cncr19>3
更新日期:2000-11-01 00:00:00
abstract::A comprehensive immunologic and serologic analysis was performed on 31 untreated patients with Hodgkin's disease. Immune evaluations stressed T-cell functional activity and included traditional parameters (PHA responsiveness and delayed hypersensitivity skin reactivity), as well as newer functional assays (T-cell colo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810815)48:4<964::aid-cncr28204
更新日期:1981-08-15 00:00:00
abstract::Fifty-three patients with advanced lymphocytic lymphoma were randomly assigned to treatment with the combination cyclophosphamide, vincristine, and prednisone (CVP) or the same agents used successively in maximal doses (C-V-P). Complete remissions occurred in 68% with CVP and 48% with C-V-P. For patients with nodular ...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(197801)41:1<23::aid-cncr28204101
更新日期:1978-01-01 00:00:00
abstract::The design of many antineoplastic agents has been based on atom or group replacement in normal metabolites. New dimensions are being added to this approach by the synthesis of transition state, bisubstrate and "suicide" inhibitors. These provide greater potency and in some cases selectivity. Leads for differential sen...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197707)40:1+<529::aid-cncr282040
更新日期:1977-07-01 00:00:00