Multivariate analysis for histologic prognostic factors in soft tissue sarcomas.

Abstract:

:To investigate histologic prognostic factors in soft tissue sarcomas (STS), multivariate analysis was performed on 236 patients with complete clinical information. These included 141 males and 95 females with an age range from 1 to 85 years (median, 47.6 years). Histologically, malignant fibrous histiocytoma (33.5%) was the most common type followed by synovial sarcoma (11%), liposarcoma (10%), rhabdomyosarcoma (7%), and leiomyosarcoma (7%). Monofactorial analysis revealed that sex, depth, location, histologic grade, cellularity, frequency of mitosis, and necrosis were significant prognostic factors. By multivariate analysis, only frequency of mitosis and depth of tumors were proved to be of prognostic significance. The prognostic importance of the frequency of mitosis as shown in previous and the present studies indicates that further investigation of the cell proliferation in patients with STS is required.

journal_name

Cancer

journal_title

Cancer

authors

Tsujimoto M,Aozasa K,Ueda T,Morimura Y,Komatsubara Y,Doi T

doi

10.1002/1097-0142(19880901)62:5<994::aid-cncr28206

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

994-8

issue

5

eissn

0008-543X

issn

1097-0142

journal_volume

62

pub_type

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